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Evaluation of Antibacterial and Antidiarrhoeal Activities of <i>Feronia limonia</i>Leaf Extract

American Journal of Plant Sciences 2013年第11期4卷 2181-2185页

作者： Mohammad Abdul Motalib Momin Mizanur Rahaman Khan Johir Rayhan Afrina Afrose Sohel Rana Anjuman ara Begum Department of Pharmacy Jahangirnagar University Savar Ban-gladesh Department of Pharmacy University of Science and Technology Chittagong Chittagong Bangladesh

The present study was carried out to investigate possible antibacterial and antidiarrhoeal activities of ethanol extract of Feronia limonia leaves. Phytochemical analysis of the crude extract was performed to detect presence of different kinds of phytoconstituents. The antibacterial activity was investigated against four Gram positive and four Gram negative bacteria by using disc diffusion method. The plant extract showed moderate antibacterial activity against Gram positive bacteria namely Staphylococcus saprophyticus and Staphylococcus pyogenes and all tested Gram negative bacteria namely Escherichia coli, Shigella boydii, Shigella dysentery and Shigella flexneri in dose dependant manner. The results of castor oil-induced diarrhoeal study showed that Feronia limonia extract significantly reduced the severity & frequency of diarrhoea in mice at a higher dose of 500 mg/kg compared with the standard drug loperamide (25 mg/kg). The present study clearly supports the medicinal value of this plant. The overall results indicate the possibility of presence of some active principles in the plant extract possessing antibacterial and antidiarrhoeal actions.

关键词： Phytochemical Screening Antimicrobial Antidiarrhoeal Feronia limonia

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高山被孢霉生产ara发酵条件的优化研究

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食品科技 2014年第11期39卷 17-26页

作者：班甲陈骏佳王帆胡雪梅班雯婷广州甘蔗糖业研究所广东省甘蔗改良与生物炼制重点实验室广州510316

对ara产生菌高山被孢霉的培养条件进行了研究,通过摇瓶实验考察了碳源、碳氮比、初始pH值、接种量和微量元素等对ara的影响。结果发现在培养基中使用葡萄糖为碳源,碳氮比维持在40：1～50：1之间,初始pH6,接种量10%,添加VB1 100 mg/L、VB... 详细信息

对ara产生菌高山被孢霉的培养条件进行了研究,通过摇瓶实验考察了碳源、碳氮比、初始pH值、接种量和微量元素等对ara的影响。结果发现在培养基中使用葡萄糖为碳源,碳氮比维持在40：1～50：1之间,初始pH6,接种量10%,添加VB1 100 mg/L、VB12 0.5 mg/L、生物素0.5mg/L、泛酸钙120 mg/L和谷氨酸1 g/L是较优配方（优化培养基A）。实验同时对比了使用单一氮源及混合氮源对高山被孢霉发酵产ara的影响,结果发现使用混合氮源更有利于高山被孢霉发酵产ara,混合氮源得到的ara产量是使用单一氮源的2倍,且其含量占总油脂的44.5%,在此基础上获得优化培养基B。

关键词：高山被孢霉花生四烯酸分批发酵响应面法

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The Impact of the Essential Fatty Acids (EFA) in Human Health

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Open Journal of Endocrine and Metabolic Diseases 2015年第7期5卷 98-104页

作者： Alberto Krayyem Arbex Vagner Rosa Bizarro Julio Cesar Salles Santos Lis Marina Mesquita araújo Ana Luísa Conceicao de Jesus Minelli Salles Alves Fernandes Marcela Miranda Salles Denise Rosso Tenório Wanderley Rocha Aline Marcadenti Division of Endocrinology Faculdade IPEMED de Ciências Médicas (IPEMED) Rio de Janeiro Brazil Visiting Scientist of the Harvard School of Public Health Harvard University Boston USA Postgraduate Studies Program in Cardiology Instituto de Cardiologia/Fundacao Universitária de Cardiologia do Rio Grande do Sul (IC/FUC) Porto Alegre Brazil Department of Nutrition Universidade Federal de Ciências da Saúde de Porto Alegre (UFSCPA) Porto AlegreBrazil

Linoleic (LA) and α-linolenic acids (ALA) are considered essential fatty acids (EFA) because they are not produced by the human body. This way, EFAs sources must come from the diet. The primary dietary source of n-3 fatty acids is ALA, found in seeds and seed oils. Other important sources are fish oils such as tuna, salmon and herring. Currently, numerous studies suggest possible benefits of essential fatty acids in human health, such as in cardiovascular, cognitive and eye health, and also during pregnancy and childhood. This paper also discusses the impact of fatty acids in human metabolism, and the available evidence regarding its risks. It addresses the relevant debate regarding a general ban of trans fatty acids (TFA) from the world food market, because of the cardiovascular risks associated with its consumption.

关键词： Fatty Acids Linoleic Acid Alpha-Linolenic Acid Cardiovascular Health Trans Fatty Acids

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阿柔比星联合中剂量阿糖胞苷诱导治疗难治和复发性急性髓样白血病的疗效

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肿瘤 2009年第2期29卷 184-187页

作者：刘班薄兰君梁爱斌熊红付建非陈毓华丁懿吴昊张文君同济大学附属同济医院输血科上海200065 同济大学附属同济医院血液科上海200065

目的:探讨阿柔比星(aclacinomycin,Acla)联合中剂量阿糖胞苷(intermediate-dose cytarabine,IDara-C)治疗难治和复发性急性髓样白血病(acute myeloid leukemia,AML)的疗效和不良反应。方法:26例难治和复发性AML患者接受Acla联合IDara-C方案进行解救治疗,评估不良反应和疗效。结果:26例患者接受2个周期Acla联合IDara-C方案的化疗后,12例完全缓解,7例部分缓解,7例无缓解,1例因治疗过程中发生严重感染而死亡。结论:Acla联合IDara-C方案可作为难治和复发性AML再诱导治疗的一种选择,患者大多耐受良好。

关键词：白血病, 髓样, 急性复发阿柔比星阿糖胞苷

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微生物发酵法生产花生四烯酸油脂的研究进展

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生物加工过程 2013年第4期11卷 72-78页

作者：周正雄卢英华班甲陈骏佳广州甘蔗糖业研究所广东省甘蔗改良与生物炼制重点实验室广州510316 厦门大学化学化工学院化学工程与生物工程系厦门361005

花生四烯酸(ara)是一种重要的脂肪酸,现在主要由生物法生产,本文综述了高山被孢霉发酵生产花生四烯酸油脂的菌落形态控制及其代谢途径,以期为相关的研究者提供参考。

关键词：花生四烯酸油脂高山被孢霉形态优化限速步骤苹果酸酶

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong ban Tripamo bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad banaras Hindu University Institute of ScienceVaranasi bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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