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总量控制下环境容量产权交易及政府行为分析

四川环境 2003年第3期22卷 49-52,65页

作者：吕伟明江阴市环境监测站江苏江阴214431

利用经济学的原理 ,本文分析了环境容量的经济特点 (不是环境容量产权交易的特征 ) ,提出了环境容量产权交易的可行性和必要性。

关键词：总量控制环境容量产权交易

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对数学教学的困境与出路的思索

山西广播电视大学学报 2003年第3期8卷 57-58页

作者：贺利敏山西建筑职业技术学院山西太原030006

高职数学教学面临的现状不容乐观 ,要走出困境 ,就要改革教学内容和教学方法。

关键词：高等数学专业倾斜教材教师

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美国环境法上的民众诉讼制度

四川环境 2002年第1期21卷 91-94页

作者：巫玉芳广东省汕头大学法学院广东汕头515063

民众诉讼制度作为自力救济措施是美国环境保　护法律制度中的特色之一。该制度赋予民众借助法院的权力，监督行政机关执行环境保护法　律以达到加强执法或消除污染、改善环境的目的。研究该制度对我国加强环境保护法律的执　行、提高公... 详细信息

民众诉讼制度作为自力救济措施是美国环境保　护法律制度中的特色之一。该制度赋予民众借助法院的权力，监督行政机关执行环境保护法　律以达到加强执法或消除污染、改善环境的目的。研究该制度对我国加强环境保护法律的执　行、提高公众的环境保护意识具有一定的作用。

关键词：民众诉讼制度环境保护法美国环境权

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纺织品来样分析的步骤和方法

四川纺织科技 2004年第1期 44-46页

作者：黄艳丽常州纺织服装职业技术学院江苏常州213004

介绍了分析纺织品来样中织物品种、纱支、密度、组织结构等的步骤和操作方法 ,

关键词：纺织品织物组织织物密度成分

Naturally occurring mutations in the reverse transcriptase region of hepatitis B virus polymerase from treatment-na?ve Korean patients infected with genotype C2

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World Journal of Gastroenterology 2017年第23期23卷 4222-4232页

作者： Ji-Eun Kim So-young Lee hong Kim Ki-Jeong Kim Won-hyeok choe Bum-Joon Kim Department of Biomedical Sciences Microbiology and Immunologyand Liver Research InstituteSeoul National University College of Medicine Department of Microbiology School of MedicineJoong-Ang University Department of Internal Medicine Konkuk University School of Medicine

AIM To report naturally occurring mutations in the reverse transcriptase region(RT) of hepatitis B virus(hBV) polymerase from treatment na?ve Korean chronic patients infected with genotype *** here, full-length hBV reverse transcriptase RT sequences were amplified and sequenced from 131 treatment na?ve Korean patients chronically infected with hepatitis B genotype C2. The patients had two distinct clinical statuses: 59 patients with chronic hepatitis(ch) and 72 patients with hepatocellular carcinoma(hCC). The deduced amino acids(AAs) at42 previously reported potential nucleos(t)ide analog resistance(NAr) mutation positions in the RT region were analyzed. RESULTS Potential NAr mutations involving 24 positions were found in 79 of the 131 patients(60.3%). Notably, AA substitutions at 2 positions(rt184 and rt204) involved in primary drug resistance and at 2 positions(rt80 and rt180) that functioned as secondary/compensatory mutations were detected in 10 patients(1 ch patient and 9 hCC patients) and 7 patients(1 ch and 6 hCC patients), respectively. The overall mutation frequencies in the hCC patients(3.17%, 96/3024 mutations) were significantly higher than the frequencies in the ch patients(2.09%, 52/2478 mutations)(P = 0.003). In addition, a total of 3 NAr positions, rt80, rt139 and rt204 were found to be significantly related to hCC from treatment na?ve Korean patients. CONCLUSION Our data showed that naturally occurring NAr mutations in South Korea might contribute to liver disease progression(particularly hCC generation) in chronic patients with genotype C2 infections.

关键词： hepatitis B virus Polymerase Reverse transcriptase Potential nucleos(t)ide analog resistance chronic hepatitis hepatocellular carcinoma