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Dynamic Modelling of Dengue Epidemics in Function of Available Enthalpy and Rainfall

Open Journal of Epidemiology 2016年第1期6卷 50-79页

作者： Hugo Abi Karam Julio cesar Barreto da Silva Augusto José Pereira Filho José Luis flores Rojas Instituto de Geociências IGEO-CCMN-UFRJ Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil Departmento de Estatística CCET-UFRN Universidade Federal do Rio Grande do Norte Natal Brasil Instituto de Astronomia Geofísica e Ciências Atmosféricas IAG-USP Universidade de Sao Paulo SP Brasil

In this work, we present results of an investigation of environmental precursors of infectious epidemic of dengue fever in the Metropolitan Area of Rio de Janeiro, RJ, Brazil, obtained by a numerical model with representation of infection and reinfection of the population. The period considered extend between 2000 and 2011, in which it was possible to pair meteorological data and the reporting of dengue patients worsening. These data should also be considered in the numerical model, by assimilation, to obtain simulations of Dengue epidemics. The model contains compartments for the human population, for the vector Aedes aegypti and four virus serotypes. The results provide consistent evidence that worsening infection and disease outbreaks are due to the occurrence of environmental precursors, as the dynamics of the accumulation of water in the breeding and energy availability in the form of metabolic activation enthalpy during pre-epidemic periods.

关键词： Modelling Dengue Epidemics Environmental Enthalpy Environmental Precursors of Dengue Epidemics

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Fructans from Agave enhance probiotic yoghurt by modulating gut microbiota on children with overweight or obesity

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Food Bioscience 2022年第2期46卷 164-172页

作者： Marco U.Martinez-Martinez Daniel V´azquez-Maldonado Stefan Ratering cesar Godínez-Hern´andez Rosa Isela Ortiz-Basurto Ruth ESoria-Guerra Bellinda Schneider Bertha I.Ju´arez-flores Diana P.Portales-P´erez Sylvia Schnell Fidel Martinez-Gutierrez Posgrado en Ciencias Farmacobiologicas Universidad Autonoma de San Luis PotosiMexico Institute of Applied Microbiology Justus Liebig University Giessen Germany(3)Instituto de Zonas Deserticas Universidad Autonoma de San Luis PotosiMexico Instituto de Investigaci´on de Zonas Des´erticas Universidad Aut´onoma de San Luis PotosíMexico Laboratorio Integral de Investigaci´on en Alimentos Tecnol´ogico Nacional de Mexico/Instituto Tecnol´ogico de TepicNayaritMexico Centro de Investigaci´on en Ciencias de la Salud y Biomedicina Universidad Aut´onoma de San Luis PotosíMexico

Overweight and obesity in children are an increasing public health problem,and the influence the gut microbiota has on it,is still *** consumption of prebiotics has been studied in children with overweight and obesity after an intervention with fermented milk,supplemented with different fructans like prebiotics,was carried out to obtain a healthy *** were randomly assigned into three groups,a double-blind intervention was carried out,receiving different fermented milk products for 6 weeks,including the following supplements:Lactobacillus casei strain Shirota,*** strain Shirota with inulin or *** strain Shirota with fructans from Agave salmiana Otto ex *** was extracted from stool samples and the differential abundance of ASV was monitored by high throughput 16S rRNA gene sequencing.A synbiotic with fructans from *** stimulated the abundance and diversity of the microbiota,specifically on genera Faecalibacterium and Holdemanella,thus,leading to a healthier gut microbiota,which led to obtaining the best anthropometric changes in synbiotic *** intervention may provide health benefits to children with overweight or obesity by increasing the richness of the gut microbiota and stimulate beneficial ***,more studies are needed to get a better understanding of the mechanisms of action.

关键词： Beta diversity Gut microbiota Mexico Prebiotic Probiotic

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种禽管理以获得最佳生产性能

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国外畜牧学（猪与禽） 2017年第12期37卷 11-13页

作者：赵金萍(译) 楼平儿(校) 陈建康(审) 何闪(制图表) cesar coto 不详 Cobb-Vantress

在20世纪90年代早期,Cobb公司就开始收集全球的种禽信息,从那时开始,一种可以提高种禽生产性能的明确模式随之形成。遗传选择对这一进步毫无疑问功不可没,然而对家禽营养和饲养管理需求的更好理解也起着一定的作用。

关键词：生产性能家禽营养遗传选择饲养管理雏鸡种鸡群母鸡遗传潜力限饲生产阶段

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Aortic valve stenosis provides complementary information to bleeding risk scores in non-valvular atrial fibrillation patients initiating anticoagulation

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Journal of Geriatric Cardiology 2020年第3期17卷 141-148,I0005-I0007页

作者： Gines Elvira-Ruiz cesar Caro-Martinez Pedro Joseflores-Blanco Juan JoseCerezo-Manchado Helena Albendin-Iglesias Alejandro Lova-Navarro Francisco Arregui-Montoya Francisca Maria Munoz-Franco Natalia Garcia-Iniesta Arcadio Garcia-Alberola JoseLuis Bailen-Lorenzo Domingo Andres Pascual-Figal Sergio Manzano-Fernández Department of Cardiology University Hospital Virgen de la ArrixacaMurciaSpain Instituto Murciano de Investigación en Biomedicina(IMIB) MurciaSpain Department of Cardiology University Hospital Morales MeseguerMurciaSpain Department of Hematology University Hospital Virgen de la ArrixacaMurciaSpain Department of Internal Medicine University Hospital Virgen de la ArrixacaMurciaSpain School of Medicine University of MurciaMurciaSpain Department of Cardiology Hospital Vega BajaAlicanteSpain

Background The identification of modifiable bleeding risk factors may be of *** aim is to evaluate if aortic stenosis(AS)provides additional information to bleeding risk scores for predicting major bleeding(MB)in non-valvular atrial fibrillation(AF).Methods We designed a retrospective multi-center study including 2880 consecutive non-valvular AF patients initiating oral anticoagulation between January 2013 and December *** was defined as moderate or severe according to European echocardiography guidelines ***,ATRIA and ORBIT scores were used to evaluate the bleeding *** was defined according to the International Society on Thrombosis and Haemostasia criteria and registered at 18 months of *** 168(5.8%)patients had *** with AS had higher risk for MB compared to those without AS(HR=2.13,95%CI:1.40-3.23,P<0.001).Patients without AS and low-intermediate bleeding risk(0 points)showed the lowest MB rate,whereas the MB rate observed among patients with AS and high bleeding risk(2 points)was the highest *** and reclassification analyses showed that AS provided additional information to bleeding risk scores for predicting MB at 18 months of *** In this population,AS was associated with an increased risk for MB at midterm *** three scoring systems showed a moderate discriminatory ability for ***,the addition of AS was associated with a significant improvement in their predictive *** suggest that the presence of this valvulopathy should be taken into account for bleeding risk assessment.

关键词： Anticoagulants Aortic stenosis Atrial fibrillation Major bleeding Valvular disease

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