检索结果-南通市图书馆

Hepatocellular carcinoma: can li-RADS v2017 with gadoxetic-acid enhancement magnetic resonance and diffusion-weighted imaging improve diagnostic accuracy?

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2019年第5期25卷 622-631页

作者： Tong Zhang Zi-Xing Huang Yi Wei Han-Yu Jiang Jie Chen Xi-Jiao liu li-Kun Cao Ting Duan Xiao-Peng He Chun-Chao Xia Bin Song Department of Radiology Sichuan University West China Hospital

BACKGROUND The liver Imaging Reporting and Data System(li-RADS), supported by the American College of Radiology(ACR), has been developed for standardizing the acquisition, interpretation, reporting, and data collection of liver imaging examinations in patients at risk for hepatocellular carcinoma(HCC). Diffusionweighted imaging(DWI), which is described as an ancillary imaging feature of li-RADS, can improve the diagnostic efficiency of li-RADS v2017 with gadoxetic acid-enhanced magnetic resonance imaging(MRI) for *** To determine whether the use of DWI can improve the diagnostic efficiency of liRADS v2017 with gadoxetic acid-enhanced magnetic resonance MRI for *** In this institutional review board-approved study, 245 observations of high risk of HCC were retrospectively acquired from 203 patients who underwent gadoxetic acid-enhanced MRI from October 2013 to April 2018. Two readers independently measured the maximum diameter and recorded the presence of each lesion and assigned scores according to li-RADS v2017. The test was used to determine the agreement between the two readers with or without DWI. In addition, the sensitivity(SE), specificity(SP), accuracy(AC), positive predictive value(PPV), and negative predictive value(NPV) of li-RADS were *** index values were used to compare the diagnostic performance of liRADS with or without *** Almost perfect interobserver agreement was obtained for the categorization of observations with li-RADS(kappa value: 0.813 without DWI and 0.882 with DWI). For LR-5, the diagnostic SE, SP, and AC values were 61.2%, 92.5%, and71.4%, respectively, with or without DWI; for LR-4/5, they were 73.9%, 80%, and75.9% without DWI and 87.9%, 80%, and 85.3% with DWI; for LR-4/5/M, they were 75.8%, 58.8%, and 70.2% without DWI and 87.9%, 58.8%, and 78.4% with DWI; for LR-4/5/TIV, they were 75.8%, 75%, and 75.5% without DWI and 89.7%,75%, and 84.9% with DWI. The Youden index values of the li-RADS classification

关键词： Hepatocellular carcinoma liver Imaging Reporting and Data System Magnetic resonance imaging Diffusion-weighted imaging Diagnosis

卵黄高磷蛋白α-淀粉酶抑制肽的制备、鉴定及酶抑制动力学分析

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

食品工业科技 2025年第1期46卷 152-162页

作者：薛天睿吕彬斐张铭冉李灿张晓维天津科技大学食品科学与工程学院天津300457

为探索卵黄高磷蛋白肽(phosvitin phosphopeptide,PPP)对α-淀粉酶的抑制作用,使其能够调控血糖水平从而缓解Ⅱ型糖尿病,本研究以α-淀粉酶抑制率为指标酶解卵黄高磷蛋白制备PPP,利用酶抑制动力学实验分析PPP对α-淀粉酶的抑制类型,采... 详细信息

为探索卵黄高磷蛋白肽(phosvitin phosphopeptide,PPP)对α-淀粉酶的抑制作用,使其能够调控血糖水平从而缓解Ⅱ型糖尿病,本研究以α-淀粉酶抑制率为指标酶解卵黄高磷蛋白制备PPP,利用酶抑制动力学实验分析PPP对α-淀粉酶的抑制类型,采用液质联用鉴定后用分子对接筛选出高活性的α-淀粉酶抑制肽,最后验证其活性。结果表明,最优酶解条件为先经胰蛋白酶(加酶量7000 U/g)再经胃蛋白酶(加酶量60000 U/g)分别酶解6 h,制得的PPP在浓度7.81×10-3 mg/mL时具有最高α-淀粉酶抑制率70.69%±1.71%。PPP对α-淀粉酶的抑制类型为混合型抑制。鉴定筛选出了两种新型的高活性α-淀粉酶抑制肽FGTEPDAK和IWGR,经验证其IC50值分别为(0.80±0.14)×10-3 mg/mL和(1.80±0.31)×10-3 mg/mL,极显著低于阳性对照阿卡波糖(3.17±0.47)×10-3 mg/mL(P<0.01)。本研究揭示PPP可作为新型降糖物质,应用于缓解Ⅱ型糖尿病的功能性食品开发中。

关键词：卵黄高磷蛋白肽复合酶解 α-淀粉酶抑制剂分子对接酶抑制动力学

Tuning electronic structure ofδ-MnO_(2) by the alkali-ion(K,Na,li)associated manganese vacancies for high-rate supercapacitors

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2021年第5期30卷 245-258页

作者： Lengyuan Niu lijin Yan Zhengwei Lu Yinyan Gong Taiqiang Chen can li Xinjuan liu Shiqing Xu College of Optical and Electronic Technology China Jiliang UniversityHangzhou 311018ZhejiangChina College of Materials and Chemistry China Jiliang UniversityHangzhou 310018ZhejiangChina

Cation vacancies can bring numerous surprising characters due to its multifarious electron and orbit *** this work,d-MnO_(2) with alkali-ion(K,Na,li)associated manganese(Mn)vacancies is fabricated by a simple hydrothermal reaction,and the correlation between their electronic structure and pseudocapacitance are systematically ***/TEM images have shown that the morphology of MnO_(2) is obviously changed after the introducing of cation *** position of alkali-ion in MnO_(2) structure can be controlled by adjusting the ion *** patterns and Raman spectra demonstrate that the alkali-ion is embedded in Mn vacancies at low concentration,while entered the interlayer of MnO_(2) at high *** existence of Mn vacancies will resulting in the distortion of neighboring atoms,leading to the electronic delocalization,and thus enhancing the conductivity,pseudocapacitance and rate capability of MnO_(2).Accordingly,the specific capacitances of optimized 0.4 KMO,0.4 NaMO and 0.4 liMO samples are enhanced about 1.9,1.6 and 1.6 times compared to pure MnO_(2).Meanwhile,the rate performance has also been improved about 76%,46%and 42%,*** calculations further confirm that the Mn vacancies can generate additional occupancy states and cause an increase in carrier concentration,which will improve the conductivity and further boost the pseudocapacitance of MnO_(2).This result open up a promising approach to explore active and durable electrode materials.

关键词： Supercapacitor Manganese oxide Manganese vacancies Pseudocapacitance

窄食单胞菌对微藻在高浓度甲酸条件下光合生长的促进作用

在线全文

学校读者我要写书评

暂无评论

生物工程学报 2025年第1期41卷 230-241页

作者：邢蒙蒙郑伟杰王旺银曹旭鹏李灿中国科学院大连化学物理研究所辽宁大连116023 中国科学院大学北京101408

甲酸是一种重要的太阳燃料,具有很高的生物转化应用前景,尤其是与光合微藻相结合,理论上能最大化人工与生物光合成的优势。然而甲酸对微藻光合电子传递具有明显的抑制,限制了其应用,常规的改造和定向进化策略耗时且普适性不高。本文介... 详细信息

甲酸是一种重要的太阳燃料,具有很高的生物转化应用前景,尤其是与光合微藻相结合,理论上能最大化人工与生物光合成的优势。然而甲酸对微藻光合电子传递具有明显的抑制,限制了其应用,常规的改造和定向进化策略耗时且普适性不高。本文介绍了一条新的甲酸在光合微藻培养过程中的应用路线,通过将一株分离自微藻高甲酸进化过程的窄食单胞菌或其发酵产物与微藻进行共培养,解除了50 mmol/L甲酸根对莱茵衣藻光合活性的抑制,促进其光合生长,极大提升了胞内蛋白含量(约50%)。初步测试表明,这一策略也同样适用于小球藻和集胞藻,具有普适性。这一策略的提出有望打破甲酸介导的人工-生物杂化光合成技术瓶颈,建立更普适和高效的太阳光能驱动二氧化碳还原制备蛋白质的大宗生物质工艺。

关键词：太阳燃料甲酸蛋白质食品供给安全藻菌互作

基于增益管理非线性的超快光纤激光放大研究进展(特邀)

在线全文

学校读者我要写书评

暂无评论

红外与激光工程 2025年第1期54卷 45-58页

作者：李灿任博郭琨王涛吴坚冷进勇周朴国防科技大学前沿交叉学科学院湖南长沙410073 国防科技大学南湖之光实验室湖南长沙410073 国防科技大学高能激光技术湖南省重点实验室湖南长沙410073

增益管理非线性(Gain Managed Nonlinearity,GMN)光纤放大技术涉及一种超快激光在非线性自相位调制与有源光纤动态增益共同作用下的非线性吸引子,可在激光脉冲能量提升的同时实现上百倍的线性光谱展宽,因而成为近年来超快光纤激光领域... 详细信息

增益管理非线性(Gain Managed Nonlinearity,GMN)光纤放大技术涉及一种超快激光在非线性自相位调制与有源光纤动态增益共同作用下的非线性吸引子,可在激光脉冲能量提升的同时实现上百倍的线性光谱展宽,因而成为近年来超快光纤激光领域的研究热点。文中从GMN脉冲演化的基本原理出发,系统梳理了GMN光纤放大技术在近年来所取得的研究进展、及在多光子显微成像等领域的应用,并进一步展望了其未来发展趋势。

关键词：增益管理非线性放大超快光纤激光自相位调制掺镱光纤

One-pot remote desymmetrization/Peterson-olefination for the construction of silicon-stereogenic silyl ethers

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2023年第10期66卷 2797-2802页

作者： Wengang Guo Qian li Yan liu can li State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China

Chiral silyl ethers and silanols are important synthetic intermediates and bioactive *** this work,we developed a onepot remote desymmetrization/Peterson-olefination of silacyclopentene oxides with benzoic acids in the presence of Martin’s *** new methodology not only realizes the atom-economy of Peterson olefination,but also represents a catalytic method for synthesis of silicon-stereogenic silyl *** a bulky chiral phosphoric acid 4i as organocatalyst,the reactions proceeded efficiently to afford various olefin-functionalized organosilyl ethers in excellent diastereoelectivities(up to 25/1 d.r.)and high enantioselectivities(up to 94%ee).

关键词： asymmetric catalysis silicon-stereogenic silyl ether remote desymmetrization/Peterson-olefination bronsted acid catalysis

Local Discontinuous Galerkin Scheme for Space Fractional Allen–Cahn Equation

在线全文

学校读者我要写书评

暂无评论

Communications on Applied Mathematics and Computation 2020年第1期2卷 73-91页

作者： can li Shuming liu College of Sciences Xi’an University of TechnologyXi’an 710048China

This paper is concerned with the efficient numerical solution for a space fractional Allen–Cahn(AC)*** on the features of the fractional derivative,we design and analyze a semi-discrete local discontinuous Galerkin(LDG)scheme for the initial-boundary problem of the space fractional AC *** prove the optimal convergence rates of the semi-discrete LDG approximation for smooth ***,we test the accuracy and efficiency of the designed numerical scheme on a uniform grid by three *** simulations show that the space fractional AC equation displays abundant dynamical behaviors.

关键词： Fractional Allen-Cahn equation Local discontinuous Galerkin scheme Error estimates

Synthesis and hydrogen desorption kinetics of Mg_(2)FeH_(6)-and Mg_(2)CoH_(5)-based composites with in situ formed YH_(3)and Mg_(2)NiH_4 nanoparticles

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2023年第7期42卷 2335-2343页

作者： can li Zhi-Wen Wu Qing-An Zhang School of Materials Science and Engineering Anhui University of TechnologyMaanshan243002China

Mg_(2)FeH_(6)-and Mg_(2)CoH_(5)-based composites with in situ formed YH_(3)and Mg_(2)NiH_4 nanoparticles were synthesized by ball milling of Mg_(10)YNi+4Fe(in mole ratio)and Mg_(10)YNi+4Co powders,respectively,at4 MPa H_(2)followed by hydrogenation at 673 K for 60 h under a hydrogen pressure of 7 *** is found that the nanocrystalline YH_(3)and Mg_(2)NiH_4 particles are indeed embedded in Mg_(2)FeH_(6)and Mg_(2)CoH_(5)*** hydrogen desorption rates of Mg_(2)FeH_(6)-and Mg_(2)CoH_(5)-based composites are enhanced compared to those undoped Mg_(2)FeH_(6)and Mg_(2)CoH_(5)hydrides,respectively,due to the synergetic catalysis of nanosized YH_(3)and Mg_(2)NiH_4 *** finding provides us with an efficient and simple approach for the improvement in hydrogen desorption kinetics of Mg-based hydrogen storage materials.

关键词： Hydrogen storage Mg-based hydride Kinetics Catalytic effect

Photocatalysis in solar fuel production

在线全文

学校读者我要写书评

暂无评论

National Science Review 2015年第2期2卷 145-147页

作者： Hongxian Han can li State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of Sciences and Dalian National Laboratory for Clean Energy

With the increasing concerns on energy and environmental problems caused by the combustion of fossil fuels,solar energy becomes vitally important because it is the only viable renewable energy source that can replace ... 详细信息

关键词： PSP