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Analysis of the Risks of Development Injury Related to Surgical Positioning in a University Hospital of the State of Goiás/Brazil: An Observational-Epidemiological Study

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Health 2020年第7期12卷 876-890页

作者： Bárbara Almeida Lemes Barbara Correia Neves sabino carlos eduardo carvalho sabino Ana Clara Lenza Martins Ana Letícia Neller Finta André Vinícius de Oliveira Mariana Cordeiro carvalho Carolina Veras Mendes Giulia Ugucioni Garbelini Lara Cândida de Sousa Machado Idiberto José Zotarelli Filho Rio Verde University—UniRv Rio Verde Goiás Brazil Faculty of Medical Sciences State University of Campinas—UNICAMP Campinas Brazil Southwest Emergency Hospital—HURSO Brazil Faceres Medical School of Sã o José do Rio Preto/SP Brazil

Introduction: The perioperative nurse plays an important role throughout the surgical period, especially in the context of predicting the risks to which patients are exposed when entering a surgical center. These can be skin, muscle, tendon, and even burn injuries from the scalpel or chemicals. Objective: The aim of this study was to verify the degree of risk for the development of injuries resulting from surgical positioning in patients of a university hospital. Methods: This is cross-sectional, exploratory research with a quantitative approach conducted with 70 surgical patients in a Municipal University Hospital with data collection through a socioeconomic and health questionnaire and the Risk Assessment Scale for Development of Surgical Positioning Injuries (SISP). Statistical analyses included simple descriptive evaluation, correlations of variables using the Chi-square test and Pearson’s coefficient with a significance level of 5%. Results: The results found pointed to a population mainly composed of women (60%), married, with an average age of 49 years, with hypertension and high-risk scores to develop injuries due to surgical positioning. There was also a positive and significant correlation between having hypertension and having a higher risk of developing lesions, with R2 = 96.4% and p Conclusion: The results reinforce the need to implement protocols and the acquisition of materials aimed at reducing the risk of injuries related to surgical positioning in order to improve the quality of care offered and thus minimize the harm to users.

关键词： Nursing Pressure Injury Operating Room

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How far have we come?Review of main public policies to reduce landslide impacts in Brazil

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Journal of Mountain Science 2024年第9期21卷 2891-2904页

作者： Bianca carvalho VIEIRA Tiago Damas MARTINS Telma Mendes da SILVA Joséeduardo BONINI Department of Geography University of São PauloAvenida Professor Lineu Prestes 05508-000Brazil Cities Institute Federal University of São PauloAvenida Jacu-Pêssego 08260-001Brazil Department of Geography Federal University of Rio de JaneiroAvenida Athos da Silveira Ramos 21941-916Brazil

During the rainy season in Brazil,landslides can have catastrophic consequences,including loss of life,damage to urban infrastructure and significant economic ***,more than eight million people in Brazil live in disaster-prone *** objective of this article is to present a chronological review of the principal policies and programmes at the national,state,and municipal levels,with an emphasis on their key actions aimed at mitigating the impact of disasters related to natural hazards,particularly *** analysis was based on official records of public policies from the national,state,and municipal *** results show that several initiatives were initially developed at the local and regional ***,it was not until the late 1980s that a comprehensive organisation of civil protection at the national level emerged as a response *** is possible to highlight three phases(understanding,coexistence,and prevention)of institutional action focused on risk management in the face of *** the growing knowledge of risk scenarios,disasters continue to occur in Brazil on an annual basis,revealing several obstacles to reducing their impact,particularly given the social and economic disparities between Brazilian regions and the applicability of public policies that must overcome the limitations of each municipality.

关键词： Disasters Risk Mitigation Prevention Legislation Civil Defense Natural Hazards

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Thermal and salinity effects on locomotor performance of Thoropa taophora tadpoles(Anura,Cycloramphidae)

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Integrative Zoology 2020年第1期15卷 40-54页

作者： Antonio C.GALLO Cinthia ABRASILEIRO Fábio Cury DE BARROS Joséeduardo DE carvalho Department of Ecology and Evolutionary Biology Federal University of São PauloDiademaSão PauloBrazil

It is well known that environmental temperature influences several biological functions of ectotherms,notably in *** high permeability of anuran skin,associated with the effect of elevated environmental temperature,potentiates the dehydration process and this combination may restrict locomotor ***pa taophora is an endemic species from the Atlantic Rainforest whose tadpoles are semiterrestrial and predominantly diurnal,and are found in rocky seashores where they are exposed to sea spray and high *** this study we investigated how temperature and salinity conditions affect the locomotor performance in Thoropa taophora *** also assessed how different osmotic concentrations affect the activity of the metabolic pathways that support muscle *** measured the sprint speed of tadpoles of various sizes at different temperatures and salinities in the *** also measured the activity of the enzymes pyruvate kinase(PK),lactate dehydrogenase(LDH)and citrate synthase(CS)in different temperatures and osmotic concentrations,and calculated the thermal sensitivity and the activity constants for each *** results showed that,in general,sprint speed decreased with increasing temperature and ***,whereas the effect of increased salinity was similar in smaller and larger tadpoles,increased temperature had a higher negative impact on sprint speed of larger tadpoles,thus indicating low thermal sensitivity of small *** and LDH thermal sensitivities and LDH constant of activity decreased as the osmolality *** conclusion,the locomotor capacity of tadpoles was decreased by temperature and salinity,which may be related to a decrease in anaerobic metabolism both in terms of sensitivity and total energy turnover through enzymatic *** discuss the ecological consequences,including the potential impacts on predator escape behavior promoted by changes in metabolism and locomotor performance

关键词： amphibians energy metabolism enzyme activity sprint speed

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Foliar application of rare earth elements on soybean(Glycine max(L)):Effects on biometrics and characterization of phytotoxicity

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Journal of Rare Earths 2020年第10期38卷 1131-1139,I0005页

作者： eduardo S.Rodrigues Gabriel S.Montanha Joao P.R.Marques eduardo de Almeida Lauren N.M.Yabuki Amauri A.Menegario Hudson W.Pereira de carvalho Laboratory of Nuclear Instrumentation(LIN) Center for Nuclear Energy in Agriculture(CENA)University of Sao Paulo(USP)PiracicabaSP13416-000Brazil Environmental Studies Center Sao Paulo State University(UNESP)Rio ClaroSP13506-900Brazil

This study aims at investigating the effects of foliar application of aqueous solutions of La3+and Ce3+nitrates on soybean plants(Glycine max).First,we observe that Triton HW 1000 surfactant at 0.01 vol%reduces droplets contact angle and increases their drying *** greenhouse conditions,the foliar treatments do not affect chlorophyll content,plant height,number of leaves,number of pods,number of seeds per pod,and average seed ***,the treatments induce phytotoxicity since foliar injuries appear after the *** X-ray fluorescence spectroscopy combined to scanning electron microscopy shows that the leaf lesions are positively correlated to accumulation of Ce and La on the leaf surface and also promote structural alteration to the epidermal cells.X-ray absorption near edge structure shows that the La and Ce nitrates are partially bio transformed into oxides by the leaves which might explain the harmful effects.

关键词： Leaf fertilization Rare earth elements Soybean X-ray fluorescence spectroscopy X-ray absorption spectroscopy

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Management of hepatitis C in patients with chronic kidney disease

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World Journal of Gastroenterology 2015年第2期21卷 408-422页

作者： Roberto J carvalho-Filho Ana Cristina CA Feldner Antonio eduardo B Silva Maria Lucia G Ferraz Division of Gastroenterology Hepatology SectionFederal University of Sao PauloSao PauloSP 04023-900Brazil

Hepatitis C virus(HCV) infection is highly prevalent among chronic kidney disease(CKD) subjects under hemodialysis and in kidney transplantation(KT) recipients, being an important cause of morbidity and mortality in these patients. The vast majority of HCV chronic infections in the hemodialysis setting are currently attributable to nosocomial transmission. Acute and chronic hepatitis C exhibits distinct clinical and laboratorial features, which can impact on managementand treatment decisions. In hemodialysis subjects, acute infections are usually asymptomatic and anicteric; since spontaneous viral clearance is very uncommon in this context, acute infections should be treated as soon as possible. In KT recipients, the occurrence of acute hepatitis C can have a more severe course, with a rapid progression of liver fibrosis. In these patients, it is recommended to use pegylated interferon(PEG-IFN) in combination with ribavirin, with doses adjusted according to estimated glomerular filtration rate. There is no evidence suggesting that chronic hepatitis C exhibits a more aggressive course in CKD subjects under conservative management. In these subjects, indication of treatment with PEG-IFN plus ribavirin relies on the CKD stage, rate of progression of renal dysfunction and the possibility of a preemptive transplant. HCV infection has been associated with both liver disease-related deaths and cardiovascular mortality in hemodialysis patients. Among those individuals, low HCV viral loads and the phenomenon of intermittent HCV viremia are often observed, and sequential HCV RNA monitoring is needed. Despite the poor tolerability and suboptimal efficacy of antiviral therapy in CKD patients, many patients can achieve sustained virological response, which improve patient and graft outcomes. Hepatitis C eradication before KT theoretically improves survival and reduces the occurrence of chronic graft nephropathy, de novo glomerulonephritis and post-transplant diabetes mellitus.

关键词： Hepatitis C virus Chronic kidney disease End-stage

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Potential of four marine-derived fungi extracts as anti-proliferative and cell death-inducing agents in seven human cancer cell lines

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Asian Pacific Journal of Tropical Medicine 2015年第10期8卷 782-790页

作者： Alice Abreu Ramos Maria Prata-Sena Bruno Castro-carvalho Tida Dethoup Suradet Buttachon Anake Kijjoa eduardo Rocha Interdisciplinary Center for Marine and Environmental Research(CIIMAR) CIMAR Associate Laboratory(CIMAR LA)University of Porto(U.Porto) ICBAS-Institute of Biomedical Sciences Abel Salazar University of Porto(U.Porto) Department of Plant Pathology Faculty of AgricultureKasetsart University

Objective:To evaluate the in vitro anticancer activity of crude ethyl acetate extracts of the culture of four marine-derived fungi Aspergillus similanensis KUFA 0013(E1),Neosartorya paulistemis KUFC 7897(E2),Neosartorya siamensis KUFA 0017(E4) and Talaromyces trachyspermus KUFC 0021(E3) on a panel of seven human cancer cell ***:Effects on cell proliferation,induction of DNA damage and cell death were assessed by MTT and clonogenic assays,comet assay and nuclear condensation assay,***:The proliferation of HepG2,HCTl 16 and A375 cells decreased after incubation with the extracts E2 and *** anti-proliterative effect was confirmed by morphologic alterations and by clonogenic *** extracts also induced cell death in HepG2 and HCT116 *** was used as a positive control and showed in vitro anticancer ***:This study demonstrated,for the first time,that extracts of Neosartorya paulistensis and Neosartorya siamensis have selective anti-proliferative and cell death activities in HepG2,HCT16 and A375 *** bioactivity of these extracts suggests a potential for biotechnological applications and substantiates that both should be further considered for the elucidation of the molecular targets and signal transduction pathways involved.

关键词： Anti-proliferative activity Antineoplastic agents

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Genetic Parameters Estimates Associated to Conversion of Nicotine to Nornicotine in Burley Tobacco

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American Journal of Plant Sciences 2014年第21期5卷 3380-3388页

作者： Bruna Line carvalho Magno Antonio Patto Ramalho carlos eduardo Pulcinelli Adriano Teodoro Bruzi Department of Biology Genetics and Breeding of Plants Program Universidade Federal de Lavras Lavras Brazil Souza Cruz SA Rio Negro Brazil Department of Agriculture Universidade Federal de Lavras Lavras Brazil

Nicotine represents the predominant alkaloid in cultivated tobacco. In burley varieties, during senescence and curing of leaves, nicotine can be converted to nornicotine, which is highly undesirable because of its relationship with the tobacco specific nitrosamines formation. Thus, an alternative for producing varieties with low or null nornicotine content would be to select plants or progenies for traits related to nicotine conversion. Therefore, understanding genetic control and inheritance underlying this process is important to chooseappropriate strategies in breeding programs. Two contrasting inbred lines for nicotine conversion to nornicotine, TN 90 and BY 37, have been crossed to obtain the segregating generations (F2 and BCs). Genetic parameters of mean and variance, as well as the average degree of dominance and heritability were estimated. It has been found that nicotine conversion has predominantly additive effects, and in addition, narrow sense heritabilities at the individual level were higher than 65%. Both are desirable conditions for conducting a selection program of burley tobacco aiming at development of inbred lines associating yield and other traits with low or null nicotine conversion.

关键词： Quantitative Genetics Plant Breeding Nicotianatabacum L. Genetic Control Inheritance

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Old climatically-buffered infertile landscapes(OCBILs):more than harsh habitats,Atlantic Forest inselbergs can be drivers of evolutionary diversity

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Journal of Mountain Science 2022年第9期19卷 2528-2543页

作者： Felipe de carvalho ARAÚJO Natália de AGUIAR-CAMPOS Cleber Rodrigo de SOUZA eduardo de Paiva PAULA Rubens Manoel dos SANTOS Laboratory of Phytogeography and Evolutionary Ecology Department of Forest SciencesFederal University of LavrasLavrasMinas GeraisBrazil

Granite-gneiss rock outcrop inselbergs are ancient stable ecosystems with old,climaticallybuffered infertile landscapes(OCBILs).Although inselbergs provide key ecosystem services,little is done for their conservation and,so far,a lot of their unknown evolutionary history has already been lost by human *** a fine-scale approach,here we tested if habitat and environmental filtering(the inselberg’s harshness)affect the evolutionary diversity of an Atlantic Forest inselberg in *** recorded all trees with a diameter at breast height≥5cm in 20 plots in four habitat types(total sampled area of 0.8 hectares),from highest to lowest:island,hillside,foothill,and semideciduous forest(matrix).We also collected soil samples for chemical,textural and physical soil *** fitted linear models to test the effects of soil and habitat on plotlevel metrics of phylogenetic diversity and structure,lineage diversity,phylogeneticβ-diversity,and evolutionary *** found that the upper inselberg habitats contain a distinct set of ancient,closely related,harsh-tolerant lineages,as well as a subset of lineages that persist under harsh conditions with a certain degree of water *** inferior inselberg habitats harbor higher lineage diversity than expected by *** strongly predicted evolutionary *** concluded that soil depth,slope,nutrients and texture(environmental filtering)and habitat types and topography(habitat filtering)shape the evolutionary history contained in fine-scale inselberg habitats,which should encourage the conservation of these ancient ecosystems.

关键词： Phylogenetic diversity Atlantic Forest Niche conservatism Environmental filters Soil fertility Terrestrial Island

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Glutamine and glutamate supplementation raise milk glutamine concentrations in lactating gilts

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Journal of Animal Science and Biotechnology 2012年第1期3卷 25-31页

作者： Helena Emilia CCC Manso Helio C Manso Filho Luiz E de carvalho Marianne Kutschenko eduardo T Nogueira Malcolm Watford Department of Animal Sciences Rural Federal University of PernambucoRecifePE52171-900Brazil Departament of Animal Sciences Federal University of CearáFortalezaCE60020-181Brazil Ajinomoto do Brazil S oPauloSP04015-001Brazil Department of Nutritional Sciences Rutgers UniversityNew BrunswickNJ08901USA.

Glutamine is the most abundant amino acid in milk, and lactation is associated with increased glutamine utilization both for milk synthesis and as a fuel for the enlarged small intestine. A number of recent studies have indicated that lactation is accompanied by a mild catabolic state in which skeletal muscle proteins are degraded to provide amino acids that are used to synthesize additional glutamine. In this study we tested the hypothesis that supplemental L-glutamine or the commercially available glutamine supplement Aminogut （2.5% by weight mixed into daily feed） provided to gilts from 30 days prior to parturition until 21 days post-parturition would prevent a decrease in skeletal muscle glutamine while increasing the glutamine content of the milk. Muscle glutamine content decreased （P 〈 0.05） in control animals during lactation but this was prevented by supplementation with either L-glutamine or Aminogut. In this study, neither lactation nor supplementation had any effect on plasma glutamine or glutamate content. Free glutamine, and the total glutamine plus glutamate concentrations in milk from the control and the Aminogut group rose （P 〈 0.05） during the first 7 days of lactation, with milk concentrations in the L-glutamine supplemented group showing a similar trend （P = 0.053）. Milk glutamate remained constant between day 7 and 21 of lactation in the control and L-glutamine supplemented groups, but by day 21 of lactation the free glutamine, glutamate, and glutamine plus glutamate concentrations in milk from Aminogut-treated gilts were higher than those of control gilts. Thus dietary glutamine supplementation can alleviate the fall in intramuscular glutamine content during lactation in gilts, and may alleviate some of the catabolic effects of lactation. Furthermore, the increased milk glutamine content in the supplemented gilts may provide optimum nutrition for piglet development.

关键词： glutamate glutamine lactation milk pig skeletal muscle

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Cerium alleviates drought-induced stress in Phaseolus vulgaris

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Journal of Rare Earths 2020年第3期38卷 324-331页

作者： Olívia Graziela Gelioli Salgado Jéssica Cristina Teodoro Joyce Pereira Alvarenga Cynthia de Oliveira Teotonio Soares de carvalho Débora Domiciano Paulo eduardo Ribeiro Marchiori Luiz Roberto Guimaraes Guilherme Department of Soil Science Federal University of LavrasCP 3037Campus UFLALavras37200-000Brazil Department of Biology Federal University of LavrasCP 3037Campus UFLALavras37200-000Brazil

Extreme drought events are expected to be one of the main challenges for tropical agriculture and,consequently,for global food *** this reason,it is urgent to develop strategies to increase water use efficiency,as well as to increase crops’ ability to cope with *** rare earth elements(REEs) are known to alleviate damages in plants under abiotic stresses,we hypothesized that addition of Ce^3+to nutrient solution would promote the growth of common bean,especially under simulated drought *** test this hypothesis,we conducted an experiment evaluating the effect of six Ce^3+concentrations on the development and physiological traits of common bean grown in nutrient solution under normal condition and under induced drought stress,caused by the addition of polyethylene glycol6000 to the nutrient *** results show that Ce^3+alleviates water stress in common bean plants,increasing their survival rate and *** addition,Ce^3+application increases photosynthesis rate,chlorophyll content and water use efficiency under water ***,we observe no significant effect of Ce^3+on plants growing under normal ***,Ce3+seems to be a promising attenuator of drought stress for common bean.

关键词： Water stress Polyethylene glycol Rare earth elements Cerium nitrate Mitigation Common bean

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