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International journal of Clinical Medicine 2012年第2期3卷 151-153页

作者： Helio A.Guimaraes filho janett j.Liberalino Ana T.P.Mendonca carlos V.S.B.Leite filho Leonardo f.felipe carlos f.melo júnior CETRIM-Imaginology Training Center Joao PessoaBrazil Departament of Ultrasound Frei Damiao MaternityJoao PessoaBrazil Department of Radiology Federal University of ParaibaJoao PessoaBrazil

Cerebral hemorrhages are fairly common in full-term neonates with no history of traumatic birth, mostly limited, and with benign evolution. We report a case of a full-term neonate from vaginal birth with caput succedaneum in the right parietal area. The neonate underwent cranial ultrasonography and color Doppler which showed extra-axial blood effusion. Color Doppler showed vessels crossing the collection area, which allowed the diagnosis of subarachnoid hematoma.

关键词： Cerebral Hemorrhage Subarachnoid Hematoma Cranial Ultrasound Color Doppler

functional Roux-en-Y Gastric Bypass (f-RYGB), with Preservation of Duodenal Access: Report of Two Revisional Cases of Sleeve Gastrectomy

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Surgical Science 2024年第3期15卷 135-158页

作者： Victor Ramos Mussa Dib carlos Augusto Scussel Madalosso Paulo Reis Esselin de melo Rui Ribeiro Paula Volpe carlos Eduardo Domene Victor Dib Institute Manaus Brazil Gastrobese Clinic Passo Fundo Brazil Paulo Reis Institute of Bariatric Surgery Goi&#226nia Brazil Alfredo Nasser University Center (UNIfAN) Goi&#226nia Brazil Lusíadas Amadora Hospital Lisboa Portugal Integrated Center for Advanced Medicine (CIMAMED) S&#227o Paulo Brazil

Objective: This case report aimed to demonstrate a possible neuromuscular effect of Latarjet nerves transection or truncal vagotomy, in association with sleeve gastrectomy plus antrojejunostomy, in order to reproduce a Roux-en-Y gastric bypass (RYGB) mechanistic principles, in patients with previous Sleeve Gastrectomy (SG) who had had weight regain, with or without concomitant gastroesophageal reflux disease (GERD). Background: Sleeve gastrectomy (SG) is one of the most frequently performed bariatric operations worldwide. Nevertheless, weight regain and gastroesophageal reflux disease (GERD) have been consistently demonstrated, in association with this technique, which may require a revisional procedure. RYGB is an option in such a situation but, implies in gastrointestinal exclusions, which represents a shortcoming of this revision. Surpassing this inconvenient would be of great value for the patients. Methods: We describe herein two cases of SG revision for weight regain and GERD, with a follow-up of one year. Gastroesophageal reflux disease was evaluated by validated questionnaire, upper endoscopy, seriography, high resolution manometry (HRM) and impedance pHmetry (I-pHmetry), in the pre and postoperative periods. A re-Sleeve Gastrectomy with antrojejunal anastomosis was done in both cases, after informed consents. The Latarjet nerves were transected in one case, due to a bleeding in the left gastric vessels and a truncal vagotomy was required in the other, to appropriately treat an associated hiatal hernia. Results: In the postoperative evaluation it was observed a pyloric spasm in both cases, during seriography and endoscopy, kept until the one-year follow-up. There was unidirectional contrast flow to the gastrointestinal anastomosis, filling the jejunal limb, in radiologic contrast study. No contrast passed through the pylorus. Nonetheless, the duodenum was kept endoscopically accessible. In the one-year evaluation, weight loss was adequate and GERD resolution

关键词： Roux-en-Y Gastric Bypass Sleeve Gastrectomy jejuno Gastric Bypass Vagus Nerve Vagotomy Bariatric Surgery

Pyloric Sympathectomy: A Novel Way to Get Pylorus Relaxation? Report of Two Bariatric Cases

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Surgical Science 2024年第6期15卷 381-395页

作者： Victor Ramos Mussa Dib carlos Augusto Scussel Madalosso Rui Ribeiro Paulo Reis Esselin de melo fernando fornari Victor Dib Institute Manaus Brazil Gastrobese Clinic Passo Fundo Brazil Lusadas Amadora Hospital Lisboa Portugal Paulo Reis Institute Goinia Brazil Alfredo Nasser University Center (UNIfAN) Goinia Brazil faculdade de Medicina Universidade de Passo Fundo Passo Fundo Brazil faculdade de Medicina Universidade Federal da Fronteira do Sul Chapec Brazil

Objective: This case report aimed to demonstrate a possible neuromuscular effect of pyloric sympathectomy on the pylorus motility, leading to its permanent relaxation, observed in two bariatric surgical cases, one primary and the other, revisional. Background: Pyloric sphincter is a physiological barrier to free gastric emptying. In sleeve gastrectomy and in Roux-en-Y gastric bypass revisions, that put the remnant stomach in transit, the pylorus can contribute to generate a high intragastric pressure, which could lead to acute gastric fistulas and/or chronic gastroesophageal reflux disease. The possibility of functionally relaxing the pylorus, promoting intragastric pressure reduction, could represent a protective maneuver against these complications. Methods: We describe herein a surgical maneuver applied in two cases of bariatric surgeries, with the intention of facilitating antrum-duodenal region exposure, in a sleeve gastrectomy and in a Roux-en-Y gastric bypass conversion to SADI-S. for this, a ligation of terminal peripyloric vessels was done, allowing a passage of a tape, which surrounded the pylorus, for its traction. In both cases, 30-day and 1-year endoscopic evaluations were done, to assess esophagitis signs, anastomosis healing and anatomical pouch aspect. A clinical evaluation was also done, to assess gastroesophageal symptoms (validated questionnaire). Results: In the postoperative endoscopic evaluations, no esophagitis were observed in any case and the gastric pouches had normal aspect, with the expected anatomical findings, compatible with the surgeries performed. The anastomosis healed without problems, in the revisional case. Interestingly, in both cases, it was observed a complete pyloric sphincter relaxation, which lasted until 1-year endoscopic evaluation. There were no fistulas, nor esophagitis in any of these cases. Clinically, there were no symptoms of gastroesophageal reflux disease (validated questionnaire). Conclusion: The observation of a

关键词： Roux-en-Y Gastric Bypass Sleeve Gastrectomy Sympathectomy Bariatric Surgery

Sleeve Gastrectomy with Duodenal Transit Bipartition (S-DTB): Preliminary Results and Technical Aspects of Its Metabolic Structure

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Surgical Science 2024年第4期15卷 244-264页

作者： Paulo Reis Esselin de melo Ricardo Zorron Victor Ramos Mussa Dib carlos Augusto Scussel Madalosso Rui Ribeiro Thonya Cruz Braga Paula Volpe carlos Eduardo Domene Paulo Reis Institute Goiania GO Brazil Alfredo Nasser University Center (UNIfAN) Goiania GO Brazil Department of Bariatric and Metabolic Surgery CUF Descobertas Hospital Lisbon Portugal Victor Dib Institute Manaus AM Brazil Gastrobese Clinic Passo Fundo RS Brazil Lusiadas Amadora Hospital Lisbon Portugal Clianest Group Renaissance Hospital Goiania GO Brazil Integrated Center for Advanced Medicine (CIMAMED) Sao Paulo Brazil

Obesity is a significant and escalating health issue both in Brazil and globally, with over 650 million overweight adults worldwide. The treatment of obesity can be performed clinically, endoscopically or surgically;surgical treatment proves to be safe and more effective in terms of weight loss and long-term maintenance. Objective: This study aimed to monitor the progress of weight loss and comorbidity control in patients undergoing sleeve gastrectomy with duodenal bipartition. Methods: This pilot project involved 8 patients divided into 2 arms. In the first arm, patients underwent sleeve gastrectomy with Roux-en-Y duodenoileal transit bipartition (S-RYDITB), while in the second arm, patients underwent sleeve gastrectomy with Roux-en-Y duodenojejunal transit bipartition (S-RYDjTB). Both procedures involved Roux-en-Y reconstruction without duodenal exclusion. In S-RYDITB, the duodenal-ileal anastomosis was performed 300 cm from the ileocecal valve (ICV), creating a 250 cm common channel and a 50 cm alimentary channel. In S-RYDjTB, a biliopancreatic loop was created 200 cm from the angle of Treitz, with a 1 m alimentary channel. Results: five patients underwent the procedures, with one undergoing S-RYDITB and four undergoing S-RYDjTB. No adverse events such as hospitalizations, readmissions, reoperations, fistulas, bleeding, pulmonary embolism, diarrhea, dumping syndrome, or hypoglycemia occurred during the study period. The mean length of hospital stay was 2 days. The average BMI decreased from 37.27 kg/m2 preoperatively to 29.48 kg/m2 after 6 months. The significant percentage of weight loss was 21.22%, with excess weight loss of 63.6%. Ninety-five percent remission of comorbidities, including hypercholesterolemia, hypertriglyceridemia, diabetes, hypertension, steatosis, and pre-diabetes. Two patients underwent sleeve gastrectomy with duodenal bipartition using a single anastomosis. Conclusion: Duodenal switch surgery has gained worldwide recog

关键词： Obesity Bariatric Surgery Metabolic Surgery Duodenal Switch

Mechanical stimulation devices formechanobiology studies:a market,literature,and patents review

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Bio-Design and Manufacturing 2023年第3期6卷 340-371页

作者： f.melo-fonseca O.Carvalho M.Gasik G.Miranda f.S.Silva Center for MicroElectroMechanical Systems University of Minho(CMEMS-UMinho)Campus de Azurém4800-058 GuimarãesPortugal LABBELS–Associate Laboratory BragaGuimarãesPortugal International Iberian Nanotechnology Laboratory(INL) 4715-330 BragaPortugal School of Chemical Engineering Aalto University Foundation00076 EspooFinland Seqvera Ltd. HelsinkiFinland Department of Materials and Ceramic Engineering CICECOAveiro Institute of MaterialsUniversity of Aveiro3810-193 AveiroPortugal

Significant advancements in various research and technological fields have contributed to remarkable findings on the physiological dynamics of the human *** closely mimic the complex physiological environment,research has moved from two-dimensional(2D)culture systems to more sophisticated three-dimensional(3D)dynamic *** bioreactors or microfluidic-based culture models,cells are typically seeded on polymeric substrates or incorporated into 3D constructs which are mechanically stimulated to investigate cell response to mechanical stresses,such as tensile or *** review focuses on the working principles of mechanical stimulation devices currently available on the market or custom-built by research groups or protected by patents and highlights the main features still open to *** are the features which could be focused on to perform,in the future,more reliable and accurate mechanobiology studies.

关键词： Biomaterials Polymers Actuators Mechanical stress Mechanotransduction

Woody plant taxonomic,functional,and phylogenetic diversity decrease along elevational gradients in Andean tropical montane forests:Environmental filtering and arrival of temperate taxa

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Plant Diversity 2024年第4期46卷 491-501页

作者： Guillermo Bañares-de-Dios Manuel j.Macía Gabriel Arellano Íñigo Granzow-de la Cerda julia Vega-álvarez Itziar Arnelas carlos I.Espinosa Norma Salinas Luis Cayuela Departamento de Biología y Geología Física y Química InorgánicaUniversidad Rey Juan CarlosCalle Tulipán s/nMóstolesMadridES-28933Spain Departamento de Biología Área de BotánicaUniversidad Autónoma de MadridCalle Darwin 2MadridES-28049Spain Centro de Investigación en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autónoma de MadridCalle Darwin 2MadridES-28049Spain Ecology and Evolutionary Biology University of MichiganAnn ArborMI 48109USA Oikobit LLC ***AlbuquerqueNM87120USA Real jardín Botánico–CSIC Plaza Murillo 2MadridES-28014Spain Departamento de Biología Animal EcologíaParasitologíaEdafología y Química AgrícolaUniversidad de SalamancaCalle Donantes de Sangre s/nSalamancaES-37007Spain Departamento de Biodiversidad Ecología y EvoluciónUniversidad Complutense de MadridCalle JoséAntonio Nováis 12Ciudad UniversitariaES-28040Spain Departamento de Ciencias Biológicas y Agropecuarias Universidad Técnica Particular de LojaA.P.11-01-608 LojaEcuador Sección Química Pontificia Universidad Católica del PerúA.P.Lima 32LimaPeru ECI School of Geography and EnvironmentUniversity of OxfordOX13QYOxfordshireUnited Kingdom Instituto de Investigación en Cambio Global(IICG-URjC) Universidad Rey Juan CarlosCalle Tulipán s/nMóstolesMadridES-28933Spain

Mountains are paramount for exploring biodiversity patterns due to the mosaic of topographies and climates encompassed over short *** research has traditionally focused on taxonomic diversity when investigating changes along elevational gradients,but other facets should be *** first time,we simultaneously assessed elevational trends in taxonomic,functional,and phylogenetic diversity of woody plants in Andean tropical montane forests and explored their underlying ecological and evolutionary *** investigation covered four transects(traversing ca.2200 m a.s.l.) encompassing 114 plots of 0.1 ha across a broad latitudinal range(ca.10°).Using Hill numbers to quantify abundance-based diversity among 37,869 individuals we observed a consistent decrease in taxonomic,functional,and phylogenetic diversity as elevation increased,although the decrease was less pronounced for higher Hill *** exception was a slight increase in phylogenetic diversity when dominant species were *** decrease in taxonomic and functional diversity might be attributed to an environmental filtering process towards highlands,where the increasingly harsher conditions exclude species and functional ***,the differences in steepness decrease between Hill orders suggest that rare species disproportionately contribute to functional *** phylogenetic diversity the shifting elevational trend between Hill orders indicates a greater than previously considered influence in central Andean highlands of tropical lowlands originated species with strong niche conservatism relative to distantly related temperate *** could be explained by a decreasing presence and abundance of temperate,extratropical taxa towards the central Andes relative to northern or southern Andes,where they are more prevalent.

关键词： Altitudinal gradients Andes Environmentalﬁltering Out of the Tropical Lowlands functional rarity Tropical Niche Conservatism

The potential of starch-chitosan blends with poloxamer for the preparation of microparticles by spray-drying

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Particuology 2024年第6期89卷 1-10页

作者： juan Enrique Barranco-García Carolina Caicedo Enrique javier jiménez-Regalado carlos Espinoza-González Graciela Morales Rocio Yaneli Aguirre-Loredo Abril fonseca-García Tecnológico Nacional de México/Instituto Tecnológico de Oaxaca Departamento de Química y BioquímicaAvenida Ing.Víctor Bravo Ahuja No.125Esquina Calzada Tecnológico68030OaxacaMexico faculty of Engineering Unidad Central del Valle del Cauca(UCEVA)Carrera 17a 48-144763022TuluáColombia Centro de Investigación en Química Aplicada(CIQA) Blvd.Enrique Reyna Hermosillo 14025294SaltilloCoahuilaMexico Investigadoras por México CONAHCYT-CIQA Av.Insurgentes Sur 1562Col.Crédito Constructor03940Alcaldía Benito JuárezCDMXMexico

Using biopolymers as wall materials in spray drying poses challenges,particularly in attaining flowability and thermal stability among their physicochemical *** paper addresses these challenges by preparing microparticles using a blend of starch–chitosan and a poloxamer,commercially named Pluronic®*** aimed to elucidate the effects of varying poloxamer concentrations on the resulting particles through the spray drying *** with a poloxamer concentration of 3%(w/v)demonstrated a notably higher yield,especially when compared to those with 0%and 1%*** with 3%and 5%(w/v)poloxamer displayed a narrower particle size distribution,with the 3%blend showing a superior yield attributed to arrangements of blend components that improve flowability.X-ray diffraction analysis showcased the characteristic peaks of A-type starch form,with shifts suggesting enhanced interactions between *** with increased poloxamer content showed elevated thermal degradation temperatures,with the 3%blend registering a significant rise,opening avenues for encapsulating heat-sensitive *** study primarily focuses on the preparation and basic characterization of *** underscores the potential of blends with optimal poloxamer concentrations in microencapsulation,emphasizing further research to harness their capabilities thoroughly.

关键词： Biopolymer Starch Chitosan Pluronic®f127 Microparticles Spray drying

Metal-modulated epitaxy of Mg-doped Al_(0.80)In_(0.20)N-based layer for application as the electron blocking layer in deep ultraviolet light-emitting diodes

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journal of Semiconductors 2024年第5期45卷 80-89页

作者： Horacio Irán Solís-Cisneros carlos Alberto Hernández-Gutiérrez Enrique Campos-González Máximo López-López Optomechatronics Group Tecnológico Nacional de México Campus Tuxtla Gutiérrezcarretera Panamericana 1080C.P.29050Tuxtla GutiérrezChiapasMéxico Departamento de física Instituto Nacional de Investigaciones NuclearesCarretera México-Toluca s/nC.P.52750La Marquesa OcoyoacacMéxico Departamento de física Centro de Investigación y estudios Avanzados del Instituto Politécnico NacionalAv.Instituto Politécnico Nacional 2508San Pedro ZacatencoGustavo A.Madero07360 Ciudad de MéxicoCDMXMéxico

This work reports the growth and characterization of p-AlInN layers doped with Mg by plasma-assisted molecular beam epitaxy(PAMBE).AlInN was grown with an Al molar fraction of 0.80 by metal-modulated epitaxy(MME)with a thickness of 180 nm on Si(111)substrates using AlN as buffer *** substrate temperatures were used to enhance the incorporation of indium atoms into the alloy without clustering,as confirmed by X-ray diffraction(XRD).Cathodoluminescence measurements revealed ultraviolet(UV)range ***,Hall effect measurements indicated a maximum hole mobility of 146 cm^(2)/(V∙s),corresponding to a free hole concentration of 1.23×10^(19)cm^(−3).The samples were analyzed by X-ray photoelectron spectroscopy(XPS)estimating the alloy composition and extracting the fermi level by valence band ***-doped AlInN layers were studied for use as the electron-blocking layer(EBL)in LED *** varied the Al composition in the EBL from 0.84 to 0.96 molar fraction to assess its theoretical effects on electroluminescence,carrier concentration,and electric field,using SILVACO *** results from this study highlight the importance and capability of producing high-quality Mg-doped p-AlInN layers through *** simulations suggest that an Al content of 0.86 is optimal for achieving desired outcomes in electroluminescence,carrier concentration,and electric field.

关键词： metal-modulated epitaxy AlInN DUV-LED EBL simulation

The assessment of climatic, environmental, and socioeconomic aspects of the Brazilian Cerrado

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Ecological Processes 2023年第2期12卷 59-70页

作者： Washington Luiz félix Correia filho josé francisco de Oliveira-júnior Dimas de Barros Santiago Hazem Ghassan Abdo Hussein Almohamad Ahmed Abdullah Al Dughairi carlos Antonio da Silva junior Postgraduate Program in Environmentrics(PPGAmb) Institute of Mathematics Statistics and Physics(IMEF) Federal University of Rio Grande(FURG) Institute of Atmospheric Sciences(ICAT) Federal University of Alagoas(UFAL) Postgraduate Program in Biosystems Engineering(PGEB) Federal Fluminense University(UFF) Postgraduate Program in Meteorology Unidade Acadêmica de Ciências Atmosféricas(UACA) Federal University of Campina Grande(UFCG) Geography Department Faculty of Arts and Humanities Tartous University Geography Department Faculty of Arts and Humanities Damascus University Geography Department Faculty of Arts and Humanities Tishreen University Department of Geography College of Arabic Language and Social Studies Qassim University Departamento de Geografia State University of Mato Grosso(UNEMAT)

Background The Cerrado is the most biodiverse savanna and maintains other biomes. Aware of its significance, this paper evaluated the Brazilian Cerrado's climatic, environmental, and socioeconomic aspects using remote sensing data and spatial statistics(correlation analysis and principal components analysis—PCA). following the measures of sample adequacy(MSA) and Kaiser–Meyer–Olkin(KMO) tests, seventeen variables were *** The MSA revealed that the dataset had a good quality(0.76), and nine variables were selected: elevation, evapotranspiration, active fires, Human Development Index(HDI), land use and land cover(LULC; shrubland and cropland/rainfed), rainfall(spring and autumn), and livestock. The correlation matrix indicated a positive(negative) association between HDI and autumn rainfall(HDI and active fires) with a value of 0.77(-0.55). The PCA results determined which three principal components(PC) were adequate for extracting spatial patterns, accounting for 68.02% of the total variance with respective values of 38.59%, 16.89%, and 12.5%. Due to economic development and agribusiness, Cerrado's northern(central, western, and southern) areas had negative(positive) score HDI values, as shown in PC1. Climatic(rainfall—spring and fall) and environmental(cropland/rainfed and shrubland) aspects dominated the PC2, with negative scores in northern and western portions due to the transition zone between Amazon and Cerrado biomes caused by rainfall variability. On the other hand, environmental aspects(LULC-shrubland and elevation) influenced the PC3; areas with high altitudes(> 500 m) received a higher *** Agricultural expansion substantially affected LULC, leading to deforestation-caused suppression of native vegetation.

关键词： Environment Agribusiness Active fire Human Development Index Land use and land cover

Retention of eucalyptus harvest residues reduces soil compaction caused by deep subsoiling

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journal of forestry Research 2022年第2期33卷 643-651页

作者： Raphael Oliveira de melo AymbiréAngeletti da fonseca Nairam félix de Barros Raphael Bragança Alves fernandes Rafael da Silva Teixeira Iago Nery melo Ricardo Previdente Martins Soil Science Department Universidade Federal de ViçosaViçosaMinas GeraisBrazil BRACELL Company AlagoinhasBahiaBrazil

Eucalyptus harvesting,forwarding and soil tillage operations are among the main causes for compaction of forest soils,with potential impacts on *** concern is especially important in areas with soils that are naturally compacted(fragipans and duripans).In these soils,tillage operations include the use of subsoilers that can reach depths of more than one meter and require heavy tractors that exert high pressure on the *** of the ways to try to minimize the effect of this compaction is by retaining harvest *** objective of this study was to evaluate the impacts of eucalyptus harvesting on soil physical attributes,as well as to determine the potential of different types of residue management to reduce compaction from the soil tillage *** experiments were conducted in the same area with a Yellow *** the first experiment,compaction caused by mechanized harvesting with harvester+forwarder was *** the second experiment,different managements of harvest residues were examined as potential modifiers of soil compaction during tillage for new *** this,three managements systems were tested:(1)retention of all harvest residues and litter from the previous rotation(HR+L),(2)retention of litter from the previous rotation(L),and(3)removal of harvest residues and litter from the previous rotation(WR).Before and after harvest,sampling was carried out in the planting rows and inter-rows,and after tillage,samples were collected in the traffic line of the subsoiler-tractor *** both experiments,undisturbed soil samples were collected from the center of the 0-10,10-20,20-40,40-60,and 60-100 cm layers to determine soil density and total *** each period and site of evaluation,mechanical resistance to penetration up to the 60-cm depth was also *** harvesting operation increased soil density at 0-10 and 60-100 cm depths only in the *** of harvest residues and litter(HR+L)after harvesting avoi

关键词： Soil penetration resistance Harvester+forwarder Soil tillage Soil density Cohesive soils