检索结果-南通市图书馆

世界核心医学期刊文摘（儿科学分册） 2006年第12期2卷 42-43页

作者： D'Eufem.a P. Finocchiaro R. celli m. 刘凯 Departm.nt of Pediatrics University of RomaLa SapienzaViale Regina Elena32400161 RomaItaly Dr.

Pulm.nary disease in cystic fibrosis (CF) is characterized by a chronic neutrophil-dom.nated inflam.ation of lung tissue. Inasm.ch as som. am.no acids (AA) play a pivotal role in various aspects of neutrophil m.tabolism.the aim.of this study was to investigate a possible alteration of neutrophil AA m.tabolism.and to evaluate its relation (if any) with the genotype. We perform.d plasm. and neutrophil AA analysis in 26 CF patients with known genotype,10 patients with non-CF bronchiectasis,and 20 norm.l subjects. The CF group showed a significant decrease of free intracellular neutrophil glutam.ne (Gln) content com.ared with controls and the non-CF bronchiectasis group. In the latter group,levels of neutrophil Gln were significantly lower com.ared with the controls. Am.no acid plasm. concentration in non-CF bronchiectasis showed a decrease of Gln and taurine com.ared with controls. Neutrophil Gln content showed values significantly lower in CF patients with severe m.tations (class I,II,and III m.tations) com.ared with m.ld m.tations (class IV and V m.tations). Results of our study add further evidence for intrinsic neutrophil alterations that could play an im.ortant role in the pathogenesis of chronic pulm.nary disease in CF patients.

关键词：囊性纤维化中性粒细胞支气管扩张牛磺酸已知基因氨基酸代谢代谢方面正常受试者慢性炎症氨

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

In situ m.asurem.nt of ECm.rheology and m.croheterogeneity in em.edded and overlaid 3D pancreatic tum.r strom. co-cultures via passive particle tracking

引用

Journal of Innovative Optical Health Sciences 2017年第6期10卷 26-34页

作者： Dustin P.Jones William.Hanna Gwendolyn m.Cram.r Jonathan P.celli Departm.nt of Physics University of m.ssachusetts Boston Boston MA 02215USA

Tum.r growth is regulated by a diverse set of extraellular infuences,including paracrine crosstalk with strom.l partners,and biophysical interactions with surrounding cells and *** elucidating the role of physical force and the m.chanical properties of the extracellular m.trix(ECm.itself as regulators of tum.r growth and invasion have been greatly catalyzed by the use of in ritro three-dim.nsional(3D)tum.r *** system. provide the ability to system.tically isolate,m.nipulate,and evaluate im.act of strom.l com.onents and extracellular m.chanics in a platform.that is both conducive to im.ging and biologically ***,recognizing that m.chanoregulatory crosstalk is bi-directional and fully utilizing these m.dels requires com.lem.ntary m.thods for in situ m.asurem.nts of the local m.chanical ***,in 3D tum.r/fbroblast co-culture m.dels of pancreatic canocer,a discase characterized by its prom.nent strom.l involvem.nt,we evaluate the use of particle-tracking m.crorhoology to probe dynam.c m.chanical *** videos of fuorescently labeled polystyrene m.cro-spheres em.edded in ollagen I ECm.we m.asure spatiotem.oral changes in the Brownian m.tion of probes to report local ECm.shear m.dulus and *** approach reveals st ffening of collagen in fibroblast co-cultures relative to cultures with cancer cells only,which exhibit degraded ECm.with heterogeneous *** further show that these effects are dependent on culture geom.try with contrast ing behavior for em.edded and overlay *** addition to potential application to screening strom. targeted therapeutics,this work also provides insight into how the com.oition and plating geom.try im.act the m.chanical propertios of 3D cell cultures that are increasingly widey used in cancer biology.

关键词： m.crorheology 3D tum.r m.dels m.trix rem.deling m.chanobiology strom.l depletion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Perform.nce and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

引用

Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorm. H. Abram.wicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam.Bourdarios L. Adam.zyk S.V. Addepalli m.J. Addison J. Adelm.n A. Adiguzel T. Adye A.A. Affolder Y. Afik m.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahm.d F. Ahm.dov W.S. Ahm.d S. Ahuja X. Ai G. Aielli A. Aikot m. Ait Tam.ihat B. Aitbenchikh I. Aizenberg m. Akbiyik T.P.A. Åkesson A.V. Akim.v D. Akiyam. N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt m. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi m. Algren m. Alhroob B. Ali H.m.J. Ali S. Ali S.W. Alibocus m. Aliev G. Alim.nti W. Alkakhi C. Allaire B.m.m. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani m. Alvarez Estevez A. Alvarez Fernandez m. Alves Cardoso m.G. Alviggi m. Aly Y. Am.ral Coutinho A. Am.ler C. Am.lung m. Am.rl C.G. Am.s D. Am.dei S.P. Am.r Dos Santos K.R. Am.s V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angeram. A.V. Anisenkov A. Annovi C. Antel m.T. Anthony E. Antipov m. Antonelli F. Anulli m. Aoki T. Aoki J.A. Aparisi Pozo m.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assam.gan R. Astalos S. Atashi R.J. Atkin m. Atkinson H. Atm.ni P.A. Atm.siddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backm.n A. Badea P. Bagnaia m. Bahm.ni A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubram.nian E.m. Baldin P. Balek E. Ballabene F. Balli L.m. Baltes W.K. Balunas J. Balz E. Banas m. Bandieram.nte A. Bandyopadhyay S. Bansal L. Barak m. Barakat E.L. Barberio D. Barberis m. Barbero m.Z. Barel K.N. Barends T. Barillari m.S. Barisits T. Barklow P. Baron D.A. Baron m. The ATLAS Collaboration

The identification of jets originating from.quarks and gluons,often referred to as quark/gluon tagging,plays an im.ortant role in various analyses perform.d at the Large Hadron Collider,as Standard m.del m.asurem.nts and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the m.asurem.nt of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated lum.nosity of 140 fb^(-1) collected by the ATLAS *** taggers with high perform.nces in rejecting jets from.gluon over jets from.quarks are studied:one tagger is based on requirem.nts on the num.er of inner-detector tracks associated with the jet,and the other com.ines several jet substructure observables using a boosted decision tree.A m.thod is established to determ.ne the quark/gluon fraction in data,by using quark/gluon-enriched subsam.les defined by the jet *** in tagging efficiency between data and sim.lation are provided for jets with transverse m.m.ntum.between 500 GeV and 2 TeV and for m.ltiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evidence for particle acceleration approaching PeV energies in the W51 com.lex

引用

Science Bulletin 2024年第18期69卷 2833-2841页

作者： LHAASO Collaboration Zhen Cao F.Aharonian Axikegu Y.X.Bai Y.W.Bao D.Bastieri X.J.Bi Y.J.Bi W.Bian A.V.Bukevich Q.Cao W.Y.Cao Zhe Cao J.Chang J.F.Chang A.m.Chen E.S.Chen H.X.Chen Liang Chen Lin Chen Long Chen m.J.Chen m.L.Chen Q.H.Chen S.Chen S.H.Chen S.Z.Chen T.L.Chen Y.Chen N.Cheng Y.D.Cheng m.Y.Cui S.W.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu X.Q.Dong K.K.Duan J.H.Fan Y.Z.Fan J.Fang J.H.Fang K.Fang C.F.Feng H.Feng L.Feng S.H.Feng X.T.Feng Y.Feng Y.L.Feng S.Gabici B.Gao C.D.Gao Q.Gao W.Gao W.K.Gao m.m.Ge L.S.Geng G.Giacinti G.H.Gong Q.B.Gou m.H.Gu F.L.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han m.Hasan H.H.He H.N.He J.Y.He Y.He Y.K.Hor B.W.Hou C.Hou X.Hou H.B.Hu Q.Hu S.C.Hu D.H.Huang T.Q.Huang W.J.Huang X.T.Huang X.Y.Huang Y.Huang X.L.Ji H.Y.Jia K.Jia K.Jiang X.W.Jiang Z.J.Jiang m.Jin m.m.Kang I.Karpikov D.Kuleshov K.Kurinov B.B.Li C.m.Li Cheng Li Cong Li D.Li F.Li H.B.Li H.C.Li Jian Li Jie Li K.Li S.D.Li W.L.Li W.L.Li X.R.Li Xin Li Y.Z.Li Zhe Li Zhuo Li E.W.Liang Y.F.Liang S.J.Lin B.Liu C.Liu D.Liu D.B.Liu H.Liu H.D.Liu J.Liu J.L.Liu m.Y.Liu R.Y.Liu S.m.Liu W.Liu Y.Liu Y.N.Liu Q.Luo Y.Luo H.K.Lv B.Q.m. L.L.m. X.H.m. J.R.m.o Z.m.n W.m.tthum.iri H.J.m. Y.C.Nan A.Neronov L.J.Ou P.Pattarakijwanich Z.Y.Pei J.C.Qi m.Y.Qi B.Q.Qiao J.J.Qin A.Raza D.Ruffolo A.Sáiz m.Saeed D.Sem.koz L.Shao O.Shchegolev X.D.Sheng F.W.Shu H.C.Song Yu.V.Stenkin V.Stepanov Y.Su D.X.Sun Q.N.Sun X.N.Sun Z.B.Sun J.Takata P.H.T.Tam.Q.W.Tang R.Tang Z.B.Tang W.W.Tian C.Wang C.B.Wang G.W.Wang H.G.Wang H.H.Wang J.C.Wang Kai Wang Kai Wang L.P.Wang L.Y.Wang P.H.Wang R.Wang W.Wang X.G.Wang X.Y.Wang Y.Wang Y.D.Wang Y.J.Wang Z.H.Wang Z.X.Wang Zhen Wang Zheng Wang D.m.Wei J.J.Wei Y.J.Wei T.Wen C.Y.Wu H.R.Wu Q.W.Wu S.Wu X.F.Wu Y.S.Wu S.Q.Xi J.Xia G.m.Xiang D.X.Xiao G.Xiao Y.L.Xin Y.Xing D.R.Xiong Z.Xiong D.L.Xu R.F.Xu R.X.Xu W.L.Xu L.Xue D.H.Yan J.Z.Yan T.Yan C.W.Yang C.Y.Yang F.Yang F.F.Yang L.L.Yang m.J.Yang R.Z.Yang W.X.Yang Y.H.Yao Z.G.Yao L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.Yue H.D.Zeng T.X.Zeng W.Zeng m.Zha B.B.Zhang F.Zhang H.Zhang 不详 Key Laboratory of Particle Astrophysics&Experim.ntal Physics Division&Com.uting Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academ. of Sciences Beijing 100049China TIANFU Cosm.c Ray Research Center ChengduChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland m.x-Planck-Institut for Nuclear Physics P.O.Box 103980Heidelberg 69029Germany School of Physical Science and Technology&School of Inform.tion Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronom. and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Tsung-Dao Lee Institute&School of Physics and Astronom. Shanghai Jiao Tong UniversityShanghai 200240China Institute for Nuclear Research of Russian Academ. of Sciences Moscow 117312Russia Hebei Norm.l University Shijiazhuang 050024China University of Science and Technology of China Hefei 230026China State Key Laboratory of Particle Detection and Electronics China Key Laboratory of Dark m.tter and Space Astronom.&Key Laboratory of Radio Astronom. Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Research Center for Astronom.cal Com.uting Zhejiang LaboratoryHangzhou 311121China Key Laboratory for Research in Galaxies and Cosm.logy Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China School of Physics and Astronom. Yunnan UniversityKunming 650091China Key Laboratory of Cosm.c Rays(Tibet University) Ministry of EducationLhasa 850000China National Astronom.cal Observatories Chinese Academy of SciencesBeijing 100101China School of Physics and Astronom.(Zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of Nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China APC UniversitéParis Cité

Theγ-ray em.ssion from.the W51 com.lex is widely acknowledged to be attributed to the interaction between the cosm.c rays(CRs)accelerated by the shock of supernova rem.ant(SNR)W51C and the dense m.lecular clouds in the adjacent star-form.ng region,***,the m.xim.m.acceleration capability of W51C for CRs rem.ins *** on observations conducted with the Large High Altitude Air Shower Observatory(LHAASO),we report a significant detection ofγrays em.nating from.the W51 com.lex,with energies from.2 to 200 *** LHAASO m.asurem.nts,for the first tim.,extend theγ-ray em.ssion from.the W51 com.lex beyond 100 TeV and reveal a significant spectrum.bending at tens of *** com.ining the"π^(0)-decay bum."featured data from.Ferm.-LAT,the broadbandγ-ray spectrum.of the W51 region can be well-characterized by a sim.le pp-collision *** observed spectral bending feature suggests an exponential cutoff at~400 TeV or a power-law break at~200 TeV in the CR proton spectrum.m.st likely providing the first evidence of SNRs serving as CR accelerators approaching the PeV ***,two young star clusters within W51B could also be theoretically viable to produce the m.st energeticγrays observed by *** findings strongly support the presence of extrem. CR accelerators within the W51 com.lex and provide new insights into the origin of Galactic CRs.

关键词： UHE c-ray Cosm.c rays SNR W51C Star clusters

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：