检索结果-南通市图书馆

World Journal of AIDS 2013年第1期3卷 41-56页

作者： Josefina J. Card, Emily N. Newman Emily N. Newman Rachel E. Golden Tamara Kuhn carmela lomonaco Sociometrics Corporation Los Altos USA Sociometrics Corporation Los Altos USA.

This paper describes the development, content, and capabilities of the online Global HIV Archive (GHA). With the goal of facilitating widespread adaptation and appropriate use of efficacious HIV prevention programs throughout the globe, GHA has: 1) expanded and updated the search for HIV prevention programs originating in low-resource countries;2) identified those meritorious HIV prevention programs meeting established efficacy criteria of technical merit, replicability, and positive outcomes;3) prepared both implementation and evaluation materials from the efficacious programs for public use;4) developed interactive wizards or capacity-building tools to facilitate appropriate program selection, implementation, and adaptation;5) made the efficacious programs and accompanying wizards available to health practitioners throughout the globe in both printed and online formats.

关键词： HIV Evidence-Based Intervention Prevention Dissemination International

Continuous non-invasive hemoglobin monitoring in pediatric trauma setting

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatric Surgery 2023年第4期6卷 203-205页

作者： Antonio Romanelli Rosanna carmela De Rosa Department of Anaesthesia and Intensive Care University Hospital'San Giovanni di Dio e Ruggi d’Aragona'SalernoItaly Department of Anaesthesia and Intensive Care Cotugno HospitalNaplesItaly

Trauma is the leading cause of death in pediatric patients,and hemorrhagic shock accounts for approximately 30% of deaths.12 Hemodynamic instability as hypotension and tachycardia,tachypnea,and alterations in mental s... 详细信息

关键词： pediatric alterations tachycardia

Isolated IgG4-associated autoimmune hepatitis or the first manifestation of IgG4-related disease?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2023年第4期22卷 415-417页

作者： carmela Cosentino Daniel Clayton-Chubb Catriona McLean Stuart K Roberts William Kemp Department of Gastroenterology and Hepatology Alfred HealthMelbourne 3004VICAustralia Central Clinical School Monash UniversityMelbourne 3004VICAustralia Department of Anatomical Pathology Alfred HealthMelbourne 3004VICAustralia

To the Editor:Immunoglobulin G4(IgG4)-associated autoimmune hepatitis(IgG4-AIH)is a novel and rare disease entity,characterized by sig-nificant infiltration of IgG4-expressing plasma cells in the *** classification of of IgG4-AIH as a subtype of AIH or an early manifestation of IgG4-related disease(IgG4-RD)remains ***,we discuss an interesting clinical vignette of IgG4-AIH in a gentleman with no significant past medical history,who presented with undifferentiated symptoms and elevated aminotransferases.

关键词： IgG4 AIH autoimmune

Squarefree Monomial Modules and Extremal Betti Numbers

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Algebra Colloquium 2016年第3期23卷 519-530页

作者： Marilena Crupi carmela Ferro University of Messina Department of Mathematics and Computer Science Viale Ferdinando Stagno d'Alcontres 31 Messina 98166 Italy

Let K be a field and let S = K[x1,...,xn] be a polynomial ring over K. Let F = ir=1 Sei be a finitely generated graded free S-module with basis {e1,..., er} in degrees f1,..., fr such that f1≤ f2 ~≤……≤ fr. We examine some classes of squarefree monomial submodules of F. Hence, we focalize our attention on the Betti table of such classes in order to analyze the behavior of their extremal Betti numbers.

关键词： graded modules squarefree monomial modules minimal graded resolutions

Silybin and the liver: From basic research to clinical practice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第18期17卷 2288-2301页

作者： carmela Loguercio Davide Festi Gastroenterology School-Interuniversity Research Centre on Foods Nutrition and Gastrointestinal Tract (CIRANAD) 2nd University of Naples Department of Clinical Medicine University of Bologna

Herbal products are increasingly used, mainly in chronic liver disease. Extracts of milk thistle, Silymarin and silybin, are the most prescribed natural compounds, with different indications, but with no definitive results in terms of clinical efficacy. This review analyzes the available studies on the effects of the purified product silybin, both as a free and a conjugated molecule, on liver cells or on experimentally induced liver damage, and in patients with liver disease. We searched PUBMED for articles pertaining to the in vitro and in vivo effects of silybin, its antifibrotic, anti-inflammatory, and antioxidant properties, as well as its metabolic effects, combined with the authors’ own knowledge of the literature. Results indicate that the bioavailability of silybin phytosome is higher than that of silymarin and is less influenced by liver damage; silybin does not show significant interactions with other drugs and at doses < 10 g/d has no significant side effects. Experimental studies have clearly demonstrated the antifibrotic, antioxidant and metabolic effects of silybin; previous human studies were insufficient for confirming the clinical efficacy in chronic liver disease, while ongoing clinical trials are promising. On the basis of literature data, silybin seems a promising drug for chronic liver disease.

关键词：水飞蓟宾基础研究临床实践肝脏 PubMed 水飞蓟素临床疗效肝纤维化

Human retinal secretome:A cross-link between mesenchymal and retinal cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2023年第7期15卷 665-686页

作者： Luigi Donato Concetta Scimone Simona Alibrandi Sergio Zaccaria Scalinci Domenico Mordà carmela Rinaldi Rosalia D'Angelo Antonina Sidoti Department of Biomedical and Dental Sciences and Morphofunctional Imaging University of MessinaMessina 98125Italy Department of Biomolecular Strategies Genetics and Cutting-Edge TherapiesEuro-Mediterranean Institute of Science and TechnologyPalermo 90139Italy Department of Chemical BiologicalPharmaceutical and Environmental SciencesUniversity of MessinaMessina 98125Italy Department of Medical and Surgical Sciences University of BolognaBologna 40121Italy

In recent years,mesenchymal stem cells(MSC)have been considered the most effective source for regenerative medicine,especially due to released soluble paracrine bioactive components and extracellular *** factors,collectively called the secretome,play crucial roles in immunomodulation and in improving survival and regeneration capabilities of injured ***,there has been a growing interest in the secretome released by retinal cytotypes,especially retinal pigment epithelium and Müller glia *** latter trophic factors represent the key to preserving morphofunctional integrity of the retina,regulating biological pathways involved in survival,function and responding to ***,these factors can play a pivotal role in onset and progression of retinal diseases after damage of cell secretory *** this review,we delineated the importance of cross-talk between MSCs and retinal cells,focusing on common/induced secreted factors,during experimental therapy for retinal *** cross-link between the MSC and retinal cell secretomes suggests that the MSC secretome can modulate the retinal cell secretome and vice *** example,the MSC secretome can protect retinal cells from degeneration by reducing oxidative stress,autophagy and programmed cell ***,the retinal cell secretome can influence the MSC secretome by inducing changes in MSC gene expression and phenotype.

关键词： Secretome Mesenchymal stem cells Retinal cells Extracellular vesicles Retinal diseases

Grain boundary boosting the thermal stability of Pt/CeO_(2)thin films

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2023年第2期16卷 3278-3286页

作者： Luyao Wang Xiaobao Li Xiangchen Hu Shuyue Chen Zhehao Qiu Yifan Wang Hui Zhang Yi Yu Bo Yang Yong Yang Pasquale Orgiani carmela Aruta Nan Yang Electrochemical thin film group School of physical science and technologyShanghaiTech UniversityShanghai 201210China State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China School of physical science and technology ShanghaiTech UniversityShanghai 201210China CNR-IOM TASC National LaboratoryI-34149 TriesteItaly CNR-SPIN UOS RomaArea della Ricerca di Tor VergataRome I-00133Italy

Understanding how defect chemistry of oxide material influences the thermal stability of noble metal dopant ions plays an important role in designing high-performance heterogeneous catalytic *** we use in-situ ambient-pressure X-ray photoemission spectroscopy(APXPS)to experimentally determine the role of grain boundary in the thermal stability of platinum doped cerium oxide(Pt/CeO_(2)).The grain boundaries were introduced in Pt/CeO_(2)thin films by pulsed laser deposition without significantly change of the surface *** defect level was tuned by the strain field obtained using a highly/low mismatched *** Pt/CeO_(2)thin film models having well defined crystallographic properties but different grain boundary structural defect levels provide an ideal platform for exploring the evolution of Pt–O–Ce bond with changing the temperature in reducing *** have direct demonstration and explanation of the role of Ce^(3+)induced by grain boundaries in enhancing Pt2+*** observe that the Pt^(2+)–O–Ce^(3+)bond provides an ideal coordinated site for anchoring of Pt^(2+)ions and limits the further formation of oxygen vacancies during the reduction with H_(2).Our findings demonstrate the importance of grain boundary in the atomic-scale design of thermally stable catalytic active sites.

关键词： platinum doped cerium oxide(Pt/CeO_(2)) pulsed laser deposition epitaxial thin films grain boundaries defect engineering in-situ ambient-pressure X-ray photoemission spectroscopy

Fungal spores and pollen in particulate matter collected during agricultural activities in the Po Valley(Italy)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2016年第8期28卷 229-240页

作者： Chiara Telloli Milvia Chicca Marilena Leis carmela Vaccaro Italian National Agency for New Technologies Energy and Sustainable Economic Development (ENEA) Technical Unit for Environmental Assessment Models Methods and Technologies (UTVALAMB) Air Quality Laboratory (AIR) Department of Life Science and Biotechnologies Ferrara University Department of Physics and Earth Sciences Ferrara University

Airborne particulate matter（PM） containing fungal spores and pollen grains was sampled within a monitoring campaign of wheat threshing, plowing and sowing agricultural operations. Fungal spores and pollen grains were detected and identified on morphological basis. No studies were previously available about fungal spore and pollen content in agricultural PM in the Po Valley. Sampling was conducted in a Po Valley farmland in Mezzano（Ferrara, Italy）. The organic particles collected were examined by scanning electron microscopy with energy dispersive X-ray spectrometer. Fungal spores and pollen grains were identified when possible at the level of species. The most frequent components of the organic particles sampled were spores of Aspergillus sp., which could represent a risk of developing allergies and aspergillosis for crop farmers.

关键词： Wheat Aspergillosis Emilia-Romagna Morphology SEM–EDS

Improved lifestyle is associated with improved depression,anxiety and wellbeing over time in UK healthcare professionals during the COVID-19 pandemic:insights from the CoPE-HCP cohort study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

综合精神医学(英文) 2023年第1期36卷 19-27页

作者： Mohammed Y Khanji George Collett Thomas Godec carmela Maniero Sher May Ng Imrana Siddiqui Jaya Gupta Vikas Kapil Ajay Gupta William Harvey Research Institute Queen Mary University of LondonLondonUK Department of Cardiology Barts Heart CentreSaint Bartholomew's HospitalBarts Health NHS TrustLondonUK Newham University Hospital Barts Health NHS TrustLondonUK Wellbeing Hub Newham Training HubLondonUK NHS North East London CCG LondonUK Child and Adolescent Mental Health Service South West London and St George's Mental Health NHS TrustLondonUK

Background One potential modifiable factor to improve the mental health of healthcare professionals(HCPs)during the pandemic is *** This study aimed to assess whether an improved lifestyle during the pandemic is associated with improved mental health symptoms and mental well-being in HCPs over *** This was a cohort study involving an online survey distributed at two separate time points during the pandemic(baseline(July–September 2020)and follow-up(December 2020–March 2021))to HCPs working in primary or secondary care in the *** surveys assessed for major depressive disorder(MDD)(Patient Health Questionnaire-9(PHQ-9)),generalised anxiety disorder(GAD)(Generalised Anxiety Disorder-7(GAD-7)),mental well-being(Short Warwick-Edinburgh Mental Well-being Score(SWEMWBS))and self-reported lifestyle change(compared with the start of the pandemic)on multiple *** scores were calculated to estimate overall lifestyle change compared with that before the pandemic(at both baseline and follow-up).At each time point,separate logistic regression models were constructed to relate the lifestyle change score with the presence of MDD,GAD and low mental *** regression models were also developed relating the change in lifestyle scores from baseline to follow-up to changes in PHQ-9,GAD-7 and SWEMWBS *** 613 HCPs completed both baseline assessment and follow-up *** significant cross-sectional associations between increased lifestyle change scores and a reduced risk of MDD,GAD and low mental well-being were observed at both baseline and *** the study period,a whole unit increase in the change in novel scores(ie,improved overall lifestyle)over 4 months was inversely associated with changes in PHQ-9(adjusted coefficient:−0.51,95%confidence interval(CI):−0.73 to−0.30,p<0.001)and GAD-7 scores(adjusted coefficient:−0.32,95%CI:−0.53 to−0.10,p=0.004)and positively associated with the change in SWEMWBS scores

关键词： Edinburgh lifestyle coefficient

Investigations of a nanostructured FeMnSi shape memory alloy produced via severe plastic deformation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2016年第11期23卷 1315-1322页

作者： Gheorghe Gurau carmela Gurau Vedamanickam Sampath Leandru Gheorghe Bujoreanu Faculty of Engineering "Dun?rea de Jos" University of Galati Department of Metallurgical and Materials Engineering Indian Institute of Technology Madras Faculty of Materials Science and Engineering "Gheorghe Asachi" Technical University of Ia?i

Low-cost iron-based shape memory alloys（SMAs） show great potential for engineering applications. The developments of new processing techniques have recently enabled the production of nanocrystalline materials with improved properties. These developments have opened avenues for newer applications for SMAs. The influence of severe plastic deformation induced by the high-speed high-pressure torsion（HSHPT） process on the microstructural evolution of an Fe–Mn–Si–Cr alloy was investigated. Transmission electron microscopic analysis of the alloy revealed the existence of nanoscale grains with an abundance of stacking faults. The high density of dislocations characteristic of severe plastic deformation was not observed in this alloy. X-ray diffraction studies revealed the presence of ε-martensite with an HCP crystal structure and γ-phase with an FCC structure.

关键词： iorn manganese silicon alloys shape memory effect nanostructured materials martensite plastic deformation