检索结果-南通市图书馆

除了缺乏以外:增加维生素K摄入量对骨和血管健康的潜在益处

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

除了缺乏以外:增加维生素K摄入量对骨和血管健康的潜在益处

Can DyeCycling break the photobleaching limit in single-molecule FRET?

作者： cees vermeer Martin J.Shearer Armin Zittermann Caroline Bolton-Smith Pawel Szulc Stephen Hodges Paul Walter Walter Rambeck Elisabeth StLcklin·Peter Weber 王劲 Maastricht大学生化系 St Thomas医院德国波恩大学 MRC Human Nutrition Research

关键词：维生素K γ-羧基谷氨酸骨质疏松症骨矿物质密度心血管病

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Nano Research 2022年第11期15卷 9818-9830页

作者： Benjamin vermeer Sonja Schmid NanoDynamicsLab Laboratory of BiophysicsWageningen UniversityStippeneng 46708WE WageningenThe Netherlands

Biomolecular systems,such as proteins,crucially rely on dynamic processes at the *** biomolecular nanodynamics is therefore key to obtaining a mechanistic understanding of the energies and molecular driving forces that controlbiomolecular ***-molecule fluorescence resonance energy transfer(smFRET)is a powerful technique to observe inreal-time how a single biomolecule proceeds through its functional cycle involving a sequence of distinct structural ***,this technique is fundamentally limited by irreversible photobleaching,causing the untimely end of the experiment andthus,a narrow temporal bandwidth of≤3 orders of ***,we introduce“DyeCycling”,a measurement scheme withwhich we aim to break the photobleaching limit in *** introduce the concept of spontaneous dye replacement bysimulations,and as an experimental proof-of-concept,we demonstrate the intermittent observation of a single biomolecule forone hour with a time resolution of ***,DyeCycling can provide>100-fold more information per singlemolecule than conventional *** discuss the experimental implementation of DyeCycling,its current and fundamentallimitations,and specific biological use *** its general simplicity and versatility,DyeCycling has the potential torevolutionize the field of time-resolved smFRET,where it may serve to unravel a wealth of biomolecular dynamics by bridgingfrom milliseconds to the hour range.

关键词： biomolecular dynamics single-molecule fluorescence resonance energy transfer(smFRET) photobleaching conformational changes single-molecule kinetics

Analysis of the influencing factors of PAEs volatilization from typical plastic products

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2018年第4期30卷 61-70页

作者： Weidong Chen Chenchen Chi Chen Zhou Meng Xia cees Ronda Xueyou Shen College of Environmental & Resource Sciences Zhejiang University Hangzhou 310058 China Philips Research Eindhoven High Tech Campus 45656 AE Eindhoven The Netherlands Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control Hangzhou 310058 China

The primary emphasis of this research was to investigate the foundations of phthalate（PAEs） pollutant source researches and then firstly confirmed the concept of the coefficient of volatile strength, namely phthalate total content in per unit mass and unit surface area of pollutant sources. Through surveying and evaluating the coefficient of volatile strength of PAEs from typical plastic products, this research carried out reasonable classification of PAEs pollutant sources into three categories and then investigated the relationship amongst the coefficient of volatile strength as well as other environmental factors and the concentration level of total PAEs in indoor air measured in environment *** obtained phthalate concentration results under different temperature, humidity,the coefficient of volatile strength and the closed time through the chamber experiment. In addition, this study further explored the correlation and ratio of influencing factors that affect the concentration level of total PAEs in environment chambers, including environmental factors, the coefficient of volatile strengths of PAEs and contents of total PAEs in plastic products. The research created an improved database system of phthalate the coefficient of volatile strengths of each type of plastic goods, and tentatively revealed that the volatile patterns of PAEs from different typical plastic goods, finally confirmed that the coefficient of volatile strengths of PAEs is a major factor that affects the indoor air total PAEs concentration, which laid a solid foundation for further establishing the volatile equation of PAEs from plastic products.

关键词： Phthalate esters Air The coefficient of volatile strength Typical plastic products The influencing factors

Distribution and dispersal pattern of clay minerals in surface sediments,eastern Beibu Gulf,South China Sea

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2012年第2期31卷 78-87页

作者： LI Jun GAO Jianhua WANG Yaping LI Yan BAI Fenglong cees Laban Qingdao Institute of Marine Geology Qingdao 266071China MLR Key laboratory of marine resources and environments Qingdao 266071China Ministry of Education Key Laboratory for Coast and Island Development Nanjing UniversityNanjing 210093China Joint Key Laboratory of Coastal Study(XMU&FJIO) Xiamen UniversityXiamen 361005China Deltares AL Utrecht 3508The Netherlands

Clay minerology of sediments are useful in determining distribution, sources and dispersal routes of fine-grained sediments. In the present paper, clay minerals of surface sediments throughout the eastern part of Beibu Gulf has been investigated to reveal sources and transport of detrital fine- grained sediments. Four distinct clay mineral suites were observed from cluster analysis of clay mineral compositions of the samples. From the distribution pattern of clay minerals, we conclude that kaolinte in the eastern gulf is mainly derived from South China Landmass; Smectite could not be transported mainly by surface current from north-western Hainan Island, and maybe minor portion of it from Red River; Illite is mainly transported by the currents fl＇om South China Sea. Chlorite has two sources, namely South China Sea and South China Landmass. The Zhujiang River derived sediments could not be one of the sources for the clay mineral here, because of very different composition and ratios. The distribution pattern of clay minerals in the eastern Beibu Gulf is mainly controlled by fine-grained sediment source and local currents. The Silt/Clay, Smectite/Kaolinte, and Smetite/（Chlorite＋Illite） ratios could be used as indicators of fine-grained sediment dispersal in the gulf.

关键词： clay minerals sediment source analysis sediment dispersal Beibu Gulf

From spatio-temporal landslide susceptibility to landslide risk forecast

在线全文

学校读者我要写书评

暂无评论

Geoscience Frontiers 2024年第2期15卷 220-235页

作者： Tengfei Wang Ashok Dahal Zhice Fang cees van Westen Kunlong Yin Luigi Lombardo Faculty of Engineering China University of GeosciencesWuhan 430074China Faculty of Geo-Information Science and Earth Observation(ITC) University of TwenteEnschedeAE 7500Netherlands Institute of Geophysics and Geomatics China University of GeosciencesWuhan 430074China

The literature on landslide susceptibility is rich with examples that span a wide range of ***,the component that pertains to the extension of the susceptibility framework toward space–time modeling is largely *** statement holds true,particularly in the context of landslide risk,where few scientific contributions investigate risk dynamics in space and *** manuscript proposes a modeling protocol where a dynamic landslide susceptibility is obtained via a binomial Generalized Additive Model whose inventories span nine years(from 2013 to 2021).For the analyses,the data cube is organized with a mapping unit consisting of 26,333 slope units repeated over an annual temporal unit,resulting in a total of 236,997 *** phase already includes several interesting modeling experiments that have rarely appeared in the landslide literature(e.g.,variable interaction plots).However,the main innovative effort is in the subsequent phase of the protocol we propose,as we used climate projections of the main trigger(rainfall)to obtain future estimates of yearly susceptibility *** estimates are then combined with projections of urban settlements and associated populations to create a dynamic risk model,assuming vulnerability=***,this manuscript presents a unique example of such a modeling routine and offers a potential standard for administrations to make informed decisions regarding future urban development.

关键词： Space-time statistics Dynamic landslide susceptibility Landslide risk Future projections

Algorithm-improved high-speed and non-invasive confocal Raman imaging of 2D materials

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2020年第3期7卷 620-628页

作者： Sachin Nair Jun Gao Qirong Yao Michael H.G.Duits cees Otto Frieder Mugele Physics of Complex Fluids MESA+Institute for NanotechnologyUniversity of Twente Physics of Interfaces and Nanomaterials MESA+ Institute for NanotechnologyUniversity of Twente Medical Cell Bio Physics Tech Med Centre University of Twente

Confocal Raman microscopy is important for characterizing 2 D materials, but its low throughput significantly hinders its applications. For metastable materials such as graphene oxide(GO), the low throughput is aggravated by the requirement of extremely low laser dose to avoid sample damage. Here we introduce algorithm-improved confocal Raman microscopy(ai-CRM), which increases the Raman scanning rate by one to two orders of magnitude with respect to state-of-the-art works for a variety of 2 D materials. Meanwhile, GO can be imaged at a laser dose that is two to three orders of magnitude lower than previously reported, such that laser-induced variations of the material properties can be avoided. ai-CRM also enables fast and spatially resolved quantitative analysis, and is readily extended to 3 D mapping of composite materials. Since ai-CRM is based on general mathematical principles, it is cost-effective, facile to implement and universally applicable to other hyperspectral imaging methods.

关键词： 2D materials graphene graphene oxide confocal Raman microscopy algorithm

Co-seismic Landslide Inventory and Susceptibility Mapping in the 2008 Wenchuan Earthquake Disaster Area,China

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Mountain Science 2013年第3期10卷 339-354页

作者： LI Wei-le HUANG Run-qiu TANG Chuan XU Qiang cees van WESTEN State key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of Technology Faculty of Geoinformation Science and Earth Observation (ITC) University of Twente

The Ms 8.0 May 12,2008 Wenchuan earthquake triggered tens of thousands of *** widespread landslides have caused serious casualties and property losses,and posed a great threat to post-earthquake reconstruction.A spatial database,inventoried 43,842 landslides with a total area of 632 km 2,was developed by interpretation of multi-resolution remote sensing *** landslides can be classified into three categories:swallow,disrupted slides and falls;deep-seated slides and falls,and rock *** correlation between landslides distribution and the influencing parameters including distance from co-seismic fault,lithology,slope gradient,elevation,peak ground acceleration(PGA) and distance from drainage were *** distance from co-seismic fault was the most significant parameter followed by slope gradient and PGA was the least significant one.A logistic regression model combined with bivariate statistical analysis(BSA) was adopted for landslide susceptibility *** study area was classified into five categories of landslide susceptibility:very low,low,medium,high and very high.92.0% of the study area belongs to low and very low categories with corresponding 9.0% of the total inventoried *** susceptible zones make up 4.2% of the area with 17.7% of the total *** rest of the area was classified into high and very high categories,which makes up 3.9% of the area with corresponding 73.3% of the total *** the susceptibility map can reveal the likelihood of future landslides and debris flows,and it is helpful for the rebuilding process and future zoning issues.

关键词： Wenchuan Earthquake Landslide Inventory Susceptibility mapping Logistic regression

THE SCIENCE AND TECHNOLOGY BACKYARD AS A LOCAL LEVEL INNOVATION INTERMEDIARY IN RURAL CHINA

在线全文

学校读者我要写书评

暂无评论

Frontiers of Agricultural Science and Engineering 2022年第4期9卷 558-576页

作者： Jinghan LI cees LEEUWIS Nico HEERINK Weifeng ZHANG Knowledge Technology and Innovation GroupWageningen University&ResearchWageningen 6706KNthe Netherlands Development Economics Group Wageningen University&ResearchWageningen 6706KNthe Netherlands College of Resources and Environmental Science China Agricultural UniversityBeijing 100193China College of Resources and Environment Anhui Agricultural UniversityHefei 230036China

Agricultural innovation can be described as a coevolutionary process of technological innovation,symbolic change,and social or institutional innovation,which relies on the interactions and collaboration between multiple *** view emphasizes the significance of innovation intermediaries in supporting the coevolution process of *** studies have provided evidence on how innovation intermediaries play roles in supporting the coevolution innovation process at a broader innovation system ***,little emphasis has been given to the role of innovation intermediaries in supporting the coevolution process of innovation at the community level in rural *** address this research gap,this paper offers a case study of a novel type of innovation support intervention designed to promote technical change at the community level,the Science and Technology Backyard(STB).The paper focuses on the efforts of a specific STB in Wangzhuang village to promote innovation in tillage methods in wheat *** aims was to examine the role of this newly emerging innovation support intervention in supporting the coevolution process of innovation at the community level,and compare the outcome of the coevolution process in the village with an STB to that in villages without an *** journey analysis is applied to understand the evolved intermediation roles in the innovation process,and multivariate regression analysis is employed to assess the outcome of the coevolution process in villages with and without an *** findings suggest that the roles of STBs have evolved from knowledge brokers to systemic innovation intermediaries that facilitate the coevolution process of innovation inside an STB *** has led to a higher adoption rate of improved technology,a better enabling environment for learning,and more effective institutional support in STB villages than in non-STB ***,the effect of support provided by a single STB on the coe

关键词： agricultural innovation coevolution community level innovation intermediaries Science and Technology Backyards(STBs)

Mapping uncovered a multi-phase arc-back-arc system in the southern Beishan during the Permian

在线全文

学校读者我要写书评

暂无评论

National Science Review 2023年第2期10卷 14-16页

作者： Tong Hong Gabriel S.Santos cees R.van Staal Wenhua Ji Shoufa Lin Department of Earth and Environmental Sciences University of Waterloo Geological Survey of Canada China Geological Survey Xi'an Centre School of Resources and Environmental Engineering Hefei University of Technology

The Central Asian orogenic belt(CAOB),surrounded by the Baltica and Siberia cratons to the north,and the Tarim and North China cratons to the south,records successive evolution cycles of subduction and accretion/collision from Neoproterozoic to the Paleozoic that consumed and eventually closed the Paleo-Asian Ocean[1].Tectonic models of the terminal orogenesis are contentious,with discussions ranging from the time and location of final closure of the Paleo-Asian Ocean to the regional context and setting of its various tectonic constituents.

关键词：