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Effect of long-term Helicobacter pylori infection on growth of children:a cohort study

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World Journal of Pediatrics 2016年第2期12卷 196-201页

作者： celebi kocaoglu Ahmet Ozel Mustafa Cayci Ece Selma Solak Department of Pediatrics Konya Education and Research Hospital42090 MeramKonyaTurkey Department of Pediatric Nephrology Konya Education and Research Hospital42090 MeramKonyaTurkey Department of Nuclear Medicine Konya Education and Research Hospital42090 MeramKonyaTurkey

Background:The effects of Helicobacter pylori(***)infection on growth are a controversial *** investigated the effects of long-term *** infection on height and weight in ***:A total of 200 children of 7-18 years old suffering from dyspeptic complaints were classified into two groups:*** positive and negative groups,*** the infection was impoved was followed up while performing urea breath test,and according to exposure time to the infection,the children were further divided into group 1(≤1.5 months),group 2(>1.5-≤6 months)and group 3(>6 months).Antropometric measurements were obtained and repeated every six ***:Mean growth velocity scores in the *** positive and negative groups were 0.49±3.85[95%confidence interval(CI):-0.21-1.18]and 1.98±4.42(95%CI:1-2.96),*** difference between both groups was statistically significant(P=0.012).Mean growth velocity scores in groups 1,2 and 3 were 0.96±3.84,0.16±4.51 and-0.85±3.09,*** growth velocity scores of group 3 were significantly lower than those of groups 0 and 1(P=0.005 and P=0.041).The mean weight scores in group 3 were similar to those in group 2,but the scores in group 3 were signifi cantly lower than those in group 1(-1.75±1.05,-1.21±1.37 and-0.88±1.49,respectively).Conclusion:As the duration of exposure is prolonged in children with *** infection,the negative effect of the infection on both height and weight is evident.

关键词： antropometry failure to thrive growth velocity Helicobacter pylori

Site dependent and spatially varying response spectra

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Earthquake Engineering and Engineering Vibration 2019年第3期18卷 497-509页

作者： Hakima Djilali Berkane Zamila Harichane Erkan celebi Sidi Mohammed Elachachi Geomaterials Laboratory Hassiba Benbouali University of Chlef Chlef 02180 Algeria Department of Civil Engineering Sakarya University Adapazari Turkey University of Bordeaux I2M GCE Department France

The goal of this study is to provide a stochastic method to investigate the eff ects of the randomness of soil properties due to their natural spatial variability on the response spectra spatial variation at sites with varying conditions. For this purpose, Monte Carlo Simulations are used to include the variability of both incident ground motion and soil parameters in the response spectra by mean of an appropriate coherency loss function and a site-dependent transfer function, respectively. The approach is built on the assumption of vertical propagation of SH type waves in soil strata with uncertain parameters. The response spectra are obtained by numerical integration of the governing equation of a single-degree-of-freedom (SDOF) system under non-stationary site-dependent and spatially varying ground motion accelerations simulated with non-uniform spectral densities and coherency loss functions. Numerical examples showed that randomness of soil properties signifi cantly aff ects the amplitudes of the response spectra, indicating that as the heterogeneity induced by the randomness of the parameters of the medium increases, the spectral ordinates attenuate.

关键词： response spectra randomness spectral density Monte Carlo

ENVIRONMENTAL PROPERTIES OF ENVIRONMENTALLY FRIENDLY CONSTRUCTION MATERIALS:RECYCLED LDPE COMPOSITES FILLED BY BLAST FURNACE DUST

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Journal of Green Building 2021年第3期16卷 135-153页

作者： Merve Tuna Kayili Gülser celebi Karabuk University Faculty of ArchitectureDepartment of ArchitectureKarabukTurkey Çankaya University Faculty of ArchitectureDepartment of Interior DesignAnkaraTurkey

This study focused on creating a sustainable composite material using blast furnace dust of the iron-steel industry and plastic wastes of the plastic industry in order to reduce the embodied energy of the material and generate more sustainable *** this study,varying amounts of blast furnace dust(BFD),which is the primary iron-steel industry waste and which is used as filler for recycled low-density polyethylene(LDPE),was mixed to create the composite *** embodied energy,emissions to water and air(volatile organic compounds)of BFD filled LDPE composites were *** was found that the composite materials had less embodied energy compared with polymer-based flooring materials such as epoxy,polyurethane(PU)and polyvinylchloride(PVC).In addition,it was determined that the composite material did not release emissions to water and have fewer total volatile organic compounds(TVOCs).These results showed that the produced composite material could be used in buildings as a sustainable floor coating material,thus saving raw materials and supporting indoor air quality and recycling.

关键词： LDPE composite blast furnace dust embodied energy TVOCs waste management

Magnetization of Gd diffused YBa_2Cu_3O_(7-x) superconductor:Experiment and theory

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Chinese Physics B 2013年第7期22卷 489-493页

作者： F. Inanir S. Yildiz K. Ozturk S. celebi Department of Physics Art and Science FacultyRecep Tayyip Erdogan University Department of Metallurgical and Materials Engineering Ahi Evran University Department of Physics Karadeniz Technical University

The magnetization of Gd diffused YBa2Cu3O7-x is measured by a vibrating sample magnetometer （VSM） at selected temperatures （5, 25, 50, 77 K）. The experimental results for the magnetization are analyzed in the critical state framework involving Kim-Anderson field dependence Jc（H）=Jc0/（1＋｜H｜/H0）n of critical current density and equilibrium magnetization M eq . It is found that the inclusion of the equilibrium magnetization becomes more important at higher temperatures. At 77 K, the shape of the isothermal M-H hysteresis curve is governed by the equilibrium magnetization. Some superconducting parameters are determined by fitting the calculated curves to the experimental data.

关键词： type-II superconductor YBCO surface effect equilibrium magnetization critical-state model

Effect of Solution and Calcination Time on Sol-gel Synthesis of Hydroxyapatite

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Journal of Bionic Engineering 2019年第2期16卷 311-318页

作者： Serbiilent Turk Ibrahim Altinsoy Gozde celebi Efe Mediha Ipek Mahmut Ozacar Cuma Bindal Biomedical Magnetic and Semi Conductive Materials Research Center(BIMAS-RC)Sakarya UniversityEsentepe CampusSakarya 54187Turkey Faculty of Engineerings Department of Metallurgy and Materials Engineering Sakarya UniversityEsentepe CampusSakarya 54187Turkey Science&Arts Faculty Department of ChemistrySakarya UniversitySakarya 54187Turkey

Nano-sized hydroxyapatite(HA)particles were synthesized by sol-gel through water and ethanol based mediums of phosphoric acid(H3PO4)and calcium hydroxide(Ca(OH)2)at pH=11 for different calcination time(1 h,2 h,4 h).The effects of calcination time and solution on the crystallinity,morphology and impurity phases of the HA nanoparticles were examined via Fourier Transform Infrared(FTIR),Scanning Electron Microscopy(SEM),Energy Dispersive X-ray Spectroscopy(EDS)and X-ray Diffraction(XRD).It was found that crystallite size and the fraction crystallinity of the synthesized samples increased with calcination *** to solution medium,only CaO as impurity was appeared in the water-based solvent,CaO and Ca(OH)2 impurities were appeared in the ethanol-based *** lowest crystallinity was 0.92 and the highest crystallinity was 1.73 respectively,depending on the process *** Ca/P atomic ratio closest to the bone was found as *** a result,the employed water-based sol-gel processes for 1 h calcination time was determined as the optimum for the formation of nano-sized HA powders using calcium hydroxide and phosphoric acid.

关键词： bioceramics hydroxyapatite calcination time XRD sol-gel

Verifying the accuracy of interlocking tables for railway signalling systems using abstract state machines

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Journal of Modern Transportation 2016年第4期24卷 277-283页

作者： Basri Tugcan celebi Ozgur Turay Kaymakci Department of Control and Automation Engineering Faculty of Electrical and Electronics Engineering Yildiz Technical University

Railway transportation system is a critical sector where design methods and techniques are defined by international standards in order to reduce possible risks to an acceptable minimum level. CENELEC 50128 strongly recommends the utilization of finite state machines during system modelling stage and formal proof methods during the verifi- cation and testing stages of control algorithms. Due to the high importance of interlocking table at the design state of a sig- nalization system, the modelling and verification of inter- locking tables are examined in this work. For this purpose, abstract state machines are used as a modelling tool. The developed models have been performed in a generalized structure such that the model control can be done automatically for the interlocking systems. In this study, NuSMV is used at the verification state. Also, the consistency of the developed models has been supervised through fault injection. The developed models and software components are applied on a real railway station operated by Metro Istanbul Co.

关键词： Model checking - Abstract state machines Interlocking

Risk factors and clinical responses of pneumonia patients with colistin-resistant Acinetobacter baumannii-calcoaceticus

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World Journal of Clinical Cases 2019年第10期7卷 1111-1121页

作者： Hande Aydemir Hande Idil Tuz Nihal Piskin Guven celebi Canan Kulah Furuzan Kokturk Department of Infectious Diseases and Clinical Microbiology Zonguldak Bulent Ecevit UniversityFaculty of MedicineZonguldak 67100Turkey Department of Microbiology Zonguldak Bulent Ecevit UniversityFaculty of MedicineZonguldak 67100Turkey Department of Biostatistics Zonguldak Bulent Ecevit UniversityFaculty of MedicineZonguldak 67100Turkey

BACKGROUND Nosocomial infections with carbapenem-resistant Acinetobacter baumanniicalcoaceticus complex(ABC)strains are great problem for intensive care *** strains can develop resistance to all the antibiotics *** resistance is common and colistin resistance is rare in our *** the risk factors for colistin resistance is important since colistin seems to be the only remaining therapeutic option for the patients with pneumonia due to extensively drug resistant ABC for our *** To investigate the comparison of clinical responses and outcomes between pneumonia patients with colistin-susceptible and-resistant Acinetobacter *** During the study period,108 patients with pneumonia due to colistin-susceptible strains and 16 patients with colistin-resistant strains were included *** variables were compared with the Mann-Whitney U test,and categorical variables were compared using Pearson’s chi-square test or Fisher’s Exact chi-square test for two groups.A binary logistic regression model was developed to identify the potential independent factors associated with colistin resistance in patients with colistin-resistant *** High Acute Physiology and Chronic Health Evaluation II scores(OR=1.9,95%CI:1.4-2.7;P<0.001)and prior receipt of teicoplanin(OR=8.1,95%CI:1.0-63.3;P=0.045)were found to be independent risk factors for infection with colistin-resistant Acinetobacter *** combinations of antibiotics including colistin,meropenem,ampicillin/sulbactam,amikacin and trimethoprim/sulfamethoxazole were used for the treatment of patients with colistin-resistant *** the median duration of microbiological cure(P<0.001)was longer in the colistin-resistant group,clinical(P=0.703),laboratory(P=0.277),radiological(P=0.551),microbiological response(P=1.000)and infection related mortality rates(P=0.603)did not differ between the two *** the patients with infections due to c

关键词： Acinetobacter baumannii Colistin Ventilator-associated pneumonia

Comparison of the effect of intravitreal bevacizumab and intravitreal fasudil on retinal VEGF,TNFα,and caspase 3 levels in an experimental diabetes model

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International Journal of Ophthalmology(English edition) 2014年第1期7卷 57-61页

作者： Fatih Celik Fatih Ulas Zeynep Gunes Ozunal Tulin Firat Serdal celebi Umit Dogan Department of Ophthalmology Faculty of MedicineAbant Izzet Baysal University Department of Medical Pharmacology Faculty of MedicineAbant Izzet Baysal University Department of Histology and Embryology Faculty of MedicineAbant Izzet Baysal University

AIM: To evaluate the influence of an intravitreal injection of bevacizumab and fasudil on the retinal vascular endothelial growth factor(VEGF),tumor necrosis factor alpha(TNFα),and caspase 3 levels in a diabetic rabbit model. · METHODS: The study included 6 healthy rabbits(Group 1),6 rabbits with experimentally induced diabetes mellitus(DM)(Group 2),7 rabbits with experimentally induced DM to which intravitreal bevacizumab was administered(Group 3),and 7 rabbits with experimentally induced DM to which intravitreal fasudil was administered(Group 4). An intravitreal injection of 1.25mg/50μL bevacizumab in the right eye of rabbits in Group 3 and an intravitreal injection of 0.0064mg/50μL fasudil in the right eye of rabbits in Group 4 were administered on day 21 after the induction of DM. The studied eyes of the rabbits were enucleated three days after the intravitreal injection. The TNFα,VEGF,and caspase 3 levels were determined using the ELISA method. · RESULTS: There was a statistically significant difference in the VEGF and caspase 3 levels between groups(P =0.005 and P =0.013,respectively),but the TNF α level did not differ significantly between groups(P = 0.792). It was found that VEGF levels were significantly lower in Group 1 and Group 3 than in Group 2 using the Mann-Whitney U test with the Bonferroni correction(P = 0.004 for both comparison). There was no statistically significant difference between other groups with regard to VEGF levels(the P value ranged between 0.015 and 0.886). Although the P values of the caspase 3 levels were 0.015 for Group 1 and Group 4,0.038 for Group 2and Group 3,and 0.018 for Group 3 and Group 4,these P values remained above the threshold P value of 0.0083,which was the statistically significant level for post hoc tests. ·CONCLUSION: An intravitreal injection of bevacizumab decreased both the VEGF level,which plays a role in angiogenesis,and the caspase 3 level,which plays a role in apoptosis. Although not as effective as bevacizum

关键词： bevacizumab caspase 3 experimental diabetes fasudil tumor necrosis factor alpha vascular endothelial growth factor

Relation of binge eating disorder with impulsiveness in obese individuals

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World Journal of Psychiatry 2017年第2期7卷 114-120页

作者： Cenk Ural Hasan Belli Mahir Akbudak Ali Solmaz Zuhal Dogan Bektas Fatih celebi Department of Psychiatry Health Sciences University Bagcilar Education And Research Hospital Department of Psychiatry Mardin State Hospital Department of General Surgery Health Sciences University Bagcilar Education And Research Hospital

AIM To investigate the levels of impulsiveness, and the relationship between the binge eating disorder(BED) and the levels of impulsiveness in obese *** Two hundred and forty-one obese patients who were included in the study and candidate for bariatric surgery(weight loss surgery) were clinically interviewed to identify the BED group, and patients were divided into two groups: Those with BED and those without BED. The comorbidity rate of groups was determined by using structured clinical interview for DSM-Ⅳ(SCID-Ⅰ). A sociodemographic data form including the story of previous psychiatric treatment, structured clinical interview for DSM-Ⅳ(SCID-Ⅰ), Beck Anxiety Inventory, Beck Depression Inventory(BDI) and Barratt Impulsiveness Scale-11 were applied to both of the *** In regard to 241 obese individuals included in the study, total score and score of attention subscale for BED(+) group were significantly high(P < 0.05). In addition, suicide attempt, story of psychiatric consultation, and score for BDI were again significantly high in the BED(+) group(P < 0.05).CONCLUSION In assessment of obese individuals, assessment of associated psychopathology such as impulsive characteristics and suicide attempt in addition to disrupted eating behaviors will allow to have a more extensive view.

关键词： Binge eating Obesity Impulsiveness