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Navigating Chinese cities to achieve sustainable development goals by 2030

The Innovation 2022年第5期3卷 114-121页

作者： Huijuan Xiao Zhenci Xu Jingzheng Ren Ya Zhou Ruojue Lin Sheng Bao Long Zhang Shengfang Lu carman k.m.lee Jianguo Liu Department of Industrial and Systems Engineering The Hong Kong Polytechnic UniversityHong Kong SARChina Department of Geography The University of Hong KongHong Kong SARChina Peng Cheng Laboratory Shenzhen 518000China key Laboratory for City Cluster Environmental Safety and Green Development of the ministry of Education School of EcologyEnvironment and ResourcesGuangdong University of TechnologyGuangzhou 510006China Otto Poon C.F.Smart Cities Research Institute Department of Land Surveying and Geo-InformaticsThe Hong Kong Polytechnic UniversityHong Kong SARChina Center for Systems Integration and Sustainability Department of Fisheries and WildlifeMichigan State UniversityEast LansingMI 48824USA Southern marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou511458China

Achieving the 17 United Nations sustainable development goals(SDGs)in China largely depends on the transition of cities toward sustainable ***,significant knowledge gaps exist in evaluating the SDG index at the city scale and in understanding how to simulate pathways to achieve the 17 SDGs for Chinese cities by *** study aimed to quantify the SDG index of 285 Chinese cities and developed a forecasting model to simulate the performance of each SDG in each city until 2030 using varied *** results indicated that although the SDG index in Chinese cities increased by 33.97%during 2005–2016,Chinese cities,which continued their past paths,achieved an average of only five SDGs by *** promote the joint achievement of all SDGs,we designed different paths for all SDGs of each of the 285 cities and simulated their SDG index until *** the scenarios,216 Chinese cities(75.79%)could achieve 9–13 more SDGs in 2030 and the overall SDG index can improve from 74.57 in 2030 to 97.49(target score 100)by adopting more intensive path *** lastly determined a cost-effective path for each SDG of each city to promote joint achievement of all SDGs by *** proposed simulation model and cost-effective path serve as a foundation for other countries to simulate SDG progress and develop pathways for achieving SDGs in the future.

关键词： sustainable continued goals

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The discovery of the fat-regulating phosphatidic acid phosphatase gene

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Frontiers in Biology 2011年第3期6卷 172-176页

作者： George m.carman Department of Food Science and Rutgers Center for Lipid Research Rutgers UniversityNew BrunswickNew Jersey 08901U.S.A.

Phosphatidic acid phosphatase is a fat-regulating enzyme that plays a major role in controlling the balance of phosphatidic acid(substrate)and diacylglycerol(product),which are lipid precursors used for the synthesis of membrane phospholipids and *** acid is also a signaling molecule that triggers phospholipid synthesis gene expression,membrane expansion,secretion,and *** this important enzyme has been known for several decades,its gene was only identified recently from *** discovery showed the importance of phosphatidic acid phosphatase in lipid metabolism in yeast as well as in higher eukaryotes including humans.

关键词： phosphatidic acid phosphatase yeast lipin phospholipid triacylglycerol

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Differential reactivity of mouse monoclonal anti-HBs antibodies with recombinant mutant HBs antigens

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World Journal of Gastroenterology 2006年第33期12卷 5368-5374页

作者： Azam Roohi Yaghoub Yazdani Jalal khoshnoodi Seyed mohammad Jazayeri William F carman mahmood Chamankhah manley Rashedan Fazel Shokri Department of Immunology School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Virology School of Public Health Tehran University of Medical Sciences Tehran Iran Division of Virology Institute of Biomedical and Life Science University of Glasgow Glasgow United Kingdom monoclonal Antibody Research Center Avesina Research Center Tehran Iran

AIm: To investigate the reactivity of a panel of 8 mouse anti-hepatitis B surface antigen (HBsAg) monoclonal antibodies (mAbs) using a collection of 9 recombinant HBsAg mutants with a variety of amino acid substitutions mostly located within the “a” ***: The entire HBs genes previously cloned into a mammalian expression vector were transiently transfected into COS7 cells. Two standard unmutated sequences of the ayw and adw subtypes served as controls. Secreted mutant proteins were collected and measured by three commercial diagnostic immunoassays to assess transfection efficiency. Reactivity of anti-HBs mAbs with mutated HBsAgs was determined by sandwich enzyme-linked immunosorbent assay (ELISA).RESULTS: Reactivity of anti-HBs mAbs with mutated HBsAgs revealed different patterns. While three mutants reacted strongly with all mAbs, two mutants reacted weakly with only two mAbs and the remaining proteins displayed variable degrees of reactivity towards different mAbs. Accordingly, four groups of mAbs with different but overlapping reactivity patterns could be envisaged. One group consisting of two mAbs (37C5-S7 and 35C6-S11) was found to recognize stable linear epitopes conserved in all mutants. mutations outside the “a” determinant at positions 120 (P→S), 123(T→N) and 161(m→T) were found to affect reactivity of these ***: Our findings could have important implications for biophysical studies, vaccination strategies and immunotherapy of hepatitis B virus (HBV) mutants.

关键词： Hepatitis B surface antigen Hepatitis B virus mutant Epitope mapping Vaccination monoclonal antibody

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Histopathological Investigation of the Stomach of Rats Fed a 60% Genetically modified Corn Diet

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Food and Nutrition Sciences 2018年第6期9卷 763-796页

作者： Irena m. Zdziarski Judy A. carman John W. Edwards Discipline of Anatomy and Pathology School of Medicine University of Adelaide Australia The Institute of Health and Environmental Research (IHER) Kensington Park Australia Health and Environment College of Science and Engineering Flinders University Bedford Park Australia

Genetic modification (Gm) represents new opportunities for enhanced crop features such as improved insect resistance and herbicide tolerance. The technology allows for cross-species alterations, therefore potentially allowing a vast array of novel traits. many Gm crops have been developed and approved for human and animal consumption. The present study investigated a triple-stacked Gm corn variety containing modifications for insect resistance (via cry1Ab and cry3Bb1 genes) and herbicide tolerance (via an EPSPS gene), which was fed to rats for six months. The study investigated the mucosa of the stomach. Alterations to tight junction apposition, gland dilatations with epithelial elongation and dysplasia in the Gm-fed rats were observed. These results indicate that Gm-corn may have an effect on rat stomach mucosa, which may have health implications.

关键词： Genetically modified Corn Rat Feeding Study Long-Term Feeding Study Histopathology Stomach

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暴风雨对波罗的本海西北部深海地区沉积物积累和纹层沉积的影响

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AmBIO－人类环境杂志 2000年第4期29卷 237-245页

作者： JanEckhéll Per Jonsson markus meili Rolf carman 王燕乌普萨拉大学瑞典环境保护局斯德哥尔摩大学

波罗的本海地表纹层沉积物的形成不断扩大的现象为我们评价过去40年里沉积物积累的年际变化增加了可能性。同一时期,在Gotska Sand(?)n我们连续记载了这个地区的风速和风向。在39km^2范围内,收集了55个岩心,从中选取了3个具有明显纹层... 详细信息

波罗的本海地表纹层沉积物的形成不断扩大的现象为我们评价过去40年里沉积物积累的年际变化增加了可能性。同一时期,在Gotska Sand(?)n我们连续记载了这个地区的风速和风向。在39km^2范围内,收集了55个岩心,从中选取了3个具有明显纹层的沉积物岩心,对它们的细微结构进行了研究,结果发现,干物质的年累积量和大风出现的频率正相关,风力达到14m/s时,两者关系为最佳。这证实了再次悬浮的沉积物在沉积物积累中占很大比重的观点,在115～145m深处收集的25个地表纹层的岩心,其沉积物积累的平均速率为2mm/a。我们对暴风雨发生的频率和沉积物沉积在10年间的变化都进行了观测,两者的变化可能不仅说明了沉积物及有关营养物和污染物的周转,而且还使我们能用沉积物岩心作为历史档案库来做一些解释。对所有岩心中已确定年代的沉积层进行水平方向的比较揭示了深水条件下物质变化的情况。最近,海底动物群再次大面积定居在水深102～125m范围内的现象说明,90年代早期的暴风雨事件极大地提高了氧的条件。尽管在我们的样品中纹层沉积物生物搅动的深度范围在0.5～5.5cm,但却造成了氧条件很早就已经提高了的假象。

关键词：暴风雨波罗的海深海地区沉积物纹层沉积

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白垩纪末期生物大批死亡引起的环境变化及其演化意义

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吉林大学学报（地球科学版） 1982年第1期25卷 1-14页

作者：许靖华何起祥 J.A.mckenzie H.Weissert k.Perch-Nielsen H.Oberhnsli k.kelts J.LaBrecque U.krhenbühl S.F.Percival R.Wright R.Z.Poore A.m.Gombos k.Pisciotto A.m.karpoff N.Petersen P.Tucker m.F.carman E.Schreiber

DSDP 524区中生代最晚期和第三纪最早期的沉积物中,保存着白垩纪末期环境变化和生物演化的详细纪录。我们对该孔进行了加密取样,样品间距大致相当于100年或1000年的时间间隔,同时对样品进行了碳酸盐含量、微量元素成分及碳氧同位素分析... 详细信息

DSDP 524区中生代最晚期和第三纪最早期的沉积物中,保存着白垩纪末期环境变化和生物演化的详细纪录。我们对该孔进行了加密取样,样品间距大致相当于100年或1000年的时间间隔,同时对样品进行了碳酸盐含量、微量元素成分及碳氧同位素分析。我们所得到的数据可以解释为白垩纪末期生物大批死亡的结果,当时大量远洋地区的生物扫地以尽。养料锐减导致部分从河流带来的溶解CO_2转移到大气圈,致使在长达40,000年的时间内,空气中的CO_2剧增。由此产生的温室效应就是氧同位素所揭示的温度升高的原因。第三纪最早期沉积物中,包括来自“白垩纪生物群”中的化石,有的已经过再沉积作用,有的则是这场灾难的最后幸存者。我们的资料表明,大量远洋生物的灭绝是在第三纪最早期的不利环境中发生的。而这种异常的环境则是生物大批死亡的结果,且持续有几千年之久。恐龙就是因为温度灾难性升高产生的热异常而灭绝的。大洋中生物大批灭绝的原因,与巨大的天外星体的陨落有关,界线附近的铱异常即其标志,我们的资料与许靖华不久前发表的彗星冲击说是不抵触的。

关键词：环境变化碳氧同位素碳同位素碳酸盐含量许靖华大气圈半深海沉积过渡带铱异常有孔虫化石

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