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叙述空间故事转换的现代男士寓所——A Modern Mancave

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中国建筑装饰装修 2023年第15期 42-47页

作者： celia Chu celia Chu Design&Associates(CCDA)

CCDA为年轻男性户主打造的豪宅项目,展示了其在奢华舒适空间上的专业度。CCDA的设计理念超越了可视空间,延伸至每一个隐藏细节,以此彰显户主的兴趣习惯和艺术收藏品味。公寓的定制餐吧设计为餐桌、酒吧两用,呈现多样休闲用餐体验,而带... 详细信息

CCDA为年轻男性户主打造的豪宅项目,展示了其在奢华舒适空间上的专业度。CCDA的设计理念超越了可视空间,延伸至每一个隐藏细节,以此彰显户主的兴趣习惯和艺术收藏品味。公寓的定制餐吧设计为餐桌、酒吧两用,呈现多样休闲用餐体验,而带有黑色金属饰面的定制酒柜则展示了业主对品酒的兴趣。隐藏在精致皮革面板后面的威士忌吧台打开后,形成一个带有低照明环境的豪华家庭酒吧,营造放松舒适的夜间氛围。

关键词：兴趣习惯照明环境年轻男性黑色金属威士忌

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Juvenile Delinquency and Psychopathic Behavior: About a case in Abidjan

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Open Journal of Psychiatry 2022年第4期12卷 285-295页

作者： Koffi Paulin Konan Kouadio Raymond N’Guessan bla.Désirée Sandrine Ziketo Brahima Samuel Traoré Yessonguilana Jean-Marie Yeo-Tenena Department of Addictology and Mental Hygiene National Institute of Public Health Abidjan Ivory Coast UFR of Social and Human Sciences Jean Lorougnon Guédé University Daloa Ivory Coast UFR of Medical Sciences Félix Houphou&#235t-Boigny University Abidjan Ivory Coast

Violent and murderous juvenile delinquency born of the phenomenon of young people organized in gangs commonly called “microbes”, has become a real security problem for Ivorian society. It is in this context that this study has set itself the main objective of depicting the psychopathic behavior of a young “microbe” delinquent who has committed several violent crimes. It was a monographic study of the correlational-explanatory type that mobilized observation and semi-directive interviews for the production of data. The method of phenomenological analysis permits to detect traits of psychopathy in a 21-year-old youth through family history and accounts of criminal acts committed. The results of the study showed, on the one hand, a family dysfunction that gave the bed of behaviors such as the lack of empathy, the absence of remorse and the superficiality of the affects, thus translating a deficit on the level of the affective dimension. We also noted the presence of antisocial behavior such as living on the streets or in smoking rooms consuming and selling drugs. There were further implications such as theft, physical aggression and intentional homicide. According to the psychopathy literature, emotional insensitivity juxtaposed with behavior disorder was a primary combination of characteristics that help identify adolescents who exhibit psychopathic traits. Faced with this reality, this study pleads for the establishment of a special aid program to better control the deadly violence of these people.

关键词： Youth Delinquency Psychopathic Behavior Violence Abidjan

Effect of Genome-Wide Genotyping and Reference Panels on Rare Variants Imputation

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Journal of Genetics and Genomics 2012年第10期39卷 545-550页

作者： Hou-Feng Zheng Martin Ladouceur celia M.T. Greenwood J. Brent Richards Department of Medicine Human Genetics McGill University Montreal Quebec H3T 1E2 Canada Department of Epidemiology and Biostatistics Lady Davis Institute for Medical Research Jewish General Hospital Montreal Quebec H3T 1E2 Canada Research Center of Montreal Heart Institute Montreal Quebec HIT 1C8 Canada Department of Oncology McGill University Montreal Quebec H3T IE2 Canada Twin Research and Genetic Epidemiology King's College London London SE1 7EH United Kingdom

Common variants explain little of the variance of most common disease, prompting large-scale sequencing studies to understand the contribution of rare variants to these diseases. Imputation of rare variants from genome-wide genotypic arrays offers a cost-efficient strategy to achieve necessary sample sizes required for adequate statistical power. To estimate the performance of imputation of rare variants, we imputed 153 individuals, each of whom was genotyped on 3 different genotype arrays including 317k, 610k and 1 million single nucleotide polymorphisms （SNPs）, to two different reference panels： HapMap2 and 1000 Genomes pilot March 2010 release （1KGpilot） by using IMPUTE version 2. We found that more than 94% and 84% of all SNPs yield acceptable accuracy （info 〉 0.4） in HapMap2 and 1KGpilot-based imputation, respectively. For rare variants （minor allele frequency （MAF）〈5%）, the proportion of well- imputed SNPs increased as the MAF increased from 0.3% to 5% across all 3 genome-wide association study （GWAS） datasets. The proportion of well-imputed SNPs was 69%, 60% and 49% for SNPs with a MAF from 0.3% to 5% for 1M, 610k and 317k, respectively. None of the very rare variants （MAF 〈 0.3%） were well imputed. We conclude that the imputation accuracy of rare variants increases with higher density of genome-wide genotyping arrays when the size of the reference panel is small. Variants with lower MAF are more difficult to impute. These findings have important implications in the design and replication of large-scale sequencing studies.

关键词： Genotype imputation Genome-wide association study 1000 Genome Project HapMap Rare variant Common disease

Comparative performance analysis of stroke correspondence search methods for stroke-order free online multi-stroke character recognition

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Frontiers of Computer Science 2014年第5期8卷 773-784页

作者： Wenjie ca1 Seiichi UCHIDA Hiroaki SAKOE Department of Advanced Information Technology Kyushu University Fukuoka-shi 819-0395 Japan

For stroke-order free online multi-stroke charac- ter recognition, stroke-to-stroke correspondence search be- tween an input pattern and a reference pattern plays an im- portant role to deal with the stroke-order variation. Although various methods of stroke correspondence have been pro- posed, no comparative study for clarifying the relative su- periority of those methods has been done before. In this pa- per, we firstly review the approaches for solving the stroke- order variation problem. Then, five representative methods of stroke correspondence proposed by different groups, includ- ing cube search （CS）, bipartite weighted matching （BWM）, individual correspondence decision （ICD）, stable marriage （SM）, and deviation-expansion model （DE）, are experimen- tally compared, mainly in regard of recognition accuracy and efficiency. The experimental results on an online Kanji char- acter dataset, showed that 99.17%, 99.17%, 96.37%, 98.54%, and 96.59% were attained by CS, BWM, ICD, SM, and DE, respectively as their recognition rates. Extensive discussions are made on their relative superiorities and practicalities.

关键词： cube search bipartite weighted matching indi-vidual correspondence decision stable marriage deviation-expansion model

Fe掺杂ZrO_2催化剂上苯酚气相甲基化（英文）

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Chinese Journal of catalysis 2016年第11期37卷 1991-1996页

作者： celia F.Braganza A.V.Salker 果阿大学化学系

采用共沉淀法制备了Fe掺杂的ZrO_2样品,并采用X射线衍射、N_2吸附-脱附、紫外漫反射光谱、扫描电镜-电子能谱、氨程序升温脱附、X射线光电子能谱和原位红外光谱进行了表征.结果表明,Fe进入ZrO_2晶格中有效稳定了其晶相结构为单一的四方... 详细信息

采用共沉淀法制备了Fe掺杂的ZrO_2样品,并采用X射线衍射、N_2吸附-脱附、紫外漫反射光谱、扫描电镜-电子能谱、氨程序升温脱附、X射线光电子能谱和原位红外光谱进行了表征.结果表明,Fe进入ZrO_2晶格中有效稳定了其晶相结构为单一的四方相.这些样品可很好地催化苯酚气相甲基化反应,其催化活性取决于Fe含量,并与样品中L酸有关.

关键词：氧化锆铁掺杂甲基化苯酚二甲苯酚

Low-cost disordered carbons for Li/S batteries： A high- performance carbon with dual porosity derived from cherry pits

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Nano Research 2018年第1期11卷 89-100页

作者： celia Hernandez-Rentero Rafael Cordoba Noelia Moreno Alvaro caballero Julian Morales Mara Olivares-Marin Vicente Gomez-Serrano Dpto. Ouimica Inorgdnica e Ingenierfa Quimica Instituto de Quimica Fina y Nanoqufmica Universidad de C6rdoba 14071 C6rdoba Spain Dpto. Quimica Inorg6nica Facultad de Ciencias Universidad de Extremadura 06006 Badajoz Spain

A micro- and mesoporous carbon obtained from cherry pit waste and activated with HBPO4 acid has been studied as the sulfur host for Li/S batteries. The carbon has a high specific surface area of 1,662 m2·g-1 （SBET） and micropore and mesopore volumes of 0.57 and 0.40 cm3·g-1, respectively. The S/C composite, with a sulfur content of 57% deposited by the disproportionate reaction of a SaO2- solution in an acid medium without an additional heating step above the S melting point, delivers an initial specific capacity of 1,148 mah·g-1 at a current of C/16. It also has a high capacity retention of 915 mAh·g-1 after 100 cycles and a Coulombic efficiency close to 100%. The good performance of the composite was also observed under higher current rates and long-term cycling tests. The capacities delivered by the cell after 200 cycles were 707 and 410 mAh·g-1 at C/2 and 1C （1C = 1,675 mA·g-1）, respectively, maintaining the high Coulombic efficiency. The overall electrochemical response of this carbon as the sulfur matrix is among the best reported so far among the other biomass-derived carbons, probably because of the micro- and mesopore system formed upon activation.

关键词： activated carbon agricultural waste cherry stone sulfur composite lithium-sulfur batteries

Neoadjuvant therapy for resectable pancreatic ductal adenocarcinoma: The need for patient-centered research

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World Journal of Gastroenterology 2020年第4期26卷 375-382页

作者： Jordan M Cloyd Allan Tsung John Hays celia E Wills John FP Bridges Department of Surgery The Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Internal Medicine The Ohio State UniversityColumbusOH 43210United States College of Nursing The Ohio State UniversityColumbusOH 43210United States Department of Biomedical Informatics The Ohio State UniversityColumbusOH 43210United States

Pancreatic ductal adenocarcinoma is an aggressive cancer with high recurrence rates following surgical *** adjuvant chemotherapy improves survival,a significant proportion of patients are unable to initiate or complete all intended therapy following pancreatectomy due to postoperative complications or poor performance *** administration of chemotherapy prior to surgical resection is an alternative strategy that ensures its early and near universal delivery as well as improves margin-negative resection rates and potentially improves long-term survival *** therapy is increasingly being recommended to patients with pancreatic ductal adenocarcinoma,however,patient-centered research on its use is *** this review,we highlight opportunities to focus research efforts in the domains of patient preferences,patient-reported outcomes,patient experience,and *** research in these areas may identify relevant barriers and facilitators to the use of neoadjuvant therapy thereby increasing its utilization,improve shareddecision making for patients and providers,and optimize the experience of those undergoing neoadjuvant therapy.

关键词： Preoperative therapy Pancreatic ductal adenocarcinoma Quality of life Shared decision making Patient preferences

Analysis and Modeling of Slope Stability in the Three-Gorges Dam Reservoir (China)——The case of Huangtupo Landslide

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Journal of Mountain Science 2011年第2期8卷 166-175页

作者： R.COJEAN Y.J.ca Centre de Géosciences Mines-ParisTech Paris France Changjiang Institute of Survey Planning Design & Research CWRC Wuhan China

The water level in the Three Gorges Dam reservoir is expected to change between the elevations of 145 m and 175 m, as a function of the flood control implementation and the intensity of the annual flood. As a matter of fact, the hydraulical and mechanical loadings, related to the water level modifications, will result in alterations in the slope stability conditions. The town of Badong (Hubei), of 20 000 inhabitants, is one of the towns which was submerged by the impoundment of the reservoir. As a consequence, the new town of Badong was constructed on a nearby site which appeared to be partly an unstable site. A part of this site corresponds to an old landslide, the Huangtupo landslide, the base of which had to be submerged by the water of the reservoir. The analysis of the Huangtupo landslide, taking into account various events scenarios, drainage and reinforcement measures and monitoring devices, allows to illustrate the general process implemented all along the reservoir in order to mitigate the landslide hazard.

关键词：黄土坡滑坡水库蓄水边坡稳定性三峡大坝建模中国案例防洪功能

Metabolic alterations in cancer cells and therapeutic implications

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Chinese Journal of cancer 2011年第8期30卷 508-525页

作者： Naima Hammoudi Kausar Begam Riaz Ahmed1 celia Garcia- Prieto Peng Huang Department of Molecular Pathology The University of Texas MD Anderson Cancer Center Houston Texas 77030 USA The University of Texas Graduate School of Biomedical Sciences at Houston Houston Texas 77030 USA The Department of Health Disparities Research The University of Texas MD Anderson Cancer Center. Houston. Texas 77030. USA.

cancer metabolism has emerged as an important area of research in recent *** of the metabolic differences between cancer and normal cells and the underlying mechanisms will not only advance our understanding of fundamental cancer cell biology but also provide an important basis for the development of new therapeutic strategies and novel compounds to selectively eliminate cancer cells by targeting their unique *** article reviews several important metabolic alterations in cancer cells,with an emphasis on increased aerobic glycolysis (the Warburg effect) and glutamine addiction,and discusses the mechanisms that may contribute to such metabolic *** addition,metabolic alterations in cancer stem cells,mitochondrial metabolism and its influence on drug sensitivity,and potential therapeutic strategies and agents that target cancer metabolism are also discussed.

关键词：新陈代谢肿瘤细胞治疗细胞生物学药物敏感性正常细胞谷氨酰胺代谢变化