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Experimental evidence for heritable reproductive time in 2 allochronic populations of pine processionary moth

Insect Science 2017年第2期24卷 325-335页

作者： Manuela Branco Maria-Rosa Paiva Helena Maria Santos Christian Burban carole Kerdelhue Centro de Estudos Florestais (CEF) Instituto Superior de Agronomia (ISA) Universidade de Lisboa (ULisboa) 1349-017 Lisboa Portugal CENSE Faculty of Sciences and Technology (FCT) Universidade Nova de Lisboa (UNL) 2829-516 Caparica Portugal INRA Centre de Bordeaux UMR1202 BIOGECO Cestas cedex France INRA Centre de Montpellier UMR CBGP F-34988 Montferrier-sur-Lez cedex France

Phenology allows organisms to overcome seasonally variable conditions through life-cycle adjustment. Changes in phenology can drastically modify the evolutionary tra- jectory of a population, while a shift in the reproductive time may cause allochronic differentiation. The hypothesis of heritable reproductive time was experimentally tested, by studying a unique population of the pine processionary moth Thaumetopoeapityocampa （Den. ＆ Schiff.） which has a shifted phenology, and however co-occurs with the typical population following the classical life cycle. When populations of both types were reared under controlled conditions, the reproductive time was maintained asynchronous, as ob- served in the field. The shifted population was manipulated in the laboratory to reproduce later than usual, yet the offspring emerged in the next year at the expected dates thus ＂com- ing back＂ to the usual cycle. Hybrids from crosses performed between the 2 populations showed an intermediate phenology. From the emergence times of parents and offspring, a high heritability of the reproductive time （h = 0.76） was observed. The offspring ob- tained from each type of cross was genetically characterized using microsatellite markers. Bayesian clustering analysis confirmed that hybrids can he successfully identified and separated from the parental genetic classes by genotyping. Findings support the hypothesis that, for this particular population, incipient allochronic speciation is due to a heritable shift in the reproductive time that further causes assortative mating and might eventually cause ecological adaptation/maladaptation in response to environmental changes.

关键词： allochronic speciation experimental crossings heritability phenology reproductive isolation Thaumetopoeapityocampa

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Exploring the Current Practices,Costs and Benefits of FAIR Implementation in Pharmaceutical Research and Development:A Qualitative Interview Study

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Data Intelligence 2021年第4期3卷 507-527页

作者： Ebtisam Alharbi Rigina Skeva Nick Juty Caroline Jay carole Goble School of Computer Science University of ManchesterManchesterManchester M139PLUK College of Computer and Information Systems Umm Al-Qura UniversityMeccaMakkah 21421Saudi Arabia

The findable,accessible,interoperable,reusable(FAIR)principles for scientific data management and stewardship aim to facilitate data reuse at scale by both humans and *** and development(R&D)in the pharmaceutical industry is becoming increasingly data driven,but managing its data assets according to FAIR principles remains costly and *** date,little scientific evidence exists about how FAIR is currently implemented in practice,what its associated costs and benefits are,and how decisions are made about the retrospective FAIRification of data sets in pharmaceutical R&*** paper reports the results of semi-structured interviews with 14 pharmaceutical professionals who participate in various stages of drug R&D in seven pharmaceutical *** thematic analysis identified three primary themes of the benefits and costs of FAIRification,and the elements that influence the decision-making process for FAIRifying legacy data *** collectively acknowledged the potential contribution of FAIRification to data reusability in diverse research domains and the subsequent potential for *** costs,however,were still considered a barrier by participants,with the need for considerable expenditure in terms of resources,and cultural *** decisions were made about FAIRification was influenced by legal and ethical considerations,management commitment,and data *** findings have significant implications for those in the pharmaceutical R&D industry who are engaged in driving FAIR implementation,and for external parties who seek to better understand existing practices and challenges.

关键词： FAIR FAIRification Retrospective FAIRification Pharmaceutical R&D Cost-benefit Decision-making process

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Ellagic acid in strawberry(Fragaria spp.):Biological,technological,stability,and human health aspects

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Food Quality and Safety 2017年第4期1卷 227-252页

作者： Selva Muthukumaran carole Tranchant John Shi Xingqian Ye Sophia Jun Xue Department of Food Science and Post-Harvest Technology Institute of TechnologyHaramaya UniversityPost Box 138Dire DawaEthiopia School of Food Science Nutrition and Family StudiesFaculty of Health Sciences and Community ServicesUniversitéde MonctonMonctonNew Brunswick E1A 3E9Canada***Guelph Research and Development CenterAgriculture and Agri-Food Canada93 Stone Road WestGuelphOntario N1G 5C9Canada School of Biosystems Engineering and Food Science Zhejiang UniversityHangzhouChina

Ellagic acid(EA)is one of the plant phenolics associated with human health *** derives from ellagitannins found in some nuts,seeds,and fruits,especially *** are considered a functional food and nutraceutical source,mainly because of their high concentration of EA and its *** review presents the current state of knowledge regarding EA,focusing on its content in strawberry plants,stability during processing and storage of strawberry-based foods,production methods,and relevance to human *** alternatives to acid-solvent extraction,fermentation-enzymatic bioprocesses hold great promises for more eco-efficient production of EA from plant *** fruits are generally rich in EA,with large variations depending on cultivar,growth conditions and maturity at *** EA contents are also reported in strawberry achenes and leaves,and in wild *** postharvest storage,processing and subsequent storage can influence EA *** low concentration in strawberry juice and wine can be increased by incorporating pre-treated *** recognition of strawberries as functional foods is substantiated by evidence of EA biological effects,including antioxidant,antiinflammatory,antidiabetic,cardioprotective,neuroprotective,and prebiotic *** health benefits attributed to EA-rich foods are thought to involve various protective mechanisms at the cellular *** EA is converted by the intestinal microbiota to urolithins,which are better absorbed than EA and may contribute significantly to the health effects attributed to EA-rich *** on the evidence available,strawberry EA shows strong promises for functional,nutraceutical,and pharmaceutical *** research should be directed at quantifying EA in different parts of the strawberry plant and in their byproducts;optimizing EA production from byproducts;understanding the biological actions of EA-derived metabolites in vivo,inc

关键词： Strawberry plant Ellagic acid Processing Metabolism Bioacti

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Wives of the American presidents

Wives of the American presidents

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作者： carole Chandler Waldrup.

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Seed provenance determines germination responses of Rumex crispus (L.) under water stress and nutrient availability

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Journal of Plant Ecology 2019年第6期12卷 949-961页

作者： María Pérez-Fernández carole PElliott Alex Valentine JoséAntonio Oyola Ecology Area University Pablo de OlavideCarretera de Utrera Km 141013 SevillaSpain Kings Park Science Botanic Garden and Parks AuthorityDepartment of BiodiversityConservation and AttractionsKattidj CloseKings ParkWA 6005Australia School of Biological Science The University of Western AustraliaCrawleyWA 6009Australia Department of Botany and Zoology Stellenbosch UniversityPrivate Bag X1Matieland 7602South Africa Physics Department University of ExtremaduraAvenida de Elvas s/n06006 BadajozSpain

Aims Seeds of Rumex crispus from six provenances were studied in relation to their germination under drought and presence of nitrogen in the germination and emergence *** also investigated whether adaptation to soil increases the ability of the species to colonize and establish in contrasting environments along a longitudinal gradient in western Spain by means of a reciprocal transplantation *** We conducted a germination trial in the lab to test for the germination responses to water scarcity along a polyethylene glycol gradient and to varying concentrations of nitrogen *** reciprocal transplantations experiment was conducted,where seeds from six provenances were grown in the soils from the very same *** emergence,survivorship and fitness-related variables were measured in all *** Findings We found that *** has a cold-stratification requirement that enhances its *** differences between the six provenances were detected for time-to-germination,total seedling emergence,plant mortality and reproductive effort in all the *** differences between provenances with respect to germination were confirmed by the significant statistical analyses of the variance,thus providing evidence that seeds from parent plants grown in different environmental conditions have an intrinsically different abilities to germinate and *** nitrogen content where seed germination and seedlings establish also play an important role in their performance in terms of survivorship and reproduction,being the higher levels of inorganic nitrogen and of microbial biomass those that increased biomass production,enhanced inflorescence formation and reduced plant *** conclude that one of the main reasons for the spread and maintenance of *** would be the increased levels of nitrogen in agricultural soils.

关键词： seed provenance germination latitudinal gradient drought N-compounds soil properties

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Origin of the neuro-sensory system: new and expected insights from sponges

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Integrative Zoology 2009年第3期4卷 294-308页

作者： EMMANUELLE RENARD Jean VACELET Eve GAZAVE Pascal LAPéBIE carole BORCHIELLINI Alexander V.ERESKOVSKY Centre d’océanologie de Marseille CNRS–Aix-Marseille UniversitéMarseilleFrance Department of Embryology Saint-Petersburg State UniversitySt.PetersburgRussia

The capacity of all cells to respond to stimuli implies the conduction of information at least over short *** multicellular organisms,more complex systems of integration and coordination of activities are *** most animals,the processing of information is performed by a nervous *** the most basal taxa,sponges are nerveless so that it is traditionally assumed that the integrated neuro-sensory system originated only once in Eumetazoa,a hypothesis not in agreement with some recent phylogenomic *** aim of this review is to show that recent data on sponges might provide clues for understanding the origin of this complex ***,sponges are able to react to external stimuli,and some of them display spontaneous movement *** coordinated behaviors involve nervous system-like mechanisms,such as action potentials and/or ***,genomic analyses show that sponges possess genes orthologous to those involved in the patterning or function-ing of the neuro-sensory system in ***,some of these genes are expressed in specific cells(flask cells,choanocytes).Together with ultrastructural data,this gives rise to challenging hypotheses concerning cell types that might play neuro-sensory-like roles in sponges.

关键词： animal evolution choanocyte flask cells nervous system Porifera signal transduction.

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An integrative review of the influence of job strain and coping on nurses'work performance:Understanding the gaps in oncology nursing research

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International Journal of Nursing Sciences 2017年第4期4卷 418-429页

作者： Dhuha Youssef Wazqar Mickey Kerr Sandra Regan carole Orchard Faculty of Nursing King Abdulaziz UniversityAl-Sharafeyah StreetP.Box:42828Jeddah21551Saudi Arabia Arthur Labatt Family School of Nursing University of Western Ontario1151 Richmond Street LondonOntarioN6A3K7Canada

Nursing is known to be a stressful profession that can lead to physical and psychological health issues and behavioural *** oncology,workload among nurses is believed to be increasing in conjunction with rapidly increasing numbers of patients with cancer and staff shortages worldwide,therefore it is essential to sustain a quality oncology nurse *** studies have presented evidence on job strain,effects of coping strategies,and nurses'work performance within healthcare settings,but few have focused on oncology settings and none of these on nurses working in Saudi *** purpose of this review was to summarize empirical and theoretical evidence concerning job-related stressors in nurses,particularly oncology nurses,and the interrelationships among job strain,coping strategies,and work performance in this *** strategies identified studies published on studies in peer-reviewed journals from 2004 to ***-five nursing studies were found examining the relationships among the concepts of *** job-related stressors among oncology nurses were high job demands,dealing with death/dying,lack of job control,and interpersonal conflicts at *** strain was found to be significantly linked to coping strategies,and negatively associated with work performance among nurses in *** is no existing empirical evidence to support the relationship between coping strategies and work performance among oncology *** present evidence is limited,and a considerable amount of research is required in the future to expand the oncology nursing *** is needed to investigate job-related stressors and their effects on oncology nurses.

关键词： Coping Job strain Nurses Review Work performance

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Cell-specific pathways recruited for symbiotic nodulation in the Medicago truncatula legume

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Molecular Plant 2022年第12期15卷 1868-1888页

作者： Sergio Alan Cervantes-Pérez Sandra Thibivilliers carole Laffont Andrew D.Farmer Florian Frugier Marc Libault Department of Agronomy and Horticulture Center for Plant Science InnovationUniversity of Nebraska-LincolnLincolnNE 68503USA Single Cell Genomics Core Facility Center for BiotechnologyUniversity of Nebraska-LincolnLincolnNE 68588USA Institute of Plant Sciences Paris-Saclay(IPS2) UniversitéParis-SaclayCNRSINRAEUniversitéParis-CitéUniversitéd’Evry91190 Gif-sur-YvetteFrance National Center for Genome Resources Santa FeNM 87505USA

Medicago truncatula is a model legume species that has been studied for decades to understand the symbiotic relationship between legumes and soil bacteria collectively named *** symbiosis called nodulation is initiated in roots with the infection of root hair cells by the bacteria,as well as the initiation of nodule primordia from root cortical,endodermal,and pericycle cells,leading to the development of a new root organ,the nodule,where bacteria fix and assimilate the atmospheric dinitrogen for the benefit of the ***,we report the isolation and use of the nuclei from mock and rhizobia-inoculated roots for the single nuclei RNA-seq(sNucRNA-seq)profiling to gain a deeper understanding of early responses to rhizobial infection in Medicago roots.A gene expression map of the Medicago root was generated,comprising 25 clusters,which were annotated as specific cell types using 119 Medicago marker genes and orthologs to Arabidopsis cell-type marker genes.A focus on root hair,cortex,endodermis,and pericycle cell types,showing the strongest differential regulation in response to a short-term(48 h)rhizobium inoculation,revealed not only known genes and functional pathways,validating the sNucRNA-seq approach,but also numerous novel genes and pathways,allowing a comprehensive analysis of early root symbiotic responses at a cell type-specific level.

关键词： Medicago root single-cell transcriptomic rhizobium nodule initiation root hair cells cortical cells

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Golden hour for perovskite photonics

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Photonics Research 2020年第12期8卷 I0001-I0004页

作者： QING ZHANG carole DIEDERICHS QIHUA XIONG Department of Materials Science and Engineering College of EngineeringPeking UniversityBeijing 100871China Laboratoire de Physique de l’Ecole Normale Supérieure ENSUniversitéPSLCNRSSorbonne UniversitéUniversitéde ParisF-75005 ParisFrance Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological UniversitySingapore 637371Singapore

Halide perovskite semiconductors have emerged as promising candidates for the next-generation low-energy consumption,high-flexibility photonics and optoelectronic devices thanks to their superior optical and excitonic properties as well as fabrication *** special issue,including three review papers and six original research papers,focuses on the studies of both fundamentals and applications of perovskite photonics,covering materials,excitonic properties,nonlinear optics,strong light–matter interactions,and optoelectronic devices.

关键词： optoelectronic Golden perovskite

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Crossing Borders and Boundaries:Ways of Reading Some Contemporary Asian Australian Women’s Fictions

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Comparative Literature:East & West 2014年第1期19卷 1-17页

作者： carole FERRIER School of English Media Studies and Art HistoryThe University of Queensland

20世纪末以来,亚裔妇女作家在澳大利亚兴起成为一个独具特色的创作群体。她们的创作往往被视为一股多元文化力量,既是对传统"白澳"观念的挑战,同时也推动了多元、异质的澳大利亚文化认同的形成。作者在此文中围绕亚裔妇女文学及其新近... 详细信息

20世纪末以来,亚裔妇女作家在澳大利亚兴起成为一个独具特色的创作群体。她们的创作往往被视为一股多元文化力量,既是对传统"白澳"观念的挑战,同时也推动了多元、异质的澳大利亚文化认同的形成。作者在此文中围绕亚裔妇女文学及其新近批评情况,采用动态的历史批评观,反思了在澳大利亚研究、亚裔澳大利亚研究、多元文化主义、身份研究等研究领域內对亚裔妇女文学创作僵化和单一的解读模式。作者认为,在全球化条件下,作为离散文学,澳大利亚亚裔妇女文学创作事实上要复杂得多,它们与澳大利亚主流权力和话语之间既对抗又迎合,并且还受到以唐恩美为首的美国亚裔文学先例的影响。

关键词： Australian 妇女文学文学创作创作群体批评观多元文化唐恩 Reading fict

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