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Clinical effectiveness of adding probiotics to a low FODMAP diet:Randomized double-blind placebo-controlled study

World Journal of Clinical Cases 2021年第25期9卷 7417-7432页

作者： Beril Turan göksel Bengi Ruksan Cehreli Hale Akpınar Müjde Soytürk Department of Internal Medicine Dokuz Eylül UniversityIzmir 35000Turkey Department of gastroenterology Dokuz Eylul University IzmirIzmir 35000Turkey Department of Preventive Oncology Dokuz Eylül UniversityInstitute of Oncologyİzmir 35000Turkey

BACKgROUND There are various studies showing the relationship between irritable bowel syndrome(IBS)and diet,and some dietary adjustments are recommended to reduce *** recent years,there is a growing number of studies that show a 4-8 wk low fermentable oligo,di-and mono-saccharides and polyols(FODMAP)diet has a 50%-80%significant effect on symptoms in IBS *** is strong evidence suggesting that changes in fecal microbiota have an impact on IBS *** on this argument,probiotics have been used in IBS treatment for a long *** is seen,the FODMAP diet and probiotics are used separately in IBS *** To evaluate the effectiveness of adding probiotics to a low FODMAP diet to control the symptoms in patients with *** The patients who were admitted to the gastroenterology Clinic of Dokuz Eylul University Hospital and diagnosed with IBS according to Rome IV criteria were enrolled into the *** were randomized into 2 groups each of which consisted of 50 *** patients were referred to a dietitian to receive dietary recommendations for the low FODMAP diet with a daily intake of 9 *** patients were asked to keep a diary of foods and beverages they *** patients in group 1 were given supplementary food containing probiotics(2 g)once a day in addition to their low FODMAP diet,while the patients in group 2 were given a placebo once a day in addition to their low FODMAP *** analogue scale(VAS),the Bristol Stool Scale and IBS Symptom Severity Scale(IBSSSS)scores were evaluated before and after the 21 d *** The rate of adherence of 85 patients,who completed the study,to the FODMAP restricted diet was 92%,being 90%in group 1 and 94%in group *** mean scores of VAS and IBS-SSS of the patients in group 1 before treatment were 4.6±2.7 and 310.0±78.4,respectively,and these scores decreased to 2.0±1.9 and 172.0±93.0 after treatment(both Pg

关键词： Irritable bowel syndrome Probiotics Low Fermentable Oligo,Di-and Mono-Saccharides and Polyols diet Visual Analogue Scale the Bristol Stool Scale Irritable Bowel Syndrome Symptom Severity Scale

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《圣大解脱经》的传播情况论析

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中国蒙古学（蒙文） 2021年第3期49卷 99-103页

作者：宝山不详

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Advanced Fiber-Optic Acoustic Sensors

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Photonic Sensors 2014年第3期4卷 198-208页

作者： Joao g. V. TEIXEIRA Ivo T. LEITE Susana SILVA Orlando FRAZAO EQS group Rua Joaquim Dias Rocha 354 4470-221 Maia Portugal lNESC TEC (coordinated by INESC Porto) Rua Campo Alegre 687 4169-007 Porto Portugal Department of Physics and Astronomy Faculty of Sciences- University of Porto Rua Campo Alegre 687 4169-007 Porto Portugal

Acoustic sensing is nowadays a very demanding field which plays an important role in modern society, with applications spanning from structural health monitoring to medical imaging. Fiber-optics can bring many advantages to this field, and fiber-optic acoustic sensors show already performance levels capable of competing with the standard sensors based on piezoelectric transducers. This review presents the recent advances in the field of fiber-optic dynamic strain sensing, particularly for acoustic detection. Three dominant technologies are identified - fiber Bragg gratings, interferometric Mach-Zehnder, and Fabry-Perot configurations - and their recent developments are summarized.

关键词： Acoustic sensors fiber optics optical fiber sensors

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Identification and antioxidant activity of natural functional microstructures produced with various neutral chemicals and bovine serum albumin

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Food Bioscience 2022年第5期49卷 833-841页

作者： Zeynep Ziyade¨Ozacar Atheer Atiro˘glu Vesen Atiro˘glu Nuray güy Mahmut¨Ozacar Sakarya University Science&Arts FacultyDepartment of Chemistry54187SakaryaTurkey Sakarya University BiomedicalMagnetic and Semiconductor Materials Application and Research Center(BIMAS-RC)54187SakaryaTurkey Sakarya University BiomaterialsEnergyPhotocatalysisEnzymeTechnologyNan&Advanced MaterialsAdditive ManufacturingEnvironmental Applications and Sustainability Research&Development Group(BIOENAMS R&D Group)54187SakaryaTurkey

Stress-related conditions are a product of modern practices,and different treatments,such as meditation,yoga,and antistress medications,are utilized to reduce disincentive stress *** medicines are rescued humanity from a variety of illnesses,and they could be able to provide adequate responses to stress-induced *** this article,bovine serum albumin(BSA)microparticles comprising germinated seeds wheat-ginger,germinated seeds wheat-rosemary loaded BSA microparticles(gSW-ROS-MPs),germinated seeds wheat-asafoetida loaded BSA microparticles(gSW-ASA-MPs),ginger-rosemary loaded BSA microparticles(gIN-ROS-MPs),resveratrol-ginger microspheres(RES-gIN-MSs),resveratrol-rosemary microspheres(RES-ROS-MSs),resveratrol-asafoetida microspheres(RES-ASA-MSs),and asafoetida-ginger microspheres(ASA-gIN-MSs)were enhanced to improve the biopharmaceutical features of the neutral *** all MPs kinds synthesized had a so-called spherical morphology,the microspheres were found to be non-porous and with a smooth spherical surface *** antiradical activities were *** activities of RES-ASA-MSs and gIN-ROS-MPs were found to be ***,BSA-containing RES-ASA-MSs and gIN-ROS-MPs can be alternative systems for improving the features of these compounds and administering them therapeutically *** conclusion,all prepared compounds in the present study displayed substantial in vitro free radical-scavenging capability which was dose dependent and be applicate in oxidative stress-based diseases.

关键词： Microstructures Asafoetida Rosemary Resveratrol and ginger

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Visual representation and characterization of three-dimensional hydrofracturing cracks within heterogeneous rock through 3D printing and transparent models

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International Journal of Coal Science & Technology 2016年第3期3卷 284-294页

作者： Peng Liu Yang Ju Pathegama g. Ranjith Zemin Zheng Li Wang Ayai Wanniarachchi School of Mechanics and Civil Engineering ChinaUniversity of Mining & Technology Beijing 100083 China State Key Laboratory of Coal Resources & Safe Mining China University of Mining & Technology Dll XueyuanRoad Beijing 100083 China State Key Laboratory for geomechanics & Deep Underground Engineering China University of Mining &Technology Xuzhou 221116 China Department of Civil Engineering Monash University Clayton Melbourne VIC 3800 Australia

The heterogeneity of unconventional reservoir rock tremendously affects its hydrofracturing behavior. A visual representation and accurate characterization of the three-dimensional （3D） growth and distribution of hydrofracturing cracks within heterogeneous rocks is of particular use to the design and implementation of hydrofracturing stimulation of unconventional reservoirs. However, because of the difficulties involved in visually representing and quantitatively characterizing a 3D hydrofracturing crack-network, this issue remains a challenge. In this paper, a novel method is proposed for physically visualizing and quantitatively characterizing the 3D hydrofracturing crack-network distributed through a heterogeneous structure based on a natural glutenite sample. This method incorporates X-ray microfocus computed tomography （μCT）, 3D printing models and hydrofracturing triaxial tests to represent visually the heterogeneous structure, and the 3D crack growth and distribution within a transparent rock model during hydrofracturing. The coupled effects of material heterogeneity and confining geostress on the 3D crack initiation and propagation were analyzed. The results indicate that the breakdown pressure of a heterogeneous rock model is significantly affected by material heterogeneity and confining geostress. The measured breakdown pressures of heterogeneous models are apparently different from those predicted by traditional theories. This study helps to elucidate the quantitative visualization and characterization of the mechanism and influencing factors that determine the hydrofracturing crack initiation and propagation in heterogeneous reservoir rocks.

关键词： Hydrofracturing cracks Visual representation and characterization Transparentized structures Heterogeneous rock 3D printing Coupled effects of heterogeneity and geostress

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Brazilin from Caesalpinia sappan heartwood and its pharmacological activities:A review

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Asian Pacific Journal of Tropical Medicine 2015年第6期8卷 421-430页

作者： Nilesh P Nirmal Mithun S Rajput Rangabhatla g.S.V.Prasad Mehraj Ahmad Center for Nutrition and Food Sciences Queensland Alliance for Agriculture and Food InnovationUniversity of QueenslandHealth and Food Sciences PrecinctBlock 1039 Kessels RoadCoopers PlainsAcheifield Brisbane QLD 4108Australia Department of Medical Biochemistry.MgM Medical College Biomedical and Pharmaceutical Technology Research group Nano Research for Advanced Materials Institute of Nutrition.Mahidol University 999 Phutthamonthon 4 Rd.SalayaNakhon Pathom-73170Thailand

Caesalpinia sappan L.(CS) is a plant of Leguminosae family,commonly known as Brazil or Sappan *** is distributed in Southeast Asia and its dried heartwood has been used as traditional ingredient of food or beverages and has a wide variety of medicinal *** extraction yield of CS wood was achieved with 95% ethanol for 2 *** constituent's investigation of sappan wood resulled in the isolation of various structural types of phenolic components including one xanihone,one coumarin,three chalcones,two flavones three homoisoflavonoids and ***[(6a S-cis)-7,11b-dihydrobcnz[b]indeno[1.2-d]pyran-3.6a.9.10(6H)- tetroll.a major and active compound found in CS *** of the folkloric uses of brazilin were validated by the scientific studies such as antioxidant,antibacterial,anti-inflammatory,***,vasorelaxant,hepatoproteetive and anti-acne *** heartwood extract is safe and did not produce any acute or subacute toxicity in both male and female *** is the safe natural compound having potential to develop as a medicinal compound with application in food,beverage,cosmetics and pharmaceutical industries to screen its clinical use in modern *** information gained could provide the important and potential approach for pharmaceutical researcher to implicate the knowledge of brazilin in the formulation of new drug and to reveal therapeutic and gaps requiring future research *** studies are needed to evaluate the potential application of brazilin as preservative and coloring agent in food processing industries.

关键词： Brazilin Caesalpinia sappan Extraction Heartwood Pharamcological activities

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Quantitative Determination of Density of ground State Atomic Oxygen from Both TALIF and Emission Spectroscopy in Hot Air Plasma generated by Microwave Resonant Cavity

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Plasma Science and Technology 2016年第3期18卷 259-265页

作者： F.MARchAL M.YOUSFI N.MERBAHI g.WATTIEAUX A.PIQUEMAL University of Toulouse UPSLAPLACE CNRS UMR 5213 CEA DAMDIF

Two experimental techniques have been used to quantify the atomic oxygen density in the case of hot air plasma generated by a microwave （MW） resonant cavity. The latter operates at a frequency of 2.45 gHz inside a cell of gas conditioning at a pressure of 600 mbar, an injected air flow of 12 L/min and an input MW power of 1 kW. The first technique is based on the standard two photon absorption laser induced fluorescence （TALIF） using xenon for calibration but applied for the first time in the present post discharge hot air plasma column having a temperature of about 4500 K near the axis of the nozzle. The second diagnostic technique is an actinometry method based on optical emission spectroscopy （OES）. In this case, we compared the spectra intensities of a specific atomic oxygen line （844 nm） and the closest wavelength xenon line （823 nm）. The two lines need to be collected under absolutely the same spectroscopic parameters. The xenon emission is due to the addition of a small proportion of xenon （1% Xe） of this chemically inert gas inside the air while a further small quantity of H2 （2~） is also added in the mixture in order to collect OH（A- X） and NH（A-X） spectra without noise. The latter molecular spectra are required to estimate gas and excitation temperatures. Optical emission spectroscopy measurements, at for instance the position z=12 mm on the axis plasma column that leads to a gas measured temperature equal to 3500 K, an excitation temperature of about 9500 K and an atomic oxygen density 2.09× 1017＋ 0.2×1017 cm-3. This is in very good agreement with the TALIF measurement, which is equal to 2.0×101T cm-3.

关键词： TALIF microwave air plasma atomic oxygen concentration actinometry,optical emission spectroscopy

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Hepatobiliary manifestations in inflammatory bowel disease: The gut,the drugs and the liver

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World Journal of gastroenterology 2013年第42期19卷 7327-7340页

作者： María Rojas-Feria Manuel Castro Emilio Suárez Javier Ampuero Manuel Romero-gómez Unit for Medical and Surgical Management of Digestive Diseases and CIBERehd Valme University HospitalUniversity of SevilleE-41014 SevillaSpain

Abnormal liver biochemical tests are present in up to30%of patients with inflammatory bowel disease(IBD),and therefore become a diagnostic *** and biliary tract diseases are common extraintestinal manifestations for both Crohn’s disease and ulcerative colitis(UC),and typically do not correlate with intestinal *** sclerosing cholangitis(PSC)is the most common hepatobiliary manifestation of IBD,and is more prevalent in *** 5%of patients with UC develop PSC,with the prevalence reaching up to 90%.cholangiocarcinoma and colon cancer risks are increased in these *** common disorders include autoimmune hepatitis/PSC overlap syndrome,Igg4-associated cholangiopathy,primary biliary cirrhosis,hepatic amyloidosis,granulomatous hepatitis,cholelithiasis,portal vein thrombosis,liver abscess,and non-alcoholic fatty liver *** B reactivation during immunosuppressive therapy is a major concern,with screening and vaccination being recommended in serologically negative cases for patients with *** prophylaxis with entecavir or tenofovir for 6to 12 mo after the end of immunosuppressive therapy is mandatory in patients showing as hepatitis B surface antigen(HBsAg)positive,independently from viral *** negative and anti-HBc positive patients,with or without anti-HBs,should be closely monitored,measuring alanine aminotransferase and hepatitis B virus DNA within 12 mo after the end of therapy,and should be treated if the viral load *** the other hand,immunosuppressive therapy does not seem to promote reactivation of hepatitis C,and hepatitis C antiviral treatment does not influence IBD natural history *** of the drugs used for IBD treatment may induce hepatotoxicity,although the incidence of serious adverse events is *** in liver biochemical tests associated with aminosalicylates are uncommon and are usually not clinically *** hepatotoxicity has been describ

关键词： Inflammatory bowel disease Hepatobiliary disorders Extraintestinal manifestations Primary sclerosing cholangitis Drug-induced liver injury Hepatotoxicity Hepatitis B Hepatitis C

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changes in the redox status of the brain in an experimental glaucoma model

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BIOCELL 2016年第1期40卷 51-53页

作者： CLAUDIA g.REIDES ROMINA M.LASAgNI VITAR AgUSTINA PEVERINI NATASHA S.JANEZIC AILEN g.HVOZDA ARANA SANDRA M.FERREIRA SUSANA F.LLESUY Química general e Inorgánica Facultad de Farmacia y Bioquímica.Universidad de Buenos AiresBuenos Aires Argentina Instituto de Bioquímica y Medicina Molecular(IBIMOL) Universidad de Buenos Aires-CONICETBuenos AiresArgentina

The purpose of this study was to evaluate the redox status changes of primary visual targets in the rat brain of a high pressure-induced glaucoma *** animal model consisted of inducing ocular hypertension by cauterizing two episcleral veins on the left *** markers of oxidative damage and the oxidative balance evaluated in the brain seven days postoperative were:nitrites concentration,levels of non-enzymatic antioxidants and antiox-idant enzymes *** increase in the nitrite content,which could be the result of the enhancement in the production of nitrogen species,and in the activity of NADPH oxidase in the glaucoma group could lead to an increase on lipid and protein *** decrease on the non-enzymatic antioxidants and the compensatory increase of the superoxide dismutase and glutathione peroxidase activities could be a consequence of the increase of oxidative *** decrease in the activity of glutathione reductase leads to a decrease in the recycling of thiol *** suggest that oxidative stress can possibly acts as a risk factor for neurodegeneration in the ***-tic strategies to stop the progression of the disease in glaucoma should also be considered the central neuronal degeneration beyond the retina and the optic nerve.

关键词： oxidative damage antioxidants central nervous system neurodegenerative diseases

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基于蒂布特模型的我国公共保障性住房有效供给研究

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乐山师范学院学报 2016年第2期31卷 94-98页

作者：苟兴朝乐山师范学院经济与管理学院四川乐山614000

从总体上看,近年来我国公共保障性住房供给效率偏低。具体表现在:地方政府积极性不高、供给总量不足和结构不合理、保障群体满意度较低等。蒂布特模型提供了一个分析地方公共产品有效供给的独特视角,对于当前我国发展住房保障事业具有... 详细信息

从总体上看,近年来我国公共保障性住房供给效率偏低。具体表现在:地方政府积极性不高、供给总量不足和结构不合理、保障群体满意度较低等。蒂布特模型提供了一个分析地方公共产品有效供给的独特视角,对于当前我国发展住房保障事业具有较大的指导作用。

关键词：蒂布特模型公共保障性住房地方公共产品有效供给

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