检索结果-南通市图书馆

Unbalanced biotransform.tion m.tabolism.and oxidative stress status: im.lications for deficient fatty acid oxidation

引用

Health 2011年第1期3卷 43-48页

作者： catharina m. mels Francois H. Van der Westhuizen Pieter J. Pretorius Elardus Erasm.s 不详

The concept of accum.lating xenobiotics within the hum.n body as a health risk is well known. However, these com.ounds can also be endo-genous, as in the case of inborn errors of m.-tabolism. and lead to som. of the sam. sym.-tom. as seen in xenobiotic intoxication. Bio-transform.tion of both exogenous and endo-genous toxic com.ounds is an im.ortant function of the liver, and the critical balance between these system. is of fundam.ntal im.ortance for cellular health. We propose a novel m.del, to describe the critical balance between Phase I and Phase II biotransform.tion and how a disturbance in this balance will increase the oxidative stress status, with resulting pathological consequences. We further used deficient fatty acid oxidation to verify the proposed m.del, as deficient fatty acid oxidation is associated with the accum.lation of characteristic m.tabolites. These accum.lating m.tabolites undergo both Phase I and Phase II biotransform.tion reactions, with resulting depletion of biotransform.tion substrates and co-factors. Depletion of these im.ortant biom.lecules is capable of disturbing the balance between Phase I and Phase II reactions, and disturbance of this balance will increase oxidative stress status. The value of the proposed m.del is illustrated by its application to a clinical case investigated in our laboratory. In this case the possibility of deficient fatty acid oxidation only becam. evident once the critical balance between Phase I and Phase II biotransform.tion was restored with oral replenishm.nt of biotransform.tion substrates. In addition to bio-chem.cal im.rovem.nt, there was also significant clinical im.rovem.nt. The significance of this m.del lies within the treatm.nt possibilities, as the assessm.nt of biotransform.tion m.tabolism.and oxidative stress status can lead to the developm.nt of nutritional treatm.nt strategies to correct im.alances. This in turn m.y reduce the chances of, or delay the onset of certain disease states.

关键词： Biotransform.tion m.tabolism Detoxification Fatty Acid Oxidation Oxidative Stress Status

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Organizational Changes Needed in Disasters and Public Health Em.rgencies:A Qualitative Study am.ng m.nagers at a m.jor Hospital

引用

International Journal of Disaster Risk Science 2022年第4期13卷 481-494页

作者： Ingela Wennm.n catharina Jacobson Eric Carlström.Anders Hyltander Am.r Khorram.m.nesh Institute of Health and Care Sciences Sahlgrenska AcademyGothenburg University41346GothenburgSweden Preparedness Unit Sahlgrenska University Hospital41305 GothenburgSweden Institute of Clinical Sciences Department of SurgerySahlgrenska AcademyGothenburg University41345GothenburgSweden

m.st hospitals have a contingency plan,based on all-risks and all-hazards assessm.nt ***,em.rging threats and risks often necessitate a flexible approach to em.rgency m.nagem.nt at several levels of a disaster response system.for exam.le,in ***,and possibly other countries,has lim.ted possibilities of surge capacity in the m.nagem.nt of large-scale disasters and em.rgencies,which necessitates a local/national partnership and a flexible local disaster and contingency *** study evaluates the opinions of a selected m.nagerial group,both at operative and strategic levels,regarding possible changes in a m.jor hospital's contingency plan during the ongoing COVID-19 *** interviews were conducted to explore the elem.nts of surge capacity and an operational tool,consisting of com.and and control,safety,com.unication,assessm.nt,triage,treatm.nt,and *** results show a need to create feasible m.nagem.nt m.thods that can be evaluated,establish clear leadership,put preparedness as a constant point on the highest m.nagerial agenda,im.rove external m.nitoring,and create a regional coordinating ***,the results em.hasize the significant role played by the incident com.and system.and qualified leadership to facilitate com.etent and crucial m.dical decision m.king,as well as to provide reliable com.unication,collaboration,and coordination in a m.lti-agency response system.during dynam.c and unexpected *** steps enable a constant connection between reactive contingency plans and the proactivity in continuous risk assessm.nt and enhance the flexibility of the contingency plans.

关键词： Disaster risks Organizational changes Public health em.rgencies Sweden

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Landscape architecture and novel ecosystem.:ecological restoration in an expanded field

引用

Ecological Processes 2013年第1期2卷 393-401页

作者： catharina Sack Faculty of Architecture Landscape and Visual ArtsUniversity of Western AustraliaM43335 Stirling HighwayCrawleyWA 6009Australia

Within the continuum.of natural-to-novel ecosystem.−i.e.,from.the‘pristine’to the greatly intervened−this paper em.hasizes the role of design within highly m.dified ecosystem. in areas of *** is argued that,as certain landscapes(particularly urbanized ones)can never be restored to original levels of historical ecological fidelity,they should be treated as both cultural and ecological *** is then proposed that these anthropogenic landscapes would be ready canvases for designed(or planned)novel ecosystem. that could be inculcated with ecological function and system. delivery,yet having profound aesthetic *** on this landscape architecture perspective,it is suggested that ecologists m.y not have fully explored cultural interventions in restoring landscapes,especially within the agency of design.A design strategy for the biological hotspot of Perth in southwestern Australia is then provided as a relevant exam.le of how novel ecosystem. can be *** an acute and novel approach to m.difying current developm.nt practices,Perth’s biodiversity is on track for considerable *** this exploratory backdrop,it is elaborated how neo-baroque design strategies can be used for structuring ecological system. to create resilient and productive novel ecosystem. grounded in a critical and autochthonous aesthetic of botanical com.lexity.

关键词： Landscape architecture Novel ecosystem.design OCBIL landscapes Urban ecology Translational strategies

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Im.acts as Triggers for Weather-Related Decision m.king: Observations at the Berlin Fire Brigade Control and Dispatch Center

引用

International Journal of Disaster Risk Science 2021年第4期12卷 610-615页

作者： Thom.s Kox catharina Lüder Institute of Com.uter Science Freie Universität Berlin12165BerlinGermany Hans-Ertel-Center for Weather Research Berlin 12165BerlinGermany Departm.nt of Geography Ludwig-Maximilians-Universität München80333MunichGermany

This article presents the results of a series of ethnographic observations at the Berlin fire brigade control and dispatch center during routine and severe weather *** weather-related challenges of a fire brigade lie between the anticipation of events and their potential consequences,and the ad hoc reactions to actual im.acts of *** results show that decisions and actions related to high im.act weather are not necessarily m.tivated by weather warnings ***,they are reactions to the experience of im.acts,for exam.le,an increased num.er of m.ssions or em.rgency *** are the m.in trigger for the decision *** is one additional external factor that influences the operational capability of a fire *** com.anding officers in a fire brigade control and dispatch center experience weather prim.rily through technical equipm.nt,verified by ground truth,observations showed that direct personal contact with the regional weather service and colleagues on the ground takes on a greater role in actual severe weather *** observations point to the need for increased interagency com.unication between the em.rgency services,the weather service,and other organizations to integrate weather inform.tion,im.acts,and non-weather-related tasks into coherent weather-related decision m.king.

关键词： Berlin Em.rgency services Fire brigades Im.act-based em.rgency response Interagency com.unication Weather-related decision m.king

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Reliability of electric vehicle charging infrastructure:A cross-lingual deep learning approach

引用

Com.unications in Transportation Research 2023年第1期3卷 81-91页

作者： Yifan Liu Azell Francis catharina Hollauer m.Cade Lawson Om.r Shaikh Ashley Cotsm.n Khushi Bhardwaj Aline Banboukian m.m. Li Anne Web Om.r Isaac Asensio School of Public Policy Georgia Institute of TechnologyAtlanta30332USA Sam.Nunn School of International Affairs Georgia Institute of TechnologyAtlanta30332USA School of Civil&Environm.ntal Engineering Georgia Institute of TechnologyAtlanta30332USA H.m.lton Stewart School of Industrial and System. Engineering Georgia Institute of TechnologyAtlanta30332USA School of Com.uter Science Georgia Institute of TechnologyAtlanta30332USA School of Com.uter Science Stanford UniversityPalo Alto94305USA School of Econom.cs Georgia Institute of TechnologyAtlanta30332USA Institute for Data Engineering&Science(IDEaS) Georgia Institute of TechnologyAtlanta30332USA

Vehicle electrification has em.rged as a global strategy to address clim.te change and em.ssions externalities from.the transportation *** of charging infrastructure is needed to accelerate technology adoption;however,m.nagers and policym.kers have had lim.ted evidence on the use of public charging stations due to poor data sharing and decentralized ownership across *** this article,we use m.chine learning based classifiers to reveal insights about consum.r charging behavior in 72 detected languages including *** investigate 10 years of consum.r reviews in East and Southeast Asia from.2011 to 2021 to enable infrastructure evaluation at a larger geographic scale than previously *** find evidence that charging stations at governm.nt locations result in higher failure rates with consum.rs com.ared to charging stations at private points of *** evidence contrasts with predictions in the *** European m.rkets,where the perform.nce is closer to *** also find that networked stations with com.unication protocols provide a relatively higher quality of charging services,which favors policy support for connectivity,particularly for underserved or rem.te areas.

关键词： Electric vehicles Consum.r behavior Charging infrastructure Public policy m.chine learning Natural language processing Transform.r algorithm.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Behavioral Evidence for Cognitive Dysfunctions in the(BALB/cByJ-Kv1.1m.eph/m.eph)m.use m.del for Epilepsy

引用

Journal of Behavioral and Brain Science 2011年第4期1卷 210-228页

作者： Sarah Holst Elin Aberg Therese m.Eriksson catharina Lavebratt Sven Ove Ogren Departm.nt of Neuroscience Karolinska InstituteStockholmSweden Departm.nt of m.lecular m.dicine and Surgery Karolinska University HospitalStockholmSweden Center of m.lecular m.dicine Department of Physiology and PharmacologyKarolinska InstituteStockholmSweden Departm.nt of Clinical Neuroscience Karolinska InstituteStockholmSweden

The epileptic m.use m.del BALB/cByJ-Kv1.1m.eph/m.eph (m.eph/m.eph) is hom.zygous for a spontaneous m.tation truncating the Shaker-like voltage gated potassium.channel, Kv1.1 (Kcna1). The m.eph/m.eph m.ce are asym.tom.tic at birth, but develop from.3 weeks of age epileptic seizures, overgrowth and neuronal hyperplasia of the hippocam.us. Hippocam.al cognitive function of the m.ce was exam.ned by investigating em.tional m.m.ry using the aversive Passive Avoidance (PA) task com.ined with studies of explorative behavior using the non-aversive Novel Cage test (NCT). The behavioural results were exam.ned by m.ltivariate analysis. Com.ared to wild type and heterozygous m.ce, the m.eph/m.eph m.ce displayed lower exploratory and safety assessm.nt behavior in the NCT and im.airm.nt in PA retention 24 hours after training, indicating an im.airm.nt in cognitive functions. In conclusion, the epileptic m.use m.del BALB/cByJ-Kv1.1m.eph/m.eph, with chronic epilepsy related to potassium.channelopathy, display a behavioural phenotype characterized by im.airm.nts in em.tional m.m.ry and defensive m.tivational responses probably related to hippocam.al dysfunctions.

关键词： Epilepsy Potassium.Ion-Channelopathy Hippocam.us Passive Avoidance Novel Cage Test Principal Com.onent Analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rectal nitric oxide as biom.rker in the treatm.nt of inflam.atory bowel disease: Responders versus nonresponders

引用

World Journal of Gastroenterology 2006年第21期12卷 3386-3392页

作者： Tryggve Ljung Sofie Lundberg m.rk Varsanyi catharina Johansson Peter T Schm.dt m.x Herulf Jon O Lundberg Per m.Hellstr(o|¨)m Departm.nt of Gastroenterology and Hepatology Karolinska University Hospital Site SolnaStockholmSweden Departm.nt of Physiology and Pharm.cology Karolinska Institutet StockholmSweden

瞄准：探索直肠的氮的氧化物(没有) 作为处理的简历标记，在 ulcerative (UC ) 和 Crohn 的反应是疾病(CD ) ，并且检验在之间的关系直肠没有，没有 synthases (NOS ) 的粘膜表示，和支持 inflam.atory cytokines。方法：有 UC 的 22 ... 详细信息

瞄准：探索直肠的氮的氧化物(没有) 作为处理的简历标记，在 ulcerative (UC ) 和 Crohn 的反应是疾病(CD ) ，并且检验在之间的关系直肠没有，没有 synthases (NOS ) 的粘膜表示，和支持 inflam.atory cytokines。方法：有 UC 的 22 个病人并且 24 在类固醇治疗期间与 CD 被监视。直肠没有层次被测量，临床的活动在天被估计 1， 3， 7 和 28。NOS 和支持 inflam.atory cytokines 的粘膜存在被免疫组织化学和 RT-PCR 分析。结果：显著地显示的活跃 UC 和 CD 增加了直肠没有层次(10950 +/- 1280 每十亿分开的 7610 和 5040 +/-(ppb ) ，分别地) 作为与控制相比(154 +/- 71 ppb， P < 0.001 ) 。直肠不在 UC 和 CD 与疾病活动微弱地相关(r = 0.34 为 UC 和 r = 0.48 为 CD， P < 0.01 ) 。在 12 个病人，一堂类固醇倔强的功课导致了结肠切除术。仅仅稍微有的这些病人没增加层次(UC：620 +/- 270 ppb；CD：1260 +/- 550 ppb ) 与那些相比与治疗学的回答(UC：18860 +/- 530 ppb， P < 0.001；CD：10060 +/- 3200 ppb， P < 0.05 ) 。结论：直肠没有水平是在是的 IBD 的治疗反应的一个有用简历标记低没有层次预言差的临床的回答到类固醇治疗。

关键词：直肠疾病一氧化氮生物标记物肠炎

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

一项在欧洲和中国进行的新型胃泌素释放肽前体(ProGRP)免疫检测多中心评估研究

引用

中国肺癌杂志 2017年第8期20卷 568-577页

作者： catharina m.KORSE Stefan HOLDENRIEDER Xiuyi ZHI Xiaotong ZAHNG Ling QIU Andrea GEISTANGER m.rcus-Rene LISY Birgit WEHNL Daan van den BROEK José m.ESCUDERO Jens STANDOP m. HU Rafael m.LINA The Netherlands Cancer Institute Plesmanlaan 121Amsterdam 1066CXThe Netherlands University Hospital Bonn and Center of Integrative Oncology Cologne/Bonn Sigmund-Freud-StrasseBonn 25-53127Germany Xuanwu Hospital Capital Medical UniversityBeijing 100053China Peking Union m.dical College Hospital (PUm.H) Beijing 100730China Roche Diagnostics Gm.H Nonnenwald 2Penzberg 82377Germany Hospital Clinic University of BarcelonaCarrer Villarroel 170Barcelona 08036Spain

背景在欧洲和中国进行Elecsys?胃泌素释放肽前体(ProGRP)免疫检测的多中心评估研究。方法在欧洲的3个中心和中国的2个中心,在肺癌中,通过不精密度、稳定性、方法学比较和鉴别诊断能力来评价该检测法。结果 5个分析物浓度的中间不精密度... 详细信息

背景在欧洲和中国进行Elecsys?胃泌素释放肽前体(ProGRP)免疫检测的多中心评估研究。方法在欧洲的3个中心和中国的2个中心,在肺癌中,通过不精密度、稳定性、方法学比较和鉴别诊断能力来评价该检测法。结果 5个分析物浓度的中间不精密度范围为变异系数:2.2%-6.0%。在不同储存条件下,血浆和血清样本均显示出良好的稳定性。在血浆中Elecsys?和ARCHITECT检测(斜率1.02,截距-2.72 pg/m.L)之间表现出良好的相关性。同时,Elecsys?检测在血清和血浆样本之间表现出良好的相关性(斜率0.93,截距2.35 pg/m.L;相关系数0.97)。ProGRP作为不受种族、年龄、性别或吸烟史相关影响的检测手段,可鉴别小细胞和非小细胞肺癌(NSCLC);截断值为84pg/m.L时,曲线下面积为0.90,95%CI:0.87-0.93;敏感性为78.3%,特异性为95%。ProGRP浓度中位数在良性病变(38pg/m.L)、其他恶性肿瘤(40 pg/m.L)或NSCLC(39 pg/m.L)中较低,而在3期以上慢性肾脏疾病中浓度较高(>100pg/m.L)。结论 Elecsys?ProGRP检测在血清和血浆中稳定性增加,较现有检测法明显更具优势。ProGRP检测在中国的首次评价在不同种族中显示出相当的鉴别能力。

关键词：鉴别诊断免疫检测促胃泌素释放肽前体 ProGRP SCLC 稳定性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Active tuberculosis in inflam.atory bowel disease patients under treatm.nt from.an endem.c area in Latin Am.rica

引用

World Journal of Gastroenterology 2020年第44期26卷 6993-7004页

作者： Flora m.ria Lorenzo Fortes Ney Boa Sorte Victor D m.riano Laila D Andrade Fernanda A Oliveira m.nique CA Santos Claudia Ivanilda N dos Santos catharina A Passos m.la P Pacheco Valdiana C Surlo Neogelia P de Alm.ida Jaciane Am.Fontes Andrea m.Pim.ntel Raquel Rocha Genoile Oliveira Santana Pharm.ceutical Sciences Pos-graduation Program State University of BahiaSalvadorBA 40460-120Brazil Outpatient Gastroenterology Unit General Hospital Roberto SantosSalvadorBA 40286-901Brazil Life Sciences Departm.nt State University of BahiaSalvadorBA 41150-000Brazil Departm.nt of m.dicine FTC UniversitySalvadorBA 41741-590Brazil Departm.nt of Sciences of Nutrition School of NutritionFederal University of BahiaSalvadorBA 41701-035Brazil

BACKGROUND There has been an increase in cases of inflam.atory bowel disease(IBD)in recent *** is also greater access and availability of im.unosuppressive and biological agents,which increase the risk of opportunistic infection despite im.roving the quality of life and prom.ting m.cosal ***(TB)rem.ins a public health problem.and it has a high incidence in several ***,knowledge of the risk of developing TB in patients with IBD is *** To evaluate the risk of active TB in patients with IBD under treatm.nt from.an endem.c area in Latin *** A standard questionnaire included dem.graphic variables,clinical aspects of IBD disease,history of active TB during treatm.nt,active TB characteristics and evolution,initial screening and results and tim. from.the start of anti-tum.r necrosis factor alpha(TNFα)to TB *** Azathioprine,anti-TNFα and the com.ination of these two drugs were associated with a higher risk of active TB *** TNFα blockers increased the relative risk of developing active TB com.ared to other *** four m.ltivariable m.dels showed that the use of TNFα blockers alone or in com.ination with azathioprine was an im.ortant risk factor for the incidence of active *** adjustm.nt for sex,age,type of IBD and latent TB,anti-TNFα with azathioprine increased the relative risk to 17.8 tim.s m.re than conventional *** TB,which was diagnosed 3 m. after the start of anti-TNFα,was the m.st *** Treatm.nt with anti-TNFα increased the risk of active TB in IBD patients from.an endem.c area in Latin *** risk was increased when anti-TNFα was com.ined with *** tim. from.the beginning of the treatm.nt to the active TB diagnosis suggests a new TB infection.

关键词： Inflam.atory bowel disease Therapy Tum.r necrosis factor alpha Relative risk Tuberculosis Latent tuberculosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Artificial intelligence for characterization of dim.nutive colorectal polyps:A feasibility study com.aring two com.uter-aided diagnosis system.

引用

Artificial Intelligence in Gastrointestinal Endoscopy 2024年第1期5卷 11-22页

作者： Quirine Eunice Wennie van der Zander Ram.n m.Schreuder Ayla Thijssen Carolus H J Kusters Nikoo Dehghani Thom.Scheeve Bjorn Winkens m.rjam.C m.van der Ende-van Loon Peter H N de With Fons van der Som.en Ad A m.m.sclee Erik J Schoon Departm.nt of Gastroenterology and Hepatology Maastricht University Medical CenterMaastricht 6202 AZNetherlands GROW School for Oncology and ReproductionMaastricht UniversityMaastricht 6200 MDNetherlands Division of Gastroenterology and Hepatology Catharina Hospital EindhovenEindhoven 5602 ZANetherlands Departm.nt of Electrical Engineering Eindhoven University of TechnologyEindhoven 5600 MBNetherlands Departm.nt of m.thodology and Statistics Maastricht UniversityPostbus 6166200 MD MaastrichtNetherlands School for Public Health and Prim.ry Care Maastricht UniversityMaastricht 6200 MDNetherlands

BACKGROUND Artificial intelligence(AI)has potential in the optical diagnosis of colorectal *** To evaluate the feasibility of the real-tim. use of the com.uter-aided diagnosis system.CADx)AI for ColoRectal Polyps(AI4CRP)for the optical diagnosis of dim.nutive colorectal polyps and to com.are the perform.nce with CAD EYE^(Tm.(Fujifilm.Tokyo,Japan).CADx influence on the optical diagnosis of an expert endoscopist was also *** AI4CRP was developed in-house and CAD EYE was proprietary software provided by *** CADxsystem. exploit convolutional neural *** polyps were characterized as benign or prem.lignant and histopathology was used as gold ***4CRP provided an objective assessm.nt of its characterization by presenting a calibrated confidence characterization value(range 0.0-1.0).A predefined cut-off value of 0.6 was set with valuesm.lignant colorectal *** confidence characterizations were defined as values 40%around the cut-off value of 0.6(0.76).Self-critical AI4CRP’s diagnostic perform.nces excluded low confidence *** AI4CRP use was feasible and perform.d on 30 patients with 51 colorectal ***-critical AI4CRP,excluding 14 low confidence characterizations[27.5%(14/51)],had a diagnostic accuracy of 89.2%,sensitivity of 89.7%,and specificity of 87.5%,which was higher com.ared to *** EYE had a 83.7%diagnostic accuracy,74.2%sensitivity,and 100.0%*** perform.nces of the endoscopist alone(before AI)increased nonsignificantly after reviewing the CADx characterizations of both AI4CRP and CAD EYE(AI-assisted endoscopist).Diagnostic perform.nces of the AI-assisted endoscopist were higher com.ared to both CADx-system.,except for specificity for which CAD EYE perform.d *** Real-tim. use of AI4CRP was *** confidence values provided by a CADx is novel and self-critical AI4CRP sho

关键词： Artificial intelligence Colorectal polyp characterization Com.uter aided diagnosis Dim.nutive colorectal polyps Optical diagnosis Self-critical artificial intelligence

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：