检索结果-南通市图书馆

新发现 2015年第1期 65-67页

作者： cecile Michaut 王师

这是个与众不同的实验室，但它仍然是个实验室。它的全名是“声学-音乐协调与研究研究所”，不过它的简称IRCAM似乎知名度更高。这是个探索明日之声的实验室，也是一个未来乐器的作坊。

关键词：单簧管实验室研究所知名度音乐乐器

Full Length Spine CT and MRI

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International Journal of Clinical Medicine 2020年第5期11卷 270-281页

作者： Tae-Keun Ahn Stephane Bourret Wendy Thompson cecile Roscop Thibault Cloché Jean-Charles Le Huec Department of Orthopedic Surgery CHA Bundang Medical Center CHA University Seongnam Republic of Korea Vertebra Spine Unit Polyclinique Bordeaux Nord Aquitaine Bordeaux France

Spine is a complex and long structure in the human body. Visualization of the spine is essential to treat and manage spine disease and commonly requires further imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI). In most clinical fields, spine CT and MRI examinations are focused on the region of interest. However, spine is composed of cervical, thoracic, lumbar, sacrum and coccyx and sometimes demands examination of entire structure as well as regional spine depending on disease, patient’s state and physician’s decision. This review considers the available literature to describe when and how full length spine evaluation by CT and MRI is applied according to each spinal disease such as spinal trauma, deformity, infection, axial spondyloarthropathy and metastatic tumor.

关键词： Full Length Spine CT Full Length Spine MRI Trauma Deformity Infection Axial Spondyloarthropathy Metastasis

国外城市促进清洁建造的理念实践及对中国的启示

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城乡建设 2021年第20期 76-77页

作者：侯静 cecile Faraud 中国建筑节能协会

一、清洁建造兴起的背景原因和必要性建筑群和基础设施共同构成的建成环境为人们提供了保护、连接以及重要的生活、工作、学习、休闲娱乐的空间。但与此同时,建成环境也是最大的温室气体排放源和空气污染的重要来源。研究显示,全球范围...

一、清洁建造兴起的背景原因和必要性建筑群和基础设施共同构成的建成环境为人们提供了保护、连接以及重要的生活、工作、学习、休闲娱乐的空间。但与此同时,建成环境也是最大的温室气体排放源和空气污染的重要来源。研究显示,全球范围内,房屋建筑建造和基础设施建设过程的温室气体排放占全球温室气体排放总量的23%以上(其中仅水泥和钢铁两种建材就分别占全球温室气体排放量的8%和7%)。除了温室气体排放带来的气候影响,

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γ-射线血管内照射治疗计划系统的研制

东南大学学报（自然科学版） 2002年第4期32卷 586-589页

作者：於文雪李松毅 Pascal Haigron 罗立民 Antoine Lucas cecile Moisan 东南大学生物科学与医学工程系南京210096 LaboratoireTraitementduSignaletdel’Image

介绍了研究开发的三维血管内照射治疗计划系统 .该治疗计划系统建立在三维医学图像和临床上常用的γ射线源基础之上 ,集成了放射源剂量学数据管理、三维图像处理、治疗计划设计、剂量分布计算与显示、治疗计划评估和打印输出等功能模块 ... 详细信息

介绍了研究开发的三维血管内照射治疗计划系统 .该治疗计划系统建立在三维医学图像和临床上常用的γ射线源基础之上 ,集成了放射源剂量学数据管理、三维图像处理、治疗计划设计、剂量分布计算与显示、治疗计划评估和打印输出等功能模块 .为了验证治疗计划的有效性 ,文中给出了 2组实验数据 ,一组是与GammaMed治疗计划系统的对比结果。

关键词：血管内照射治疗计划系统剂量分布计算三维图像处理冠状动脉粥样硬化性心脏病 γ-射线研制

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约会时尚聚光灯外的筑梦师

中国国家旅游 2014年第7期 74-79页

作者： Caroline Rousset-Johnson cecile Rogue

一片华丽褶皱的诞生在欧洲的顶级时装定制业界，Gerard Lognon的名字可谓家喻户晓。他并不是顶级服装设计师，但是他做着一件让所有顶级设计师为之倾倒的事——帮助他们将头脑中如梦如幻的漂亮褶皱变成现实。而对于我来说，最幸运的事... 详细信息

一片华丽褶皱的诞生在欧洲的顶级时装定制业界，Gerard Lognon的名字可谓家喻户晓。他并不是顶级服装设计师，但是他做着一件让所有顶级设计师为之倾倒的事——帮助他们将头脑中如梦如幻的漂亮褶皱变成现实。而对于我来说，最幸运的事情则是亲眼看到那些举世无双的褶皱是如何被制作出来的。

关键词：聚光灯服装设计师时尚褶皱时装

Skin sensitization using the refined myeloid U937 skin sensitization test

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Skin sensitization using the refined myeloid U937 skin sensi...

The safety and efficacy of palbociclib in older patients with advanced breast cancer in a real-world setting

中国毒理学会第六届全国毒理学大会

作者： cecile PIROIRD Fabien IBANEZ Julien FAUGERE Charles GOMES Silvia MARTINOZZI-TEISSIER Nathalie ALEPEE L’ Oreal Research Aulnay sous BoisFrance

＜正＞OBJECTIVE The aim of this study was to refine the prediction model to only give a binary Sensitizer（S）/Non-Sensitizer（IMS） call without impacting the predictive capacities of the MUSST. METHODS In the present Myeloid U937 Skin Sensitization Test（MUSST） test method,co-stimulatory molecule CD86 as a marker of cell activation is *** parallel,cell viability is assessed using propidium iodide *** parameters are measured by flow cytometry.208 substances with LLNA data were *** results on this set gave 92 S,56 NS predictions and 60 Inconclusive （INC）.Statistical methods based on a stacking scoring method were applied on raw data of these 60 INC in order to find additional rules to classify these substances into S or *** A combination of 6 rules was identified,that allows to classify the INC into the 2 classes "sensitizers and non-sensitizers". Application of the rules to the 48 ECVAM dataset submitted in 2009 show an overall accuracy of 92%with a sensitivity of 96%and a specificity of 86%.The predictive performances of the MUSST on the 208 substances with the optimized prediction model composed of the original prediction model and the additional 6 rules-based model show 84%concordance,87%sensitivity and 79%specificity against LLNA *** false negative are observed among the extreme and strong *** The prediction model of the MUSST classifies the substances as S or ***,it would be inappropriate to consider the MUSST assay as a stand-alone method for skin hazard characterization（CLP classification）. The MUSST test method is modeling the dendritic cell *** dendritic activation information is foreseen to play an important role in a future integrated approach for both hazard characterization and potency.

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Journal of Cancer Metastasis and Treatment 2022年第1期8卷 15-27页

作者： Etienne Gouton Louis Tassy Joëlle Micallef Amir Meskine Renaud Sabatier Maud cecile-Herry Cécile Braticevic Anthony Goncalves Frederic Viret Alexandre de Nonneville Coline Montegut Franck Rouby Frederique Rousseau Department of Medical Oncology Institut Paoli-CalmettesMarseille 13009France Aix-Marseille Univ CNRS U7258INSERM U1068Institut Paoli-CalmettesCRCMMarseille 13009France Department of Clinical Pharmacology Régional Center of Pharmacovigilance Marseille-Provence-CorseAssistance Publique-Hôpitaux de MarseilleAix-Marseille Univ.Neurosciences InstituteMarseille 13005France

Aims:Palbociclib has been approved in combination with endocrine therapy(ET)for hormone receptor-positive(HR+)/human epidermal growth factor receptor 2-negative(HER2-)advanced breast cancer(ABC),regardless of *** though ABC is one of the most prevalent cancers in older patients,very few patients≥65 years old were included in pivotal ***,the current study evaluated the safety and efficacy of palbociclib in“real-world”routine treatment of unselected older patients with HR+/***:Data were collected on patients>70 years old who were treated with palbociclib plus ET for HR+/HER2-ABC in our *** analyzed safety data(CTCAE v4.0 criteria)and outcomes,such as progression-free survival(PFS)and overall survival(OS),as well as any associations between main geriatric characteristics and our ***,we assessed safety at a national level by analyzing all palbociclib-related adverse events(AEs)reported in the French Pharmacovigilance Database(FPVD)during the same ***:From February 2016 to July 2019,52 patients were identified with a median age of 80.9 years,of whom 88%presented an *** most common grade 3-4 AE was neutropenia(64%).Median PFS and OS were nine months and not reached,*** FPVD reports 227 cases of palbociclib-related AEs,with older and younger patients sharing similar ***:Palbociclib is well tolerated in older patients with efficacy comparable to that in younger ***,the addition of palbociclib to ET should be evaluated individually in this older and frailer subgroup.

关键词： Advanced breast cancer palbociclib older patients tolerance efficacy pharmacovigilance

Phenotypic Characterization of Carbapenemase-Producing Enterobacteriaceae Strains in a Referral Teaching Hospital in Yaoundé, Cameroon

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Open Journal of Medical Microbiology 2023年第1期13卷 52-67页

作者： cecile Ingrid Djuikoue Paule Dana Djouela Djoulako Rodrigue Kamga Wouambo Charlène Nkouankou Tomi Christiane Possi Kiyang Murielle Chantale Tchitchoua Vynnie Manuella Nyatchoutou Blondelle Kitio Messeu Herman Koyouo Tagne Cedric Dylan Seugnou Nana Nadjia Benhamed Hortense Gonsu Kamga Benjamin D. Thumamo Pokam Faculty of Health Sciences Université des Montagnes Bangangté Cameroon Faculty of Medicine Sorbonne Université Paris France Division of Hepatology Department of Medecine II Leipzig University Medical Center Leipzig Germany University of Sciences and Technology Oran Algeria Bacteriology Unit University Teaching Hospital Yaounde Cameroon Department of Medical Laboratory Science Faculty of Health Sciences University of Buea Buea Cameroon

Background: Carbapenemase-producing Enterobacteriaceae (CPE) are an important and increasing threat to global health. They are nowadays more encountered routinely in hospitals and cause high morbidity and mortality due to limited therapeutic alternatives. This study sought to determine the prevalence of CPE in Yaoundé teaching hospital, Cameroon, and the associated risk factors. Materials and Method: To achieve this goal, a descriptive cross-sectional study coupled to an analytical component with consecutive collection of Enterobacteria strains was carried out during a three-month period (from 27th July to 24th October 2018) in the University Teaching Hospital of Yaoundé, Cameroon. The oxidase and biochemical identification tests using a miniaturized Api 20 E system were performed on colonies grown on Eosin Methylene Blue (EMB) medium and subcultured on nutrient agar. Drug susceptibility testing was carried out according to the Antibiogram Committee of the French Society of Microbiology (CA-SFM 2018.V.2.0). The detection of carbapenemase production was performed by the CA-SFM 2018 algorithm for the screening of carbapenemase-producing enterobacteriaceae and its classification by inhibitory synergy tests. Results: Out of the 104 isolates, Escherichia coli (50%) was the most prevalent species, followed by Klebsiella pneumoniae (37.5%) and Citrobacter frendii (12.5%). Drugs susceptibility patterns showed a high resistance to penicillins group (97.4% to amoxicillin), cephalosporins (68.4% to cefotaxim, 58.1% to cefixim, 60.7% to ceftazidim, 57.1% of cefoxitin) and aztreonam (55.7%). However, 11.9% carbapenems related resistance was noticed: 14.4% to imipenem, 13.8% to ertapenem and 7.5% to meropenem. Numerous co-resistance to quinolones (65.8%), fluoroquinolones (49.6%), aminoglycosides (49.6%) and cotrimoxazole (71.8%) were also observed. From 104 isolates, AmpC production represented 23.08% (25/104) and 36.54% (38/104) were ESBL-isolates. The ove

关键词： Enterobacteriaceae Antibiotics Carbapenemase Resistance