检索结果-南通市图书馆

Propranolol hydrochloride degradation using La@TiO_(2) functionalized with CMCD

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2022年第4期40卷 579-585,I0003页

作者： Gustavo lopes Colpani Vitor Follmann Santos Rubieli Carla Frezza Zeferino Micheli Zanetti Josiane Maria Muneron de Mello Luciano Luiz Silva Natan Padoin Regina de Fatima Peralta Muniz Moreira Márcio Antônio Fiori Cíntia Soaresc Post-Graduate Program in Technology and Innovation Management Community University of ChapecóRegionChapecó89809-900Brazil Department of Chemical Engineering Community University of ChapecóRegionChapecó89809-900Brazil Laboratory of Materials and Scientific Computing(LabMAC) Department of Chemical and Food EngineeringFederal University of Santa CatarinaFlorianópolis88040-900Brazil

Propranolol hydrochloride can be considered a persistent and bioaccumulative pharmaceutical in the *** drug and its by-products are potentially toxic and have adverse effects,since these compounds have been associated with endocrine-disrupting effects,reproductive deficiencies,embryo abnormalities and pericardial ***_(2)–La 0.05%–carboxymethyl-β-cyclodextrin(CMCD)nanoparticles were successfully prepared by a simple two-step method,which consists of sonification and *** characterization analyses reveal that lanthanum is dispersed on the semiconductor surface,probably forming Ti–O–La bonds,which can induce oxygen vacancies and surface defects that effectively restrain the recombination of photogenerated electron/holes *** efficiency of TiO_(2)–La 0.05%–CMCD samples in degradation of propranolol under UV-light irradiation is higher than that of pristine TiO_(2) within 20 min reaction,probably due to complex formation between theβ-blocker and the oligosaccharide,which allows us to propose a photocatalytic mechanism based on the formation of intermediates and competition of these compounds to the radicals and CMCD cavities.

关键词： TiO_(2) Lanthanum CMCD Propranolol Photocatalysis Functionalization

Comparative effects of insecticides with different mechanisms of action on Chrysoperla externa （Neuroptera＂ Chrysopidae）＂ Lethal, sublethal and dose-response effects

在线全文

学校读者我要写书评

暂无评论

Insect Science 2013年第6期20卷 743-752页

作者： Moises Joao Zotti Anderson Dionel Grutzmacher Isac Heres lopes Guy Smagghe UGent-Crop Protection Ghent Oost-Vlaanderen Belgium UFPel - Phytosanitary Pelotas RS Brazil

The comprehensive knowledge that the delayed systemic and reproduction side effects can be even more deleterious than acute toxicity, has caused a shift in focus toward sublethal effects assessment on physiology and behavior of beneficial insects. In this study, we assessed the risks posed by some insecticides with different mode of action through lethal and delayed systemic sublethal effects on the pupation, adult emergence, and repro- duction of the chrysopid Chrysoperla externa （Hagen, 1861; Neuroptera： Chrysopidae）, an important predator in pest biological control. The maximum field recommended dose （MFRD） and twice （2xMFRD） for chlorantraniliprole, tebufenozide, and pyriproxyfen were harmless to C. externa. In contrast, all the tested chitin synthesis inhibitors （CSIs） were highly detrimental to the predator, despite of their lack of acute lethal toxicity. There- fore, the safety assumed by using IGRs toward beneficial insects is not valid for chrysopids. Dose-response data showed that although all CSIs have a similar mechanism of action, the relative extent of toxicity may differ （novaluron 〉 lufenuron 〉 teflubenzuron）. For CSIs, the delayed systemic effects became obvious at adult emergence, where the predicted no observable effect dose （NOED） was 1/2 048 of the MFRD for novaluron （0.085 ng/insect）, and 1/256 of the MFRD for both lufenuron （0.25 ng/insect） and teflubenzuron （0.6 ng/insect）. Finally, this work emphasized the significance of performing toxicity risk assessments with an adequate posttreatment period to avoid underestimating the toxicities of insecticides, as the acute lethal toxicity assays may not provide accurate information regarding the long-range effects of hazardous compounds.

关键词： Chrysoperla externa dose-response effects ecotoxicology IGRs insecti-cide risk assessment topical application

Immediate bail-out TAP-stenting for the treatment of iatrogenic aortocoronary dissection involving left main bifurcation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2013年第2期10卷 202-204页

作者： Edmundo Patricio lopes Lao Shao-Ping Nie Chang-Sheng Ma Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Iatrogenic aortocoronary dissection is a rare but potentially disastrous complication of percutaneous coronary intervention. The left main dissection extending into distal bifurcation involving both the left anterior descending and left circumflex is a complex and vital complication, which is classified as Eshtehardi Type II dissection. We presented a case of iatrogenic left main coronary artery dissection with upcoming closure of both major branches, which was successfully managed by immediate bail-out TAP-stenting. The 77-year-old patient was discharged without any complication, and 1-year follow-up indicated stent patency and favorable clinical result. Immediate bail-out stenting is a feasible and reasonable initial management for this lethal complication.

关键词： Aorta Bail-out stenting Coronary artery Dissection Percutaneous coronary intervention

Peroxisome proliferator-activated receptors as targets to treat metabolic diseases:Focus on the adipose tissue,liver,and pancreas

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2023年第26期29卷 4136-4155页

作者： Henrique Souza-Tavares Carolline Santos Miranda Isabela Macedo lopes Vasques-Monteiro Cristian Sandoval Daiana Araujo Santana-Oliveira Flavia Maria Silva-Veiga Aline Fernandes-da-Silva Vanessa Souza-Mello Department of Anatomy Rio de Janeiro State UniversityRio de Janeiro 20551030Brazil Escuela de Tecnología Médica Facultad de SaludUniversidad Santo TomásOsorno 5310431Chile Departamento de Ciencias Preclínicas Universidad de la FronteraTemuco 4780000Chile

The world is experiencing reflections of the intersection of two pandemics:Obesity and coronavirus disease *** prevalence of obesity has tripled since 1975 worldwide,representing substantial public health costs due to its *** adipose tissue is the initial site of obesity *** excessive energy intake,it undergoes hyperplasia and hypertrophy until overt inflammation and insulin resistance turn adipocytes into dysfunctional cells that send lipotoxic signals to other *** pancreas is one of the organs most affected by *** lipotoxicity becomes chronic,there is an increase in insulin secretion by pancreatic beta cells,a surrogate for type 2 diabetes mellitus(T2DM).These alterations threaten the survival of the pancreatic islets,which tend to become dysfunctional,reaching exhaustion in the long *** for the liver,lipotoxicity favors lipogenesis and impairs beta-oxidation,resulting in hepatic *** silent disease affects around 30%of the worldwide population and can evolve into end-stage liver *** therapy for hepatic steatosis remains to be defined,peroxisome proliferator-activated receptors(PPARs)activation copes with T2DM *** PPARs are transcription factors found at the intersection of several metabolic pathways,leading to insulin resistance relief,improved thermogenesis,and expressive hepatic steatosis mitigation by increasing mitochondrial *** review aimed to update the potential of PPAR agonists as targets to treat metabolic diseases,focusing on adipose tissue plasticity and hepatic and pancreatic remodeling.

关键词： Obesity Insulin resistance Peroxisome proliferator-activated receptors Pancreas Hepatic steatosis Adipose tissue

Prediction of Pulmonary Arterial Pressure Level after Repair of Congenital Cardiac Communications and Discharge from the Hospital: Role of Down Syndrome and Early Postoperative Hemodynamics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Congenital Heart Disease 2022年第3期17卷 351-363页

作者： Eloisa Sassa Carvalho Maria Francilene SSouza Kelly Cristina O.Abud Claudia R.P.Castro Juliano G.Penha Ana Maria Thomaz Vanessa A.Guimaraes Antonio Augusto lopes Heart Institute(InCor) University of Sao Paulo School of MedicineSão PauloBrazil

Background:Postoperative pulmonary hypertension limits the success of surgical treatment in some patients with unrestrictive congenital cardiac *** patients at risk of developing postoperative pulmonary hypertension is important to individualize follow-up ***:We analyzed a prospective cohort of 52 pediatric patients(age 3 to 35 months)looking for perioperative predictors of mildly elevated pulmonary arterial pressure 6 months after surgery,defined as a systolic pressure greater than 30 mmHg by transthoracic *** corresponds to a mean pulmonary arterial pressure of>20 ***,echocardiographic and hemodynamic parameters were *** hemodynamics was assessed by directly measuring pulmonary and systemic arterial pressures using indwelling *** postoperative pulmonary hemodynamics was defined as the mean pulmonary/systemic mean arterial pressure ratio(PAP/SAP)obtained per patient during the first 6 h of postoperative ***:Among the factors that were investigated as possible predictors,perioperative hemodynamics and the presence of Down syndrome were initially selected using univariate analysis(p0.35 was 76%sensitive and 74%specific at predicting a systolic pulmonary arterial pressure of>30 mmHg 6 months after surgery(hazard ratio with 95%CI 8.972[2.428–33.158],p=0.002).Conclusion:The hypertensive early postoperative behavior of the pulmonary circulation was strongly but not exclusively associated with Down syndrome,and it was char

关键词： Pulmonary hypertension congenital heart disease Down syndrome pediatric cardiac surgery

Burden and factors associated with schistosomiasis and soil-transmitted helminth infections among school-age children in Huambo,Uige and Zaire provinces,Angola

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Diseases of Poverty 2022年第3期11卷 99-100页

作者： Adam W.Bartlett Jose C.Sousa-Figueiredo Roelofje Cvan Goor Paul Monaghan Warren Lancaster Rukaaka Mugizi Elsa P.Mendes Susana Vaz Nery Sergio lopes 不详 The Mentor Initiative 4Th Floor(South Suite)Burns HouseHarlands RoadHaywards HeathR161PGUK

Background:Schistosomiasis and soil-transmitted helminths(STHs)contribute high disease burdens amongst the neglected tropical diseases(NTDs)and are public health problems in *** study reports the prevalence,intensity and risk factors for schistosomiasis and STH infection in Huambo,Uige and Zaire provinces,Angola,to inform a school-based preventive chemotherapy ***:A two-stage cluster design was used to select schools and schoolchildren to participate in parasitological and water,sanitation and hygiene(WASH)surveys across Huambo,Uige,and Zaire ***-of-care circulating cathodic antigen and urinalysis rapid diagnostic tests(RDTs)were used to determine the prevalence of Schistosoma mansoni and ***,***-Katz was used to identify and quantify STH species and quantify and compare with RDTs for *** filtration was used to quantify and compare with RDTs for *** statistics were used for prevalence and infection intensity of schistosomiasis and STH *** of RDTs was assessed through specificity and Cohen’s Kappa agreement with microscopy.A multivariate regression analysis was used to determine demographic and WASH factors associated with schistosomiasis and STH ***:A total 575 schools and 17,093 schoolchildren participated in the schistosomiasis survey,of which 121 schools and 3649 schoolchildren participated in the STH *** prevalence of *** was 21.2%(municipality range 0.9–74.8%)and *** 13.6%(range 0–31.2%),with an overall prevalence of schistosomiasis of 31.4%(range 5.9–77.3%).Overall prevalence of Ascaris lumbricoides was 25.1%(range 0–89.7%),hookworm 5.2%(range 0–42.6%),and Trichuris trichiura 3.6%(range 0–24.2%),with an overall prevalence of STH infection of 29.5%(range 0.8–89.7%).Ecological zone and ethnicity were factors associated with schistosomiasis and STH infection,with older age and female sex additional risk factors for S

关键词： Schistosomiasis Soil-transmitted helminths Circulating cathodic antigen Rapid diagnostic test Water,sanitation and hygiene

Characteristics of Vertical Distributions of Fatty Acids in Surface Sediments of the Yellow Sea and East China Sea

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Ocean University of China 2018年第5期17卷 1123-1134页

作者： lopes Evanildo O. WANG Mengqi CHEN Ying YANG Guipeng DING Haibing College of Chemistry and Chemical Engineering Ocean University of ChinaQingdao 266100China Key Laboratory of Marine Chemistry Theory and Technology Ministry of EducationOcean University of ChinaQingdao 26610Q China China State Shipbuilding Corporation Electronics Technology Co.Ltd. Beijing 100015China Qingdao Collaborative Innovation Center of Marine Science and Technology Ocean University of ChinaQingdao 26610Q China Qingdao National Laboratory of Marine Science and Technology Qingdao 266100China

Fatty acids(FAs) in sediment collected from three different stations in the Yellow Sea and the East China Sea were analyzed for their distributions and to determine evidence of harmful algal blooms in the sediment *** diverse FAs were found in the Yellow Sea(YS) station,whereas in the two stations of the East China Sea(ECS) the FAs were more *** of some FA species in the two ECS stations displayed an occasional surge in their vertical *** highest concentration of FAs was found in the surface layer of station QT3(43.28 μg g^(-1)).Monounsaturated FAs were more susceptible to degradation compared to their saturated counterparts,and changes of 16:0,18:2 and 20:5 accounted for the most variability in total concentrations of FAs as those species made up most of the quantified *** origins of the major fraction of FAs were attributed to autotrophic sources,and bacterial FAs accounted for only a small fraction of the total FAs in the *** availability was a possible regulating factor controlling bacteria abundances in marine sediments in the ECS and the YS.A principal component analysis(PCA) was applied to analyze the FA dataset and to reveal the principal environmental factors that control the composition of FAs in the ***2,which explains 15% of the variance,was estimated to reflect the diagenetic effects on the FA compositional changes in sediments influenced by bacterial degradation.

关键词：表面沉积垂直分布东海黄海特征沉积控制营养物质可获得性

半固态加工Ti−Cu合金的显微组织和力学行为

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2022年第11期32卷 3578-3586页

作者： Kaio NIITSU CAMPO Caio Chaussêde FREITAS Éder Sócrates Najar lopes Suk-Chun MOON Rian DIPPENAAR Rubens CARAM School of Mechanical Engineering University of CampinasCampinasSPBrazil School of Mechanical MaterialsMechatronic and Biomedical EngineeringUniversity of WollongongWollongongNSWAustralia

研究触变成形Ti−Cu合金的力学性能。Ti−Cu(25%,27%,29%Cu,质量分数)锭的制备流程为:先进行电弧熔炼,再在950℃均匀化处理24 h,然后在900℃热锻,最后在1035℃热处理300 s后以8 mm/s的速度触变成形。结果显示,触变成形合金表现出良好的力... 详细信息

研究触变成形Ti−Cu合金的力学性能。Ti−Cu(25%,27%,29%Cu,质量分数)锭的制备流程为:先进行电弧熔炼,再在950℃均匀化处理24 h,然后在900℃热锻,最后在1035℃热处理300 s后以8 mm/s的速度触变成形。结果显示,触变成形合金表现出良好的力学强度,但其在拉伸载荷下的塑性一般,在压缩载荷下的塑性尚可。随着Cu含量的增加,包晶Ti_(2)Cu相(转变液相区)的体积分数增加,与α+Ti_(2)Cu相区(转变固相区)相比,其力学强度和塑性更低,导致合金的力学强度和塑性降低。这些结果表明,Ti−Cu合金的力学性能和半固态加工性之间的平衡主要取决于Cu含量。

关键词：半固态加工触变成形 Ti−Cu合金显微组织力学性能

Classification methodology for spare parts management combining maintenance and logistics perspectives

在线全文

学校读者我要写书评

暂无评论

Journal of Management Analytics 2018年第2期5卷 116-135页

作者： Catarina Teixeira Isabel lopes Manuel Figueiredo ALGORITMI Research Centre Department of Production and SystemsUniversity of MinhoGuimarãesPortugal

Spare parts management is a function of maintenance management that aims to support maintenance activities,giving real-time information on the available quantities of each spare part and adopting the inventory policies that ensure their availability when required,minimizing *** classification of spare parts is crucial to control the vast number of parts that have different characteristics and *** parts management involves mainly two areas,maintenance and ***,the integration of both input information is recommended to make *** paper presents a multicriteria classification methodology combining maintenance and logistics perspectives that intends to differentiate and group spare parts to,subsequently,define the most appropriate stock management policy for each *** methodology was developed based on a case study carried out in a multinational manufacturing company and is intended to be included in its computerized maintenance management system to support decision-making.

关键词： criticality maintenance management multi-criteria classification spare parts management