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Predictors of acute gastrointestinal bleeding in diabetic ketoacidosis:a retrospective observational study in minority population

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Gastroenterology Report 2017年第4期5卷 293-297,I0002页

作者： Kanthi Rekha Badipatla Preeti Jadhav Sushma Vaddigiri Bharat Bajantri Amandeep Singh chaitanya chandrala Vijay S Are Suresh Kumar Nayudu Department of Medicine Bronx Lebanon Hospital CenterIcahn School of Medicine at Mount SinaiBronxNew YorkNYUSA Division of Gastroenterology Bronx Lebanon Hospital CenterIcahn School of Medicine at Mount SinaiBronxNew YorkNYUSA Division of Pulmonary and Critical Care Bronx Lebanon Hospital CenterIcahn School of Medicine at Mount SinaiBronxNew YorkNYUSA Division of Cardiology Bronx Lebanon Hospital CenterIcahn School of Medicine at Mount SinaiBronxNew YorkNYUSA

Background:Diabetic ketoacidosis(DKA)is a common acute complication of diabetes mellitus requiring aggressive medical *** attempted to study the incidence and various clinical and laboratory variables associated with acute gastrointestinal bleeding(AGIB)and acute upper AGIB(AUGIB)in patients with ***:We conducted a retrospective chart review of all the patients admitted to our hospital with DKA between January 2010 and December *** collected demographic,clinical,laboratory,endoscopy and hospitalization details using an electronicmedical-record *** were divided into two groups based on the occurrence of gastrointestinal ***:A total of 234 patients with DKA were admitted during this period,of which 27(11.5%)patients had documented *** majority of patients had hematemesis(n=22,9.4%)except two had rectal and three had occult *** did not notice any difference in age,gender and ethnicity distribution between the two *** was no difference in the serum levels of electrolytes,anion gap,pH and hemoglobin A1C between the two ***,patients with AGIB had significantly higher initial blood glucose levels(738 vs 613 mg/dL,p=0.014).There was also increased mortality(7.4%vs 4.8%)in patients with AGIB,but this did not reach statistical ***:We conclude that higher initial serum blood glucose was associated with increased incidence of AGIB in patients admitted with *** also noted increased in-patient mortality in patients with DKA who had AGIB,even though statistically *** aggressive measures to correct blood glucose levels may result in decreased incidence of AGIB,thereby reducing mortality during hospitalization in patients with DKA.

关键词： diabetic ketoacidosis gastrointestinal bleeding mortality

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