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Pete's Dragon

小学生时代（大嘴英语） 2024年第2期 32-37页

作者： celine 不详

老木匠米查姆先生(MrMeacham)总爱和镇上的孩子们讲一个故事:在茂密的森林里,有一只全身覆盖着绿毛、红眼晴、会喷火的巨龙·他绘声绘色地形容着龙的样貌,讲述自己见到龙的经历,但没人相信这个听起来有些荒诞的故事。米查姆的女儿格蕾丝... 详细信息

老木匠米查姆先生(MrMeacham)总爱和镇上的孩子们讲一个故事:在茂密的森林里,有一只全身覆盖着绿毛、红眼晴、会喷火的巨龙·他绘声绘色地形容着龙的样貌,讲述自己见到龙的经历,但没人相信这个听起来有些荒诞的故事。米查姆的女儿格蕾丝(Grace)对父亲所说的也有些不屑一顾,表示自己作为护林员,每天和那片森林打交道,但从没见过父亲所说的“龙”。

关键词：护林员格蕾丝绘声绘色荒诞故事森林

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2024年马来西亚国际家具展共创商机

家具与室内装饰 2024年第4期31卷 70-73页

作者： celine Yuen 不详

创展30周年的马来西亚国际家具展(MIFF)圆满落幕,参展商和买家对为期四天的展会赞誉有加,再次证明了MIFF是为全球家具业者提供展示最新产品和开拓新业务的绝佳平台。该展会于3月1日至4日举行,为包括马来西亚在内的15个国家和地区的715... 详细信息

创展30周年的马来西亚国际家具展(MIFF)圆满落幕,参展商和买家对为期四天的展会赞誉有加,再次证明了MIFF是为全球家具业者提供展示最新产品和开拓新业务的绝佳平台。该展会于3月1日至4日举行,为包括马来西亚在内的15个国家和地区的715家参展商提供商机,让参展商与来自全球各地正在寻求诚信可靠供应商及高品质民用和商用家具的买家洽商交流。

关键词：参展商供应商马来西亚买家商机展会诚信家具

2024马来西亚国际家具展引入全新展会体验

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家具与室内装饰 2024年第2期31卷 94-95页

作者： celine 不详

随着国际需求的激增,马来西亚国际家具展(MIFF)的展会规模再次扩大,使这个东南亚非常大的家具盛会在其30周年之际比以往任何时候都更为壮观。这届具有里程碑意义的展会将于3月1日至4日,在两个展览场地,即马来西亚国际贸易展览中心(MITEC... 详细信息

随着国际需求的激增,马来西亚国际家具展(MIFF)的展会规模再次扩大,使这个东南亚非常大的家具盛会在其30周年之际比以往任何时候都更为壮观。这届具有里程碑意义的展会将于3月1日至4日,在两个展览场地,即马来西亚国际贸易展览中心(MITEC)和吉隆坡世界贸易中心(WTCKL)举行。目前,两大展馆均已达到参展商满员的状态。据主办机构InformaMarkets Malaysia指出,MIFF将迎来一个更繁忙的家具采购季,展会所积累的国际影响力将吸引越来越多来自全球各地的高素质国际买家到访。

关键词：贸易展览展览场地世界贸易中心马来西亚国际参展商国际买家展会规模家具采购

马来西亚国际家具贸易展欢庆30周年,展望未来

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家具与室内装饰 2024年第1期31卷 62-63页

作者： celine 不详

东南亚规模极大、具有全球影响力的家具商贸展,即马来西亚国际家具贸易展(MIFF)在2023年12月8日举办了“MIFF30周年庆晚宴”,与马来西亚家具从业者共庆了2024年展会即将迎来的三十周年里程碑。此次晚宴齐聚了500位嘉宾、参展商和商业合... 详细信息

东南亚规模极大、具有全球影响力的家具商贸展,即马来西亚国际家具贸易展(MIFF)在2023年12月8日举办了“MIFF30周年庆晚宴”,与马来西亚家具从业者共庆了2024年展会即将迎来的三十周年里程碑。此次晚宴齐聚了500位嘉宾、参展商和商业合作伙伴,一起回顾展会三十年以来的荣耀历程。这高光时刻不仅仅给予展会,更是为马来西亚家具业的企业家精神及不凡成就致敬。

关键词：商业合作伙伴企业家精神展望未来家具业参展商全球影响力马来西亚晚宴

Beta-HCG Levels and Ovarian Ultrasonography Results among Non-Pregnant Women of Reproductive Age in Port Harcourt, Nigeria: A Cross-Sectional Study

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Journal of Biosciences and Medicines 2024年第5期12卷 233-241页

作者： celine C. Agonsi Francis Anacletus Joel Aluko Chinemerem Eleke Joy C. Samuel African Centre of Public Health and Toxicological Research (ACE-PUTOR) University of Port Harcourt Choba Nigeria Department of Nursing Science University of Port Harcourt Choba Nigeria

Background: Certain ovarian cancers that were previously common in postmenopausal women are now increasingly observed in women of reproductive age. The research on using β-HCG as a diagnostic biomarker for ovarian cancer in women of reproductive age is ongoing. Aim: This study assessed the level of serum β-HCG in non-pregnant women of reproductive age and determined its potential association with suspicious ovarian ultrasonography results. Methods: The study was conducted in Port Harcourt, Nigeria. This study adopted a cross-sectional design on a quota sample of 224 case notes of women aged 18 - 40 years obtained from eight diagnostic centres. A data extraction form was used for data collection. Data analysis employed descriptive statistics, Chi-square, Fisher’s exact test, and Odds Ratio at 95% confidence and 5% significance levels. Results: About 5.8% of the participants exhibited detectable levels of serum β-HCG above 5 IU/L (World Health Organization reference) at a mean concentration of 5.87 (±1.75) IU/L. About 4.0% of the participants had suspicious ovarian lesions identified through ultrasonography. Participants with elevated serum β-HCG levels above the WHO reference were 59 times more likely to have suspicious ovarian lesions (Odds ratio: 59.4, 95%CI: 12.3 - 287.8, p β-HCG level and age (p = 0.041) as well as parity (p Conclusion: Serum β-HCG levels above the WHO reference in non-pregnant women were associated with suspicious ovarian lesions. More rigorous primary research, systematic reviews, and meta-analyses are needed to confirm the findings of this study.

关键词： Biomarkers Ovarian Cancer Pregnancy Ultrasonography

Effects of SARS-CoV-2 infection on incidence and treatment strategies of hepatocellular carcinoma in people with chronic liver disease

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World Journal of Hepatology 2024年第2期16卷 211-228页

作者： Lung-Yi Mak Matthew Shing Hin Chung Xue Li Francisco Tsz Tsun Lai Eric Yuk Fai Wan celine Sze Ling Chui Franco Wing Tak Cheng Esther Wai Yin Chan Ching Lung Cheung Ivan Chi Ho Au Xi Xiong Wai-Kay Seto Man-Fung Yuen Carlos King Ho Wong Ian Chi Kei Wong Department of Medicine The University of Hong KongHong KongChina State Key Laboratory of Liver Research The University of Hong KongHong KongChina Department of Pharmacology and Pharmacy The University of Hong KongHong KongChina Laboratory of Data Discovery for Health(D24H) Hong Kong Science and Technology ParkHong KongChina Department of Family Medicine and Primary Care The University of Hong KongHong KongChina School of Nursing The University of Hong KongHong KongChina School of Public Health The University of Hong KongHong KongChina Research Department of Practice and Policy University College LondonLondon WC1E 6BTUnited Kingdom Aston School of Pharmacy Aston UniversityBirmingham B47ETUnited Kingdom

BACKGROUND Chronic liver disease(CLD)was associated with adverse clinical outcomes among people with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.AIM To determine the effects of SARS-CoV-2 infection on the incidence and treatment strategy of hepatocellular carcinoma(HCC)among patients with CLD.METHODS A retrospective,territory-wide cohort of CLD patients was identified from an electronic health database in Hong Kong.Patients with confirmed SARS-CoV-2 infection[coronavirus disease 2019(COVID-19)+CLD]between January 1,2020 and October 25,2022 were identified and matched 1:1 by propensity-score with those without(COVID-19-CLD).Each patient was followed up until death,outcome event,or November 15,2022.Primary outcome was incidence of HCC.Secondary outcomes included all-cause mortality,adverse hepatic outcomes,and different treatment strategies to HCC(curative,non-curative treatment,and palliative care).Analyses were further stratified by acute(within 20 d)and post-acute(21 d or beyond)phases of SARS-CoV-2 infection.Incidence rate ratios(IRRs)were estimated by Poisson regression models.RESULTS Of 193589 CLD patients(>95%non-cirrhotic)in the cohort,55163 patients with COVID-19+CLD and 55163 patients with COVID-19-CLD were included after 1:1 propensity-score matching.Upon 249-d median follow-up,COVID-19+CLD was not associated with increased risk of incident HCC(IRR:1.19,95%CI:0.99-1.42,P=0.06),but higher risks of receiving palliative care for HCC(IRR:1.60,95%CI:1.46-1.75,P<0.001),compared to COVID-19-CLD.In both acute and post-acute phases of infection,COVID-19+CLD were associated with increased risks of allcause mortality(acute:IRR:7.06,95%CI:5.78-8.63,P<0.001;post-acute:IRR:1.24,95%CI:1.14-1.36,P<0.001)and adverse hepatic outcomes(acute:IRR:1.98,95%CI:1.79-2.18,P<0.001;post-acute:IRR:1.24,95%CI:1.13-1.35,P<0.001),compared to COVID-19-CLD.CONCLUSION Although CLD patients with SARS-CoV-2 infection were not associated with increased risk of HCC,they were more likely to receive palliative treatment

关键词： SARS-CoV-2 infection Chronic liver disease Long COVID Post-COVID-19 syndrome Cirrhosis Hepatocellular carcinoma

Prenatal multiple micronutrient-fortified balanced energy-protein supplementation and newborn telomere length and mitochondrial DNA content: a randomized controlled efficacy trial in rural Burkina Faso

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Food Science and Human Wellness 2024年

作者： Giles T.Hanley-Cook Yuri Bastos-Moreira Dries S.Martens Trenton Dailey-Chwalibóg Laeticia celine Toe Brenda de Kok Lionel Ouédraogo Alemayehu Argaw Kokeb Tesfamariam Patrick Kolsteren Lieven Huybregts Tim S.Nawrot Sarah De Saeger Marthe De Boevre Carl Lachat Department of Food Technology Safety and Health Faculty of Bioscience Engineering Ghent University Center of Excellence in Mycotoxicology and Public Health MYTOXSOUTH~(?) Coordination Unit Faculty of Pharmaceutical Sciences Ghent University Centre for Environmental Sciences Hasselt University Unité Nutrition et Maladies Métaboliques Institut de Recherche en Sciences de la Santé (IRSS) Centre Muraz Center of Excellence in Mycotoxicology and Public Health MYTOXSOUTH? Coordination Unit Faculty of Pharmaceutical Sciences Ghent University Nutrition Diets and Health Unit Department of Food and Nutrition Policy International Food Policy Research Institute (IFPRI) Department of Public Health & Primary Care University of Leuven Department of Biotechnology and Food Technology Faculty of Science University of Johannesburg Doornfontein Campus

Background: Evidence regarding the effectiveness of prenatal nutritional supplements has mainly considered anthropometric pregnancy outcomes. The effect on markers of health and disease， such as offspring telomere length (TL) and mitochondrial DNA content (mtDNAc) is unknown. Objectives: We assessed the efficacy of maternal multiple micronutrient (MMN)-fortified balanced-energy protein (BEP) and iron-folic acid (IFA) supplementation on newborn TL as a secondary outcome and mtDNAc as a non-declared outcome. Design: We conducted a randomized controlled trial in rural Burkina Faso， among pregnant females (15-40 years old) enrolled at 0.05) by adjusting the regression models for potential prognostic factors of study outcomes at enrollment. Exploratory analyses indicated higher， but non-significantly different mtDNAc among children born either small-for-gestational age， low birthweight， or preterm. Conclusions: Newborns from mothers who received daily nutritional supplements across gestation did not have different relative TL or mtDNAc.

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Deep Root Memory Optimized Indexing Methodology for Image Search Engines

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Computer Systems Science & Engineering 2022年第2期40卷 661-672页

作者： R.Karthikeyan A.celine Kavida P.Suresh Department CSE Vel Tech HighTech Dr.Rangarajan Dr.Sakunthala Engineering CollegeChennai600062TamilnaduIndia Department of Physics Vel Tech Multitech Dr.Rangarajan Dr.Sakunthala Engineering CollegeChennai600062Tamil NaduIndia Department of ECE Veltech Rangarajan Dr Sagunthala R&D Institute of Science and TechnologyChennaiTamilnadu600062India

Digitization has created an abundance of new information sources by altering how pictures are captured.Accessing large image databases from a web portal requires an opted indexing structure instead of reducing the contents of different kinds of databases for quick processing.This approach paves a path toward the increase of efficient image retrieval techniques and numerous research in image indexing involving large image datasets.Image retrieval usually encounters difficulties like a)merging the diverse representations of images and their Indexing,b)the low-level visual characters and semantic characters associated with an image are indirectly proportional,and c)noisy and less accurate extraction of image information(semantic and predicted attributes).This work clearly focuses and takes the base of reverse engineering and de-normalizing concept by evaluating how data can be stored effectively.Thus,retrieval becomes straightforward and rapid.This research also deals with deep root indexing with a multidimensional approach about how images can be indexed and provides improved results in terms of good performance in query processing and the reduction of maintenance and storage cost.We focus on the schema design on a non-clustered index solution,especially cover queries.This schema provides a filter predication to make an index with a particular content of rows and an index table called filtered indexing.Finally,we include non-key columns in addition to the key columns.Experiments on two image data sets‘with and without’filtered indexing show low query cost.We compare efficiency as regards accuracy in mean average precision to measure the accuracy of retrieval with the developed coherent semantic indexing.The results show that retrieval by using deep root indexing is simple and fast.

关键词： Multi-dimensional indexing deep root hashing image retrieval filtered indexing

Antigen unmasking does not improve the visualization of phospholipase C zeta in human spermatozoa

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Asian Journal of Andrology 2022年第4期24卷 345-352页

作者： Xin Meng celine Jones Pedro Melo Caroline Ross Ginny Mounce Tim Child Kevin Coward Nuffield Department of Women's and Reproductive Health University of OxfordOxford OX39DUUK The Women's Centre Oxford University Hospitals NHS Foundation TrustOxford OX39DUUK xford Fertility Oxford Business Park NorthOxford OX42HWUK.

Phospholipase C zeta(PLCζ)is a sperm-specific protein that triggers oocyte activation.The analysis of PLCζexpression in human spermatozoa can be used as a diagnostic marker for oocyte activation deficiency.Our laboratory has previously optimized a standard"in-house"assay to determine PLCζexpression in human spermatozoa.However,one study has suggested that an antigen unmasking method(AUM)would be more efficient in visualizing PLCζin human sperm.This study aimed to compare our established assay and AUM(involving HCl,acidic Tyrode's solution[AT],and heat).The mean relative fluorescence(RF)intensity of PLCζin frozen-thawed spermatozoa from fourteen fertile donors stained with the in-house method was significantly higher than three other AUM groups(in-house[mean±standard error of mean]:18.87±2.39 arbitrary units[a.u.]vs non-AUM:11.44±1.61 a.u.,AT-AUM:12.38±1.89 a.u.,and HCl-AUM:12.51±2.16 a.u.,P<0.05,one-way analysis of variance).The mean RF intensity of PLCζin AT-and HCl-treated spermatozoa from 12 infertile males was not significantly different from that of the non-AUM group.However,the in-house method resulted in the highest RF intensity(12.11±1.36 a.u.,P<0.01).Furthermore,specificity testing of antibody-antigen binding indicated that the in-house method showed more specific binding than spermatozoa treated by the AUM.In conclusion,our in-house method showed superior visualization and reliability than the AUM,thus supporting the continued use of our in-house assay for clinical research screening.

关键词： antigen unmasking immunofluorescence staining male infertility phospholipase C zeta