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CLT Fabricated with Gmelina arborea and Tectona grandis Wood from Fast-Growth Forest Plantations: Physical and Mechanical Properties

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Journal of Renewable Materials 2022年第1期10卷 1-17页

作者： Freddy Munoz carolina Tenorio Roger Moya Angel Navarro-Mora Escuela de Ingenieria Forestal Instituto Tecnologico de Costa RicaCartago159-7050Costa Rica Escuela de Ingenieria en Construccion Instituto Tecnologico de Costa RicaCartago159-7050Costa Rica

Fabrication and use of Cross Laminated Timber(CLT)using tropical woods is still limited at *** objective of the present study aims to determine the possibility of using CLT panels of 3 and 5 layers,fabricated withTectona grandis and Gmelina arborea wood using adhesive of isocyanate polymer emulsion system catalyzed with polymeric ***,water absorption,density,flexure test,compression and glue-line shear were evaluated using ANSI/APA PRG320-2012 ASTM D198 and ASTM D4761 *** results showed that CLT panels of *** presented higher values of density,less water absorption and lower delamination,with no evident differences between the CLT of 3 and 5 *** high density of *** resulted in higher values of the mechanical *** flatwise and edgewise flexure tests in 5-layer CLT panels of both species pre-sented higher values of bending stiffness compared to those of 3-layer CLT *** the bending stress values in 3-layer CLT panels were higher than for 5-layer CLT *** for shear stress in bending flatwise,in both species,3-layer CLT surpassed 5-layer CLT panels,but in the edgewise test no differences were *** MOE and Fc in the compression test were superior in relation to the edgewise *** and Fc in compres-sion flatwise in 3-layer CLT was greater than in 5-layer CLT in both species,but edgewise these values were higher in 5-layer CLT *** most common failures were stress and delamination in the flexure test,whereas in the compression test these were:shearing,splitting and *** the glue-line shear test no differences were observed between CLT panels of 3 and 5 layers for both species.

关键词： Structural elements sustainable material building material tropical wood wood of plantation

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Are the cerrado and the seasonal forest woody floras assembled by different processes despite their spatial proximity?

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Journal of Plant Ecology 2018年第5期11卷 740-750页

作者： Raquel carolina Miatto Marco Antonio Batalha Department of Botany Federal University of São CarlosPO Box 67613565-905São CarlosBrazil Department of Biology University of São Paulo14040-901Ribeirão PretoBrazil

Aims The Brazilian cerrado occupies land that could be occupied by seasonal forest,given current climatic conditions and their spatial *** has been identified as one of the main determinants of cerrado and forest *** tested whether cerrado and seasonal forest woody floras were assembled by different *** postulated that soil nutrient availability would account for dif-ferences in the functional and phylogenetic structure of the cerrado and the seasonal *** In 1005×5 m plots distributed along cerrado and seasonal forest patches in south-eastern Brazil,we sampled five individuals with a basal diameter≥3 cm from 127 species and measured seven of their functional traits(plant height,basal area,tortuosity,leaf size,specific leaf area,leaf dry matter content,and leaf toughness).We constructed a phylogenetic tree and calculated the pairwise mean functional-phy-logenetic distances(MFPDs),an approach that accounts for functional and phylogenetic information both separately and *** also sampled soils to a depth of 5 cm in each plot and had their chem-ical and physical properties *** related the MFPD to soil properties and compared MFPD between cerrado and forest *** Findings Phylogenetic distances were higher than functional distances in both cerrado and seasonal forest communities,suggesting trait convergence in both *** of the importance given to functional or phylogenetic information,most of the com-munities in the cerrado and in the seasonal forest fell within the null expectation,implying either that multiple assembly processes can occur simultaneously along the gradient of soil fertility,or that not all important traits were *** was related to soil nutrient status when only functional distances were *** this case,MFPD was lower in the cerrado than in the forest,indi-cating that soil nutrient availability influenced plant traits,with the low-nutrient soils in

关键词： competition functional traits environmental filter nutrient limitation phylogeny savanna

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Convergent pathways of the gut microbiota–brain axis and neurodegenerative disorders

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Gastroenterology Report 2022年第1期10卷 90-107页

作者： carolina Gubert Juciano Gasparotto Livia H.Morais Florey Institute of Neuroscience and Mental Health Melbourne Brain CentreUniversity of MelbourneParkvilleVictoriaAustralia Instituto de Ciencias Biomedicas Universidade Federal de AlfenasRua Gabriel Monteiro da SilvaAlfenasMinas GeraisBrasil Division of Biology&Biological Engineering California Institute of TechnologyPasadenaCAUSA

Recent research has been uncovering the role of the gut microbiota for brain health and *** studies highlight the role of gut microbiota on regulating brain function and behavior through immune,metabolic,and neuronal *** this review we provide an overview of the gut microbiota axis pathways to lay the groundwork for upcoming sessions on the links between the gut microbiota and neurogenerative *** also discuss how the gut microbiota may act as an intermediate factor between the host and the environment to mediate disease onset and *** on the current literature,we further examine the potential for different microbiota-based therapeutic strategies to prevent,to modify,or to halt the progress of neurodegeneration.

关键词： gut microbiota-brain axis neurodegeneration inflammation microbial metabolism gut microbiota

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Variable retention harvesting: conceptual analysis according to different environmental ethics and forest valuation

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Ecological Processes 2019年第1期8卷 485-491页

作者： Leonardo Galetto carolina Torres Guillermo J.Martínez Pastur Departamento de Diversidad Biológica y Ecología FCEFyNUniversidad Nacional de Córdoba(UNC)Vélez Sarsfield 16115000 CórdobaArgentina Instituto Multidisciplinario de Biología Vegetal(IMBIV) Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Vélez Sarsfield 16115000 CórdobaArgentina Centro Austral de Investigaciones Científicas(CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Houssay 2009410 UshuaiaTierra del FuegoArgentina.

Background:Conceptual clarity is important to attain precise communication of scientific knowledge and to implement appropriate technological and policy *** concepts referring to forest management are widely used by decision-makers,regardless of their *** the scientific and methodological issues of forestry practices are frequently discussed in the literature,their normative dimensions are rarely ***,linguistic uncertainty increases when different environmentally ethical perspectives and ways of valuing forests are *** objective was to compare different conceptualizations on the silvicultural systems suggested for forest management and the implications they have for *** have conceptually contrasted highintensity forestry practices with variable retention harvesting,considering different environmentally ethical perspectives and forest valuation ***:Clear boundaries between clear-cutting,selective logging,and variable retention harvesting can be evidenced when different ethical points of view and alternatives in the human-nature relationships are *** have found a variety of definitions of variable retention harvesting that can be analyzed under different ethical *** contrasting views on variable retention harvesting can be evidenced if nature is considered to be purely at human’s service or if it is conceptualized as humans co-inhabiting with *** latter position implies that the maintenance of ecological,evolutionary,and historical processes supported by unmanaged forest stands is a crucial step for forest management proposals based on variable retention ***:Forestry practices that are focused on forest yields and that misinterpret functional uncertainty of forest functioning would be ***,forestry with variable retention harvesting could imply good yields with reasonable conservation management in some contexts,while it could be unacce

关键词： Environmental ethical perspectives Consequentialism Deontological ethics Virtue ethics Policy options for forest and biocultural conservation

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Designing Cyclopentapeptide Inhibitor of Neuraminidase H5N1 Virus Through Molecular and Pharmacology Simulations

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Tsinghua Science and Technology 2015年第5期20卷 431-440页

作者： Usman Sumo Friend Tambunan Arli Aditya Parikesit Yossy carolina Unadi Djati Kerami Bioinformatics Research Group Department of ChemistryFaculty of Mathematics and ScienceUniversity of Indonesia Mathematics Computation Research Group Department of MathematicsFaculty of Mathematics and ScienceUniversity of Indonesia

Highly Pathogenic Avian Influenza（HPAI） H5N1 has attracted much attention as a potential pandemic virus in humans, which makes death inevitable in humans. Neuraminidase（NA） has an important role in viral replication. Thus, it is an attractive target when designing anti-influenza virus drug. However, evolving viruses cause some anti-viral drugs to be ineffective, as they show resistance to them. Selection of peptides as drug candidates is important for the peptide-receptor activity and good selectivity. Cyclic bonds in the peptide ligand design aim to improve the stability of the system and remove the obstacles in drug metabolism. The design is based on the polarity of the ligand and amino acid residues in the active site of NA. The results are 4200 cyclic pentapeptides as potential lead compounds. Docking simulations were conducted using MOE 2008.10 and were screened based on the value of the binding energy（？Gbinding）. ADME-Tox prediction assay was conducted on the selected ***- and inter-molecular interactions, as well as changes in the form of bonds, were tested by molecular dynamics simulations at temperatures of 310 K and 312 K. The results of the docking simulations and toxicity prediction assay show that there are two ligands that have a residual interaction with the target protein： CLDRC and CIWRC. These two ligands have ？Gbindingvalues of –40.5854 and –39.9721 kcal/mol（1 kcal/mol = 4.18 k J/mol）. These ligands are prone to be mutagenic and carcinogenic, and they have a good oral bioavailability. The results show that the molecular dynamics of both ligand CLDRC and CIWRC are more feasible at the temperature of 312 K. At the end,both CIWRC and CLDRC ligands can be used as the drug candidates against H5N1 virus.

关键词： H5N1 neuraminidase cyclical pentapeptide molecular docking molecular dynamics

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