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Nonlinear numerical assessment of the seismic response of hillside RC buildings

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Earthquake Engineering and Engineering Vibration 2021年第2期20卷 423-440页

作者： Miguel a.g.mez Edgar giovanny Díaz-Segura Juan carlos Vielma Civil Engineering School Pontificia Universidad Católica de ValparaísoValparaíso 2340000Chile

Major damage has been reported in hilly areas after major earthquakes,primarily because of two special conditions:the variation in the seismic ground motion due to the inclined ground surface and the irregularities caused by a stepped base level in the *** aim of this study is to evaluate possible differences in the responses of Chilean hillside buildings through numerical linear-elastic and nonlinear *** the first step,a set of response-spectrum analyses were performed on four simplified 2D structures with mean base inclination angles of 0°,15°,30°,and 45°.The structures were designed to comply with Chilean seismic codes and standards,and the primary response parameters were *** assess the seismic performance of the buildings,nonlinear static(pushover)and dynamic(time-history)analyses were performed with SeismoStruct *** analyses were used to compare the nonlinear response at the maximum roof displacement and the damage ***-history analyses were performed to assess the nonlinear dynamic response of the structures subjected to seismic ground motions modified by topographic *** consider the topographic modification,acceleration records were obtained from numerical models of soil,which were calculated using the rock acceleration record of the Mw 8.01985 Chilean *** differences in the structure responses(roof displacements and maximum element forces and moments)were caused by the topographic effects in the seismic input motion,with the highly predominant ones being the differences caused by the step-back configuration at the base of the *** concentrations of shear forces in short walls were observed,corresponding to the walls located in the upper zone of the foundation *** response of the structures with higher angles was observed to be more prone to fragile failures due to the accumulation of shear *** though hillside buildings gain stiffness in the lower stories,resulting

关键词： topographic effect hillside buildings nonlinear analyses shear-wall buildings

Differentiated payments for environmental services schemes: A methodology proposal

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Journal of Mountain Science 2018年第8期15卷 1693-1710页

作者： carlos R.AgUILAR-gómez Sergio FRANCO-MAASS Tizbe T.ARTEAgA-REYES Agrolivestock Sciences and Rural Institute Autonomous University of the State of Mexico

Payment schemes for environmental services face serious budget constraints in Mexico. Payments are equally distributed among forest owners, and the governmental agencies that make payments to beneficiaries do not evaluate the amount of environmental services produced by forested areas. This lack of evaluation could lead to economic and environmental deficiencies that restrict the possible benefits of such programmes. In general, these programmes do not achieve their conservation objectives, and local beneficiaries are not involved in the design or application of these programmes. Similarly, the Payments for Hydrological Environmental Services(PHES) programme of the State of Mexico, Mexico, makes equal payments to beneficiaries of forested areas considering tree density. The objective of the present work was to create a methodology for determining differentiated payments schemes for hydrological environmental services, prioritising areas that contribute the most to groundwater recharge and promote the participation of society. In the Nevado de Toluca Natural Protected Area, the environmental criteria of forest type, tree density and aquifer overexploitation as well as social participation were considered in a multi-criteria analysis implemented in a geographic Information System. A methodology was developed to determine differentiated payments based on specific forest characteristics that influence the potential capacity of forests to recharge groundwater reserves in addition to the level of social participation. In particular, social participation is key as it could ensure the viability of PHES programmes as conservation alternatives in forested areas with high groundwater recharge potential.

关键词： Differentiated payments Environmental services Mountain systems Multi-criteria analysis Social participation

Physical exercises for preventing injuries among adult male football players:A systematic review

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Journal of Sport and Health Science 2022年第1期11卷 115-122页

作者： Jorge Pérez-gómez JoséCarmelo Adsuar Pedro EAlcaraz Jorge carlos-Vivas Health EconomyMotricity and Education(HEME)Research GroupFaculty of Sports SciencesUniversity of ExtremaduraCaceres 10003Spain UCAM Research Center for High Performance Sport Catholic University of MurciaMurcia 30107Spain Faculty of Sport Sciences Catholic University of MurciaMurcia 30107Spain

Background:Football is the most practised sport in the world and is associated with the risk of injuries in the *** studies have been published that identify injury prevention programs,but there is no review of the full body of evidence on injury prevention programs for use by football *** aim of this article was to carry out a systematic review of published studies on injury prevention programs for adult male footballers,identify points of common understanding and establish recommendations that should be considered in the design of injury prevention ***:PubMed and EMBASE databases were used to identify relevant published articles using the following keywords:"soccer"AND"injury"AND"prevention".Results:A total of 2512 studies were identified initially,but only 11 studies met the inclusion criteria,and their outcomes are *** revealed that injury prevention programs in football have focused on strength training,proprioceptive training,multicomponent programs(balance,core stability,and functional strength and mobility),and warm-up ***:Based on results from the studies analyzed,football players can lower the incidence of match and training injuries by participating in dynamic warm-up programs that include preventive exercises before games or during training sessions,and by adding strength,balance,and mobility training to the training sessions.

关键词： Balance Core stability Injury prevention programs Soccer Warm-up

Predicting intensive care unit-acquired weakness:A multilayer perceptron neural network approach

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World Journal of Clinical Cases 2024年第12期12卷 2023-2030页

作者： carlos Martin Ardila Daniel gonzález-Arroyave Mateo Zuluaga.g.mez Department of Basic Sciences University of AntioquiaMedellín 52-59Colombia Department of Surgery Pontificia Universidad BolivarianaMedellín 0057Colombia Department of Emergency Universidad Pontificia BolivarianaMedellín 0057Colombia

In this editorial,we comment on the article by Wang and Long,published in a recent issue of the World Journal of Clinical *** article addresses the challenge of predicting intensive care unit-acquired weakness(ICUAW),a neuromuscular disorder affecting critically ill patients,by employing a novel processing strategy based on repeated machine *** editorial presents a dataset comprising clinical,demographic,and laboratory variables from intensive care unit(ICU)patients and employs a multilayer perceptron neural network model to predict *** authors also performed a feature importance analysis to identify the most relevant risk factors for *** editorial contributes to the growing body of literature on predictive modeling in critical care,offering insights into the potential of machine learning approaches to improve patient outcomes and guide clinical decision-making in the ICU setting.

关键词： Intensive care units Intensive care unit-acquired weakness Risk factors Machine learning Computer neural network

Impact of aspiration catheter size on first-pass effect in the combined use of contact aspiration and stent retriever technique

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Stroke & Vascular Neurology 2021年第4期6卷 553-560页

作者： carlos Pérez-garcía Christian Maegerlein Santiago Rosati Charlotte Rüther carlos gómez-Escalonilla Claus Zimmer Juan Arrazola Maria Teresa Berndt Manuel Moreu Interventional Neuroradiology Hospital Clinico Universitario San CarlosMadridSpain Department of Diagnostic and Interventional Neuroradiology Klinikum rechts der Isar der Technischen Universitat MunchenMunchenBayernGermany Neurology Hospital Clinico Universitario San CarlosMadridSpain Radiology Hospital Clinico Universitario San CarlosMadridSpain

Background and purpose The first-pass effect(FPE),defined as a first-pass Expanded Treatment in Cerebral Ischaemia(eTICI)2c/3 reperfusion,has emerged as a key metric of efficacy in mechanical thrombectomy(MT)for acute ischaemic *** proximal balloon occlusion together with direct thrombus aspiration during stent retriever thrombectomy(PROTECT)-PLUS technique consists in the use of a balloon guide catheter and a combined MT approach involving contact aspiration and a stent *** aim of this study is to assess the effectiveness and safety of the PROTECT-PLUS technique using distal aspiration catheters(DACs)with different inner diameters by comparing the large-bore DAC Catalyst 7 versus the use of medium-bore *** Retrospective analysis of a prospectively maintained database of patients treated with PROTECT-PLUS using Catalyst 7,Catalyst 6 or Catalyst 5 with an occlusion of either the terminal carotid artery or the M1 or M2 segments of the middle cerebral artery from 2018 to 2020 in two comprehensive stroke *** characteristics and procedural,safety and clinical outcomes were compared between *** logistic regression analysis was performed in order to find independent predictors of *** We identified 238 consecutive patients treated with PROTECT-PLUS as front-line approach using Catalyst 7(n=86),Catalyst 6(n=78)and Catalyst 5(n=76).The rate of FPE was higher with Catalyst 7(54%)than Catalyst 6(33%,p=0.009)and Catalyst 5(32%,p=0.005),in addition to higher final eTICI 2c/3 reperfusion rates,shorter procedural times,lower need of rescue therapy and fewer procedure-related *** multivariable analysis the sole independent factor associated to FPE was the use of Catalyst 7(OR 2.34;95%CI 1.19 to 4.58;p=0.014).Conclusion Further development of combined MT by incorporating larger-bore aspiration catheters is associated with higher reperfusion rates,shorter procedure times,and lower need of rescue therapy wh

关键词： shorter effect maintained

Synthesis of advanced ceramics by hydrothermal crystallization and modified related methods

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Journal of Advanced Ceramics 2012年第3期1卷 204-220页

作者： JoséORTIZ-LANDEROS carlos gÓmez-YÁÑEZ Rigoberto LÓPEZ-JUÁREZ Iván DÁVALOS-VELASCO Heriberto PFEIFFER Departamento de Ingeniería Metalúrgica Escuela Superior de Ingeniería Química e Industrias ExtractivasIPNUPALMAv.Instituto Politécnico Nacional s/nCP 07738México DFMéxico. Centro de Ciencias Aplicadas y Desarrollo Tecnológico Universidad Nacional Autónoma de MéxicoA.P.70-186CoyoacánMéxico D.F.México. Instituto de Investigaciones en Materiales Universidad Nacional Autónoma de MéxicoCircuito exterior s/nCiudad UniversitariaDel.CoyoacánCP 04510México DFMéxico.

The present article aims to give a brief overview about the advantages of the hydrothermal crystallization method for the synthesis of advanced *** is given,not only on the conventional hydrothermal crystallization,but also on some of its variants;such as ultrasound-assisted,electrochemical-assisted,microwave-assisted and surfactant-assisted hydrothermal methods which open up new opportunities for the synthesis of ceramic materials with novel properties demanded for advanced *** the current work the synthesis of barium titanate(BaTiO3),lithium metasilicate(Li2SiO3)and sodium-potassium niobate(Na,K)NbO3 powders are reported as cases of study.

关键词： hydrothermal synthesis barium titanate Li_(2)SiO_(3) potassium-sodium niobate

Steatosis and insulin resistance in hepatitis C: A way out for the virus?

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World Journal of gastroenterology 2009年第40期15卷 5014-5019页

作者： José A Del Campo Manuel Romero-gómez Unit for The Clinical Management of Digestive Diseases and CIBERehd Hospital Universitario de Valme

The hepatitis C virus (HCV) induces lipid accumulation in vitro and in vivo. The pathogenesis of steatosis is due to both viral and host factors. Viral steatosis is mostly reported in patients with genotype 3a, whereas meta-bolic steatosis is often associated with genotype 1 and metabolic syndrome. Several molecular mechanisms responsible for steatosis have been associated with the HCV core protein, which is able to induce gene expres-sion and activity of sterol regulatory element binding protein 1 (SREBP1) and peroxisome proliferator-activat-ed receptor γ (PPARγ), increasing the transcription of genes involved in hepatic fatty acid synthesis. Steatosis has been also implicated in viral replication. In infected cells, HCV core protein is targeted to lipid droplets which serve as intracellular storage organelles. These studies have shown that lipid droplets are essential for virus assembly. Thus, HCV promotes steatosis as an eff icient mechanism for stable viral replication. Chronic HCV in-fection can also induce insulin resistance. In patients with HCV, insulin resistance is more strongly associated with viral load than visceral obesity. HCV seems to lead to insulin resistance through interference of intracellular insulin signalling by HCV proteins, mainly, the serine phosphorylation of insulin receptor-1 (IRS-1) and im-pairment of the downstream Akt signalling pathway. The HCV core protein interferes with in vitro insulin signal-ling by genotype-specif ic mechanisms, where the role of suppressor of cytokine signal 7 (SOCS-7) in genotype 3aand mammalian target of rapamycin (mTOR) in geno-type 1 in IRS-1 downregulation play key roles. Steatosis and insulin resistance have been associated with f ibrosis progression and a reduced rate of sustained response to peginterferon plus ribavirin.

关键词： Steatosis Insulin resistance Hepatitis Cvirus

Eosinophilic esophagitis: Current concepts in diagnosis and treatment

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World Journal of gastroenterology 2019年第32期25卷 4598-4613页

作者： Andrés gómez-Aldana Mario Jaramillo-Santos Andrés Delgado carlos Jaramillo Adán Lúquez-Mindiola Departament of Internal Medicine Section of GastroenterologySanta Fe Foundation of Bogotá(Fundación Santa Fe de Bogotá)Bogotá220246Colombia University of Los Andes Bogotá111711Colombia Department of Endoscopy Caldas UniversityManizales 275Colombia Department of Endoscopy Surgeons’Union SAS(Joint stock company)(Union de cirujanos SAS)Manizales 170001661Colombia Department of gastroenterology Gut MédicaBogotá110221001Colombia

Eosinophilic esophagitis is an immune-allergic pathology of multifactorial etiology(genetic and environmental)that affects both pediatric and adult *** symptoms,which include heartburn,regurgitation,and esophageal stenosis(with dysphagia being more frequent in eosinophilic esophagitis in young adults and children),are similar to those of gastroesophageal reflux disease,causing delays in diagnosis and *** endoscopic findings such as furrows,esophageal mucosa trachealization,and whitish exudates may suggest its presence,this diagnosis should be confirmed histologically based on the presence of more than 15 eosinophils per high-power field and the exclusion of other causes of eosinophilia(parasitic infections,hypereosinophilic syndrome,inflammatory bowel disease,among others)for which treatment could be ***,the 3“D”s(“Drugs,Diet,and Dilation”)are considered the fundamental components of *** first 2 components,which involve the use of proton pump inhibitors,corticosteroids,immunosuppressants and empirical diets or guided food elimination based on allergy tests,are more useful in the initial phases,whereas endoscopic dilation is reserved for esophageal ***,the most important aspects of eosinophilic esophagitis pathophysiology will be reviewed,in addition to evidence for the various treatments.

关键词： Eosinophilic esophagitis Corticoid Esophageal stenosis Diet Dilation Proton pump inhibitor

“The red cage”:implementation of pH-responsiveness within a macrobicyclic pyridinium-based molecular host

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Organic Chemistry Frontiers 2022年第1期9卷 81-87页

作者： Pablo Cortón Hongye Wang Iago Neira Arturo Blanco-gómez Elena Pazos carlos Peinador Hao Li Marcos D.garcía Departamento de Química and Centro de Investigacións Científicas Avanzadas(CICA) Facultade de CienciasUniversidade da Coruña15071 A CoruñaSpain Department of Chemistry Zhejiang UniversityHangzhou 310027China

We present herein the implementation of pH-responsiveness into a new polycationic macrobicyclic structure,namely what we have termed the“red cage”.The hydrolytically-stable cryptand-like compound has been prepared in a relatively high yield in aqueous media by a kinetically-controlled hydrazone-exchange reaction,promoted by the unusual high stability of the new hydrazone CvN bonds *** organic media the macrobicycle was found not able to complex model aromatic *** buffered aqueous solutions,as a comparison,the“red cage”was found able to recognize them,but the binding was observed to be more efficient in acidic form of the cyclophane compared with its conjugate base.

关键词： bonds conjugate media