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Journal of Ancient Civilizations 2000年 97-104页

作者： Lucy GOODISON,Christine morris,carol Hershenson

PDGFRαreporter activity identifies periosteal progenitor cells critical for bone formation and fracture repair

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Bone Research 2022年第1期10卷 122-136页

作者： Jiajia Xu Yiyun Wang Zhu Li Ye Tian Zhao Li Amy Lu Ching-Yun Hsu Stefano Negri Cammy Tang Robert J.Tower carol morris Aaron W.James Departments of Pathology Johns Hopkins UniversityBaltimoreMD 21205USA Departments of Orthopedics Johns Hopkins UniversityBaltimoreMD 21205USA Department of Oral and Maxillofacial Surgery School of StomatologyChina Medical UniversityShenyangLiaoningPR China

The outer coverings of the skeleton,which is also known as the periosteum,are arranged in concentric layers and act as a reservoir for tissue-specific bone *** cellular heterogeneity within this tissue depot is being increasingly ***,inducible PDGFRαreporter animals were found to mark a population of cells within the periosteum that act as a stem cell reservoir for periosteal appositional bone formation and fracture *** these processes,PDGFRαreporter^(+)progenitors give rise to Nestin+periosteal cells before becoming osteoblasts and *** diphtheria toxin-mediated ablation of PDGFRαreporter^(+)cells led to deficits in cortical bone formation during homeostasis and a diminutive hard callus during fracture *** ossicle transplantation,both mouse PDGFRαreporter^(+)periosteal cells and human Pdgfrα+periosteal progenitors expand,ossify,and recruit marrow to a greater extent than their counterpart periosteal cells,whereas PDGFRαreporter^(−)periosteal cells exhibit a predisposition to chondrogenesis in *** RNA sequencing identified enrichment of the secreted factors Fermt3 and Ptpn6 within PDGFRαreporter^(+)periosteal cells,which partly underlie the osteoblastogenic features of this cell population.

关键词： progenitor fracture reservoir

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Comparison of skeletal and soft tissue pericytes identifies CXCR4+ bone forming mural cells in human tissues

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Bone Research 2020年第3期8卷 286-299页

作者： Jiajia Xu Dongqing Li Ching-Yun Hsu Ye Tian Leititia Zhang Yiyun Wang Robert J.Tower Leslie Chang carolyn A.Meyers Yongxing Gao Kristen Broderick carol morris Jody E.Hooper Sridhar Nimmagadda Bruno Peault Aaron W.James Departments of Pathology Johns Hopkins UniversityBaltimore 21205 MDUSA Department of Microbiology Wuhan University School of Basic Medical of ScienceWuhanHubeiP.R.China Department of Oral and Maxillofacial Surgery School of StomatologyChina Medical UniversityShenyangLiaoningP.R.China Departments of Orthopaedics Johns Hopkins UniversityBaltimore 21205 MDUSA Departments of Plastic Surgery Johns Hopkins UniversityBaltimore 21205 MDUSA Departments of Autopsy Service Johns Hopkins UniversityBaltimoreMD 21205USA Departments of Radiology and Radiological Science bonBaltimore 21205 MDUSA UCLA and Orthopaedic Hospital Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center Los AngelesCA 90095USA Center for Cardiovascular Science and MRC Center for Regenerative Medicine University of EdinburghEdinburghUK

Human osteogenic progenitors are not precisely defined,being primarily studied as heterogeneous multipotent cell populations and termed mesenchymal stem cells(MSCs).Notably,select human pericytes can develop into bone-forming ***,we sought to define the differentiation potential of CD146 f human pericytes from skeletal and soft tissue sources,with the underlying goal of defining cell surface markers that typify an osteoblastogenic ***146+CD31~CD45_pericytes were derived by fluorescence-activated cell sorting from human periosteum,adipose,or dermal *** CD146+CD31—CD45 cells retained canonical features of pericytes/*** pericytes demonstrated a striking tendency to undergo osteoblastogenesis in vitro and skeletogenesis in vivo,while soft tissue pericytes did not *** analysis revealed higher CXCR4 signaling among periosteal pericytes in comparison to their soft tissue counterparts,and CXCR4 chemical inhibition abrogated ectopic ossification by periosteal ***,enrichment of CXCR4+pericytes or stromal cells identified an osteoblastic/non-adipocytic precursor *** sum,human skeletal and soft tissue pericytes differ in their basal abilities to form *** exists in soft tissue pericytes,however,and CXCR4+pericytes represent an osteoblastogenic,non-adipocytic cell ***,enrichment for CXCR4-expressing stromal cells is a potential new tactic for skeletal tissue engineering.

关键词： CD146 CXCR4 pericyte

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网络信息化联盟（CNI）2012年秋季成员会议：未来的学术研究

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图书情报工作动态 2013年第4期 4-7页

作者： carol Minton morris() 张丽华(编译) 魏蕊(校对)

网络信息化联盟（CNI）的秋季成员会议于2012年12月10—11日在弗吉尼亚州的阿林顿举行，本次会议包括了探索如何管理、维护、共享、识别、保存、利用并构建各种类型数字内容（重点是研究数据）的全球社区的内容展示。一、概述“数字图... 详细信息

网络信息化联盟（CNI）的秋季成员会议于2012年12月10—11日在弗吉尼亚州的阿林顿举行，本次会议包括了探索如何管理、维护、共享、识别、保存、利用并构建各种类型数字内容（重点是研究数据）的全球社区的内容展示。一、概述“数字图书馆”这一术语在上世纪九十年代成为常用词汇。当时知识产权问题集中在在线访问元数据和文档上。而在2013年，人们希望能够将内容控制的力度细化到个体数据集和单一图像的水平，并有能力提供对于大规模研究数据和各种类型数字内容的开放获取和长期保存。

关键词：网络信息化学术研究成员秋季联盟数字内容知识产权问题长期保存

Ancient *** Myths and Evidence

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Journal of Ancient Civilizations 2000年第1期15卷 97-104页

作者： Lucy GOODISON Christine morris carol Hershenson

Effect of acupressure on postpartum low back pain, salivary cortisol, physical limitations, and depression: a randomized controlled pilot study

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Journal of Traditional Chinese Medicine 2020年第1期40卷 128-136页

作者： Cheng Hsuesh-Yu carol Shieh Wu Bei-Yu Cheng Yu-Fen Department of Nursing Kaohsiung Chang Gung Memorial HospitalKaohsiung 80830Taiwan China Department of Community and Health Systems Indiana University School of NursingIndiana 600USA Department of Chinese Medicine Kaohsiung Chang Gung Memorial HospitalKaohsiung 80830Taiwan China

OBJECTIVE:To investigate the effect of acupressure on postpartum low back pain(LBP),salivary cortisol,physical limitations,and postpartum ***:Participants were 70 postpartum women who were randomly assigned to either an intervention(n=35)or a control(n=35)*** intervention group received 10 acupressure sessions(1 session per day,5 d per week).The control group received 10 sham acupressure *** were assessed using a visual analogue scale(LBP intensity),salivary cortisol values(LBP biomarker),and Chinese versions of the Roland-morris Disability Questionnaire(daily activity limitations),Oswes-try Disability Index(physical activity limitations),and the Edinburgh Postnatal Depression Scale(postpartum depression).RESULTS:Participants in the intervention group had significantly lower levels of LBP intensity,daily activity limitations,physical activity limitations,and postpartum depression than those in the control *** was no significant between-group difference in salivary ***:Acupressure may reduce postpartum LBP intensity and limitations in daily and physical activity,and alleviate postpartum depressive *** should be offered in postpartum care settings as an alternative treatment for postpartum women with LBP.

关键词： Acupressure Low back pain Postpartum period Depression Randomized controlled trial Pilot projects

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日益增长的Google图书：保存访问及长尾问题

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图书情报工作动态 2010年第12期 23-24页

作者： carol Minton morris 肖潇（编译）许德山（校对）

谷歌图书计划（GBP）被不同的人群认为具有以下特征：违反美国及世界其他地方的著作权法；促进全球出版行业的发展；标志着开放知识运动开始起步；属于一种信息垄断；是全球人类科学文化记录数字化保存及获取的关键组成部分。

关键词： Google 保存图书长尾著作权法出版行业信息垄断文化记录