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Biochemical mechanisms in drug-induced liver injury:Certainties and doubts

World Journal of Gastroenterology 2009年第39期15卷 4865-4876页

作者： Ignazio Grattagliano Leonilde Bonfrate catia v diogo Helen H Wang David QH Wang Piero Portincasa Clinica Medica "A.Murri" Dipartimento di Medicina Interna e Medicina PubblicaUniversity of Bari Medical School Department of Zoology Center for Neurosciences and Cell BiologyUniversity of Coimbra Department of Medicine Liver Center and Gastroenterology DivisionBeth Israel Deaconess Medical CenterHarvard Medical School and Harvard Digestive Diseases Center

Drug-induced liver injury is a significant and still unresolved clinical problem.Limitations to knowledge about the mechanisms of toxicity render incomplete the detection of hepatotoxic potential during preclinical development.Several xenobiotics are lipophilic substances and their transformation into hydrophilic compounds by the cytochrome P-450 system results in production of toxic metabolites.Aging,preexisting liver disease,enzyme induction or inhibition,genetic variances,local O2 supply and,above all,the intrinsic molecular properties of the drug may affect this process.Necrotic death follows antioxidant consumption and oxidation of intracellular proteins,which determine increased permeability of mitochondrial membranes,loss of potential,decreased ATP synthesis,inhibition of Ca2+-dependent ATPase,reduced capability to sequester Ca2+ within mitochondria,and membrane bleb formation.Conversely,activation of nucleases and energetic participation of mitochondria are the main intracellular mechanisms that lead to apoptosis.Non-parenchymal hepatic cells are inducers of hepatocellular injury and targets for damage.Activation of the immune system promotes idiosyncratic reactions that result in hepatic necrosis or cholestasis,in which different HLA genotypes might play a major role.This review focuses on current knowledge of the mechanisms of drug-induced liver injury and recent advances on newly discovered mechanisms of liver damage.Future perspectives including new frontiers for research are discussed.

关键词：生化机制肝损伤药物性免疫系统激活肝细胞损伤毒性机制肝脏疾病抗氧化剂

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A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes

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World Journal of Gastroenterology 2013年第20期19卷 3007-3017页

作者： Ignazio Grattagliano catia v diogo Maria Mastrodonato Ornella de Bari Michele Persichella David QH Wang Adriana Liquori Domenico Ferri Maria Rosaria Carratù Paulo J Oliveira Piero Portincasa Section of Internal Medicine Department of Interdisciplinary MedicineUniversity of Bari70124 BariItaly Center for Neuroscience and Cell Biology Largo Marques de PombalUniversity of CoimbraP-3004-517 CoimbraPortugal Laboratory of Histology and Comparative Anatomy Department of Animal and Environmental BiologyUniversity of Bari70125 BariItaly Division of Gastroenterology and Hepatology Department of Internal MedicineEdward Doisy Research CenterSaint Louis University School of MedicineSaint LouisMO 63104United States Department of Pharmacology and Human Physiology University of Bari70124 BariItaly

AIM:To investigate the effectiveness of antioxidant compounds in modulating mitochondrial oxidative alterations and lipids accumulation in fatty hepatocytes.METHODS:Silybin-phospholipid complex containing vitamin E(Realsil) was daily administered by gavage(one pouch diluted in 3 mL of water and containing 15 mg vitamin E and 47 mg silybin complexed with phospholipids) to rats fed a choline-deprived(CD) or a high fat diet [20% fat,containing 71% total calories as fat,11% as carbohydrate,and 18% as protein,high fat diet(HFD)] for 30 d and 60 d,respectively.The control group was fed a normal semi-purified diet containing adequate levels of choline(35% total calories as fat,47% as carbohydrate,and 18% as protein).Circulating and hepatic redox active and nitrogen regulating molecules(thioredoxin,glutathione,glutathione peroxidase),NO metabolites(nitrosothiols,nitrotyrosine),lipid peroxides [malondialdehyde-thiobarbituric(MDA-TBA)],and pro-inflammatory keratins(K-18) were measured on days 0,7,14,30,and 60.Mitochondrial respiratory chain proteins and the extent of hepatic fatty infiltration were evaluated.RESULTS:Both diet regimens produced liver steatosis(50% and 25% of liver slices with CD and HFD,respectively) with no signs of necro-inflammation:fat infiltration ranged from large droplets at day 14 to disseminated and confluent vacuoles resulting in microvesicular steatosis at day 30(CD) and day 60(HFD).In plasma,thioredoxin and nitrosothiols were not significantly changed,while MDA-TBA,nitrotyrosine(from 6 ± 1 nmol/L to 14 ± 3 nmol/L day 30 CD,P vels increased significantly with ongoing steatosis.In the liver,glutathione was decreased(from 34.0 ± 1.3 to 25.3 ± 1.2 nmol/mg prot day 30 CD,P < 0.001,and 22.4 ± 2.4 nmol/mg prot day 60 HFD,P < 0.001),while thioredoxin and glutathione peroxidase were initially increased and then decreased.Nitrosothiols were constantly increas

关键词： Fatty liver Glutathione Lipid peroxidation Nitrosothiols Nitrotyrosine Thioredoxin

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A Pt/Mnv_(2)O_(6) nanocomposite for the borohydride oxidation reaction

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Journal of Energy Chemistry 2021年第4期30卷 428-436页

作者： Jadranka Milikic Marta Martins Ana S.Dobrota Gamze Bozkurt Gulin S.P.Soylu Ayse B.Yurtcan Natalia v.Skorodumova Igor A.Pasti Biljana Sljukic diogo M.F.Santos Faculty of Physical Chemistry University of BelgradeStudentski trg 12-1611158 BelgradeSerbia CeFEMA Instituto Superior TécnicoUniversidade de LisboaLisbonPortugal Project Coordination Implementation and Research Center Erzurum Technical UniversityErzurumTurkey Faculty of Engineering Chemical Engineering DepartmentIstanbul University-Cerrahpasa34320 AvcilarIstanbulTurkey Department of Chemical Engineering Atatürk UniversityErzurumTurkey Department of Materials Science and Engineering School of Industrial Engineering and ManagementKTH-Royal Institute of TechnologyBrinellvägen 2310044 StockholmSweden Department of Physics and Astronomy Uppsala UniversityBox 51675120 UppsalaSweden

Problems associated with carbon support corrosion under operating fuel cell conditions require the identification of alternative supports for platinum-based nanosized electrocatalysts.Platinum supported on manganese vanadate(Pt/Mnv_(2)O_(6))was prepared by microwave irradiation method and characterized using X-ray diffraction,Fourier-transform infrared spectroscopy,X-ray photoelectron spectroscopy,scanning electron microscopy with energy dispersive spectroscopy,and transmission electron microscopy.The borohydride oxidation reaction(BOR)on Pt/Mnv_(2)O_(6) was studied in highly alkaline media using voltammetry,chronoamperometry,and electrochemical impedance spectroscopy.BOR electrocatalytic activity of Pt/Mnv_(2)O_(6) was also compared with that of commercial Pt/C(46 wt%Pt)electrocatalyst.The apparent activation energy of BOR at Pt/Mnv_(2)O_(6) was estimated to be 32 k J mol^(-1) and the order of reaction to be 0.51,indicating that borohydride hydrolysis proceeds in parallel with its oxidation.Long-term stability of Pt/Mnv_(2)O_(6) under BOR typical conditions was observed.A laboratory-scale direct borohydride fuel cell assembled with a Pt/Mnv_(2)O_(6) anode reached a specific power of 274 W g^(-1).Experimental results on Pt/Mnv_(2)O_(6) were complemented by DFT calculations,which indicated good adherence of Pt to Mnv_(2)O_(6),beneficial for electrocatalyst stability.

关键词： Borohydride oxidation reaction Platinum-based electrocatalyst Manganese vanadate Density functional theory

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SUSTAINABLE DEvELOPMENT OF CROP-LIvESTOCK FARMS IN AFRICA

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Frontiers of Agricultural Science and Engineering 2021年第1期8卷 175-181页

作者： Mariana C.RUFINO Charles K.K.GACHENE Rodrigue v.C.diogo James HAWKINS Alice A.ONYANGO Ousmane M.SANOGO Ibrahim WANYAMA Gabriel YESUF David E.PELSTER Lancaster Environment Centre Lancaster UniversityLancasterLA14YQUK Department of Land Resource Management and Agricultural Technology University of NairobiNairobiP.O.Box 29053-00625Kenya Faculty of Agricultural Sciences University of ParakouParakouP.O.Box 123Benin International Livestock Research Institute(ILRI) NairobiP.O.Box 30709-00100Kenya Institut d'Economie Rurale SikassoBP 16Mali Agriculture and Agri-Food Canada 2560 Blvd HochelagaQuebec CityG1V 2J3Canada

Crop-livestock farms across Africa are highly variable due to in agroecological and socioeconomic factors,the latter shaping the demand and supply of livestock products.Crop-livestock farms in Africa in the 20-first century are very different from most mixed farms elsewhere in the world.African crop-livestock farms are smaller in size,have fewer livestock,lower productivity and less dependency on imported feed than farms in most countries of Europe,the Americas and the intensive agricultural systems of Asia.This paper discusses the role African crop-livestock farms have in the broader socio-agricultural economy,and how these are likely to change adapting to pressures brought on by the intensification of food systems.This intensification implies increasing land productivity(more food per hectare),often leading to more livestock heads per farm,producing fertilized feeds in croplands and importing feed supplements from the market.This discussion includes(1)the links between crop yields,soil fertility and crop-livestock integration,(2)the increasing demand for livestock products and the land resources required to meet to this demand,and(3)the opportunities to integrate broader societal goals into the development of crop-livestock farms.There is ample room for development of crop-livestock farms in Africa,and keeping integration as part of the development will help prevent many of the mistakes and environmental problems related to the intensification of livestock production observed elsewhere in the world.This development can integrate biodiversity,climate change adaptation and mitigation to the current goals of increasing productivity and food security.The inclusion of broader goals could help farmers access the level of finance required to implement changes.

关键词： finance integrate goals

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Transcriptome analyses of the Dof-like gene family in grapevine reveal its involvement in berry, flower and seed development

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Horticulture Research 2016年第1期3卷 124-133页

作者： Danielle Costenaro da Silva vítor da Silveira Falavigna Marianna Fasoli vanessa Buffon diogo Denardi Porto Georgios Joannis Pappas Jr Mario Pezzotti Giancarlo Pasquali Luís Fernando Revers Graduate Program in Cell and Molecular Biology Center for BiotechnologyUniversidade Federal do Rio Grande do SulPorto Alegre91501-970RSBrazil Dipartimento di Biotecnologie Universitàdegli Studi di VeronaVerona37134Italy Embrapa Uva e vinho Bento Gonçalves95701-008RSBrazil Embrapa Semiárido Petrolina56302-970PEBrazil Department of Cell Biology Universidade de BrasíliaBrasília70910-900DFBrazil Syngenta Seeds Ltda UberlândiaMG38407-049Brazil Modesto CA 95354USA

The Dof(DNA-binding with one finger)protein family spans a group of plant transcription factors involved in the regulation of several functions,such as plant responses to stress,hormones and light,phytochrome signaling and seed germination.Here we describe the Dof-like gene family in grapevine(vitis vinifera L.),which consists of 25 genes coding for Dof.An extensive in silico characterization of the vviDofL gene family was performed.Additionally,the expression of the entire gene family was assessed in 54 grapevine tissues and organs using an integrated approach with microarray(cv Corvina)and real-time PCR(cv Pinot Noir)analyses.The phylogenetic analysis comparing grapevine sequences with those of Arabidopsis,tomato,poplar and already described Dof genes in other species allowed us to identify several duplicated genes.The diversification of grapevine DofL genes during evolution likely resulted in a broader range of biological roles.Furthermore,distinct expression patterns were identified between samples analyzed,corroborating such hypothesis.Our expression results indicate that several vviDofL genes perform their functional roles mainly during flower,berry and seed development,highlighting their importance for grapevine growth and production.The identification of similar expression profiles between both approaches strongly suggests that these genes have important regulatory roles that are evolutionally conserved between grapevine cvs Corvina and Pinot Noir.

关键词： involvement organs assessed

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Dietary Omega-3 Fatty Acids Deficiency Affects the Glutamatergic Transport System in Rat Retina:Modulatory Effects after High Intraocular Pressure

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Food and Nutrition Sciences 2013年第9期4卷 195-201页

作者： Letícia v.Siqueira Eduardo P.Rico Mário C.Bulla Luciano Bellini Luiz C.L.Silveira Lúcia vinadé diogo O.Souza Júlia D.Moreira Biochemistry Department Basic Sciences of Health InstituteFederal University of Rio Grande do SulPorto AlegreBrazil Phy-siology Department Biological Science CenterFederal University of ParáBelémBrazil Master Graduation Program in Biological Sciences Campus Sao GabrielFederal University of Pampa—UNIPAMPASao GabrielBrazil Department of Nutrition Health Sciences CentreFederal University of Santa CatarinaCampus Universitário TrindadeFlorianópolisBrazil

Glutamate excitotoxicity has been postulated as a putative mechanism involved in the physiopathology of glaucoma, a disease that can cause retinal cell damage. Thus, the modulation of glutamatergic parameters is a putative therapeutic target to prevent excitotoxic retinal injury. Here, we investigated the effect of dietary omega-3 fatty acids (w3) in the retinal glutamate transport system in basal and ischemic conditions. Female Wistar rats were divided into two groups: w3 diet (w3 group) and w3 deficient-diet (D group). Their pups, at 60 days old, were used for the experiments. Retinal ischemia, a mechanism involved in the physiopathology of glaucoma, was induced by high intraocular pressure (HIOP, 140 180 mmHg for 45 min) to impair retinal blood flow. Analyses were performed 7 days after ischemia. The D group showed a decreased glutamate uptake in basal conditions and after HIOP when compared to the w3 group. After HIOP, there was a decrease in glutamate uptake in the D group that was not observed in the w3 group (p vels of GLT-1 compared to the D group in basal and ischemic conditions. After HIOP, EAAC1 was increased in both groups, while GLT-1 increased only in the D group, compared to basal levels. GLAST and EAAT5 presented no alterations. The modulation of the glutamatergic system by dietary w3 fatty acids points to a potential mechanism by which w3 PUFAs exert beneficial effects in the retina.

关键词： N-3 PUFAs Retina Ischemia HIOP Glaucoma Glutamate Transporters

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Evaluation of labial versus labio-inferior lines of osteosynthesis using 3D miniplate for fractures of anterior mandible:A finite element analysis with a pilot clinical trial

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Chinese Journal of Traumatology 2019年第5期22卷 261-269页

作者： Keerthana Ponvel Elavenil Panneerselvam Sasikala Balasubramanian Krishna Kumar Raja v.B. Department of Oral and Maxillofacial Surgery SRM Dental College and HospitalRamapuram CampusRamapuramChennai 600089Tamil NaduIndia

Purpose:The fractures of anterior mandible are subject to severe torsional forces due to muscles acting in opposite directions.3D miniplate has been suggested as a good alternative by some researchers.However,finite element model(FEM)studies indicate that labio-inferior positioning of two miniplates perpendicular to each other offers better stability as compared to labial positioning.This study aims at combining the advantages of a single 3D miniplate and labio-inferior positioning of two conventional miniplates,which was assessed by finite element analysis along with a pilot clinical trial.Methods:Two FEM models were created using CT data of a 24-year-old patient with Angie class I occlusion:control model with labial plating and study model with labio-inferior plating.The models were processed with MIMICS.(materialise,Leuven,Belgium),catia.(Dassault Systemes)and finite element analysis softwares.Parameters adopted for analysis were(1)displacement(mm)of fracture fragments during each screw fixation,(2)lingual splay and post fixation stability of fracture fragments with masticatory load,and(3)stress distribution(MPa)across fracture fragments.Moreover,a pilot clinical trial including five patients with anterior mandible fracture was conducted.The fractures were managed by intraoral open reduction and 3D miniplate fixation in labio-inferior position.Intraoperative interfragmentary gap,post fixation lingual splay and radiographic fracture union and complications were assessed clinically.Results:Labio-inferior plating demonstrated less displacement(mm)of fracture fragments during screw fixation(0.059 vs.0.079)as well as after application of masticatory load(1.805 vs.1.860).Negligible lingual splay and less stress distribution(MPa)across fracture fragments(1.860 vs.1.847)were appreciated in the study group as compared to control group.Clinical trial support the favorable outcome related to intraoperative and postoperative assessment parameters.Conclusion:FEM analysis and clinical trial reveal better results with labio-

关键词： Mandibular fractures Finite element analysis Osteosynthesis 3D miniplate

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Electrochemical Remediation of 17α-Ethinylestradiol

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Journal of Chemistry and Chemical Engineering 2013年第4期7卷 344-350页

作者： Femando Miguel de Amorim Lino diogo Cordeiro Dias Renata Crispim Batista Eric de Souza Gil Iranaldo Santos da Silva Lucio Angnes Faculty of Pharmacy Federal University of Goias Goiania 74605-220 Brazil Postgraduate Program in Environmental Engineering Federal University of Goias Goiania 74603-150 Brazil Institute of Chemistry University of Sao Paulo Sao Paulo 5509 Brazil

Technological development has led to the emergence of new substances with many different purposes generating a new profile of pollutants in waterways. Among these, endocrine disruptors, such as 17EE (17α-ethinylestradiol), are of great importance due to their wide application and harmful consequences to the environment, human health and animals. The inefficiency of most water treatment processes in withdrawing such substances poses a global concern for the development of effective and environmentally clean methods. The electrochemical remediation processes appear as a powerful and "green" alternative for waste removal of organic or inorganic pollutants from complex environments, such as geosphere and hydrosphere. The research focus in this field is mostly related to the optimization of electronic devices with higher (photo) catalytic efficiency, whereas the starting material remains based on metal and carbon conventional electrodes. In the present study, the anodic removal process of 17α-ethinylestradiol at carbon cardboards was investigated in stationary and hydrodynamic conditions. The influence of pH and applied potential were evaluated, always taking into account the transposition of scale and environmental aspects. Thus, the principle of hormone removal showed to be strictly related to such parameters. It was observed that mild alkaline medium favors the anodic oxidation, whereas neutral and mild acid ones lead to higher adsorption at carbon surface. Also, when the applied potential was higher than 1.25 v, the electrochemical oxidation rate increased, and the adsorption was decreased. Furthermore, the removal efficiency of 17EE showed to be lower, the flow rate was higher.

关键词：炔雌醇化学修复环境清洁内分泌干扰物物质构成阳极氧化污染物生成无机污染物

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Fungal diversity notes 1277-1386:taxonomic and phylogenetic contributions to fungal taxa

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Fungal Diversity 2020年第5期104卷 1-266页

作者： Hai-Sheng Yuan Xu Lu Yu-Cheng Dai Kevin D.Hyde Yu-He Kan Ivana Kušan Shuang-Hui He Ning-Guo Liu v.venkateswara Sarma Chang-Lin Zhao Bao-Kai Cui Nousheen Yousaf Guangyu Sun Shu-Yan Liu Fang Wu Chuan-Gen Lin Monika C.Dayarathne Tatiana Baptista Gibertoni Lucas B.Conceição Roberto Garibay-Orijel Margarita villegas-Ríos Rodolfo Salas-Lizana Tie-Zheng Wei Jun-Zhi Qiu Ze-Fen Yu Rungtiwa Phookamsak Ming Zeng Soumitra Paloi Dan-Feng Bao Pranami DAbeywickrama De-Ping Wei Jing Yang Ishara S.Manawasinghe Dulanjalee Harishchandra Rashika S.Brahmanage Nimali Ide Silva Danushka S.Tennakoon Anuruddha Karunarathna Yusufjon Gafforov Dhandevi Pem Sheng-Nan Zhang AndréL.C.Mde Azevedo Santiago Jadson diogo Pereira Bezerra Bálint Dima Krishnendu Acharya Julieta Alvarez-Manjarrez Ali H.Bahkali vinod K.Bhatt Tor Erik Brandrud Timur S.Bulgakov E.Camporesi Ting Cao Yu-Xi Chen Yuan-Yuan Chen Bandarupalli Devadatha Abdallah M.Elgorban Long-Fei Fan Xing Du Liu Gao Camila Melo Gonçalves Luis F.P.Gusmão Naruemon Huanraluek Margita Jadan Ruvishika S.Jayawardena Abdul Nasir Khalid Ewald Langer diogo X.Lima Nelson Correia de Lima-Júnior Carla Rejane Sousa de Lira Jian-Kui(Jack)Liu Shun Liu Saisamorn Lumyong Zong-Long Luo Neven Matočec M.Niranjan JoséRibamar Costa Oliveira-Filho viktor Papp Eduardo Pérez-Pazos Alan J.L.Phillips Peng-Lei Qiu Yihua Ren Rafael F.Castañeda Ruiz Kamal C.Semwal Karl Soop Carlos A.Fde Souza Cristina Maria Souza-Motta Li-Hua Sun Meng-Le Xie Yi-Jian Yao Qi Zhao Li-Wei Zhou CAS Key Laboratory of Forest Ecology and Management Institute of Applied EcologyChinese Academy of SciencesShenyang 110164People’s Republic of China University of the Chinese Academy of Sciences Beijing 100049People’s Republic of China School of Ecology and Nature Conservation Beijing Advanced Innovation Center for Tree Breeding By Molecular DesignBeijing Forestry UniversityBeijing 100083People’s Republic of China CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Centre of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand East and Central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanChina Ruđer BoškovićInstitute Bijenička cesta 5410000 ZagrebCroatia Faculty of Agriculture Natural Resources and EnvironmentNaresuan UniversityPhitsanulok 65000Thailand Department of Biotechnology School of Life SciencesPondicherry UniversityR.V.NagarKalapetPondicherry 605014India College of Biodiversity Conservation Southwest Forestry UniversityKunming 650224People’s Republic of China Department of Botany Govt.College UniversityKatchery RoadLahorePakistan State Key Laboratory of Crop Stress Biology in Arid Areas and College of Plant Protection Northwest A&F UniversityYanglingShaanxiPeople’s Republic of China Laboratory of Plant Pathology College of Plant ProtectionJilin Agricultural UniversityChangchun 130118Jilin ProvincePeople’s Republic of China Centro de Biociências Departamento de MicologiaUniversidade Federal de PernambucoCidade UniversitáriaAvenida da Engenharia s/nRecifePernambuco 50740-600Brazil Departamento de Ciências Biológicas Universidade Estadual de Feira de SantanaAv.Transnordestina s/nNovo HorizonteFeira de SantanaBA 44036-900Brazil L

This is the twelfth contribution to the Fungal Diversity Notes series on fungal taxonomy,based on materials collected from many countries which were examined and described using the methods of morphology,anatomy,and strain culture,combined with DNA sequence analyses.110 taxa are described and illustrated,including five new genera,92 new species,eight new combinations and other taxonomic contributions(one new sequenced species,one new host and three new records)which are accommodated in 40 families and 1 incertae sedis in Dothideomycetes.The new genera are Amyloceraceomyces,Catenuliconidia,Hansenopezia,Ionopezia and Magnopulchromyces.The new species are Amyloceraceomyces angustisporus,Amylocorticium ellipsosporum,Arthrinium sorghi,Catenuliconidia uniseptata,Clavulina sphaeropedunculata,Colletotrichum parthenocissicola,Coniothyrium triseptatum,Cortinarius indorusseus,C.paurigarhwalensis,C.sinensis,C.subsanguineus,C.xiaojinensis,Diaporthe pimpinel-lae,Dictyosporella guizhouensis,Diplodia torilicola,Fuscoporia marquesiana,F.semiarida,Hansenopezia decora,Helicoarcta-tus thailandicus,Hirsutella hongheensis,Humidicutis brunneovinacea,Lentaria gossypina,L.variabilis,Lycoperdon lahorense,L.pseudocurtisii,Magnopulchromyces scorpiophorus,Moelleriella gracilispora,Neodevriesia manglicola,Neodidymelliopsis salvia,N.urticae,Neoroussoella magnoliae,Neottiella gigaspora,Ophiosphaerella chiangraiensis,Phaeotremella yunnanensis,Podosphaera yulii,Rigidoporus juniperinus,Rhodofomitopsis pseudofeei,Russula benghalensis,Scleroramularia vermispora,Scytinopogon minisporus,Sporormurispora paulsenii,Thaxteriellopsis obliqus,Tomentella asiae-orientalis,T.atrobadia,T.atrocastanea,T.aureomarginata,T.brevis,T.brunneoflava,T.brunneogrisea,T.capitatocystidiata,T.changbaiensis,T.citri-nocystidiata,T.coffeae,T.conclusa,T.cystidiata,T.dimidiata,T.duplexa,T.efibulata,T.efibulis,T.farinosa,T.flavidobadia,T.fuscocrustosa,T.fuscofarinosa,T.fuscogranulosa,T.fuscopelliculosa,T.globospora,T.gloeocystidiata,T.griseocastanea,T.griseofusca,T.griseomarginata

关键词： 110 taxa Agaricomycetes Ascomycota Basidiomycota Mucoromycota New combinations New genera New species Phylogeny Taxonomy

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Fungal diversity notes 253-366:taxonomic and phylogenetic contributions to fungal taxa

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Fungal Diversity 2016年第3期78卷 1-237页

作者： Guo Jie Li Kevin D.Hyde Rui Lin Zhao Sinang Hongsanan Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Pablo Alvarado Genivaldo Alves-Silva Joseph F.Ammirati Hiran A.Ariyawansa Abhishek Baghela Ali Hassan Bahkali Michael Beug D.Jayarama Bhat Dimitar Bojantchev Thitiya Boonpratuang Timur S.Bulgakov Erio Camporesi Marcela CBoro Oldriska Ceska Dyutiparna Chakraborty Jia Jia Chen K.W.Thilini Chethana Putarak Chomnunti Giovanni Consiglio Bao Kai Cui Dong Qin Dai Yu Cheng Dai Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Eske De Crop Rafael J.v.De Oliveira Carlos Alberto Fragoso de Souza JoséIde Souza Bryn T.M.Dentinger Asha J.Dissanayake Mingkwan Doilom E.Ricardo Drechsler-Santos Masoomeh Ghobad-Nejhad Sean P.Gilmore Aristóteles Góes-Neto MichałGorczak Charles H.Haitjema Kalani Kanchana Hapuarachchi Akira Hashimoto Mao Qiang He John K.Henske Kazuyuki Hirayama Maria J.Iribarren Subashini C.Jayasiri Ruvishika S.Jayawardena Sun Jeong Jeon Gustavo H.Jerônimo Ana L.Jesus E.B.Gareth Jones Ji Chuan Kang Samantha C.Karunarathna Paul M.Kirk Sirinapa Konta Eric Kuhnert Ewald Langer Haeng Sub Lee Hyang Burm Lee Wen Jing Li Xing Hong Li Kare Liimatainen diogo Xavier Lima Chuan Gen Lin Jian Kui Liu Xings Zhong Liu Zuo Yi Liu J.Jennifer Luangsa-ard Robert Lücking H.Thorsten Lumbsch Saisamorn Lumyong Eduardo M.Leaño Agostina v.Marano Misato Matsumura Eric H.C.McKenzie Suchada Mongkolsamrit Peter E.Mortimer Thi Thuong Thuong Nguyen Tuula Niskanen Chada Norphanphoun Michelle A.O’Malley Sittiporn Parnmen Julia Pawłowska Rekhani H.Perera Rungtiwa Phookamsak Chayanard Phukhamsakda Carmen L.A.Pires-Zottarelli Olivier Raspé Mateus A.Reck Sarah C.O.Rocha AndréL.C.M.Ade Santiago Indunil C.Senanayake Ledo Setti Qiu Ju Shang Sanjay K.Singh Esteban B.Sir Kevin v.Solomon Jie Song Prasert Srikitikulchai Marc Stadler Satinee Suetrong Hayato Takahashi Takumasa Takahashi Kazuaki Tanaka Li Ping Tang Kasun M.Thambugala Donnaya Thanakitpipattana Michael K.Theodorou Benjarong Thongbai Tuksaporn Thummarukcharoen Qing Tian Saowaluck Tibpromma Annemieke State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesNo 31st West Beichen RoadChaoyang DistrictBeijing 100101People’s Republic of China Centre of Excellence in Fungal Research and School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia Department of Botany and Microbiology Faculty of ScienceSohag UniversitySohag 82524Egypt ALvALAB C/La Rochela nº47E-39012 SantanderSpain Micolab Programa de Pós-Graduação em Biologia de FungosAlgas e PlantasDepartamento de BotânicaUniversidade Federal de Santa CatarinaCampus Universitário TrindadeCEP:88040-900 FlorianópolisSanta CatarinaBrazil Department of Biology University of WashingtonBox 351800SeattleWA 98195-1800USA Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouPeople’s Republic of China National Fungal Culture Collection of India(NFCCI) Biodiversity and Palaeobiology GroupMACS’Agharkar Research InstituteG.G.Agarkar RoadPune 411004India PO Box 116 HusumWA 98623-0116USA Formerly Department of BotanyGoa UniversityGoaIndia No.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha 403108India *** 345 Shipwatch LaneHerculesCA 94547USA Microbe Interaction Laboratory(BMIT) BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoeKhlong LuangPathum Thani 12120Thailand Academy of Biology and Biotechnology Southern Federal UniversityRostov-on-Don 344090Rostov regionRussia A.M.B.Gruppo Micologico Forlivese BAntonio“Cicognani” Via Roma Forlì Italy 18 A.M.B.Circolo Micologico“Giovanni Carini”C.P.314BresciaItaly Societàper gli Studi Naturalistici della Romagna C.P.144Bagnacavallo

Notes on 113 fungal taxa are compiled in this paper,including 11 new genera,89 new species,one new subspecies,three new combinations and seven reference specimens.Awide geographic and taxonomic range of fungal taxa are detailed.In the Ascomycota the new genera Angustospora(Testudinaceae),Camporesia(Xylariaceae),Clematidis,Crassiparies(Pleosporales genera incertae sedis),Farasanispora,Longiostiolum(Pleosporales genera incertae sedis),Multilocularia(Parabambusicolaceae),Neophaeocryptopus(Dothideaceae),Parameliola(Pleosporales genera incertae sedis),and Towyspora(Lentitheciaceae)are introduced.Newly introduced species are Angustospora nilensis,Aniptodera aquibella,Annulohypoxylon albidiscum,Astrocystis thailandica,Camporesia sambuci,Clematidis italica,Colletotrichum menispermi,C.quinquefoliae,Comoclathris pimpinellae,Crassiparies quadrisporus,Cytospora salicicola,Diatrype thailandica,Dothiorella rhamni,Durotheca macrostroma,Farasanispora avicenniae,Halorosellinia rhizophorae,Humicola koreana,Hypoxylon lilloi,Kirschsteiniothelia tectonae,Lindgomyces okinawaensis,Longiostiolum tectonae,Lophiostoma pseudoarmatisporum,Moelleriella phukhiaoensis,M.pongdueatensis,Mucoharknessia anthoxanthi,Multilocularia bambusae,Multiseptospora thysanolaenae,Neophaeocryptopus cytisi,Ocellularia arachchigei,O.ratnapurensis,Ochronectria thailandica,Ophiocordyceps karstii,Parameliola acaciae,P.dimocarpi,Parastagonospora cumpignensis,Pseudodidymosphaeria phlei,Polyplosphaeria thailandica,Pseudolachnella brevifusiformis,Psiloglonium macrosporum,Rhabdodiscus albodenticulatus,Rosellinia chiangmaiensis,Saccothecium rubi,Seimatosporium pseudocornii,S.pseudorosae,Sigarispora ononidis and Towyspora aestuari.New combinations are provided for Eutiarosporella dactylidis(sexual morph described and illus trated)and Pseudocamarosporium pini.Descriptions,illustrations and/or reference specimens are designated for Aposphaeria corallinolutea,Cryptovalsa ampelina,Dothiorella vidmadera,Ophiocordyceps formosana,Petrakia echinata,Phragmoporthe conformis and Pse

关键词： Ascomycota Basidiomycota Neocallimastigomycota Oomycota.Zygomycota Phylogeny Taxonomy New genus New species

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