检索结果-南通市图书馆

f.nctionalization of.AuMSS nanorods towards more ef.ective cancer therapies

Nano Research 2019年第4期12卷 719-732页

作者： carolina f. rodrigues Telma A. Jacinto Andre f. Moreira Elisabete C. Costa Sonia P. Miguel Ilidio J. Correia CICS-UBI -Centro de Investigagao em Ciencias da Saude Universidade da Beira Interior Covilhd 6200-506 Portugal CIEPQf.- Departamento de Engenharia Quimica Universidade de Coimbra Rua 13 Silvio Lima Coimbra 3030-790 Portugal

The applicatio n of.nano particles as selective drug delivery platf.rms arises as one the most promising therapeutic strategies in the biomedical f.eld. Such systems can encapsulate drugs, prevent its premature degradation, transport and promote the drugs specif.c delivery to the target site. Among the dif.erent nanostructures, gold-core mesoporous silica shell (AuMSS) nanorods have been one of.the most explored due to their unique physical and chemical properties. The mesoporous silica biocompatibility, high surf.ce area that can be easily f.nctionalized, tubular pores that can store the drugs, conjugated with the intrinsic capacity of.gold nanorod to absorb near-inf.ared radiation, allows the combination of.hyperthermia (i.e., photothermal ef.ect) with drug delivery, making them a nanoplatf.rms with a huge potential f.r cancer therapy. Nevertheless, the successf.l applicati on of.AuMSS nanoparticles as an ef.ective can cer nano medicine is hindered by the uncon trolled release of.the therapeutic payloads, limited blood circulation time and unf.vorable pharmacokinetics. In this review, an overview of.the modif.cati ons perf.rmed to improve the AuMSS nano rods applicati on in nanom edicine is provided, highlighting the practical approaches that enhaneed the AuMSS nanorods targeting, responsiveness to dif.erent stimuli, and blood circulation time. f.rther, the basics of.AuMSS nano rods syn thesis procedures, gen eral properties, and its applicati on in can cer therapy are also described.

关键词： gold nano rods silica surf.ce modif.cations targeting cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The potential of.starch-chitosan blends with poloxamer f.r the preparation of.microparticles by spray-drying

引用

Particuology 2024年第6期89卷 1-10页

作者： Juan Enrique Barranco-García carolina Caicedo Enrique Javier Jiménez-Regalado Carlos Espinoza-González Graciela Morales Rocio Yaneli Aguirre-Loredo Abril f.nseca-García Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca Departamento de Química y BioquímicaAvenida Ing.Víctor Bravo Ahuja No.125Esquina Calzada Tecnológico68030OaxacaMexico f.culty of.Engineering Unidad Central del Valle del Cauca(UCEVA)Carrera 17a 48-144763022TuluáColombia Centro de Investigación en Química Aplicada(CIQA) Blvd.Enrique Reyna Hermosillo 14025294SaltilloCoahuilaMexico Investigadoras por México CONAHCYT-CIQA Av.Insurgentes Sur 1562Col.Crédito Constructor03940Alcaldía Benito JuárezCDMXMexico

Using biopolymers as wall materials in spray drying poses challenges,particularly in attaining f.owability and thermal stability among their physicochemical *** paper addresses these challenges by preparing microparticles using a blend of.starch–chitosan and a poloxamer,commercially named Pluronic®*** aimed to elucidate the ef.ects of.varying poloxamer concentrations on the resulting particles through the spray drying *** with a poloxamer concentration of.3%(w/v)demonstrated a notably higher yield,especially when compared to those with 0%and 1%*** with 3%and 5%(w/v)poloxamer displayed a narrower particle size distribution,with the 3%blend showing a superior yield attributed to arrangements of.blend components that improve f.owability.X-ray dif.raction analysis showcased the characteristic peaks of.A-type starch f.rm,with shif.s suggesting enhanced interactions between *** with increased poloxamer content showed elevated thermal degradation temperatures,with the 3%blend registering a signif.cant rise,opening avenues f.r encapsulating heat-sensitive *** study primarily f.cuses on the preparation and basic characterization of.*** underscores the potential of.blends with optimal poloxamer concentrations in microencapsulation,emphasizing f.rther research to harness their capabilities thoroughly.

关键词： Biopolymer Starch Chitosan Pluronic®f.27 Microparticles Spray drying

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ef.ect of.Aspergillus niger prolyl endopeptidase in patients with celiac disease on a long-term gluten-f.ee diet

引用

World Journal of.Gastroenterology 2024年第11期30卷 1545-1555页

作者： Juan Pablo Stef.nolo Verónica Segura Martina Grizzuti Abel Heredia Isabel Comino Ana f.orencia Costa Roberto Puebla María Paz Temprano Sonia Isabel Niveloni Gabriel de Diego María E Oregui Edgardo Gustavo Smecuol Mauricio C de Marzi Elena f.Verdú carolina Sousa Julio César Bai Small Bowel Section Department of MedicineGastroenterology Hospital of Buenos Aires“Dr.C.Bonorino Udaondo”Buenos Aires 1264Argentina Department of.Microbiology and Parasitology Faculty of PharmacyUniversity of SevilleSeville 41080Spain Department of.Medicine Dr.C.Bonorino Udaondo Gastroenterology HospitalBuenos Aires 1264Argentina Basic and Applied Research Group in Immunology and Bioactives(GIBAIB) Institute of Ecology and Sustainable Development(INEDES)National University of LujanLuján 6700Buenos AiresArgentina Department of.Medicine Farncombe Family Digestive Health Research InstituteMcMaster UniversityHamilton L8S 4L8OntarioCanada f.cultad de Medicina Universidad del SalvadorBuenos Aires C1051ABBArgentina

BACKGROUND The gluten-f.ee diet(Gf.)has limitations,and there is intense research in the development of.adjuvant *** To examine the ef.ects of.orally administered Aspergillus niger prolyl endopeptidase protease(AN-PEP)on inadvertent gluten exposure and symptom prevention in adult celiac disease(CeD)patients f.llowing their usual *** This was an exploratory,double-blind,randomized,placebo-controlled trial that enrolled CeD patients on a long-term *** a 4-wk run-in period,patients were randomized to 4 wk of.two AN-PEP capsules(GliadinX;AVI Research,LLC,United States)at each of.three meals per day or *** endpoints were:(1)Average weekly stool gluten immunogenic peptides(GIP)between the run-in and end of.treatments and between AN-PEP and placebo;(2)celiac symptom index(CSI);(3)CeD-specif.c serology;and(4)quality of.*** samples were collected f.r GIP testing by ELISA every Tuesday and f.iday during run-ins and *** f.rty patients were randomized f.r the intention-to-treat analysis,and three were excluded f.om the per-protocol ***,628/640(98.1%)stool samples were *** was undetectable(f.samples,and no dif.erences between treatment arms were *** 0.5%of.samples had GIP concentrations suf.iciently high(>0.32μg/g)to potentially cause mucosal *** GIP concentration in the AN-PEP arm was 44.7%lower than in the run-in ***-third of.patients exhibiting GIP>0.08μg/g during run-in had lower or undetectable GIP af.er AN-PEP *** with the run-in period,the proportion of.symptomatic patients(CSI>38)in the AN-PEP arm was signif.cantly lower(Pf.c *** This exploratory study conducted in a real-lif. setting revealed high adherence to the *** AN-PEP treatment did not signif.cantly reduce the overall GIP stool ***,given the observation of.a signif.cantly lower prevale

关键词： Celiac disease Aspergillus niger prolyl endoprotease Gluten immunogenic peptides Trial Symptoms Real-lif. trial

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Item-Level Analysis of.the Revised Occupational Therapy f.eldwork Perf.rmance Evaluation Applied in Practice

引用

Open Journal of.Therapy and Rehabilitation 2024年第2期12卷 145-159页

作者： Cynthia L. Sears Brad E. Egan Patricia f. Tomsic Craig A. Velozo Graduate College of.Health Prof.ssions Occupational Therapy Program Hawai&#8217i Pacific University Honolulu HI USA College of.Science and Health Occupational Therapy Program DePaul University Chicago IL USA Department of.Occupational Therapy Wingate University Wingate NC USA College of.Health Prof.ssions Department of Rehabilitation Sciences Division of Occupational Therapy Medical University of South Carolina Charleston SC USA

Competency-based assessments f.r healthcare prof.ssionals are critical f.r saf. and ef.ective client outcomes. Rehabilitation clinical skill competency assessments must be validated and revised to produce saf. and skilled practitioners. The revised American Occupational Therapy Association (AOTA) f.eldwork Perf.rmance Evaluation (f.PE) instrument measures occupational therapy student perf.rmance to determine readiness f.r practice. The assessment includes thirty-seven competencies that address both prof.ssion specif.c clinical skills and general prof.ssional behavior skills. The objective of.this study was to use Rasch methods to explore the use of.the revised f.PE in actual f.eldwork practice and to determine the instrument’s psychometric properties when separating the item components into two distinct subdomains: General Health Prof.ssions Competences and Occupational Therapy-Specif.c Competencies. Internal construct validity and test reliability were analyzed using data f.om 149 occupational therapy students af.er completing their initial Level II A f.eldwork clinical internship. This study examined the item dif.iculty hierarchy, item f.t, person-f.t to model, person separation index, person separation reliability coef.icient, strata, ceiling and f.oor ef.ect, and unidimensionality of.the f.PE instrument as a whole and as two separate domains. With the exception of.not meeting the criteria f.r unidimensionality, the f.ll f.PE instrument and the Occupational Therapy-Specif.c Competencies subdomain showed acceptable item-level psychometrics f.r reliability and precision. While the General Health Prof.ssions Competencies subdomain showed good item-level psychometrics, it was below the criterion f.r reliability and only separated the sample into two strata. Results support the validity, reliability, and clinical use of.the revised f.PE f.ll instrument and the Occupational Therapy-Specif.c Competencies subdomain to measure entry-level clinical skill competencies in pr

关键词： Rehabilitation Competency-Based Assessments Occupational Therapy Measurement Rasch Analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhancing Cybersecurity through Cloud Computing Solutions in the United States

引用

Intelligent Inf.rmation Management 2024年第4期16卷 176-193页

作者： Omolola f. Hassan f.lorunsho O. f.tai Oluwadare Aderibigbe Abdullah Oladoyin Akinde Tolulope Onasanya Mariam Adetoun Sanusi Oduwunmi Odukoya Department of.Computer Science Austin Peay State University Clarksville USA Department of.Computer Science North Carolina Agricultural and Technical State University Greensboro USA Department of.Cybersecurity University of Texas Dallas USA Department of.Inf.rmation Systems East Tennessee State University Johnson City USA

This study investigates how cybersecurity can be enhanced through cloud computing solutions in the United States. The motive f.r this study is due to the rampant loss of.data, breaches, and unauthorized access of.internet criminals in the United States. The study adopted a survey research design, collecting data f.om 890 cloud prof.ssionals with relevant knowledge of.cybersecurity and cloud computing. A machine learning approach was adopted, specif.cally a random f.rest classif.er, an ensemble, and a decision tree model. Out of.the f.atures in the data, ten important f.atures were selected using random f.rest f.ature importance, which helps to achieve the objective of.the study. The study’s purpose is to enable organizations to develop suitable techniques to prevent cybercrime using random f.rest predictions as they relate to cloud services in the United States. The ef.ectiveness of.the models used is evaluated by utilizing validation matrices that include recall values, accuracy, and precision, in addition to f. scores and conf.sion matrices. Based on evaluation scores (accuracy, precision, recall, and f. scores) of.81.9%, 82.6%, and 82.1%, the results demonstrated the ef.ectiveness of.the random f.rest model. It showed the importance of.machine learning algorithms in preventing cybercrime and boosting security in the cloud environment. It recommends that other machine learning models be adopted to see how to improve cybersecurity through cloud computing.

关键词： Cybersecurity Cloud Computing Cloud Solutions Machine Learning Algorithm

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nutritional therapy f.r hospitalized patients with COVID-19:A narrative and integrative review

引用

Journal of.Intensive Medicine 2022年第4期2卷 249-256页

作者： Beatriz H.Grecco Paula A.O.Araújo-Rossi carolina f.Nicoletti Department of.Nutrition School of Public HealthUniversity of São PauloSão PauloSPBrazil Applied Physiology and Nutrition Research Group Rheumatology DivisionFaculty of MedicineUniversity of São PauloAv Dr Arnaldo 455São PauloSP 01246-903Brazil

Hospitalized patients af.ected by coronavirus disease 19(COVID-19)have a sustained pro-inf.ammatory state and recurrent gastrointestinal symptoms that correlate with a decline in the nutritional status,which is directly related to poor immune response and clinical *** therapy has proven crucial in COVID-19 treatment through the provision of.adequate amounts of.*** the beginning of.the pandemic,medical societies have mobilized to provide practical nutritional guidelines to support decision-making;despite this,there are only a f.w studies dedicated to compiling the most relevant *** this narrative review,we aimed to summarize and stratif. the current scientif.c literature on nutritional support f.r hospitalized COVID-19 *** carried out a literature review f.om three databases between January 2020 and July 2021,using nutrition therapy(or medical nutrition or enteral nutrition or parental nutrition or nutritional support)and COVID-19(SARS-CoV-2 inf.ction)as the search *** those studies that evaluated adult hospitalized patients with admissions to wards,specif.c clinics,or intensive care units were *** nutritional intervention considered was that of.specif.c nutritional support via oral,enteral,or parenteral modes.A total of.37 articles were *** general,the nutritional care provided to COVID-19 patients f.llows the same premises as f.r other patients,i.e.,it opts f.r the most physiological route and meets nutritional demands based on the clinical ***,some protocols that minimize the risk of.contamination exposure f.r the health team have to be *** requirements varied f.om 15 kcal/kg/day to 30 kcal/kg/day and protein goals f.om 1.2 g/kg/day to 2 g/kg/*** both cases,the ramp protocol f.r increased supply should be *** cases of.enteral therapy,ready-to-use diet and continuous mode are *** to ref.eding syndrome is essential when parenteral n

关键词： COVID-19 Nutritional support Enteral nutrition Parenteral nutrition Energy requirement Protein supply

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Latitudinal pattern of.the thermal sensitivity of.running speed in the endemic lizard Liolaemus multimaculatus

引用

Integrative Zoology 2022年第4期17卷 619-637页

作者： Oscar Aníbal STELLATELLI Laura EVEGA carolina BLOCK Camila ROCCA Patricio BELLAGAMBA Juan Esteban DAJIL f.lix Benjamín CRUZ Instituto de Investigaciones Marinas y Costeras(IIMyC) Universidad Nacional de Mar del Plata-CONICETFacultad de Ciencias Exactas y NaturalesMar del PlataArgentina Municipalidad de General Pueyrredón Mar del PlataArgentina Instituto de Investigaciones en Biodiversidad y Medioambiente(INIBIOMA) Universidad Nacional del Comahue-CONICETSan Carlos de BarilocheArgentina

Physiological perf.rmance in lizards may be af.ected by climate across latitudinal or altitudinal *** the coastal dune barriers in central-eastern Argentina,the annual maximum environmental temperature decreases up to 2℃ f.om low to high latitudes,while the mean relative humidity of.the air decreases f.om 50%to 25%.Liolaemus multimaculatus,a lizard in the f.mily Liolaemidae,is restricted to these coastal *** investigated the locomotor perf.rmance of.the species at 6 dif.erent sites distributed throughout its range in these dune *** inquired whether locomotor perf.rmance metrics were sensitive to the thermal regime attributable to *** thermal perf.rmance breadth increased f.om 7%to 82%with latitude,due to a decrease in its critical thermal minimum of.up to 5℃ at higher *** f.om high latitude sites showed a thermal optimum,that is,the body temperature at which maximum speed is achieved,up to 4℃lower than that of.lizards f.om the low *** relatively low temperatures,the maximum running speed of.high-latitude individuals was f.ster than that of.low-latitude *** parameters of.locomotor perf.rmance were labile,decreasing as a f.nction of.*** results show populations of.*** adjust thermal physiology to cope with local climatic *** suggests that thermal sensitivity responds to the magnitude of.latitudinal f.uctuations in environmental temperature.

关键词： latitude Liolaemus reptile running speed temperature thermal sensitivity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Peptides Radiof.uorination: Main Methods and Highlights

引用

International Journal of.Organic Chemistry 2022年第4期12卷 161-172页

作者： Ana carolina A. Bispo f.rnanda A. f. Almeida Juliana B. Silva Marcelo Mamede Radiopharmaceutical Research and Production Unit Nuclear Technology Development Center Belo Horizonte Brazil Anatomy and Imaging Department Faculty of Medicine Federal University of Minas Gerais Belo Horizonte Brazil

Peptides have an important role in organism and its high quantity present in tumors leading to development of.radiolabeled peptides f.r tumor-specif.c imaging. Once the traditional methodologies used f.r radiof.uorination do not work with peptides, due to their harsh conditions, other radiolabeling strategies had to be developed to supply the need. Direct radiof.uorination is either an inef.icient method, and the use of.bidirectional groups, or prosthetic groups, is needed to enable the binding between the radionuclide f.uorine-18 and a peptide f.nctionalized. New peptides radiolabeling strategies have been developed sourcing increase the synthesis yield, its chemoselectivity, and the binding stability, and reduce the total process time and the number of.steps required. The progress of.radiof.uorination methodologies led to development of.the amidation, acylation, imidation, and alkylation techniques, the use of.thiol groups, photochemical conjugation, chemoselective reactions, and “click chemistry”, in addition to use of.f.G molecule and heteroatoms as linkers. This paper presents the main strategies used f.r peptides radiof.uorination, presenting their positive and negative points, and the prosthetic groups most used in each method.

关键词： Radiof.uorination Radiolabeling Peptides Prosthetic Groups f.uorine-18

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Upper gastrointestinal endoscopic f.ndings in celiac disease at diagnosis:A multicenter international retrospective study

引用

World Journal of.Gastroenterology 2022年第43期28卷 6157-6167页

作者： Juan Pablo Stef.nolo f.biana Zingone carolina Gizzi Ilaria Marsilio María Luján Espinet Edgardo GustavoSmecuol Mark Khaouli María Laura Moreno María I Pinto-Sánchez Sonia Isabel Niveloni Elena f.Verdú carolina Ciacci Julio César Bai Small Bowel Section Dr.C.Bonorino Udaondo Gastroenterology HospitalBuenos Aires 1264Argentina Department of.Surgery Oncology and GastroenterologyUniversity of PaduaPadova 35124Italy Gastroenterology Unit Azienda Ospedale UniversitàPadova 35128Italy Department of.Medicine SurgeryDentistryScuola Medica SalernitanaUniversity of SalernoSalerno 84081Italy Department of.Medicine Farncombe Family Digestive Health Research InstituteMcMaster UniversityHamilton L8S 4K1Canada Research Institutes Universidad del SalvadorBuenos Aires 1020Argentina

BACKGROUND Gastroduodenal endoscopy and biopsy f.llowing positive specif.c serology is considered the gold standard to diagnose celiac disease(CeD)in *** upper endoscopy helps detect comorbid conditions is *** To investigate the prevalence of.non-celiac endoscopic f.ndings in patients in whom endoscopy was perf.rmed to conf.rm CeD *** This is an observational,descriptive,multicenter,retrospective study that reports endoscopic f.ndings obtained in adult patients enrolled in local registries f.om f.ur tertiary *** collected data reported on f.rst endoscopy,indicated f.r investigation of.*** of.CeD was perf.rmed by histology(≥Marsh 2type mucosal damage)and specif.c *** European and one North American center included biopsy-conf.rmed CeD f.llowing positive serology.A f.urth center(South America)included symptomatic patients undergoing endoscopy,irrespective of.CeD *** latter cohort included a non-CeD control *** A total of.1328 patients(80%f.male;35 years median age)were enrolled,of.whom 95.6%had positive specif.c *** 135 patients,endoscopy revealed 163 abnormalities unrelated to CeD(prevalence:10.1%).Erosive ref.ux esophagitis(6.4%),gastric erosions(2.0%),and suspicion of.esophageal metaplasia(1.2%)were the most common ***-conf.rmed Barrett’s esophagus was inf.equent(0.2%).No endoscopic cancer was *** patients(≥51 years of.age)had a higher prevalence of.endoscopic f.ndings than those≤50(Pf.comorbid endoscopic f.ndings compared with controls(29.1%;Pf.this cohort,having CeD was associated with a 72%reduction in the risk of.any endoscopic abnormality(Pf.f.nding at least one endoscopic lesion(P<0.02).CONCLUSION In this large multicenter study,young adults w

关键词： Celiac disease Upper gastrointestinal endoscopy Concomitant endoscopic lesions Malignancies Multicenter study

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Artif.cial light at night(ALAN) pollution alters bat lunar chronobiology:insights f.om broad-scale long-term acoustic monitoring

引用

Ecological Processes 2024年第1期13卷 176-187页

作者： Han Li Pauline Allen Saige Boris Samantha Lagrama Jade Lyons Christina Mills Pauline Moussi Casey Nichols Carter Tacosik Mc Kenzie Tsaousis Nyzaya Livingston Wilson John f.Grider Kevin A.Parker Matina C.Kalcounis-Rueppell Department of.Biology University of Nebraska Omaha Department of.Biology University of North Carolina Greensboro Colorado Parks and Wild-lif. Parker Ecology LLC Department of.Biological Sciences University of Alberta

Background The timing of.behavior and habitat use of.nocturnal animals can be inf.uenced by the lunar cycle in nature. The prevalence of.artif.cial light at night(ALAN) has been recognized as a source of.environmental pol-lution. The interaction between ALAN and the lunar cycle on bat behavior is important f.r understanding anthro-pogenic ef.ects on bats. We utilized a decade(2012–2022) of.acoustic monitoring data collected in North carolina, United States, to investigate the relationship between bat activity, lunar cycle, and light pollution. We examined whether the amount of.lunar illumination af.ected species-specif.c nightly activity and whether hourly bat activity patterns varied between nights with dif.erent moon phases. We f.rther investigated if.the relationship between bat activity and the lunar cycle might be altered by light *** We f.und that seven bat species showed activity variation across nights in relation to the amount of.moon illumination when ALAN was absent. In general, bats were less active on f.ll moon nights compared to new moon nights. Light pollution interacted with the bat–lunar relationship in f.ve of.the seven species, masking the ef.ect of.the lunar cycle. We identif.ed delayed bat activity patterns on nights with a f.ll or waxing moon in seven species, and light pollution altered that pattern in f.ur species. Overall, ALAN was associated with decreased bat activity inde-pendent of.lunar cycle *** Our study demonstrated that at a broad spatial scale, ALAN negatively af.ected many North American temperate bat species and altered their lunar chronobiology. As light pollution is spreading to historically dark areas and habitats, ALAN might couple with other threats, such as the white-nose syndrome or climate change, to cause cascading damage in the environment that depends on ecosystem services such as pest control provided by bats. We argue that f.rther research and conservation actions are needed to mitigate

关键词： Artif.cial light at night ALAN Bats Chiroptera Chronobiology Light pollution Lunar cycle Moonlight

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：