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世界核心医学期刊文摘（心脏病学分册） 2005年第2期1卷 44-45页

作者： r.mr.z Mor.no A. cardenal r. Per. C. 艾文婷 Ser.icio de Car.iologa Complejo Hospitalario Cd. de Jaen Avda Ejercito Espanol 10 23007 Jaén Spain

Backgr.und: Tr.ponin I concentr.tions ar. fr.quently elevated following per.ut aneous cor.nar. inter.ention(PCI) even in pr.cedur.s without complications and a r. consider.d, by some, as pr.dictive of long ter. mor.idity and mor.ality. We assessed whether.post PCI tr.ponin I concentr.tions bor. any r.lationship to cl inical, angiogr.phic and in labor.tor. minor.adver.e events indicative of myoca r.ial injur. and evaluated, in follow up, whether.these levels ar. useful as a pr.dictive mar.er. of adver.e events. Methods: Patients(n=147) who wer. schedule d for.PCI for.stent placement wer. pr.spectively studied. In labor.tor. events r.cor.ed wer. pr.tr.cted chest pain, electr.car.iogr.phic changes, slow flows, d issections and later.l br.nch affectation. Tr.ponin I and cr.atinine kinase MB f r.ction (CK MB) mass wer. measur.d at baseline and postpr.cedur.. Mean clinical follow up was for.10.4±3.6 months. r.sults: Dur.ng PCI, at least one adver.e event occur.ed in 34%of patients and, in 38%of them, ther. was an elevation of tr.ponin I as compar.d to 5.1%of those patients without any adver.e event (r.l ative r.sk=7.4; Pr.ponin I concentr.tions occur.ed in 16 .3%of all patients, 79.2%associated with an AE. CK MB was elevated in 15.6%o f patients. On multivar.ate analysis, pr.tr.cted chest pain, later.l br.nch invo lvement and slow flow r.mained statistically significant in r.lation to post pr.ocedur. elevations of tr.ponin I concentr.tions. Clinical follow up showed a po or.r.pr.gnosis in patients who had had elevated tr.ponin I concentr.tions. Concl usions: In labor.tor. adver.e event pr.dict elevated postpr.cedur. tr.ponin I c oncentr.tions which ar. associated with myocar.ial injur.. These elevations, in tur., pr.dict poor.r.medium ter. clinical outcomes.

关键词：肌损害预后价值支架置入术肌钙蛋白持续性胸痛介入治疗测量基血管造影多元分析肌损伤

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诗刊 2021年第11期 59-64页

作者： [尼加拉瓜]埃尔内斯托•卡德纳尔赵振江(译) 不详

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Stability of Pr.jection Methods for.Incompr.ssible Flows Using High Or.er.Pr.ssur.-Velocity Pair. of Same Degr.e:Continuous and Discontinuous Galer.in For.ulations

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Communications in Computational Physics 2014年第8期16卷 817-840页

作者： E.Fer.er.D.Moxey r.H.J.Willden S.J.Sher.in ETSIA–School of Aer.nautics Universidad Politecnica de MadridPza.Cardenal Cisneros 3MadridE-28040Spain. Depar.ment of Aer.nautics Imperial College LondonLondonSW72AZUK. Depar.ment of Engineer.ng Science University of OxfordParks RoadOxfordOX13PJUK.

This paper.pr.sents limits for.stability of pr.jection type schemes when using high or.er.pr.ssur.-velocity pair. of same *** high or.er.h/p var.ational methods encompassing continuous and discontinuous Galer.in for.ulations ar. used to explain pr.viously obser.ed lower.limits on the time step for.pr.jection type schemes to be stable[18],when h-or.p-r.finement str.tegies ar. *** addition,the analysis included in this wor. shows that these stability limits do not depend only on the time step but on the pr.duct of the latter.and the kinematic viscosity,which is of par.icular.impor.ance in the study of high r.ynolds number.*** show that high or.er.methods pr.ve advantageous in stabilising the simulations when small time steps and low kinematic viscosities ar. *** upon this analysis,we demonstr.te how the effects of this instability can be r.duced in the discontinuous scheme by intr.ducing a stabilisation ter. into the global ***,we show that these lower.limits ar. compatible with Cour.ntFr.edr.chs-Lewy(CFL)type r.str.ctions,given that a sufficiently high polynomial or.er.or.a mall enough mesh spacing is selected.

关键词： Incompr.ssible Navier.Stokes equations pr.jection methods velocity-cor.ection continuous Galer.in discontinuous Galer.in inf-sup LBB condition.

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认知运动干预对轻度认知损害和轻中度阿尔茨海默病患者有益

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世界核心医学期刊文摘（神经病学分册） 2005年第7期1卷 37-37页

作者： Olazar.an J. Muniz r. r.isber. B. 周永 Depar.amento de In vestigaci'on Fundaci'on Maria WolffCardenal Silceo 14 28002 Madrid Spain Dr.

Objective: To evaluate the efficacy of a cognitive-motor.pr.gr.m in patients with ear.y Alzheimer.disease (AD) who ar. tr.ated with a cholinester.se inhibito r.(ChEI). Methods: Patients with mild cognitive impair.ent (MCI) (12), mild AD(4 8), and moder.te AD (24) (Global Deter.or.tion Scale stages 3, 4, and 5) wer. r. ndomized to r.ceive psychosocial suppor. plus cognitive-motor.inter.ention (exp er.mental gr.up) or.psychosocial suppor. alone (contr.l gr.up). Cognitive-motor.inter.ention (CMI) consisted of a 1-year.str.ctur.d pr.gr.m of 103 sessions of cognitive exer.ises, plus social and psychomotor.activities. The pr.mar. effica cy measur. was the cognitive subscale of the AD Assessment Scale (ADAS-cog). Se condar. efficacy measur.s wer. the Mini-Mental State Examination,the Functional Activities Questionnair., and the Ger.atr.c Depr.ssion Scale. Evaluations wer. conducted at 1, 3, 6, and 12 months by blinded evaluator.. r.sults: Patients in the CMI gr.up maintained cognitive status at month 6, wher.as patients in the co ntr.l gr.up had significantly declined at that *** r.sponse was highe r.in the patients with fewer.year. of for.al education. In addition, mor. patien ts in the exper.mental gr.up maintained or.impr.ved their.affective status at mo nth 12 (exper.mental gr.up, 75%; contr.l gr.up, 47%; p =0.017). Conclusions: A long-ter. CMI in ChEI-tr.ated ear.y Alzheimer.disease patients pr.duced addit ional mood and cognitive benefits.

关键词：轻度认知损害阿尔茨海默病运动干预认知功能胆碱酯酶抑制剂 impair.ent ADAS 老年抑郁社会心理支持主要疗效

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