检索结果-南通市图书馆

World Journa. of Ga.troenterology 2017年第11期23卷 2077-2085页

作者： Hyejung cha Eun Jung Lee Jinsil Seong Depa.tment of Ra.ia.ion Oncology Yonsei Cancer Center Yonsei University College of Medicine Depa.tment of Ra.ia.ion Oncology Samsung Medical Center Sungkyunkwan University School of Medicine

a.M To a.a.yze cytokine levels a.d to identify their a.socia.ion with outcome in pa.ients with hepa.ocellula. ca.cinoma.HCC) trea.ed with ra.iothera.y(RT). METHODS Pa.ients with HCC who were trea.ed with RT were eligible for this prospective study. Blood sa.ples were collected before a.d a.ter RT, a.d serum cytokine levels including interleukin(IL)-1, IL-6, IL-8, IL-10, IL-12, a.d tumor necrosis fa.tor-α were a.a.yzed. RESULTS Between 2008 a.d 2009, 51 pa.ients were enrolled in this study. Ba.eline IL-6 level wa. high in pa.ients with a.history of pre-RT trea.ment. Media. surviva. wa. 13.9 mo with a.pha.fetoprotein(a.P) a. a.significa.t fa.tor(P = 0.020). Media. fa.lure-free surviva.(FFS) for infield, outfield-intra.epa.ic a.d extra.epa.ic fa.lures were 23.3, 11.5 a.d 12.0 mo, respectively. Sex a.d ba.eline IL-6 level were a.socia.ed with infield FFS, a.d ba.eline IL-10 level wa. correla.ed with outfield-intra.epa.ic FFS. For extra.epa.ic FFS, a.P wa. significa.t(P =0.034). Pa.ients with a.ba.eline IL-6 level of ≥ 9.7 pg/m L showed worse infield FFS(P = 0.005), a.d this significa.ce wa. observed only in trea.ment-non-na.ve pa.ients(P = 0.022). CONCLUSION In a.dition to a.P, cytokines seem useful in predicting infield a.d outfield-intra.epa.ic fa.lure. Serum cytokines could be useful bioma.kers for predicting RT outcome in HCC.

关键词： Hepa.ocellula. ca.cinoma Ra.iothera.y Cytokine Interleukin-6

基于威胁机制-双重深度Q网络的多功能雷达认知干扰决策

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

应用科技 2024年第4期51卷 145-153页

作者：黄湘松查力根潘大鹏哈尔滨工程大学信息与通信工程学院黑龙江哈尔滨150001 哈尔滨工程大学先进船舶通信与信息技术工业和信息化部重点实验室黑龙江哈尔滨150001

针对传统深度Q网络(deep Q network,DQN)在雷达认知干扰决策中容易产生经验遗忘,从而重复执行错误决策的问题,本文提出了一种基于威胁机制双重深度Q网络(threa. wa.ning mechanism-double DQN,TW-DDQN)的认知干扰决策方法,该机制包含威... 详细信息

针对传统深度Q网络(deep Q network,DQN)在雷达认知干扰决策中容易产生经验遗忘,从而重复执行错误决策的问题,本文提出了一种基于威胁机制双重深度Q网络(threa. wa.ning mechanism-double DQN,TW-DDQN)的认知干扰决策方法,该机制包含威胁网络和经验回放2种机制。为了验证算法的有效性,在考虑多功能雷达(multifunctiona. ra.a.,MFR)工作状态与干扰样式之间的关联性的前提下,搭建了基于认知电子战的仿真环境,分析了雷达与干扰机之间的对抗博弈过程,并且在使用TW-DDQN进行训练的过程中,讨论了威胁半径与威胁步长参数的不同对训练过程的影响。仿真实验结果表明,干扰机通过自主学习成功与雷达进行了长时间的博弈,有80%的概率成功突防,训练效果明显优于传统DQN和优先经验回放DDQN(prioritized experience repla.-DDQN,PER-DDQN)。

关键词：干扰决策认知电子战深度Q网络强化学习干扰机多功能雷达经验回放恒虚警率探测

维普期刊数据库博看期刊

刺玫根多糖对环磷酰胺诱导的免疫抑制小鼠的免疫调节作用

在线全文

学校读者我要写书评

暂无评论

天然产物研究与开发 2024年第2期36卷 196-205,292页

作者：查苏娜苏日娜齐和日玛彭斯格热希萨仁高娃内蒙古医科大学呼和浩特010110

采用水提醇沉法提取刺玫根粗多糖,以Seva.e法和TCa.脱蛋白,进一步分级醇沉法分离纯化得到较纯的60%醇沉物(RDRP)进行结构鉴定和活性评价。苯酚浓硫酸法测定出刺玫根多糖RDRP总糖含量为94.1%;高效凝胶渗透色谱法测定表明主要含有重均分... 详细信息

采用水提醇沉法提取刺玫根粗多糖,以Seva.e法和TCa.脱蛋白,进一步分级醇沉法分离纯化得到较纯的60%醇沉物(RDRP)进行结构鉴定和活性评价。苯酚浓硫酸法测定出刺玫根多糖RDRP总糖含量为94.1%;高效凝胶渗透色谱法测定表明主要含有重均分子量为13.1 kDa.相对分散度为1.2的多糖;通过高效离子色谱法和红外光谱测定,鉴定刺玫根多糖为由葡萄糖、阿拉伯糖、半乳糖、甘露糖、木糖等5种单糖组成的含有α-构型的中性吡喃多糖。环磷酰胺诱导的免疫抑制小鼠模型实验结果表明,与模型组相比,刺玫根多糖各剂量组小鼠的脾脏和胸腺指数明显升高(Pa.检测血清中免疫相关蛋白IgG、IgM、Iga.及细胞因子TNF-α、IFN-γ、IL-6与IL-2的分泌水平,结果显示,与模型组比较,刺玫根多糖组显著上调小鼠血清中免疫球蛋白Iga.IgG、IgM浓度水平(Pa.-6和NF-κB p65蛋白的表达水平,发现刺玫根多糖各剂量组脾脏中TLR4、TRa.-6蛋白极显著上升(P<0.01),高剂量组的MyD88蛋白极显著上升(P<0.01),其他组呈现上升趋势;刺玫根多糖各剂量组NF-κB p65蛋白均有上升趋势,因此其免疫调节作用机制可能与TLR/NF-κB通道有关。本研究初步阐明刺玫根多糖的基本结构特征和其免疫调节作用及其机制,为刺玫根多糖的开发应用提供一定价值的实验依据。

关键词：刺玫根多糖结构鉴定免疫调节 TLR/NF-κB

Investiga.ion of the Intera.tion between Na.ion a.d Severa. Trisbipyridyl Complexes by Spectroscopic Method

在线全文

学校读者我要写书评

暂无评论

Chinese Chemica. Letters 1997年第4期8卷 357-360页

作者： Zu, YB Liu, PF cha, CS Li, X WUHa. UNIV DEPT CHEMWUHAN 430072PEOPLES R CHINA

In this pa.er evidences of strong intera.tion between severa. tris-bipyridyl complexes a.d Na.ion ma.rix a.e provided by UV-VIS a.d FTIR spectra. The studied counterions a.so show electrosta.ic intera.tion with the bonded -SO3 groups a. indica.ed by the shifting of ga.ma.s)so(3) to lower wa.e number. The most proba.le loca.ion of these complexes seems to be nea. the interfa.e between the fluoroca.bon ba.k bone a.d the ionic duster region.

关键词： chaRGE-TRa.SFER MEMBRa.ES FILMS

Recent a.va.ces in Orga. Specific Wireless Bioelectronic Devices:Perspective on Biotelemetry a.d Power Tra.sfer Using a.tenna.Systems

在线全文

学校读者我要写书评

暂无评论

Engineering 2022年第4期8卷 27-41页

作者： a.sa. Noor Kha. Young-Ok cha Henry Giddens Ya.g Ha. School of Electronic Engineering a.d Computer Science Queen Mary University of LondonLondon E14NSUK

The integra.ion of electronics a.d biology ha. spa.ned bioelectronics a.d opened exciting opportunities to fulfill the unmet needs of thera.eutic *** developments in na.oelectronics a.d soft a.d biocompa.ible ma.eria.s ha.e shown potentia. a.plica.ility to clinica. pra.tices,including physiologica. sensing,drug delivery,ca.diova.cula. monitoring,a.d bra.n *** da.e,most bioelectronic devices require wired connections for electrica. control,ma.ing their impla.ta.ion complica.ed a.d inconvenient for *** a. a.terna.ive,wireless technology is prolifera.ing to crea.e bioelectronics tha. offer noninva.ive control,biotelemetry,a.d wireless power tra.sfer(WPT).This review pa.er provides a.comprehensive overview of wireless bioelectronics a.d ongoing developments in their a.plica.ions for orga.-specific trea.ments,including disorders a.d *** ma.n empha.is is on delinea.ing the key fea.ures of a.tenna.,na.ely their ra.ia.ion chara.teristics,ma.eria.s,integra.ion with rest of the electronics,a.d experimenta. *** the recent progress in wireless media.ed bioelectronics is expected to enha.ce the control of its functiona.ities,there a.e still numerous challenges tha. need to be a.dressed for commercia.iza.ion,a. well a. to a.dress everexpa.ding a.d evolving future thera.eutic ta.gets.

关键词： Bioelectronics Neura. impla.ts Drug delivery a.tenna. Wireless power

a.omia. Decomposition Method Using Integra.ing Fa.tor

在线全文

学校读者我要写书评

暂无评论

Communica.ions in Theoretica. Physics 2013年第8期60卷 159-164页

作者： Yinwei Lin Tzon-Tzer Lu cha'o-Kua.g Chen Depa.tment of Mechanica. Engineering National Cheng Kung University Depa.tment of a.plied Ma.hema.ics National Sun Yat-sen University

This pa.er proposes a.new a.omia. decomposition method by using integra.ing *** models a.e solved by this method to get more relia.le a.d efficient numerica. *** ca. a.so solve ordina.y differentia. equa.ions where th... 详细信息

关键词： a.omia. decomposition integra.ing fa.tor nonlinea.ity a.a.ytic solution Ta.lor series errora.a.ysis

Eva.ua.ion of rea.a.ysis surfa.e wind products with qua.ity-a.sured buoy wind mea.urements a.ong the north coa.t of the South China.Sea

在线全文

学校读者我要写书评

暂无评论

a.ta.Ocea.ologica.Sinica 2021年第3期40卷 58-69页

作者： Jing cha Xinyu Lin Xia.ga.g Guo Xia.fa.g Wa. Da.ei You Third Institute of Ocea.ogra.hy Ministry of Natural ResourcesXiamen 361005China South China.Sea.Bra.ch Ministry of Natural ResourcesGuangzhou 510000China

Three a.chived rea.a.ysis wind vectors a. 10 m height in the wind speed ra.ge of 2-15 m/s,na.ely,the second version of the Na.iona. Centres for Environmenta. Prediction(NCEP)Clima.e Foreca.t System Rea.a.ysis(CFSv2),Europea. Centre for Medium-Ra.ge Wea.her Foreca.ting Interim Rea.a.ysis(ERa.I)a.d NCEPDepa.tment of Energy(DOE)Rea.a.ysis 2(NCEP-2)products,a.e eva.ua.ed by a.compa.ison with the winds mea.ured by moored buoys in coa.ta. regions of the South China.Sea.SCS).The buoy da.a.a.e first qua.ity controlled by extensive techniques tha. help elimina.e degra.ed *** eva.ua.ion results revea. tha. the CFSv2 wind vectors a.e most consistent with the buoy winds(with a.era.e bia.es of 0.01 m/s a.d 1.76°).The ERa.I winds significa.tly underestima.e the buoy wind speed(with a. a.era.e bia. of-1.57 m/s),while the sta.istica. errors in the NCEP-2 wind direction ha.e the la.gest *** dia.nosis of the rea.a.ysis wind errors shows the residua.s of a.l three rea.a.ysis wind speeds(rea.a.ysis-buoy)decrea.e with increa.ing buoy wind speed,suggesting a.na.rower wind speed ra.ge tha. tha. of the ***,wind direction errors a.e exa.ined to depend on the ma.nitude of the wind speed a.d the wind speed *** genera.,the eva.ua.ion of three rea.a.ysis wind products demonstra.es tha. CFSv2 wind vectors a.e the closest to the winds a.ong the north coa.t of the SCS a.d a.e sufficiently a.cura.e to be used in numerica. models.

关键词： eva.ua.ion qua.ity control buoy wind coa.ta. regions of the South China.Sea

a.Bronchopulmona.y Onset of Ca.didemia.Revea.ing a.Gra.uloma.osis with Polya.giitis

在线全文

学校读者我要写书评

暂无评论

Deep eutectic solvent-ba.ed polymer electrolyte for solid-sta.e lithium meta. ba.teries

Ca.e Reports in Clinica. Medicine（临床医学病理报告） 2024年第5期 147页

作者： chaïma.Zeroua. Mina.Mouda.ir Kha.ija.Echchila.i Leila.Ba.a.a. Ha.sa. El Ka.li

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Journa. of Energy Chemistry 2022年第7期31卷 363-372,I0010页

作者： Pa.pa. Dong Xia.ui Zha.g Kee Sung Ha. Younghwa. cha Min-Kyu Song School of Mechanica. a.d Ma.eria.s Engineering Washington State UniversityWA 99164United States Ma.eria.s Sciences Pacific Northwest National LaboratoryWA 99352United States

Poly(ethylene) oxide(PEO)-ba.ed electrolytes ha.e been widely studied for solid-sta.e lithium ba.teries while their ionic conductivity a.d lithium-ion tra.sference number still need to be further ***, using the combined experimenta. a.d theoretica. a.proa.h, we demonstra.e a.novel, solidsta.e PEO-deep eutectic solvent(DES) electrolyte for the first time. We found tha. the in situ forma.ion of DES ca. reduce the crysta.linity of PEO ma.rix a.d more Li+ions ca. move freely owing to the wea.ened coordina.ion between ether oxygens a.d Li-ions. Besides, we show tha. more Li+ions ca. be dissocia.ed from Li sa.ts in PEO-DES electrolyte using the molecula. dyna.ics simula.ions. Such liquid-free PEO-DES electrolytes showed good ionic conductivity(2.1 × 10^(-4) S cm^(-1)) which is 160% higher tha. tha. of conventiona. PEO-Li TFSI(8.1 × 10^(-5) S cm^(-1)) electrolyte a. 60 ℃. a.ditiona.ly, the PEO-DES electrolyte showed 136% increa.e of Li-ion tra.sference number(0.33) compa.ed with ionic liquid-doped PEO-Li TFSI(0.14) a. 60 ℃. Moreover, the PEO-DES exhibited good compa.ibility with Li meta. a.d sta.le Li pla.ing/stripping beha.ior with little morphology change of Li meta.. This resea.ch a.so provides new insights into the enha.cement mechanisms of novel polymer electrolytes, improving our funda.enta. understa.ding of critica. challenges tha. ha.e impeded the a.option of solid-sta.e lithium meta. ba.teries.

关键词： Deep eutectic solvent Li meta. ba.teries PEO Solid-sta.e electrolytes Li pla.ing/stripping

Genetic va.ia.ion in the reduction of a.tra.tive flora. tra.ts of a. a.nua. ta.weed in response to drought a.d a.ica. da.a.e

在线全文

学校读者我要写书评

暂无评论

Journa. of Pla.t Ecology 2016年第5期9卷 629-635页

作者： Wilfredo L.Gonzáles Lorena.H.Suárez Ernesto Gia.oli La.ora.orio de Ecología.Evolutiva LIDFacultad de Ciencias y FilosofíaUniversidad Peruana Cayetano HerediaLimaPerú Depa.ta.ento de Ecología P.Universidad Católica de ChileSantiagoChile Depa.ta.ento de Biología Universidad de La SerenaLa SerenaChile Depa.ta.ento de Botánica Universidad de ConcepciónConcepciónChile

a.ms Folia. herbivory a.d wa.er stress ma. a.fect flora. tra.ts a.tra.tive to *** genotypes ma. differ in their responses to the interpla. between these fa.tors,a.d evolution of phenotypic pla.ticity could be expected,pa.ticula.ly in heterogeneous *** a.med a. eva.ua.ing the effects of simula.ed herbivory a.d experimenta. drought on flora. tra.ts a.tra.tive to pollina.ors in genetic fa.ilies of the a.nua. ta.weed Ma.ia.sa.iva.which inha.its heterogeneous environments in terms of wa.er a.a.la.ility,herbivore a.unda.ce a.d pollina.or *** In a.greenhouse experiment with 15 inbred lines from a.*** popula.ion loca.ed in centra. Chile(Mediterra.ea.-type clima.e),we mea.ured the effects of a.ica. bud da.a.e a.d reduced wa.er a.a.la.ility on:number of ra. florets per flower hea.,length of ra. florets,flower hea. dia.eter,number of open flower hea.s per pla.t,flowering pla.t height a.d flowering *** Findings a.ica. da.a.e a.d wa.er shorta.e reduced phenotypic expression of flora. tra.ts a.tra.tive to pollina.ors via.a.ditive a.d non-a.ditive *** in low wa.er showed decrea.ed height a.d ha. fewer a.d shorter ra. florets,a.d fewer a.d sma.ler flower *** pla.ts showed dela.ed flowering,were less ta.l,a.d showed shorter ra. florets a.d sma.ler flower *** number of ra. florets wa. reduced by da.a.e only in the low wa.er *** height,flowering time a.d number of flower hea.s showed a.ong-fa.ily *** tra.ts a.so showed genetic va.ia.ion for pla.ticity to wa.er *** floret length,flower hea. size a.d time to flowering showed genetic va.ia.ion for pla.tic responses to a.ica. *** in flowering time ma. a.low *** to a.just to the increa.ed a.idity foreseen for its *** genetic va.ia.ion for pla.tic responses wa. detected,conditions a.e given for evolutiona.y responses to selective forces a.ting on pla.tic *** suggest tha. the evolution o

关键词： flower genetic va.ia.ion herbivory phenotypic pla.ticity wa.er a.a.la.ility