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World Journal of Cardiology 2012年第1期4卷 15-19页

作者： Lorenzo Fácila Pedro Morillas Juan Quiles Federico soria Alberto Cordero Pilar Mazón Manuel Anguita Cándido Martín-Luengo Jose Ramón Gonzalez-Juanatey Vicente Bertomeu Department of Cardiology Consorcio Hospitalario General de Valencia Department of Cardiology Hospital Universitario de San Juan Department of Cardiology Hospital Virgen de la Arrixaca Department of Cardiology Hospital Clínico Universitario Santiago de Compostela Department of Cardiology Hospital Reina Sofía Department of Cardiology Hospital Universitario de Salamanca

AIM: To investigate the prognostic significance of resting heart rate in patients with acute coronary syndrome (ACS), independent of other known factors. METHODS: Patients 40 years of age or older who had been admitted with acute coronary syndrome (ACS) to one of the 94 hospitals participating in the Prevalence of Peripheral Arterial Disease in Patients with Acute Coronary Syndrome (PAMISCA) study were included. Patients were divided into two groups based on their resting heart rate (HR ≥ or < 70 bpm). Complications were recording during a follow-up period of 1 year. RESULTS: There were 1054 ACS patients analyzed (43.5% with ST segment elevation and 56.5% without elevation). Mean age was 66.6 ± 11.7 years, 70.6% were male and 29.4% of subjects were female. During follow-up, more patients in the HR ≥ 70 bpm group were hospitalized for heart failure and they also had a higher mortality rate. In the multivariate analysis, a heart rate of ≥ 70 bpm was independently related to overall mortality during the follow-up period (hazard ratio 2.5; 95% confidence interval, 1.26-4.97, P = 0.009). CONCLUSION: A resting heart rate ≥ 70 bpm in patients who survive an ACS is an indicator of a high risk of suffering cardiovascular events during follow-up.

关键词： Heart rate Myocardial infarction Prognosis

Flora and Vegetation Associated with <i>Dichromanthus cinnabarinus</i>(La Llave &Lex.) Garay (Orchidaceae, Spiranthinae) in Northeastern Mexico

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Natural Science 2020年第8期12卷 599-619页

作者： Elba Zarahy Garay-Martínez Jacinto Treviño-Carreón Tania Judith Hernández-López Juana María Coronado-Blanco Claudia C. Astudillo Sánchez Leroy soria-Díaz Arturo Mora Olivo Universidad Autónoma de Tamaulipas Facultad de Ingeniería y Ciencias Centro Universitario Adolfo López Mateos Ciudad Victoria Ciudad Victoria México Instituto de Ecología Aplicada Universidad Autónoma de Tamaulipas División del Golfo Col. Libertad Ciudad Victoria Tamaulipas México

Studies conducted in northeastern Mexico have not provided information on the flora and vegetation associated with Dichromanthus cinnabarinus. Therefore, it is necessary to study the areas where this orchid is distributed to understand the plant vegetation interaction. Research questions: What plant species are associated with Dichromanthus cinnabarinus? What is the degree of similarity among the plant communities with which Dichromanthus cinnabarinus is associated? Study site: Northeastern Mexico, comprehending the states of Coahuila, Nuevo Leon and Tamaulipas. Methods: The study sites were selected consider-ing the presence of Dichromanthus cinnabarinus. Regarding the study of the plant struc-ture, the tree, shrub, and herbaceous strata were obtained by the methodology of quad-rants. Data were collected in April and August 2017. The results were analyzed using the Importance Value Index (IVI) for each stratum present and a Parsimony Analysis of En-demicity (PAE) for the plant communities. Results: In the study area, a total of 33 families, 60 genera and 69 species were registered. The representative families are Asteraceae with eight species, Asparagaceae with six, Fabaceae with five, followed by Cactaceae, Poaceae and Roasaceae with four species each. Regarding endemic species, a total of 11 species distributed in nine genera were registered in the study sites. Conclusions: In northeastern Mexico, Dichromanthus cinnabarinus is found associated with Aristida adscensionis L., Agave lechuguilla Torr. Bouteloua sp., Euphorbia antisyphilitica Zucc., Agave striata var. striata (Salm-Dyck) and Rhus virens Lindh. ex A. Gray. Moreover, Dichromanthus cin-nabarinus is observed in some sites with contrasting flora, according to the resulting list of endemic species. It is important to establish priority areas for wildlife conservation in northeastern Mexico.

关键词： Northeastern Mexico Flora Vegetation Endemism

The LALF32-51 peptide as component of HPV therapeutic vaccine circumvents the alum-mediated inhibition of IL-12 and promotes a Th1 response

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The LALF32-51 peptide as component of HPV therapeutic vaccin...

第十四届全国肿瘤生物治疗大会

作者： Milaid Granadillo Alain B. Alfonso Maribel G. Vallespi Aileen Batte Yordanka soria Enma Brown Miladys Limonta Yayrí C. Prieto Laura Varas Isis Torrens Center for Genetic Engineering and Biotechnology Department of Cancer Center for Genetic Engineering and Biotechnology Animal Care Unit Center for Genetic Engineering and Biotechnology Technological Development Unit

Aluminum-containing adjuvants(alum) continue to be the most widely used adjuvants. It is common knowledge that these adjuvants predominantly induce humoral immunity, but some reports also describe their role combined with IL-12 in the induction of a Th1 immune *** this study we want to investigate if alum could be an adjuvant to be used as a component of a therapeutic vaccine that require the generation of cell-mediated immunity. To demonstrate this concept we selected the human papillomavirus(HPV) 16-transformed mouse TC-1 cells as model and the fusion protein LALF32-51-E7 as antigen. Our results suggest that LALF32-51-E7 combined with aluminum hydroxide adjuvant promotes a Th1 immune response and consequently an anti-tumor response in the TC-1 tumor model. These results could have important application in future clinical trials in women with low grade squamous intraepithelial neoplasia.

关键词： Adjuvant Alum Al(OH)3 Fusion protein LALF32-51-E7

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新型冷轧润滑液——微乳液

轧钢 1989年第2期6卷 57-60页

作者： C.soria E.Brandolese R.Zonza C.Gualco 范坚祥意大利AGIPPETROLI公司意大利EURON公司意大利冶金公司新利古里亚厂

冷轧乳液的性能可沿两个途径改善:一是增加乳液自身的稳定性,从而获得更为有效的润滑性能与更佳的轧制效率;二是采用能够减少在轧件上形成沉积物的适宜组分,从而使退火后板卷表面的碳渣量减至最少。如果上述两种途径兼而用之,则可获得... 详细信息

冷轧乳液的性能可沿两个途径改善:一是增加乳液自身的稳定性,从而获得更为有效的润滑性能与更佳的轧制效率;二是采用能够减少在轧件上形成沉积物的适宜组分,从而使退火后板卷表面的碳渣量减至最少。如果上述两种途径兼而用之,则可获得更优的效果。这就是说,这种润滑液将是一种含有合成酯类的非常稳定的微乳液,其沸点范围狭窄,产生的碳渣量少,使金属表面的沉积物与污斑大为减少。

关键词：微乳液冷轧润滑液乳液

Efficacy and safety of sphincterotomy with sphincteroplasty using large caliber balloons in the treatment of choledocholithiasis with extraction difficulties

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Open Journal of Gastroenterology 2013年第4期3卷 241-248页

作者： R. Uribarrena-Amezaga I. Aured De La Serna I. Calvo-Morillas J. J. Sebastián-Domingo T. Cabrera-Chaves M. T. soria San Teodoro R. Uribarrena-Echebarría Department of Digestive Diseases Miguel Servet University Hospital Zaragoza Spain Department of Digestive Diseases Royo Villanova Hospital Zaragoza Spain

Introduction: Endoscopic retrograde cholangiopan-creatography (ERCP) with endoscopic sphincterotomy (ES) is the most widely used technique for treating choledocholithiasis. In some cases, due to anomalies of the papilla or the presence of large or multiple calculi, additional maneuvers are needed to remove the stones. The present study investigates the efficacy and safety of ES with sphincteroplasty (SP) in the management of choledocholithiasis with extraction difficulties. Patients and Methods: A prospective study was made of 153 patients with choledocholithiasis subjected to ERCP. Fifty-two patients underwent ES with SP, while 101 were subjected only to ES. The two groups were compared in terms of age, gender, percentage cannulation, presence of papilla alterations, large or multiple stones, success in stone removal and complications (acute pancreatitis, bleeding and perforation). In the ES with SP group, we moreover recorded the diameters of the balloons employed (10-18 mm). Results: There were no significant differences between the groups in the stone extraction success rate (94.23% in the ES with SP group versus 97.03% in the ES group) or in the appearance of complications (3.8% in the ES with SP group versus 2.7% in the ES group). The presence of difficult papillae, and of multiple or large stones was significantly greater in the ES with SP group. The diameter of the balloon was not associated with the appearance of complications. Conclusion: Endoscopic sphincterotomy with sphincteroplasty is effective and safe in the treatment of choledocholithiasis with extraction difficulties.

关键词： Choledocholithiasis Endoscopic Sphincterotomy Sphincteroplasty

A Summary, Insight and Autocriticism of Information Systems That We Have Developed for Medical Education

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A Summary, Insight and Autocriticism of Information Systems ...

2011 The Second International Conference on Information, Communication and Education Application（ICEA 2011）

作者： RIVAS-ECHEVERRíA carlos RIVAS-ECHEVERRíA Francklin MOLINA Lizmar GONZáLEZ Solange RIVAS Verónica Calle Manuel Fraga Iribarne 6 portal 14 ASoria42005Spain Urb. Sta. María sur calle Pico EspejoQTA MónicaMérida5101Venezuela

Along 24 years, our team in the University of Los Andes, Mérida-Venezuela, has developed several softwares intended to have educational applications in medicine. All of them were just prototypes and were never completed. We have always thought that information systems have a very important place in education and that in the future they would have a leading role. We have been thinking that the future paradigm of education is based on informatics, communications and their applications. Nevertheless, our insight and autocriticism has open new windows, points of view and approaches of this "new paradigm" and some questions have invaded our minds. Metaphorically speaking, are information systems applications a teacher, a model, a way, a mean, a goal? Or;might it be just a sort of a tool, comparable with a book;or even more dispensable ones like a pencil, a piece of paper, an eraser or a pencil-sharpener? In this paper we will briefly present some of our products(information systems), their features, applications, rationale, some difficulties that we have encountered while introducing them. We will describe the evolution of the new ideas and developments that we incorporated and finally we will discuss some of the thoughts that have emerged. Answers to these questions might be given by the readers.

关键词： Information Systems,Medical Diagnosis,Medical Education,Artificial Intelligence

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巴黎阿拉伯世界研究院

世界建筑导报 2006年第8期21卷 12-15页

作者： M.Robain R.Tisnado JF.Galmiche J.Nouvel G.Lezenes P.soria 法国AS.建筑工作室

Role of double-balloon enteroscopy in malignant small bowel tumors

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World Journal of Gastrointestinal Endoscopy 2015年第6期7卷 652-658页

作者： Enrique Pérez-Cuadrado Robles Pilar Esteban Delgado Paloma Bebia Conesa Blanca Martínez Andrés Milivoj Franulic Guggiana Eduardo Alcaraz Mateos Mariana Fernández Caballero José Luis Rodrigo Agudo Silvia Chacón Martínez Rafael Latorre Federico soria Juan Manuel Herrerías Gutiérrez Enrique Pérez-Cuadrado Martínez Department of Gastroenterology Morales Meseguer Hospital Department of Radiology Morales Meseguer Hospital Department of Pathology Morales Meseguer Hospital Department of Hematology and Oncology Morales Meseguer Hospital Department of Anatomy University of Murcia Centre Jesus Usón Hospital Universitario Virgen Macarena

AIM: To assess the double-balloon enteroscopy(DBE) role in malignant small bowel tumors(MSBT).METHODS: This is a retrospective descriptive study performed in a single center. All consecutive patients who underwent a DBE with final diagnosis of a malignant neoplasm from 2004 to 2014 in our referral center were included. Patient demographic and clinical pathological characteristics were recorded and reviewed. MSBT diagnosis was achieved either by DBE directed biopsy with multiple tissue sampling, endoscopic findings or histological analysis of surgical specimen. We have analyzed double-balloon enteroscopy impact in outcome and clinical course of these patients. RESULTS: Of 627 patients, 28(4.5%)(mean age = 60 ± 17.3 years) underwent 30 procedures(25 anterograde, 5 retrograde) and were diagnosed of a malignant tumor. Patients presented with obscure gastrointestinal bleeding(n = 19, 67.9%), occlusion syndrome(n = 7, 25%) and diarrhea(n = 1, 3.6%). They were diagnosed by DBE biopsy(n = 18, 64.3%), histological analysis of surgical specimen(n = 7, 25%) and unequivocal endoscopic findings(n = 2, 7.1%). Gastrointestinal stromal tumor(n = 8, 28.6%), adenocarcinoma(n = 7, 25%), lymphoma(n = 4, 14.3%), neuroendocrine tumor(n = 4, 14.3%), metastatic(n = 3, 10.7%) and Kaposi sarcoma(n = 1, 3.6%) were identified. DBE modified outcome in 7 cases(25%), delaying or avoiding emergency surgery(n = 3), modifying surgery approach(n = 2) and indicating emergency SB partial resection instead of elective approach(n = 2).CONCLUSION: DBE may be critical in the management of MSBT providing additional information that may be decisive in the clinical course of these patients.

关键词： Double balloon enteroscopy Malignantsmall bowel tumors Obscure gastrointestinal bleeding Gastrointestinal stromal tumor Occlusion syndrome

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甜瓜中一种由蚜虫传播的花叶病毒新抗源

国外作物育种 2004年第3期23卷 47-47页

作者： C.soria 向平

病毒病是造成甜瓜(Cucumis milo L.)严重产量损失的主要病害。侵害南瓜作物的病毒有50多种，其中黄瓜花叶病毒(CMV)、两瓜花叶病毒(WMV)、小西葫芦黄色花叶病毒(ZYMV)和番木瓜环斑病毒-W(PRSV—W)是甜瓜作物中最流行的病毒。培育抗性品... 详细信息

病毒病是造成甜瓜(Cucumis milo L.)严重产量损失的主要病害。侵害南瓜作物的病毒有50多种，其中黄瓜花叶病毒(CMV)、两瓜花叶病毒(WMV)、小西葫芦黄色花叶病毒(ZYMV)和番木瓜环斑病毒-W(PRSV—W)是甜瓜作物中最流行的病毒。培育抗性品种是防治病毒的最佳方法。

关键词：甜瓜蚜虫传播途径花叶病毒抗源