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Large Eddy Simulation of the By-pass Transition Process under Different Inlet Turbulence Conditions

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Journal of Thermal Science 2021年第6期30卷 2112-2121页

作者： BARSI Dario COSTA carlo LENGANI Davide SIMONI Daniele UBALDI Marina DIME-University of Genova Via Montallegro 11-16145 GenovaItaly

The transition process of the boundary layer developing over a flat plate with elevated inlet Free Stream Turbulence Intensity(FSTI)has been studied by means of Large Eddy Simulation(LES).To this purpose,four cases with different inflow disturbances have been tested varying the magnitude and the length scale of *** has been performed by using the finite-volume ANSYS Fluent *** computational domain,which was constituted by a rectangular domain with a zero thickness plate,was based on an ERCOFTAC test case in order to provide a validation with a well-known set of data by comparing the boundary layer integral parameters and mean and fluctuating streamwise velocity *** four cases were discussed within the paper by looking at classical statistical properties as well as advanced post-processing *** was shown that the decrease in the free stream turbulence level postpones the transition location,whereas the variation of the integral length scale has a very low influence on the distribution of the time-mean flow *** Orthogonal Decomposition(POD)has been applied to the instantaneous LES flow fields in order to provide a statistical representation of the structures responsible for transition and their response to free-stream turbulence intensity and length *** presence of vortical filaments parallel to the wall,typically referred as boundary layer streaks,is clearly identified;their characteristic dimensions and how they change as a function of FSTI properties were analyzed within the paper.

关键词： by-pass transition Large Eddy Simulation(LES) Proper Orthogonal Decomposition(POD) boundary layer streaks

Detecting Singularities with Harmonic Wavelets

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Journal of Donghua University(English Edition) 2009年第5期26卷 544-548页

作者： CATTANI carlo 杨建国 DiFarma University of Salerno Via Ponte Don Melillo College of Mechanical Engineering Donghua University

A simple method,based on harmonic wavelet analysis is proposed for the decomposition of a given energy bounded signal into a periodic signal and a *** a denoising method,the first part signal it might represent a smooth periodic function while the pulse is a singular unpredicted perturbation (taken as a fault).It will be shown that,under some general conditions,by a simple projection into two disjoint space of functions we can easily separate the periodic component of the signal from the fault (represented by the singular pulse).

关键词： wavelets signal noise Fourier series

Paediatric retinal detachment:a review

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International Journal of Ophthalmology(English edition) 2017年第10期10卷 1592-1603页

作者： Raffaele Nuzzi carlo Lavia Roberta Spinetta Eye Clinic Department of Surgical SciencesUniversity of Turin

Paediatric retinal detachment（PRD）is an uncommon and challenging disease;it differs from adult detachments in etiology,anatomical characteristics,management and *** can be particularly challenging,even for the most expert paediatric surgeons due to the higher prevalence of total retinal detachments,late diagnosis and bilateral involvement with respect to those which occur in ***,the anatomical success,when achieved,is frequently not related to a functional *** adverse events,refractive errors and amblyopia may additionally undermine the final *** to date there are few reviews regarding the approach of retinal detachment in children,mainly dealing with rhegmatogenous retinal *** this review,rhegmatogenous,retinopathy of prematurityrelated and Coats’-related PRDs were *** available literature from the last decades were reviewed and ***,etiology and clinical presentation,together with therapeutic approaches and outcomes have been reviewed and discussed.

关键词： paediatric retinal detachment paediatric rhegmatogenous retinal detachment retinopathy of prematurity Coats' disease

The elegance of a macrophage

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Cellular & Molecular Immunology 2018年第3期15卷 196-198页

作者： Maria De Santis Massimo Locati carlo Selmi Rheumatology and Clinical Immunology Humanitas Research HospitalRozzanoItaly Laboratory of Leukocyte Biology Humanitas Research HospitalRozzanoItaly BIOMETRA Department University of MilanMilanItaly

In the latest issue of Nature Immunology,Piccolo et al.1 elegantly explored the effect of coexisting interferon-γ(IFN-γ)and interleukin 4(IL-4)antagonistic signals on macrophage transcriptional and epigenetic profiles and,interestingly,identified a plastic cross-talk as opposed to mutually exclusive programs between M1 and M2 polarized *** results support the fascinating hypothesis that transcriptional and epigenetic reprogramming overcame genetics to drive the evolution of eukaryotic organisms.A rapid reshaping of chromatin acetylation redirected the expression of hundreds of genes under the control of a few transcription factors in response to two coexisting but opposing signals that indicated inflammation and its resolution simultaneously.

关键词： macrophage interferon inflammation

Occupational exposures and colorectal cancers:A quantitative overview of epidemiological evidence

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World Journal of Gastroenterology 2014年第35期20卷 12431-12444页

作者： Enrico Oddone carlo Modonesi Gemma Gatta Department of Public Health Experimental and Forensic MedicineOccupational Medicine UnitUniversity of Pavia Department of Biosciences Natural History MuseumUniversity of Parma Department of Preventive and Predictive Medicine Evaluative Epidemiology UnitFondazione IRCCS Istituto Nazionale dei Tumori

A traditional belief widespread across the biomedical community was that dietary habits and genetic predisposition were the basic factors causing colorectal *** more recent times,however,a growing evidence has shown that other determinants can be very important in increasing(or reducing) incidence of this *** hypothesis that environmental and occupational risk factors are associated with colorectal cancer is gaining ground,and high risks of colorectal cancer have been reported among workers in some industrial *** aim of this study was to investigate the epidemiologic relationship between colorectal cancer and occupational exposures to several industrial activities,by means of a scientific literature review and *** work pointed out increased risks of colorectal cancer for labourers occupied in industries with a wide use of chemical compounds,such as leather(RR = 1.70,95%CI:1.24-2.34),basic metals(RR = 1.32,95%CI:1.07-1.65),plastic and rubber manufacturing(RR = 1.30,95%CI:0.98-1.71 and RR = 1.27,95%CI:0.92-1.76,respectively),besides workers in the sector of repair and installation of machinery exposed to asbestos(RR = 1.40,95%CI:1.07-1.84).Based on our results,the estimated crude excess risk fraction attributable to occupational exposure ranged from about 11% to about 15%.However,homogeneous pattern of association between colorectal cancer and industrial branches did not emerge from this review.

关键词： Colorectal cancer Occupational exposures Public health Chemical compounds Basic metals Meta analysis

Phase-matching-free parametric oscillators based on two-dimensional semiconductors

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Light(Science & Applications) 2018年第1期7卷 992-1000页

作者： Alessandro Ciattoni Andrea Marini carlo Rizza Claudio Conti Consiglio Nazionale Delle Ricerche(CNR-SPIN) Via Vetoio 1067100 L’AquilaItaly Department of Physical and Chemical Sciences University of L’AquilaVia Vetoio 1067100 L’AquilaItaly Institute for Complex Systems(ISC-CNR) Via dei Taurini 1900185 RomeItaly ICFO-Institut de Ciencies Fotoniques The Barcelona Institute of Science and Technology08860 CastelldefelsBarcelonaSpain Department of Industrial and Information Engineering and Economics University of L’AquilaVia G.Gronchi 18I-67100 L’AquilaItaly Department of Physics University SapienzaPiazzale Aldo Moro 500185 RomeItaly

Optical parametric oscillators are widely used as pulsed and continuous-wave tunable sources for innumerable applications,such as quantum technologies,imaging,and biophysics.A key drawback is material dispersion,which imposes a phase-matching condition that generally entails a complex design and setup,thus hindering tunability and *** we show that the burden of phase-matching is surprisingly absent in parametric microresonators utilizing mono-layer transition-metal dichalcogenides as quadratic nonlinear *** the exact solution of nonlinear Maxwell equations and first-principle calculations of the semiconductor nonlinear response,we devise a novel kind of phase-matching-free miniaturized parametric oscillator operating at conventional pump *** find that different two-dimensional semiconductors yield degenerate and non-degenerate emission at various spectral regions due to doubly resonant mode excitation,which can be tuned by varying the incidence angle of the external pump *** addition,we show that high-frequency electrical modulation can be achieved by doping via electrical gating,which can be used to efficiently shift the threshold for parametric *** results pave the way for the realization of novel ultra-fast tunable micron-sized sources of entangled photons—a key device underpinning any quantum *** miniaturized optical parametric oscillators may also be employed in lab-on-chip technologies for biophysics,detection of environmental pollution and security.

关键词： parametric matching degenerate

Systemic Risks: A Homomorphic Approach on the Basis of Complexity Science

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International Journal of Disaster Risk Science 2018年第3期9卷 292-305页

作者： Klaus Lucas Ortwin Renn carlo Jaeger Saini Yang Institute of Technical Thermodynamics Aachen University Institute for Advanced Sustainability Studies (IASS) Economic and Social Science Department University of Stuttgart Academy of Disaster Reduction and Emergency Management School of Geography Beijing Normal University Global Climate Forum Key Laboratory of Environmental Change and Natural Disasters Ministry of Education Beijing Normal University

Although the notion of systemic risk gained prominence with respect to financial systems, it is a generic term that refers to risks of increasing importance in many domains—risks that cannot be tackled by conventional techniques of risk management and governance. We build on a domain-overarching definition of systemic risks by highlighting crucial properties that distinguish them from conventional risks and plain disasters. References to typical examples from various domains are included. Common features of systemic risks in different domains—such as the role of agents and emergence phenomena, tipping and cascading, parameters indicating instability, and historicity—turn out to be more than noncommittal empirical observations. Rather these features can be related to fundamental theory for relatively simple and well-understood systems in physics and chemistry. A crucial mechanism is the breakdown of macroscopic patterns of whole systems due to feedback reinforcing actions of agents on the microlevel, where the reinforcement is triggered by boundary conditions moving beyond critical tipping *** the whole article, emphasis is placed on the role of complexity science as a basis for unifying the phenomena of systemic risks in widely different domains.

关键词： Complexity science Integrated risk governance Multiagent modeling Systemic risks

Injectable versus oral first-line multiple sclerosis therapies:knows and unknowns from observational studies

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Neural Regeneration Research 2022年第3期17卷 567-568页

作者： Emanuele D’Amico Aurora Zanghì carlo Avolio Department“G.F.Ingrassia” MS CenterUniversity of CataniaCataniaItaly Department of Medical and Surgical Sciences University of Foggia Multiple Sclerosis Center Department of NeurosciencesPoliclinico Riuniti HospitalFoggiaItaly

The approval of oral disease modifying therapies(DMTs) for relapsing-remitting multiple sclerosis(RRMS) has changed considerably the therapeutic scenario and they often represent the first therapeutic choice for patie... 详细信息

关键词： al. therapies sclerosis

Experimental Investigation of the Rail Pressure Fluctuations Correlated with Fuel Properties and Injection Settings

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Automotive Innovation 2021年第2期4卷 215-226页

作者： carlo Coratella Lewis Parry Yanfei Li Hongming Xu School of Mechanical Engineering University of BirminghamEdgbastonBirmingham B152TTUK State Key Laboratory of Automotive Safety and Energy Tsinghua UniversityBeijingChina

Injection-induced rail pressure fluctuations are proven to cause nonuniform spray *** fluctuations are also responsible for generating lower injection pressures,to the detriment of jet penetration length and break-up *** the vast literature dealing with such issues,several aspects of rail pressure fluctuations remain ***,the need for compliance with the emission legislation has shed light on the potential of alternative fuels,which represent a pathway for sustainable *** scenario has motivated the present study dealing with the assessment of the time history of rail pressure correlated with fuel *** have been performed using a last-generation common rail injection equipment under various injection settings,employing diesel and 2-methylfuran-diesel *** paper describes the research activity and aims to provide new insights into the correlation of rail pressure fluctuations with fuel properties.

关键词： Rail pressure fluctuations Wave propagation Viscosity Bulk modulus 2-Methylfuran Fuel blend