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DRAC:A computer software for the analysis of rock mechanics problems

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DRAC:A computer software for the analysis of rock mechanics ...

Targeting the BDNF/TrkB Pathway in Poor Prognosis Neuroblastoma

International Symposium on Application of Computer methods in Rock mechnics and Engineering

作者： P.C.Prat A.Gens I.carol A.Ledesma j.A.Gili Dept.of Geotechnical Engrg. Technical University of CatalunyaBarcelonaSPAIN

＜正＞The paper describes the computer software DRAC,a powerful code specifically developed to perform finite element analysis of Rock mechanics engineering problems in two and three dimensions. The package includes several types of finite elements in two and three dimensions,j.int elements to model rock discontinuities,linear elements to represent rock bolts,facilities to simulate excavation and construction,a new procedure to introduce an equilibrium initial stress state,advanced numerical features for non-linear analysis and a great variety of constitutive models for the continuum,j.int and linear *** same computer package includes a post-processor specially designed to handle output of the main program in two and three *** performance of the software is illustrated by its application to the analysis of the excavation of a large cavern in rock.

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Targeting the BDNF/TrkB Pathway in Poor Prognosis Neuroblast...

中国抗癌协会第七届全国小儿肿瘤学术会议

作者： carol j.Thiele j.rry j.boin Hideya Onish Amy mcKee j.nnifer j.ckson Kelly martin Cell & molecular Biology Section Pediatric Oncology BranchCenter for Cancer ResearchNational Cancer InstituteNational Institutes of HealthBethesda HematologY Lab Second Affiliated HospitalChina Medical UniversityShenyangChina

Patients with Neuroblastoma (NB) whose tumors express high levels of Brain Derived Neurotrophic Factor (BDNF) and its tyrosine kinase receptor,TrkB,have a poor ***,tumors derived from these patients are chemoresistant,highly angiogenic and *** normal development BDNF stimulates cell survival, differentiation and function in normal neural cells via selective activation of the TrkB

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莫迪格利阿尼

丛书名：国外现代画家译丛

1989年

作者：卡罗·曼 carol mann 陈乃望译

来源：汇雅图书（南通市图书馆... 评论

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创建新血系:一只种公羊的妙用

今日畜牧兽医 2009年第4期25卷 60-62页

作者： carol j.Elkins 于海良河北省丰宁满族自治县农牧局

许多拥有小规模羊群的业主每2-3年内替换一次种公羊．以避免造成近亲繁殖。可他们发现，寻找替代的公羊远比想象的要难的多。如果他们饲养的羊只具有很好的群体质量，他们可能很难找到与其同等或优于原羊群的不是近血系的公羊进行替代... 详细信息

许多拥有小规模羊群的业主每2-3年内替换一次种公羊．以避免造成近亲繁殖。可他们发现，寻找替代的公羊远比想象的要难的多。如果他们饲养的羊只具有很好的群体质量，他们可能很难找到与其同等或优于原羊群的不是近血系的公羊进行替代。索性找到一个新的“好”公羊，却发现与母羊很不“般配”：它们的遗传组合也不是原来想要的性状．

关键词：种公羊近亲繁殖群体质量小规模羊群遗传母羊

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嘉理思生平及著作目录

嘉理思生平及著作目录

Histone H3.3G34-mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis

1984年

作者：弗伦克 j.拉多夫斯基（Frank j.Radovsky）卡罗尔 N.海加（carol N.Higa）华立中译

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四川生理科学杂志 2020年第4期42卷 480-480页

作者： carol C L Chen Department of Human Genetics McGill University Montreal QC H3A 0C7 Canada Division of Experimental medicine Department of Medicine McGill University Montreal QC H4A 3J1 Canada Quantitative Life Sciences McGill University Montreal QC H3A 2A7 Canada Lady Davis Research Institute Jewish General Hospital Montreal QC H3T 1E2 Canada Department of Pediatrics McGill University and The Research Institute of the McGill University Health Centre Montreal QC H4A 3J1 Canada Canadian Centre for Computational Genomics McGill University Montreal QC H3A 0E9 Canada Developmental and Stem Cell Biology Program The Hospital for Sick Children Toronto ON M5G 0A4 Canada The Arthur and Sonia Labatt Brain Tumour Research Centre The Hospital for Sick Children Toronto ON M5G 0A4 Canada Department of Oncology and The milner Institute Jeffrey Cheah Biomedical Centre University of Cambridge Cambridge CB2 0AW UK CRUK Children’s Brain Tumour Centre of Excellence University of Cambridge Cambridge CB2 0RE UK Nuclear Function in CNS Pathophysiology German Center for Neurodegenerative Diseases (DZNE) Bonn 53127 Germany Dana-Farber/Boston Children’s Cancer and Blood Disorders Center Boston MA 02215 USA Department of Pathology Montreal Neurological Institute McGill University Montreal QC H3A 2B4 Canada Department of Pathology Montreal Children’s Hospital McGill University Health Centre Montreal QC H4A 3J1 Canada UCL Queen Square Institute of Neurology London WC1N 3BG UK Department of Biochemistry and Biophysics and Penn Epigenetics Institute Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104-6073 USA Department of Biochemistry McGill University Montreal QC H3A 1A3 Canada Second Department of Paediatrics Semmelweis University Budapest 1094 Hungary Department of Neurosurgery University of Debrecen Debrecen 4032 Hungary Department of Oncology Faculty of Medicine University of Debrecen Debrecen 4032 Hungary Department of Paediatric Haematology and Oncol

Histone H3.3 glycine 34 to arginine/valine(G34R/V)mutations drive deadly gliomas and show exquisite regional and temporal specificity,suggesting a developmental context permissive to their *** we show that 50%of G34R/V tumors(n=95)bear activating PDGFRA mutations that display strong selection pressure at *** considered gliomas,G34R/V tumors actually arise in GSX2/DLX-expressing interneuron progenitors,where G34R/V mutations impair neuronal *** lineage of origin may facilitate PDGFRA co-option through a chromatin loop connecting PDGFRA to GSX2 regulatory elements,promoting PDGFRA overexpression and *** the single-cell level,G34R/V tumors harbor dual neuronal/astroglial identity and lack oligodendroglial programs,actively repressed by GSX2/DLX-mediated cell fate specification.G34R/V may become dispensable for tumor maintenance,whereas mutant-PDGFRA is potently ***,our results open novel research avenues in deadly tumors.G34R/V gliomas are neuronal malignancies where interneuron progenitors are stalled in differentiation by G34R/V mutations and malignant gliogenesis is promoted by co-option of a potentially targetable pathway,PDGFRA signaling.

关键词： PDGFRA specificity connecting

天然变形的深变质长英质岩石中相边界的活动性:扩散蠕变的证据

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地质科学译丛 1993年第1期10卷 17-23页

作者： Robert j.W.Gower carol Simpson 宋媛 Department of Earth and Planetary Sciences the Johns Hopkins University Baltimore MD21218 USA

引言显微构造分析的目的之一,是辨别在变形时或其后控制岩石的相和颗粒边界的形成和运动的颗粒尺度的过程.同构造的颗粒边界运动或动态结晶的结构证据已在实验和天然变形的矿物中认出.一般认为这种重结晶是一个守恒过程,通过材料单矿物... 详细信息

引言显微构造分析的目的之一,是辨别在变形时或其后控制岩石的相和颗粒边界的形成和运动的颗粒尺度的过程.同构造的颗粒边界运动或动态结晶的结构证据已在实验和天然变形的矿物中认出.一般认为这种重结晶是一个守恒过程,通过材料单矿物区的颗粒边界的形成和迁移在化学成分和晶体构造方面仅有轻微的变化.但是,地球化学研究表明,在许多天然变形中,化学引起的物质转移是普遍的.它将会造成颗粒形态组构,这不仅是等化学的动态重结晶,而且也是由于颗粒尺度的反应和扩散所造成的.

关键词：长英质岩石深变质相边界蠕变

Energy modeling and data structure framework for Sustainable Human-Building Ecosystems （SHBE）- a review

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Frontiers in Energy 2018年第2期12卷 314-332页

作者： Suraj.TALELE Caleb TRAYLOR Laura ARPAN Cali CURLEY Chien-Fei CHEN j.lia DAY Richard FEIOCK mirsad HADZIKADIC William j. TOLONE Stan INGmAN Dale YEATTS Omer T. KARAGUZEL Khee Poh LAm carol mENASSA Svetlana PEVNITSKAYA Thomas SPIEGELHALTER Wei YAN Yimin ZHU Yong X. TAO Department of mechanical and Energy Engineering University of North Texas Denton Texas 76203 USA College of Communication & Information Florida State University Tallahassee FL 32306 USA School of Public and Environmental Affairs Indiana University-Purdue University Indianapolis Indianapolis 1N 46202 USA Department of Sociology University of Tennessee Knoxville Knoxville TN 37996 USA Human Ecology Department of Construction Management Washington State University Pullman WA 99164 USA Reubin O'D. Askew School of Public Administration and Policy Florida State University Tallahassee FL 32306 USA College of Computing and Informatics University of North Carolina Charlotte Charlotte NC 28223 USA Department of Gerontology University of North Texas Denton TX 76203 USA Department of Gerontology and Department of Sociology University of North Texas Denton TX 76203 USA CmU School of Architecture Carnegie Mellon University Pittsburgh PA 15213 USA School of Design & Environment National University of Singapore Singapore 117566 Singapore Department of Civil and Environmental Engineering University of Michigan Ann Arbor MI 48109 USA Department of Economics Florida State University Tallahassee FL 32306 USA Department of Architecture Florida Intemational University Miami FL 33199 USA College of Architecture Texas A & M University College Station TX 77843 USA Bert S. Turner Department of Construction management Louisiana State University Baton Rogue LA 70803 USA College of Engineering and Computing Nova Southeastern University Davie FL 33314 USA

This paper contributes an inclusive review of scientific studies in the field of sustainable human building ecosystems （SHBEs）. Reducing energy consumption by making buildings more energy efficient has been touted as an easily attainable approach to promoting carbon-neutral energy societies. Yet, despite significant progress in research and technology development, for new buildings, as energy codes are getting more stringent, more and more technologies, e.g., LED lighting, VRF systems, smart plugs, occupancy-based controls, are used. Nevertheless, the adoption of energy efficient measures in buildings is still limited in the larger context of the developing countries and middle income/low-income population. The obj.ctive of Sustainable Human Building Ecosystem Research Coordination Network （SHBE-RCN） is to expand synergistic investigative podium in order to subdue barriers in engineering, architectural design, social and economic perspectives that hinder wider application, adoption and subsequent performance of sustainable building solutions by recognizing the essential role of human behaviors within building-scale ecosystems. Expected long-term outcomes of SHBE-RCN are collaborative ideas for transformative technologies, designs and methods of adoption for future design, construction and operation of sustainable buildings.

关键词： sustainability building energy modeling(BEm) occupant behaviors (OB) sustainable ecosystems System for the Observation of Populous Heterogeneous Information (SOPHI)

缺钾对粗柠檬叶片氨、精氨酸和丁二胺含量及代谢变化的影响

维普期刊数据库评论

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上海农业学报 1996年第2期12卷 54-61页

作者：郑玉生张智奇 Lovatt carol j 湖南农业大学园艺系上海市农业科学院作物育种栽培研究所加利福尼亚大学河边分校植物科学系

缺钾对粗柠檬幼苗鲜重和干重均较正常供钾植株减少了４倍（Ｐ＜０．００１）。连续８个月对最新展开叶的氨代谢分析结果显示：缺钾植株叶片氨含量比对照高２．５倍（Ｐ＜０．００１）；精氨酸代谢加强，游离精氨酸浓度增加比对照高３．... 详细信息

缺钾对粗柠檬幼苗鲜重和干重均较正常供钾植株减少了４倍（Ｐ＜０．００１）。连续８个月对最新展开叶的氨代谢分析结果显示：缺钾植株叶片氨含量比对照高２．５倍（Ｐ＜０．００１）；精氨酸代谢加强，游离精氨酸浓度增加比对照高３．５倍（Ｐ＜０．００１）；游离脯氨酸校对照高１．６倍，而丁二胺含量增加了１０倍；缺钾条件下叶片精氨酸脱羧酶活性增强。

关键词：缺钾氨精氨酸脱羧酶精氨酸丁二胺柠檬