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Porous silicon carbide coated with tantalum as potential material for bone implants

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Regenerative Biomaterials 2020年第5期7卷 453-459页

作者： Zhijie Ma Jingyu Li fang cao Jiahui Yang Rong Liu Dewei Zhao Faculty of Electronic Information and Electrical Engineering School of Biomedical EngineeringDalian University of TechnologyNo.2 Linggong RoadGanjingzi DistrictDalianLiaoning 116024China Orthopaedic Department Affiliated ZhongShan Hospital of Dalian University No.6 Jiefang StreetZhongshan DistrictDalianLiaoning 116001China

Porous silicon carbide(SiC)has a specific biomorphous microstructure similar to the trabecular microstructure of human *** with that of bioactive ceramics,such as calcium phosphate,SiC does not induce spontaneous interface bonding to living *** this study,bioactive tantalum(Ta)metal deposited on porous SiC scaffolds by chemical vapour deposition was investigated to accelerate osseointegration and improve the bonding to *** electron microscopy indicated that the Ta coating evenly covered the entire scaffold ***-dispersive spectroscopy and X-ray diffraction analysis showed that the coating consisted of Ta *** bonding strength between the Ta coating and the SiC substrate is *** yield strength of porous SiC with a Ta coating(pTa)was 45.862.9MPa,the compressive strength was 61.463.2MPa and the elasticmodulus was*** MG-63 human osteoblasts were co-cultured with pTa,osteoblasts showed good adhesion and spreading on the surface of the pTa and its porous structure,which showed that it has excellent bioactivity and *** further study the osseointegration properties of *** and porous titanium(pTi)were implanted into the femoral neck of goats for 12weeks,*** Van-Gieson staining of histological sections results that the pTa group had better osseointegration than the pTi *** results indicate that coating bioactive Ta metal on porous SiC scaffolds could be a potential material for bone substitutes.

关键词： porous SiC scaffold tantalum coating chemical vapour deposition bone implant material

Research progress of ionic liquids-based gels in energy storage,sensors and antibacterial

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Green Chemical Engineering 2021年第4期2卷 368-383页

作者： Yi-Ru Gao Jian-fang cao Yang Shu Jian-Hua Wang Department of Chemistry College of SciencesNortheastern UniversityShenyang110819China

In the past few years,ionic liquids(ILs)-based gels(gels contain ILs)have become a research ***-based gels combine the properties of gels with intrinsic ILs *** to the existence form and function of the ILs in the gel,the ILs-based gels are divided into three *** is ILs hydrogels which the PILs,ILs polymerized into poly-ionic liquids,copolymerized with other polymers served as the continuous phase in the gel *** type of gel can usually absorb water and is an ILs *** other is ionic gels that are usually synthesized by high-molecular organic polymers as spatial network structure and ILs as a dispersed phase,which maintained the good performance of *** third one is that the ILs acts as both the continuous phase and the dispersed phase of the *** all research fields,the pursuit of new materials aims at functional materials,which enhances specific and efficiency,and ultimately *** application of ILs-based gels ranges from energy storage,sensing,electrochemical devices,to antibacterial and gas *** synthesis methods have different performances and applications of ILs-based *** purpose of this review is to provide the latest developments on ILs-based gels,perspectives on several applications,and some challenges that need to be aware of in this field.

关键词： Electrolytes Lithium ion battery Supercapacitors Energy storage Sensor Antibacterial

Stomatal dynamics are regulated by leaf hydraulic traits and guard cell anatomy in nine true mangrove species

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Plant Diversity 2024年第3期46卷 395-405页

作者： Ya-Dong Qie Qi-Wei Zhang Scott A.M.McAdam Kun-fang cao State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources College of ForestryGuangxi UniversityNanning 530004China Guangxi Key Laboratory of Forest Ecology and Conservation College of ForestryGuangxi UniversityNanning 530004China Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection Ministry of EducationGuangxi Normal UniversityGuilin 541001China Guangxi Key Laboratory of Landscape Resources Conservation and Sustainable Utilization in Lijiang River Basin Guangxi Normal UniversityGuilin 541001China Purdue Center for Plant Biology Department of Botany and Plant PathologyPurdue UniversityWest LafayetteIN 47907USA

Stomatal regulation is critical for mangroves to survive in the hyper-saline intertidal zone where water stress is severe and water availability is highly ***,very little is known about the stomatal sensitivity to vapour pressure deficit(VPD)in mangroves,and its co-ordination with stomatal morphology and leaf hydraulic *** measured the stomatal response to a step increase in VPD in situ,stomatal anatomy,leaf hydraulic vulnerability and pressure-volume traits in nine true mangrove species of five families and collected the data of genome *** aimed to answer two questions:(1)Does stomatal morphology influence stomatal dynamics in response to a high VPD in mangroves?with a consideration of possible influence of genome size on stomatal morphology;and(2)do leaf hydraulic traits influence stomatal sensitivity to VPD in mangroves?We found that the stomata of mangrove plants were highly sensitive to a step rise in VPD and the stomatal responses were directly affected by stomatal anatomy and hydraulic ***,denser stomata was correlated with faster stomatal closure at high VPD across the species of Rhizophoraceae,and stomata size negatively and vein density positively correlated with genome *** negative leaf osmotic pressure at the full turgor(πo)was related to higher operating steady-state stomatal conductance(gs);and a higher leaf capacitance(Cleaf)and more embolism resistant leaf xylem were associated with slower stomatal responses to an increase in *** addition,stomatal responsiveness to VPD was indirectly affected by leaf morphological traits,which were affected by site salinity and consequently leaf water *** results demonstrate that mangroves display a unique relationship between genome size,stomatal size and vein packing,and that stomatal responsiveness to VPD is regulated by leaf hydraulic traits and stomatal *** work provides a quantitative framework to better understand of stomatal regulation in mangroves

关键词： Stomatal temporal kinetics Vapour-pressure deficit(VPD) Leaf water relations Leaf hydraulic vulnerability Leaf osmotic potential Genome size

Artificial intelligence for the detection of glaucoma with SD-OCT images:a systematic review and Meta-analysis

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 408-419页

作者： Nan-Nan Shi Jing Li Guang-Hui Liu Ming-fang cao Department of Ophthalmology Affiliated People’s Hospital(Fujian Provincial People’s Hospital)Fujian University of Traditional Chinese MedicineFuzhou 350004Fujian ProvinceChina Eye Institute of Integrated Chinese and Western Medicine Fujian University of Traditional Chinese MedicineFuzhou 350004Fujian ProvinceChina

●AIM:To quantify the performance of artificial intelligence(AI)in detecting glaucoma with spectral-domain optical coherence tomography(SD-OCT)images.●METHODS:Electronic databases including PubMed,Embase,Scopus,ScienceDirect,ProQuest and Cochrane Library were searched before May 31,2023 which adopted AI for glaucoma detection with SD-OCT *** pieces of the literature were screened and extracted by two ***-analysis,Meta-regression,subgroup,and publication of bias were conducted by *** risk of bias assessment was performed in Revman5.4 using the QUADAS-2 tool.●RESULTS:Twenty studies and 51 models were selected for systematic review and *** pooled sensitivity and specificity were 0.91(95%CI:0.86–0.94,I2=94.67%),0.90(95%CI:0.87–0.92,I2=89.24%).The pooled positive likelihood ratio(PLR)and negative likelihood ratio(NLR)were 8.79(95%CI:6.93–11.15,I2=89.31%)and 0.11(95%CI:0.07–0.16,I2=95.25%).The pooled diagnostic odds ratio(DOR)and area under curve(AUC)were 83.58(95%CI:47.15–148.15,I2=100%)and 0.95(95%CI:0.93–0.97).There was no threshold effect(Spearman correlation coefficient=0.22,P>0.05).●CONCLUSION:There is a high accuracy for the detection of glaucoma with AI with SD-OCT *** application of AI-based algorithms allows together with“doctor+artificial intelligence”to improve the diagnosis of glaucoma.

关键词： artificial intelligence spectral-domain optical coherence tomography glaucoma Meta-analysis

Hepatitis C Virus non-structural 5A abrogates signal transducer and activator of transcription-1 nuclear translocation induced by IFN-α through dephosphorylation

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World Journal of Gastroenterology 2007年第30期13卷 4080-4084页

作者： Guo-Zhong Gong Jie cao Yong-fang Jiang Yang Zhou Bo Liu Institute of Hepatology and Department of Infectious Diseases The Second Xiangya Hospital Central South University Changsha 410011 Hunan Province China

AIM： To study the effect of Hepatitis C virus nonstructural 5A （HCV NSSA） on IFNα induced signal transducer and activator of transcription-1 （STAT1） phosphorylation and nuclear translocation.METHODS： Expression of STAT1 Tyr701 phosphorylation at different time points was confirmed by Western blot, and the time point when p-STAT1 expressed most, was taken as the IFN induction time for further studies. Immunocytochemistry was used to confirm the successful transient transfection of NS5A expression plasmid. Immunofluorescene was performed to observe if there was any difference in IFNα-induced STAT1 phosphorylation and nuclear translocation between HCV NSSA-expressed and non-HCV NSSA-expressed cells. Western blot was used to compare the phosphorylated STAT1 protein of the cells.RESULTS： Expression of HCV NS5A was found in the cytoplasm of pCNS5A-transfected Huh7 cells, but not in the PRC/ CMV transfected or non-transfected cells, STAT1 Tyr701 phosphorylation was found strongest in 30 min of IFN induction, STAT1 phosphorylation and nuclear import were much less in the presence of HCV NS5A protein in contrast to pRC/CMV-transfected and non-transfected cells under fluorescent microscopy, which was further confirmed by Western blot.CONCLUSION： HCV NSSA expression plasmid is successfully transfected into Huh7 cells and HCV NS5A protein is expressed in the cytoplasm of the cells. IFN-α is able to induce STAT1 phosphrylation and nuclear translocation, and this effect is inhibited by HCV NS5A protein, which might be another possible resistance mechanism to interferon alpha therapy.

关键词： Hepatitis C virus nonstructural protein 5A IFN-α Signal transducer and activator of transcription (STAT1) Phosphorylation Nuclear translocation

No-tillage effects on grain yield and nitrogen requirements in hybrid rice transplanted with single seedlings: Results of a long-term experiment

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Journal of Integrative Agriculture 2019年第1期18卷 24-32页

作者： HUANG Min CHEN Jia-na cao fang-bo ZOU Ying-bin Norman Uphoff Southern Regional Collaborative Innovation Center for Grain and Oil Crops (CICGO) Hunan Agricultural University International Programs-College of Agriculture and Life Sciences (IP-CALS) Cornell University

This study was conducted to determine whether,and if so how,the grain yield and nitrogen(N) requirements of hybrid rice transplanted as single seedlings are affected by no-tillage(NT) practices.A fixed field experiment was done at the Experimental Farm of Hunan Agricultural University in Changsha,Hunan Province,China,from 2004 to *** yield and yield attributes(panicle number per m2,spikelet number per panicle,spikelet filling percentage,grain weight,total biomass,and harvest index) were evaluated as well as the N-use characteristics(total N uptake,internal N-use efficiency,and N requirements) of hybrid rice transplanted as single seedlings comparing NT with conventional tillage(CT).A significant finding was that there were no significant differences in grain yield,yield attributes,and N-use characteristics between CT and *** across the 11 years,grain yield and N requirements were 9.51 t ha^(-1) and 20.2 kg t^(-1) under CT and 9.33 t ha^(-1) and 20.0 kg t^(-1) under NT,*** were significant yearly variations in grain yield,yield attributes,and N-use characteristics observed under both CT and *** yearly variation in grain yield was related to simultaneous changes in spikelet number per panicle,grain weight,total biomass,and harvest ***,it was found that grain yield was positively correlated with internal N-use efficiency but negatively correlated with N *** is concluded that grain yield and N requirements in hybrid rice when transplanted as single seedlings are not affected adversely by *** results of this study suggest that(1) compatible relationships among yield attributes can be established in hybrid rice that is transplanted as single seedlings,and(2) higher grain yield and higher N-use efficiency can be concurrently achieved in hybrid rice transplanted as single seedlings.

关键词： grain yield hybrid rice nitrogen requirements no-tillage transplanting of single seedlings

A combined numerical tidal model for the Hangzhou Bay and Qiantang River

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Acta Oceanologica Sinica 1989年第4期8卷 485-496页

作者： cao Deming and fang Guohong Institute of Oceanology, Academia Sinica, Qingdao, China China

-In order to avoid prescribing open boundary condition on the upstream side of the Hangzhou Bay, in numerical simulation of the tides and residual currents of the Bay, a 1-D model for the Qiantang River is connected to the 2-D model for the Hangzhou Bay. The harmonic constants of diurnal constituent [ (K1+O1)/2],semidiurnal constituent (M2) and shallow water constituent (M4) are obtained. The results produced by the combined model are in better agreement with the observed ones than those produced solely by the original 2-D model. The combined model gives much more reliable results for tide-induced residual water level and current.

关键词： A combined numerical tidal model for the Hangzhou Bay and Qiantang River Bay

Lüroth Expansion Digits and Maclaurin’s Inequality

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Wuhan University Journal of Natural Sciences 2018年第6期23卷 471-474页

作者： LI Li cao fang TANG Shixin WU Yuhan School of Mathematics and Statistics Wuhan UniversityWuhan 430072 Hubei China The True Light Middle School in Guangzhou Guangzhou 510145 Guangdong China

It is well known that for almost all real number x, the geometric mean of the first n digits di（x） in the Lüroth expansion of x converges to a number K0 as n→∞. On the other hand, for almost all x, the arithmetric mean of the first n Lüroth expansion digits di（x） approaches infinity as n→∞. There is a sequence of refinements of the AM-GM inequality, Maclaurin＇s inequalities, relating the 1/k-th powers of the k-th elementary symmetric means of n numbers for 1≤k≤n. In this paper, we investigate what happens to the means of Lüroth expansion digits in the limit as one moves f（n） steps away from either extreme. We prove sufficient conditions on f（n） to ensure divergence when one moves away from the arithmetic mean and convergence when one moves f（n） steps away from geometric mean.

关键词： Luroth series expansion Maclaurin's inequalities arithmetic mean geometric mean

Why high grain yield can be achieved in single seedling machine-transplanted hybrid rice under dense planting conditions?

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Journal of Integrative Agriculture 2018年第6期17卷 1299-1306页

作者： HUANG Min SHAN Shuang-lü XIE Xiao-bing cao fang-bo ZOU Ying-bin Southern Regional Collaborative Innovation Center for Grain and Oil Crops (CICGO) Hunan Agricultural University

This study was conducted to identify the factors associated with high grain yield in single seedling machine-transplanted hybrid rice under dense planting conditions. Field experiments were done in Yong＇an Town, Hunan Province, China in 2015 and 2016. Two hybrid rice cultivars were grown under single seedling machine transplanting （SMT） and conventional machine transplanting （CMT） at a high planting density in each year. Grain yield and yield attributes were compared between SMT and CMT. Averaged across cultivars and years, grain yield was 12％ higher under SMT than under CMT. Plant height, basal stem width, and shoot and root dry weights were higher in seedlings for SMT than those for CMT. SMT had less maximum tiller number per m2 and consequently less panicle number per m2 than did CMT. Branch number per panicle, especially the secondary branch number per panicle, and spikelet number per cm of panicle length were more under SMT than under CMT, which resulted in more spikelet number per panicle under SMT than under CMT. SMT had higher or equal spikelet filling percentage than did CMT. The difference in grain weight between SMT and CMT was relatively small and inconsistent cross years. SMT had higher or equal total biomass and harvest index than did CMT. Dry weight per stem under SMT was heavier than that under CMT. Larger leaf area per stem was partly responsible for the heavier dry weight per stem under SMT than under CMT. Our study suggests that improvement in seedling quality, panicle size, and dry weight per stem are critical to the high grain yield in single seedling machine-transplanted hybrid rice under dense planting conditions.

关键词： grain yield hybrid rice machine transplanting single seedling