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Cellular & Molecular Immunology 2020年第6期17卷 631-646页

作者： Xiaoyu Sun Tianheng Hou Edwin ch.ung Tiffany Nga-Teng Iu Victor wai-Hou Tam Ida Miu-Ting ch. Miranda Sin-Man Tsang Paul Kay-Sheung ch.n ch.istopher wai-Kei Lam ch.n-Kwok Wong Department of ch.mical Pathology The Chinese University of Hong KongHong KongChina Cancer Centre/Centre of Precision Medicine Research.and Training Faculty of Health SciencesUniversity of MacaoMacaoChina Institute of ch.nese Medicine and State Key Laboratory of Research.on Bioactivities and Clinical Applications of Medicinal Plants The Chinese University of Hong KongHong KongChina Department of Microbiology The Chinese University of Hong KongHong KongChina Faculty of Medicine and State Key Laboratory of Quality Research.in ch.nese Medicines Macao University of Science and TechnologyMacaoChina Li Dak Sum yip Yio ch.n R&D Centre for ch.nese Medicine The Chinese University of Hong KongHong KongChina

We elucidated the anti-inflammatory mech.nisms of IL-38 in allergic *** bronch.al epithelial cells and eosinophils were cocultured upon stimulation with the viral RLR ligand poly(I:C)/LyoVec or infection-related cytokine TNF-αto induce expression of cytokines/ch.mokines/adhesion *** dust mite(HDM)-induced allergic asthma and humanized allergic asthma NOD/SCID murine models were established to assess anti-inflammatory mech.nisms in ***-38 significantly inhibited induced proinflammatory IL-6,IL-1β,CCL5,and CXCL10 production,and antiviral interferon-βand intercellular adhesion molecule-1 expression in the coculture *** cytometry and RNA-sequencing analysis revealed that IL-38 could antagonize the activation of the intracellular STAT1,STAT3,p38 MAPK,ERK1/2,and NF-κB pathways,and upregulate the expression of the host defense-related gene POU2AF1 and anti-allergic response gene *** injection of IL-38 into HDM-induced allergic asthma mice could ameliorate airway hyperreactivity by decreasing the accumulation of eosinophils in the lungs and inhibiting the expression of the Th2-related cytokines IL-4,IL-5,and IL-13 in the bronch.alveolar lavage fluid(BALF)and lung *** examination indicated lung inflammation was alleviated by reductions in cell infiltration and goblet cell hyperplasia,together with reduced Th2,Th17,and innate lymphoid type 2 cell numbers but increased proportions of regulatory T cells in the lungs,spleen,and lymph ***-38 administration suppressed airway hyperreactivity and asthma-related IL-4 and IL-5 expression in humanized mice,together with significantly decreased CCR3^(+) eosinophil numbers in the BALF and lungs,and a reduced percentage of human CD4^(+)CRTH2^(+)Th2 cells in the lungs and mediastinal lymph ***,our results demonstrated the anti-inflammatory mech.nisms of IL-38 and provided a basis for the development of a regulatory cytokine-based treatment for allergic

关键词： allergic asthma eosinophils IL-38 ILC2s Tregs

Effect of Tai ch. ch.an on serotonin and cortisol for monitoring stress and quality of life in post-treatment breast cancer patients

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中华乳腺病杂志（电子版） 2014年第4期8卷 34-40页

作者： William wai Nam Tsang Wings Tjing Yung Loo Louis Wing ch.ong ch.w Elizabeth Lam Yan Ng Adrian Yun San yip Jianping ch.n Department of Rehabilitation Sciences Hong Kong Polytechnic University UNIMED Medical Institute and Organisation for Oncology and Translational Research Sch.ol of ch.nese Medicine Li Ka Shing Faculty of MedicineUniversity of Hong Kong

Objective Immediate physical exercise has been recommended for patients in the recovery phase to improve survival and quality of life(QOL)and reduce recurrence of *** new NCCN Guidelines for Survivorship also highlighted the role of exercise in post-cancer health,encouraging patients to perform light physical activity following *** aim of our study is to effect of Tai ch. ch.an(TCC)on serotonin and cortisol for monitoring stress and QOL in post-treatment breast cancer *** Totally85 post-treatment breast cancer patients were enrolled in this study to observe the effects of practicing TCC on recovery,as well as stress and happiness which.are indicators of QOL of in *** blood was drawn from study subjects to analyze the levels of serotonin,cortisol and high sensitive C-reactive protein(HSCRP)at baseline,and at 3,6 and 12 months of TCC *** was drawn from healthy subjects only at baseline.A QOL questionnaire was administered to study subjects at three time points throughout the study,and once for healthy *** data were processed by analysis of variance of repeated *** At 3,6 and 12 months time points following regular TCC exercise,WBC,RBC,hemoglobin in blood samples showed a statistically significant difference(F=161.55,172.14,289.73;all P=0.00);the level of serotonin(biomarker for well-being),cortisol(indicator of stress)and HS-CRP(biomarker for inflammation)showed a statistical improvement(F=307.46,182.85,102.23;all P=0.00).After 3,6 and 12 months of regular TCC exercise,according to the results of QOL questionnaire,the indicators including quality of sleep,perceived hunger,fatigue,contentment,stress and social interaction presented a significant difference(F=312.98,222.64,543.90,46.05,28.10,78.92,all P<0.05),while there was no statistical difference in life dissatisfaction(F=56.61,P=0.166)Conclusions TCC physical activity for post-treatment breast cancer patients improved QOL and overall

关键词：乳腺病患者临床分析治疗方法

Outcomes of emergency and interval hepatectomy for ruptured resectable hepatocellular carcinoma: a single tertiary referral centre experience

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Hepatoma Research 2017年第9期3卷 196-204页

作者： Andrew Kai yip Fung ch.ring ch.ng Ning ch.ng Kit Fai Lee John Wong Yue Sun ch.ung Anthony Kwong wai Fong Paul Bo San Lai Department of Surgery the Chinese University of Hong KongPrince of Wales HospitalHong Kong 999077Hong KongChina

Aim: The short and long term outcomes of patients who underwent emergency and interval hepatectomy for ruptured and resectable hepatocellular carcinoma (HCC) were analysed. Methods: The data of patients with ruptured HCC presenting between April 2004 and October 2015 were analysed. Emergency hepatectomy was defined as hepatectomy within 48 h of the clinico-radiological diagnosis of HCC rupture. Results: Thirty patients underwent hepatectomy for ruptured HCC. Nine (30%) patients underwent emergency hepatectomy. The median age was 56 and 54 years (P = 0.13) with a similar gender distribution. The mean HCC size (10.5 vs. 8.3 cm, P = 0.17), total blood loss (3,000 vs. 850 mL, P = 0.002) and total units of red blood cell transfusion (1.9 vs. 0.5 units, P = 0.27) were greater in the emergency hepatectomy group. The complication rate was 44% and 38% (P = 0.53), with median length of hospital stay of 10 and 12 days (P = 0.07) in the emergency and interval hepatectomy groups, respectively, and no 30-day mortality in both groups. The median overall survival was 29 and 15.7 months (P = 0.25), with survival rates of 78%, 45%, 0% and 85%, 43% and 5% at 1, 3 and 5 years in the emergency and interval hepatectomy groups, respectively. Conclusion: Hepatectomy should be considered for ruptured HCC provided the patient could tolerate curative resection.

关键词： Hepatocellular carcinoma rupture hepatectomy

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遥远与贴近：翻译庞德的一些理论问题

华文文学 2011年第3期 17-28页

作者：叶维廉[美国] 美国加州大学圣地亚哥校区比较文学系

本文试图凸显近年翻译庞德《诗章》所经验的一些理论问题。《诗章》里涌溢着一层又一层的神话,不同的文化,历史,一时不知如何去将之驯服,或者不应该将之驯服,这些层次传意的交织网是如此的复杂,仿佛无法在中国文化意符网络里找到比对的... 详细信息

本文试图凸显近年翻译庞德《诗章》所经验的一些理论问题。《诗章》里涌溢着一层又一层的神话,不同的文化,历史,一时不知如何去将之驯服,或者不应该将之驯服,这些层次传意的交织网是如此的复杂,仿佛无法在中国文化意符网络里找到比对的表意策略。还有一个意想不到的问题,庞德在英文文本里加插了很多中文字,在英文的文本里,中文字是一个异质的符号,有待解释的符号,是现代诗里的一种"异化"的效果,是一种先惊后觉的效果,但他们在翻译成中文的文本里语锋便完全失去。此外,《诗章》全长800页,注解800余页,这也都是我却步的原因。

关键词：遥远贴近翻译庞德《诗章》

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史蒂文斯诗中的“物自性”

华文文学 2011年第3期 7-16页

作者：叶维廉[美国] 美国加州大学圣地亚哥校区比较文学系

"道家美学"讲求任万物不受干预地、不受侵扰地自然自化的兴现,其含义是肯定物之为物的本然本样,肯定物的自性。美国在哲学、美学方面从超越到"物自性"的转变是复杂而多线的。追寻史蒂文斯诗里的蜕变,可以发现史蒂文斯是显著的"没有信仰... 详细信息

"道家美学"讲求任万物不受干预地、不受侵扰地自然自化的兴现,其含义是肯定物之为物的本然本样,肯定物的自性。美国在哲学、美学方面从超越到"物自性"的转变是复杂而多线的。追寻史蒂文斯诗里的蜕变,可以发现史蒂文斯是显著的"没有信仰的诗人",他大部分的诗,都是一种有关信仰的冥思和新的存在理由的寻索,仿佛是一首庞大的"论诗艺"的诗,寻索和肯定地面上的世界,肯定物之为物自身具足这个事实。

关键词：史蒂文斯诗歌物自性道家美学

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建初銅尺的考訂與詩乾嘉考訂家的物緣與詩情

中国文化 2020年第2期 340-349页

作者：葉倬瑋香港教育大學文學文化學系中國文學文化研究中心

孔尚任發現西漢建初銅尺後,將之帶返闕里,撰文三篇以志念。乾嘉時期,建初銅尺成爲周漢古制考訂者趨之若鶩的珍品,翁方綱、阮元、黄文暘等人都撰寫過考訂詩和文章。梳理這些故事,探尋詩歌寫作的前因,明瞭作者在文本中對人與物相遇的觸動... 详细信息

孔尚任發現西漢建初銅尺後,將之帶返闕里,撰文三篇以志念。乾嘉時期,建初銅尺成爲周漢古制考訂者趨之若鶩的珍品,翁方綱、阮元、黄文暘等人都撰寫過考訂詩和文章。梳理這些故事,探尋詩歌寫作的前因,明瞭作者在文本中對人與物相遇的觸動,將能在批評考訂詩的聲音以外,理解這些詩歌寄寓的物緣和情感。

关键词：建初尺考訂詩翁方綱物缘

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一件南明烈士遺物的流轉

中国文化 2019年第1期 152-165页

作者：葉倬瑋香港教育大學文學及文化學系

乾隆名臣王昶在雅集時端出明末義士鄺露的硯臺,引發了許多考訂詩的創作。當時正是鄺露詩集遭到禁燬的時代,這些考訂詩改變了鄺露作爲節義符號的結構,寄寓了詩人的哀憫與共感。乾嘉之時出現了以考訂爲詩的風氣,曾被認爲是詩道之一厄。假... 详细信息

乾隆名臣王昶在雅集時端出明末義士鄺露的硯臺,引發了許多考訂詩的創作。當時正是鄺露詩集遭到禁燬的時代,這些考訂詩改變了鄺露作爲節義符號的結構,寄寓了詩人的哀憫與共感。乾嘉之時出現了以考訂爲詩的風氣,曾被認爲是詩道之一厄。假若能走進詩歌的歷史語境,當能對文學如何被需要、什麽樣的文學才能被需要,有更真切的體會。

关键词：考訂詩鄺露王昶翁方綱雅集

Analysis of an Unconditionally Stable Explicit Finite-difference Time-domain Method

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Analysis of an Unconditionally Stable Explicit Finite-differ...

实时三维超声心动图评价左心室容积的临床应用：与二维超声心动图的对比研究

2002海峡两岸三地无线科技研讨会

作者： Man-kin Sun, wai-yip Tam Department of Electronic and Information Engineering, The Hong Kong Polytech.ic University, Hung Hom, Kowloon, Hong Kong, ch.na

In this paper, an unconditionally stable explicit finite-difference time-domain (FDTD) method is proposed. The method is derived by applying the Durfort-Frankel method to approximate the spatial deri

关键词： FDTD stability numerical dispersion

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中华超声影像学杂志 2008年第2期17卷 100-103页

作者：李春梅房芳桑清张庆王梅 ch.uk-Man Yu Gabriel wai-Kwok yip 四川省人民医院超声医学中心成都610072 香港中文大学威尔斯亲王医院心脏中心

目的评价实时三维超声心动图（RT-3DE）测量成人左室容积和射血分数（EF）的可行性，探讨RT-3DE与二维超声心动图（2DE）测量成人左室容积和EF的相关性。方法选择健康及各类心脏疾病患者210例，用双平面Simpson法获得左室舒张末容积（... 详细信息

目的评价实时三维超声心动图（RT-3DE）测量成人左室容积和射血分数（EF）的可行性，探讨RT-3DE与二维超声心动图（2DE）测量成人左室容积和EF的相关性。方法选择健康及各类心脏疾病患者210例，用双平面Simpson法获得左室舒张末容积（EDV）、收缩末容积（ESV）和EF；于心尖四腔观获得左室“金字塔”形全容积三维数据库，脱机用Qlab分析软件，半自动分析获得EDV、ESV及EF值。对比分析两种方法测算左室容积和EF值的相关性。结果所有受检者的左室RT-3DE图像均成功获取和分析，每位受检者RT-3DE和2DE图像获取和分析所需时间平均为（6±2）min和（5±1）min，图像质量好、良、差分别为70％与72％、23％与20％、6％与8％。2DE和RT-3DE获得的左室容积有明显的相关性，EDV分别为（81±31）ml，（85±35）ml，r=0．91，P〈0．001；ESV分别为（32±22）ml，（35±25）ml，r＝0.93,P＜0.001;ET分别为（63±11）％，（61±10）％，r=0．81，P〈0．001。结论 RT-3DE检测左室容积和功能简便、快捷、易行，对不同的心血管疾病，RT-3DE和2DE测算的容积和心功能有明显的相关性。

关键词：超声心动描记术实时三维心室功能左