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Some Aspects of L_(w_1)~r(G) ∩ L(p,q,w_2dμ)(G)

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Chinese Annals of Mathematics,Series B 2009年第3期30卷 311-320页

作者： lker ERYILMAZ cenap DUYAR Department of Mathematics Sciences and Arts FacultyOndokuz Mayis University

Let G be a locally compact Abelian group with Haar *** authors discuss some basic properties of L_(w_1)~r(G) ∩ L(p,q,w_2dμ)(G) *** the necessary conditions for compact embeddings of the spaces L_(w_1)~r(R^d)∩L(p,q,... 详细信息

关键词： Weighted Lebesgue spaces Weighted Lorentz spaces Compact embeddings

Unmasking metabolic dependencies in pancreatic cancer: aberrant polyamine synthesis as a promising new therapeutic target

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Signal Transduction and Targeted Therapy 2023年第11期8卷 5151-5152页

作者： Gerrit Wolters-Eisfeld Thilo Hackert cenap Güngör Department of General Visceral and Thoracic SurgeryUniversity Medical Center Hamburg-EppendorfHamburgGermany

In a recently published Nature article,Lee et *** distinct metabolic dependencies of pancreatic ductal adenocarcinoma(PDA)cells compared to normal tissue,and discovered that PDA cells exhibited a unique reliance on de novo ornithine synthesis from glutamine,rather than *** aberrant polyamine synthesis offers a promising therapeutic target for pancreatic cancer.

关键词： synthesis den depen

Extensive hepatic-portal and mesenteric venous gas due to sigmoid diverticulitis

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World Journal of Gastroenterology 2009年第7期15卷 879-881页

作者： Meral Sen Ayhan Akpinar Aydin Snan Mete Sisman cenap Dener Kayihan Akin Fatih University School of Medicine General Surgery Department06510 AnkaraTurkey Fatih University School of Medicine Radiology Department06510 AnkaraTurkey

Hepatic portal venous gas is most often associated with extensive bowel necrosis due to mesenteric *** exceeds 75% with this *** most common precipitating factors include ischemia,intra-abdominal abscesses and inflammatory bowel *** this report,we present a 75-year-old woman with extensive hepatic portal and mesenteric venous gas due to colonic *** had a 10-year history of type diabetes mellitus and *** was treated by sigmoid resection and Hartmann's procedure and discharged from the hospital without any complications.

关键词： Hepatic portal vein Gas Sigmoid diverticulitis Computed tomography

Effect of FFP2/N95 facemask wear on retinal and choroidal thickness profile in healthy subjects

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International Journal of Ophthalmology(English edition) 2022年第11期15卷 1821-1828页

作者： Betul Onal Gunay Irfan Akalin Ahmet Kalkisim cenap Mahmut Esenulku Elif Betul Turkoglu Department of Ophthalmology University of Health SciencesTrabzon Kanuni Training and Research HospitalTrabzon 61040Turkey Department of Ophthalmology Akdeniz University HospitalAntalya 07070Turkey

AIM: To investigate the influence of non-oil 95(N95)/filtering facepiece 2(FFP2) facemask wear on retinal thickness, choroidal thickness(CT), retinal nerve fiber layer thickness(RNFLT), and ganglion cell layer thickness(GCLT) in healthy ***: In this prospective study, 53 healthy participants who used FFP2/N95 facemask were enrolled. Participants underwent optical coherence tomography imaging before and at 1 and 4h following FFP2/N95 facemask wear. The last imaging session was performed 1h after FFP2/N95 removal. Retinal thickness, CT, RNFLT, and GCLT were assessed at each session. Vital parameters were also assessed. RESULTS: The pulse rate of the subjects significantly decreased at 1 and 4h compared to baseline values(P<0.05). No significant changes in retinal thickness, RNFLT, and GCLT were observed in the study. CT profile showed a significant increase at all measured locations except 1-mm temporal, 1-mm inferior and 2-mm inferior points following FFP2/N95 wear which turned to baseline values after FFP2/N95 removal. Pulse rate and CT changes at 4h were significantly correlated(P<0.05).CONCLUSION: Parasympathetic activation during FFP2/N95 facemask wear might have a role on elevated CT measurements in healthy individuals by virtue of increased choroidal blood flow.

关键词： choroid ganglion cell layer FFP2/N95 facemask retina retinal nerve fiber layer thickness

Histologic examination of the clipped internal thoracic artery by transmission electron microscope in patients undergoing coronary artery bypass grafting

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World Journal of Cardiovascular Diseases 2012年第3期2卷 208-212页

作者： cenap Ozkara Department of the Cardiovascular Surgery Corlu Sifa Hospital Tekirdag Turkey

Object?ves: As we known that the internal thoracic artery (ITA) has an excellent patency rate in coronary artery bypass grafting (CABG). However, early graft failure due to occlusion and spasm is still the major problem after coronary artery bypass surgery. We examined histopathologic findings of the clipped internal thoracic artery (ITA) in patients undergoing CABG using transmission electron microscope (TEM). Methods: To investigate the histopathololojic ITA examination, 60 patients were randomly selected. The ITA was harvested in a standart fashion with the use of low voltage electrocotery and its distal end was cut prior to bifurcation and clipped. Just before the ITA anastomosis 1 mm lenght of ITA ring was cut and saved in 2.5% Glutaraldehide solution for fixation and examination of transmission electron microscope (TEM). One blinded anatomopatholog examined all specimens and described the endothelial integrity according to the score system proposed by Fischlein et al. Results: In ten cases (17.5%) different degree of histopathologic findings (endothelial cells, intercellular and intracellular organels and adventitia) were recorded The most important histopatholojic findings of ITA were as follows: endothelial vacuolisation, intimal thickening and/or intimal seperation, suben-dothelial edema, swallowing of cytoplasma and mito-condria. Conclusion: Our results showed that the endothelial pathology is high when the ITA clipped. Unfortunataly, because our study did not include the non-clipped ITA we have not concluded the comparison or statistical results. In our opinion, for absolute definition of the effects of the clipping the ITA it should be planned the comparative results between the clipped and non-clipped ITA histologic examinations.

关键词： Internal Thoracic Artery ITA Clipping Endothelia Pathology

A meta-analysis of 1-year outcomes of transcatheter versus surgical aortic valve replacement in low-risk patients with severe aortic stenosis

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Journal of Geriatric Cardiology 2020年第1期17卷 43-50,I0008-I0010页

作者： Aaqib H Malik Syed Zaid Hasan Ahmad Joshua Goldberg Tanya Dutta cenap Undemir Martin Cohen Wilbert S Aronow Steven L Lansman Department of Medicine Westchester Medical Center and New York Medical CollegeValhallaNYUSA Department of Cardiology Westchester Medical Center and New York Medical CollegeValhallaNYUSA Section of Cardiothoracic Surgery Department of SurgeryWestchester Medical CenterValhallaNew YorkUSA

Background Transcatheter aortic valve replacement(TAVR)for the treatment symptomatic severe aortic stenosis(AS)is indicated in patients with intermediate or higher surgical *** trials showed TAVR,and surgical aortic valve replacement(SAVR)perform similarly at 1-year for the composite outcomes of mortality,stroke and *** performed a comprehensive meta-analysis to compare individual outcomes at 1-year for TAVR compared to SAVR in low-risk *** Pub Med,Embase,and Cochrane central were searched for all the randomized controlled trials(RCTs)that reported 1-year comparative outcomes of TAVR and surgical aortic valve replacement(SAVR).Our conclusions are based upon the random-effects model using Der Simonian-Laird *** Data from 4 trials and 2887 randomized patients showed that TAVR had lower rates of all-cause mortality,cardiovascular mortality,and atrial fibrillation compared to SAVR at 1-year follow-up(P<0.05 for all).Also,TAVR was also associated with a significantly higher risk of permanent pacemaker implantation and moderate-severe paravalvular leak(P<0.05).Conclusions The latest randomised trial data demonstrates that in short-term,TAVR is safe and effective in reducing all-cause mortality or *** follow-up of RCTs is needed to determine the durability of clinical benefits in TAVR over SAVR in low-risk patients.

关键词： Aortic stenosis Low surgical risk Meta-analysis Transcatheter aortic valve replacement

Effect of topical vasodilator on internal thoracic artery blood flow. A placebo-controlled clinical study

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World Journal of Cardiovascular Diseases 2012年第3期2卷 204-207页

作者： cenap Ozkara Omer Faruk Dogan Cevdet Furat Department of Cardiovascular Surgery Corlu Sifa HospitalIstanbulTurkey Department of Cardiovascular Surgery Adana Numune Education and Training HospitalAdanaTurkey Zonguldak Eregli Devlet Hastanesi ZonguldakTurkey

Objective: The internal thoracic artery (ITA) is the conduit of choice for coronary artery bypass grafting (CABG). To avoid spasm of the ITA various topical vasodilators have been suggested either intraluminally or by topical application. In order to describe the best vasodilating agent for preparation of the ITA, a randomized double-blind placebo controlled clinical work was performed in a group of CABG patients. Methods: Three hundred consecutive patients submitted for elective first time coronary artery bypass grafting were randomly subdivided into five groups. The first measurement was performed shortly after the internal thoracic artery was dissected from the chest wall and the second just prior to performing distal anastomosis to the left anterior descending coronary artery. During the time interval between the two measurements topical vasodilator has been injected into the endothoracic fascia of the ITA using the following drugs: papaverine 2 mg/ml, nitrogly-cerin 1 mg/ml, nitroprusside 0.5 mg/ml, mixed solution include sodium nitroprusside (1 mg/ml) and diltiazem (0.5 mg/ml) and normal saline 0.9%. Results: No statistically significant differences were found between the groups in respect to age, body surface area, cardiopulmonary bypass time, cross clamping time, and time interval between the two flow measurements. Mean arterial pressure at the time of the first and second internal thoracic artery flow measurements did not show statistically significant differences either within or between the groups. In all five groups, the free flow of the internal thoracic artery increased significantly with time. However, no statistically significant differences were shown between the five groups with respect to second flow. Conclusions: We suggest that preparation of the ITA by topical vasodilators injection into the endothoracic fascia does not result in a significantly superior free flow than placebo.

关键词： Coronary Artery Disease Vasospasm Topical Vasodilators

Isolated tricuspid valve infective endocarditis in young drug abusers

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World Journal of Cardiovascular Diseases 2012年第3期2卷 201-203页

Isolated tricuspid valve infective endocarditis (TVIE) is a rare clinical condition. Thus, there is no common consensus for the treatment options for TVIE. Vege-tectomy and valvulectomy, valve repair, and valve replacement, which are controversial in regard to hemodynamic consequences in right-sided low-pressure system and long-term prognosis. We present 2 young intravenous drug users with TVIE and our surgical strategy.

关键词： Infective Endocarditis Tricuspid Valve Replacement Intravenous Drugs

Successful mitral valve replacement in a young pregnant patient

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World Journal of Cardiovascular Diseases 2012年第3期2卷 151-154页

作者： Omer Faruk Dogan Habib Cakir cenap Ozkara Aytul Erciyes Department of Cardiovascular Surgery Adana Numune Education and Training HospitalAdanaTurkey Department of Cardiovascular Surgery Corlu Sifa HospitalIstanbulTurkey Department of Cardiovascular Surgery Karadeniz Eregli Devlet HastanesiKaradenizTurkey

Pregnancy in women with mechanical prosthetic heart valves is associated with an increased risk of maternal and fetal complications. Managing of the anticoagulation of these patients is very important for life saving of mother and fetus. Unfortunately, throm- boembolic complications in some pregnant women with mechanical mitral valve can be seen. Herein, we present urgent mechanical mitral valve replacement in a 27 year old pregnant woman due to stuck mecha- nical valve.

关键词： Pregnancy Mitral Valve Prosthesis Thrombosis