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Extrahepatic cholestasis associated with paracoccidioidomycosis:Challenges in the differential diagnosis of biliopancreatic neoplasia

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World Journal of gastrointestinal Oncology 2024年第6期16卷 2531-2540页

作者： Jose sebastiao dos santos Vitor de Moura Arrais William Jose Rosseto Ferreira Ricardo Ribeiro Correa Filho Mariangela Ottoboni Brunaldi Rafael Kemp Ajith Kumar sankanrakutty Jorge Elias Junior Fernando Bellissimo-Rodrigues Roberto Martinez Edson Zangiacomi Martinez Jose celso Ardengh Faculdade de Medicina de Ribeirao Preto da Universidade de sao Paulo(FMRP-UsP) Departamento de Cirurgia e AnatomiaRibeirao Preto 14049-900Sao PauloBrazil Universidade de sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de PatologiaRibeirao Preto 14048900Sao PauloBrazil Universidade de sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Imagens MédicasHematologia e Oncologia ClínicaRibeirao Preto 14048900Sao PauloBrazil Universidade de sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Medicina SocialRibeirao Preto 14015-010Sao PauloBrazil Universidade de sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Clínica MédicaRibeirao Preto 14015-010Sao PauloBrazil Universidade de sao Paulo Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo(FMRP-USP)Departamento de Cirurgia e AnatomiaRibeirao Preto 14049-900Sao PauloBrazil and Hospital MoriahServico de Endoscopia DigestivaSao Paulo 04084-002Sao PauloBrazil

BACKgROUND Paracoccidioidomycosis(PCM)may involve the hepatic pedicle and peripan creatic lymph nodes,cause damage to the bile duct and manifest,exceptionally,in combination with extrahepatic cholestasis(EHC),making investigation and treatment *** To investigate the management of patients with visceral PCM admitted with *** All patients diagnosed with PCM treated in a public,tertiary teaching hospital between 1982 and 2020 were retrospectively *** also identified with EHC were allocated to two groups according to the treatment approach for the purpose of comparing clinical,laboratory,and imaging findings,resources used for etiological diagnosis,treatment results,and *** analyses were performed using the linear mixed-effects model(random and fixed effects),which was adjusted using the PROC MIXED procedure of the sAs®9.0 software,and Fisher’s exact *** Of 1645 patients diagnosed with PCM,40(2.4%)had *** these,20(50.0%)lived in the rural area and 29(72.5%)were men,with a mean age of 27.1 years(3-65 years).Jaundice as first symptom and weight loss of at least 10 kg were observed in 16 patients(40.0%),and a mass in the head of the pancreas was observed in 8(20.0%).The etiological diagnosis was made by tissue collection during surgery in 4 cases(10.0%)and by endoscopic methods in 3 cases(7.5%).Twenty-seven patients(67.5%)received drug treatment alone(group 1),whereas 13(32.5%)underwent endoscopic and/or surgical procedures in combination with drug treatment(group 2).EHC was significantly reduced in both groups(40.7% in group 1,with a mean time of 3 months;and 38.4% in group 2,with a mean time of 7.5 months),with no statistically significant difference between *** recurrence rates,associated mainly with treatment nonadherence,were similar in both groups:37% in group 1 and 15.4% in group *** mortality rate was 18.5% in group 1 and 23% in group 2,with survival estimates of 71.3% and 72.5%,respectively,with

关键词： Cholestasis Jaundice Obstructive Blastomycosis Paracoccidioides Diagnosis Treatment

Influence of variables related to soil weathering on the geomechanical performance of tropical soils

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Journal of Rock Mechanics and geotechnical Engineering 2023年第9期15卷 2423-2440页

作者： Rodrigo Cesar Pierozan gregorio Luís silva Araújo Ennio Marques Palmeira celso Romanel Department of Civil Engineering Federal Institute of EducationScienceand Technology of RondoniaPorto VelhoROBrazil Department of Civil and Environmental Engineering University of BrasiliaBrasiliaDFBrazil Department of Civil and Environmental Engineering Pontifical Catholic University of Rio de JaneiroRio de JaneiroRJBrazil

This paper presents an experimental and analytical investigation of the influence of variables related to soil weathering on the geomechanical performance of sand-silt mixtures containing lateritic soils,*** weathered tropical soils with the influence of interparticle *** sand-silt mixtures containing different relative proportions between uniform sand and lateritic soil were produced,and geomechanical soil characterization tests were *** on the results,a transition from a primarily coarse-to a fine-grained prevailing soil structure was found to cause considerable impact on the geomechanical performance of these soils,as evidenced by design variables related to soil mineralogy and size distribution ***,fines contents of both individual soil particles and soil aggregations were found to correlate with experimental results,while the relative proportion between sesquioxides(aluminum,and iron oxides),and silica,***-silica ratios(ssR^(-1)),facilitated estimates concerning changes in geomechanical ***,the application of the sandsilt mixtures containing lateritic soil on soil walls reinforced with polymeric strips was also evaluated,further emphasizing the potential advantages of adopting variables related to soil weathering on design guidelines concerning tropical soils.

关键词： sesquioxides-silica ratio Tropical soils sand-silt mixtures Lateritic soil Reinforced soil walls

Current and future perspectives on acute-on-chronic liver failure: Challenges of transplantation, machine perfusion, and beyond

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World Journal of gastroenterology 2022年第48期28卷 6922-6934页

作者： Bianca Della guardia Amanda P C s Boteon celso E L Matielo guilherme Felga Yuri L Boteon Liver Unit Hospital Israelita Albert EinsteinSão Paulo 05652-900Brazil Instituto Israelita de Ensino e Pesquisa Albert Einstein Faculdade Israelita de Ciências da Saúde Albert EinsteinSão Paulo 05652-900Brazil

Acute-on-chronic liver failure(ACLF)is a syndrome that occurs in patients with chronic liver disease and is characterized by acute decompensation,organ failure and high short-term *** due to the lack of universal diagnostic criteria,the actual ACLF prevalence remains unclear;nevertheless,it is expected to be a highly prevalent condition *** transplantation is an effective protective measure for selected ACLF *** liver transplantation,diagnosing and treating precipitant events and providing supportive treatment for organ failures are currently the cornerstone of ACLF *** new clinical specific therapies have been researched,more studies are necessary to assess safety and ***,future ACLF management strategies must consider measures to improve access to liver transplantation because the time window for this life-saving therapy is frequently ***,an urgent and global discussion about allocation and prioritization for transplantation in critically ill ACLF patients is needed because there is evidence suggesting that the current model may not portray their waitlist *** addition,while donor organ quality is meant to be a prognostic factor in the ACLF setting,recent evidence suggests that machine perfusion of the liver may be a safe tool to improve the donor organ pool and expedite liver transplantation in this scenario.

关键词： Acute-on-chronic liver failure Liver cirrhosis Liver transplantation Machine perfusion Hypothermic oxygenated machine perfusion

On the viability of wearing evaluation by Thin Layer Activation in the presence of non-occupationally exposed individuals

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Nuclear science and Techniques 2022年第3期33卷 103-112页

作者： Michel de Almeida Franca Julio Cezar suita Paulo Fernando Ferreira Frutuoso e Melo celso Marcelo Franklin Lapa graduate Program of Nuclear Engineering COPPEFederal University of Rio de JaneiroRio de JaneiroRJ 21941914Brazil Instituto de Engenharia Nuclear(IEN-CNEN) Rio de Janeiro 21941614Brazil Comissao Nacional de Energia Nuclear(sEAsE/DRs/CNEN) Rio de Janeiro 22290040Brazil

Thin Layer Activation is a nuclear technique that has key advantages over other wear measuring techniques for mechanical systems,especially for in site experiments on equipment important to safety in nuclear ***,it incurs radioactive dose and,thus,must be proved radiologically safe before use,otherwise,the utilization of this technique may be hindered *** said technique is safe previous to any operational/monetary cost is key,providing a methodology for this early assertion is the main contribution of this work—here,only non-occupationally exposed individuals are *** work offers a methodology,through a case study,to ascertain the Thin Layer Activation parameters to obtain safe levels of radioactive dose while maintaining statistically reliable *** methodology consists of using simulations,through the Monte Carlo Method,to obtain the floors and ceilings for the previously mentioned activation parameters based on operation and work conditions on site.

关键词： Thin Layer Activation safety evaluation simulation Equipment wearing

Nutritional,rheological and sensory properties of butter processed with different mixtures of cow and sheep milk cream

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Food Bioscience 2022年第2期46卷 487-497页

作者： Renata s Dias celso F.Balthazar Rodrigo N.Cavalcanti Louise A.sobral Jessica F.Rodrigues Roberto P.CNeto Maria Inˆes B.Tavares Ana Paula B.Ribeiro Renato grimaldi celso sant’Anna Erick A.Esmerino Tatiana C.Pimentel Marcia Cristina silva Adriano g.Cruz Instituto Federal de Educaç˜ao Ciˆencia e Tecnologia do Rio de Janeiro(IFRJ)Departamento de AlimentosRJBrazil Universidade Estadual de Campinas(UNICAMP) Faculdade de Engenharia de AlimentosCampinasSPBrazil Universidade Federal do Rio de Janeiro(UFRJ) Escola de QuimicaRJBrazil Instituto Federal of Minas gerais(IFMg) Departamento de Ciˆencias Agr´ariasBambuíMGBrazil Universidade Federal do Rio de Janeiro(UFRJ) Instituto de Macromol´eculas Professora Eloisa Mano(IMA)Rio de JaneiroBrazil Instituto Federal do Paran´a(IFPR) ParanavaíPRBrazil g Instituto Nacional de MetrologiaNormalizaç˜ao Qualidade Industrial(affnInmetro) Duque de Caxias25250-020Rio de JaneiroBrazil Universidade Federal Fluminense(UFF) Faculdade de Medicina VeterinariaNiter´oiRJBrazil

This study assessed the quality parameters and consumer perception and behavior of butter processed with different ratios of cow and sheep milk *** milk cream butter(CMCB)showed lower moisture content and higher fat content,smaller fat globules,and higher concentrations of long-chain saturated fatty acids and monounsaturated fatty acids,resulting in improved potential health *** addition,CMCB showed yellow color,little salt,and butter taste as the main sensory characteristics,resulting in grateful and good digestibility *** milk cream addition improved the rheological properties of the products(lower viscosity,consistency index,and rigidity(J0),and higher fluidity and viscoelastic behavior(J1)),mainly due to the increased concentrations of short-chain and medium-chain saturated fatty acids and polyunsaturated fatty ***,sheep milk cream butter(sMCB)was characterized by a greasy and striking aroma,with a lower perception of good digestibility and good appearance,and a higher bitter *** association of cow and sheep milk cream could be an exciting option to obtain products with improved fatty acid profiles,health indices,and yet maintain desired rheological and sensory *** formulation with 60%sheep milk cream and 40%cow milk cream would be the suggested combination.

关键词： sheep milk Bovine milk Quality parameters Butter

soil properties characterization for land-use planning and soil management in watersheds under family farming

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International soil and Water Conservation Research 2022年第1期10卷 119-128页

作者： Jose Miguel Reichert Paulo Ivonir gubiani Danilo Rheinheimer dos santos Dalvan Jose Reinert celso Aita sandro Jose giacomini soils Department Universidade Federal de Santa Maria(UFSM)Santa MariaRSBrazil

Environmental monitoring of small,rural watersheds was one of the components of the Natural Re-sources Management and Rural Poverty Alleviation Program(Rs-Rural)in southern *** purpose of the monitoring was to assess the impact of promoting soil conservation and environment manage-ment practices adopted by farmers and funded by the *** four small monitored watersheds,in a total of 95 plots representing distinct land use and soil management,surface soil was collected to characterize ground-zero of the Program by determining several soil physical,chemical and microbio-logical *** component analysis(PCA)shows soil physical,chemical and biological properties were decisive in defining the agricultural soils in the rural watersheds with family *** sensitivity to chemical properties provides an opportunity to improve soil quality if soil management focuses on altering those *** management practiced by tobacco farmers leads to rapid,intense degradation of some natural soil properties,especially those related to the dynamics of soil organic matter,compared with more conservationist uses(forest,regrowth,and grassland).Thus,soil management must be reoriented to avoid the progress of degradation and recover soil physical and biological *** crops and by land-abandonment to allow natural vegetation are important management strategies for the degraded soils used for tobacco production,increasing soil organic matter,nutrients and microbial activity and thus allowing further crop *** conclusion,wa-tersheds with tobacco cropping have soils with lower quality than when under no-tillage grain pro-duction,requiring changes in land use and soil management.

关键词： Natural resources management Environmental monitoring soil conservation soil quality Alleviating poverty

Formation, Propagation and Reflection of 1D Normal shocks in Riemann shock Tube

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Applied Mathematics 2022年第3期13卷 295-323页

作者： Karan s. surana Jacob K. Kendall celso H. Carranza Mechanical Engineering University of Kansas Lawrence USA

The purpose of this paper is to consider 1D Riemann shock tube to investigate the formation and propagation of compression waves leading to formation, propagation and reflection of 1D normal shocks using simplified mathematical models commonly used in the published work as well as using complete mathematical models based on Conservation and Balance Laws (CBL) of classical continuum mechanics and constitutive theories for compressible viscous medium derived using entropy inequality and representation theorem. This work is aimed at resolving compression waves, the shock structure, shock formation, propagation and reflection of fully formed shocks. Evolutions obtained from the mathematical models always satisfy differentiability requirements in space and time dictated by the highest order of the derivatives of the dependent variables in the mathematical models investigated. All solutions reported in this paper including boundary conditions and initial conditions are always analytic. solutions of the mathematical models are obtained using the space-time finite element method in which the space-time integral forms are space-time variationally consistent ensuring unconditionally stable computations during the entire evolution. solution for a space-time strip or slab is calculated and is time marched upon convergence to obtain complete evolution for the desired space-time domain, thus ensuring time accurate evolutions. The space-time local approximation over a space-time element of a space-time strip or slab is p-version hierarchical with higher-order global differentiability in space and time, i.e., we consider scalar product approximation spaces in which k = (ksub>1sub>, ksub>2sub>) are the order of the space in space and time and p = (psub>1sub>, psub>2sub>) are p-levels of the approximations in space and time. Model problem studies are presented for different mathematical models and are compared with solutions obtained from the complete mathematical model b

关键词： Compression Wave 1D Normal shock Riemann shock Tube space-Time

Level spacing statistics for two-dimensional massless Dirac billiards

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Chinese Physics B 2014年第7期23卷 41-52页

作者：黄亮徐洪亚来颖诚 celso grebogid Institute of Computational Physics and Complex systems and Key Laboratory for Magnetism and Magnetic Materials of MOE Lanzhou University school of Electrical Computerand Energy EngineeringArizona State University Department of Physics Arizona State University Institute for Complex systems and Mathematical Biology School of Natural and Computing SciencesKing's CollegeUniversity of Aberdeen

Classical-quantum correspondence has been an intriguing issue ever since quantum theory was proposed. The search- ing for signatures of classically nonintegrable dynamics in quantum systems comprises the interesting field of quantum chaos. In this short review, we shall go over recent efforts of extending the understanding of quantum chaos to relativistic cases. We shall focus on the level spacing statistics for two-dimensional massless Dirac billiards, i.e., particles confined in a closed region. We shall discuss the works for both the particle described by the massless Dirac equation （or Weyl equation） and the quasiparticle from graphene. Although the equations are the same, the boundary conditions are typically different, rendering distinct level spacing statistics.

关键词： quantum chaos level spacing statistics Dirac billiards graphene billiards

stochastic Computational Heuristic for the Fractional Biological Model Based on Leptospirosis

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Computers, Materials & Continua 2023年第2期74卷 3455-3470页

作者： Zulqurnain sabir sánchez-Chero Manuel Muhammad Asif Zahoor Raja gilder-Cieza–Altamirano María-Verónica seminario-Morales Fernández Vásquez JoséArquímedes Purihuamán Leonardo celso Nazario Thongchai Botmart Wajaree Weera Department of Mathematics and statistics Hazara UniversityMansehraPakistan Universidad Nacional de Frontera SullanaPiuraPerú Future Technology Research Center National Yunlin University of Science and Technology123 University RoadSection 3Douliou64002YunlinTaiwan Universidad Nacional Autónoma de Chota CajamarcaPerú Universidad Cesar Vallejo TrujilloLa LibertadPerú Universidad señor de sipán ChiclayoPerú Department of Mathematics Faculty of ScienceKhon Kaen UniversityKhon Kaen40002Thailand

The purpose of these investigations is to find the numerical outcomes of the fractional kind of biological system based on Leptospirosis by exploiting the strength of artificial neural networks aided by scale conjugate gradient,called *** fractional derivatives have been applied to get more reliable performances of the *** mathematical form of the biological Leptospirosis system is divided into five categories,and the numerical performances of each model class will be provided by using the *** exactness of the ANNs-sCg is performed using the comparison of the reference and obtained *** reference solutions have been obtained by using theAdams numerical *** these investigations,the data selection is performed at 82%for training,while the statics for both testing and authentication is selected as 9%.The procedures based on the recurrence,mean square error,error histograms,regression,state transitions,and correlation will be accomplished to validate the fitness,accuracy,and reliability of the ANNs-sCg scheme.

关键词： Fractional leptospirosis biological model artificial neural networks scale conjugate gradient numerical performances