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Numerical modeling of fracture propagation of supercritical CO_(2)compound fracturing

Journal of Rock Mechanics and Geotechnical Engineering 2024年第7期16卷 2607-2628页

作者： Hao Chen Yong Kang Wanchun Jin Changhai Li can cai School of Mechanical Engineering Southwest Petroleum UniversityChengdu610500China Laboratory of High-pressure Jet Theory and Application Technology Southwest Petroleum UniversityChengdu610500China Hubei Key Laboratory of Waterjet Theory and New Technology Wuhan UniversityWuhan430072China Sinopec International Petroleum Exploration and Production Corporation Beijing 100029China

The exploitation of shale gas is promising due to depletion of the conventional energy and intensification of the greenhouse *** this paper,we proposed a heat-fluid-solid coupling damage model of supercritical CO_(2)(SC-CO_(2))compound fracturing which is expected to be an efficient and environmentally friendly way to develop shale *** coupling model is solved by the finite element method,and the results are in good agreement with the analytical solutions and fracturing *** on this model,the fracture propagation characteristics at the two stages of compound fracturing are studied and the influence of pressurization rate,in situ stress,bedding angle,and other factors are *** results show that at the SC-CO_(2)fracturing stage,a lower pressurization rate is conducive to formation of the branches around main fractures,while a higher pressurization rate inhibits formation of the branches around main fractures and promotes formation of the main *** bedding and in situ stress play a dominant role in the fracture *** the in situ stress ratio(sx/sy)is 1,the presence of bedding can reduce the initiation pressure and failure ***,it will cause the fracture to propagate along the bedding direction,reducing the fracture *** rocks without bedding,hydraulic fracturing has the lengthening and widening effects for SC-CO_(2)induced *** shale,fractures induced at the hydraulic fracturing stage are more likely to be dominated by in situ stresses and have a shorter reorientation ***,fracture branches propagating along the maximum principal stress direction may be generated around the main fractures induced by SC-CO_(2)at the hydraulic fracturing *** the branches converge with the main fractures,fracture zones are easily formed,and thus the fracture complexity and damage area can be significantly *** results are instructive for the design and application of SC-CO_(2

关键词： Compound fracturing Fracture propagation Finite element method Damage evolution

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页岩气水平井暂堵坐封机制与可控暂堵压裂工艺

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断块油气田 2024年第3期31卷 432-438页

作者：李绍鹏李常兴周鹏蓝宝锋蔡灿钟涛贵州能源产业研究院有限公司非常规天然气研究所贵州贵阳550009 贵州页岩气勘探开发有限责任公司工程技术部贵州正安563400 贵州大学资源与环境工程学院贵州贵阳550025 西南石油大学机电工程学院四川成都610500 中国石化江汉石油工程有限公司页岩气开采技术服务公司湖北武汉430074

水平井暂堵转向压裂技术是页岩气增产的关键技术之一。文中采用流体动力学软件FLUENT与离散元方法(DEM)相结合的数值建模方法,研究了水平井暂堵转向压裂技术中暂堵球在井筒中的运移规律以及颗粒间的相互作用。通过建立DEM-DDPM耦合模型... 详细信息

水平井暂堵转向压裂技术是页岩气增产的关键技术之一。文中采用流体动力学软件FLUENT与离散元方法(DEM)相结合的数值建模方法,研究了水平井暂堵转向压裂技术中暂堵球在井筒中的运移规律以及颗粒间的相互作用。通过建立DEM-DDPM耦合模型发现,施工排量、暂堵球密度、暂堵球直径和压裂液黏度是影响暂堵球坐封效果的主要因素。模拟结果表明:当施工排量在4~6 m^(3)/min时,暂堵球的密度小于或等于流体密度;射孔炮眼磨蚀率在6.15%以内可以有效提高封堵效率;同时,随着压裂液黏度的增加,封堵效率先升后降。该研究结果对于优化水平井压裂暂堵球用量以及施工工艺具有重要的理论意义和指导价值。

关键词：暂堵转向压裂暂堵球运移 DEM-DDPM耦合坐封

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Composite rock-breaking of high-pressure CO_(2)jet&polycrystallinediamond-compact(PDC)cutter using a coupled SPH/FEM model

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International Journal of Mining Science and Technology 2022年第5期32卷 1115-1124页

作者： can cai Pei Zhang Daping Xu Xianpeng Yang Yingfang Zhou School of Mechanical Engineering Southwest Petroleum UniversityChengdu 610500China Key Laboratory of Groundwater Resources and Environment Jilin UniversityMinistry of EducationChangchun 130021China Laboratory of High-pressure Jet Theory and Application Technology Southwest Petroleum UniversityChengdu 610599China School of Engineering University of AberdeenAberdeen AB243FXUnited Kingdom School of Intelligent Manufacturing Panzhihua UniversityPanzhihua 617000China

CO_(2) drilling is a promising underbalance drilling technology with great advantages,such as lower cutting force,intense cooling and excellent ***,in the underbalance drilling,the mechanism of the coupling CO_(2) jet and polycrystalline-diamond-compact(PDC)cutter are still ***,we established a coupled smoothed particle hydrodynamics/finite element method(SPH/FEM)model to simulate the composite rock-breaking of high-pressure CO_(2) jet&PDC *** with the experimental research results,the mechanism of composite rock-breaking is studied from the perspectives of rock stress field,cutting force and jet *** results show that the composite rock-breaking can effectively relieve the influence of vibration and shock on PDC ***,the high-pressure CO_(2) jet has a positive effect on carrying rock debris,which can effectively reduce the temperature rising and the thermal wear of the PDC *** addition,the effects of CO_(2) jet parameters on composite rock-breaking were studied,such as jet impact velocity,nozzle diameter,jet injection angle and impact *** studies show that when the impact velocity of the CO_(2) jet is greater than 250 m/s,the CO_(2) jet could quickly break the *** is found that the optimal range of nozzle diameter is 1.5–2.5 mm,the best injection angle of CO_(2) jet is 60,the optimal impact distance is 10 times the nozzle *** above studies could provide theoretical supports and technical guidance for composite rock-breaking,which is useful for the CO_(2) underbalance drilling and drill bit design.

关键词： C0_(2)drilling High-pressure C0_(2)jet&PDC cutter Composite rock-breaking Experimental study SPH/FEM method

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油气井井下切割技术发展现状及趋势

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西安石油大学学报（自然科学版） 2024年第1期39卷 89-96,113页

作者：蔡灿曾浪刘家炜樊康康曹文洋周圣文曾薪西南石油大学机电工程学院高压射流理论与应用技术实验室四川成都610500 油气装备教育部重点实验室四川成都610500 油气藏地质及开发工程全国重点实验室(西南石油大学) 四川成都610500 中石油工程技术研究院江汉机械研究所有限公司湖北荆州434000

油气开发后期,退役井数量急剧增加,完井修井作业中套管磨损、卡钻等问题突出,退役经济耗费显著增加。为最大限度减少卡钻和退役经济耗费,有必要开展新型套管切割技术及装备的研发与应用。首先,总结了现阶段井下管柱切割技术的主要类型... 详细信息

油气开发后期,退役井数量急剧增加,完井修井作业中套管磨损、卡钻等问题突出,退役经济耗费显著增加。为最大限度减少卡钻和退役经济耗费,有必要开展新型套管切割技术及装备的研发与应用。首先,总结了现阶段井下管柱切割技术的主要类型、工作原理和配套装备,包括机械切割、磨料射流切割、聚能切割、化学切割、电弧切割以及激光切割;对比机械切割、磨料射流切割以及特种切割方式的技术发展现状和趋势,分析上述切割方式的工程应用及优缺点;在此基础上,提出面向高效套管切割工程需求的主要切割技术及工具。结合目前切割技术及工具的发展现状,对未来井下管柱切割技术给出优化割刀性能、加强磨料射流切割的控制、研制新型切割工具及切割工具智能化等建议。

关键词：井下工具切割技术机械切割磨料射流切割特种切割

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线上联合BOPPPS教学模式在肝胆外科临床教学中的探索

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继续医学教育 2024年第4期38卷 65-68页

作者：刘一鸣吴天柱蔡璨重庆医科大学附属第二医院肝胆外科重庆400010 重庆医科大学附属第二医院消化内科重庆400010

随着互联网技术的不断发展,传统线下教育事业在不同形势下诞生了不同的需求,受到了一定的冲击,线上教育逐渐成为主流的教学方式。但单纯的线上教学并不能完全满足医学生临床实践的需求。在新形势下选择合适的教学模式才能促进学生适应... 详细信息

随着互联网技术的不断发展,传统线下教育事业在不同形势下诞生了不同的需求,受到了一定的冲击,线上教育逐渐成为主流的教学方式。但单纯的线上教学并不能完全满足医学生临床实践的需求。在新形势下选择合适的教学模式才能促进学生适应临床实践教学,提高临床实践的学习效率。BOPPPS教学模式以强调学生参与式互动和反馈为特点,将教学过程分为导入(bridge-in)、目标(objective)、前测(pre-assessment)、参与式学习(participatory)、后测(post-assessment)以及总结(summary)6个模块,帮助教师高效率、有质量地完成教学设计,提升学生的参与感。以“原发性肝恶性肿瘤”的教学为例,结合“超新学习通”线上学习平台将BOPPPS教学模式应用到课堂教学设计的过程中以期提高教学效果。

关键词： BOPPPS 线上教学肝胆外科教学模式临床教学临床实习

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Theoretical calculation of high-pressure CO_(2)jet in cases of composite rock-breaking based on span-wagner equation of state

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Journal of Hydrodynamics 2022年第5期34卷 948-964页

作者： Xian-peng Yang can cai Xiao-hua Chen Pei Zhang Xin Zeng Chi Peng Yingfang Zhou Oil and Gas Equipment Technology Sharing and Service Platform of Sichuan Province School of Mechanical EngineeringSouthwest Petroleum UniversityChengdu610500China School of Engineering University of AberdeenAberdeenUK Laboratory of High-pressure Jet Theory and Application Technology Southwest Petroleum UniversityChengdu610599China Key Laboratory of Groundwater Resources and Environment Ministry of EducationJilin UniversityChangchun130021China Southwest Pipeline Co. Ltd.National Pipe Network GroupChengdu610064China

Although several theoretical calculation methods for high-pressure jet are available,there is currently no theoretical model for the high-pressure CO_(2)jet based on the high-precision equation of state(EOS).To investigate the flow field of the high-pressure CO_(2)jet in cases of the composite rock-breaking under the high-pressure CO_(2)Jet and PDC cutter,a semi-analytical approach of the high-pressure CO_(2)jet is developed based on the Span-Wagner EOS and CO_(2)jet *** semi-analytical calculations and the physical property calculations under the action of the high-pressure CO_(2)jet are conducted with consideration of the jet pressure,the jet distance,the nozzle diameter and the jet *** results indicate that the distribution of the physical properties calculated by the semi-analytical approaches is similar to that obtained by experimental monitoring and numerical simulation,which indicates that the calculation method of the high-pressure CO_(2)jet presented in this paper is effective and *** properties of the CO_(2)jet obtained by the theoretical calculation see a significant difference between the initial region and the jet impact *** the temperature of 300 K,the increase of the initial pressure can effectively increase the impact force and the cooling ability of the *** proportion of the jet core lengths in the jet on the axis increases with the increase of the ratio of the nozzle diameter to the jet length,accompanied with the increase of the impact force of the *** increase of the jet angle can effectively increase the impacting force of the jet,but hampers the fluid *** study combines the theoretical calculation of the jet with the calculation of the physical properties of the high-pressure CO_(2),for comprehensively understanding the CO_(2)jet field in the composite rock-breaking under the action of the high-pressure CO_(2)jet and PDC *** theoretical calculation of the CO_(2)jet based on the high-precisio

关键词： CO_(2)jet hydraulic jet drill theoretical calculation equation of state(EOS) physical property

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Fracture propagation and induced strain response during supercritical CO_(2)jet fracturing

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Petroleum Science 2022年第4期19卷 1682-1699页

作者： can cai Bang-Run Li Yi-Yao Zhang Wen He Ying-Xin Yang Yong Kang Ji-Wei Wu School of Mechanical Engineering Southwest Petroleum UniversityChengdu610500SichuanP.R.China The State Key Laboratory of Oil&Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500SichuanP.R.China Shu'nan Gas-Mine of Southwest Oil and Gas Field Company Luzhou646000SichuanP.R.China Hubei Key Laboratory of Waterjet Theory and New Technology Wuhan UniversityWuhan430072HubeiP.R.China School of Engineering and Applied Sciences and Department of Physics Harvard UniversityCambridge02138United States School of Mechanical Engineering Yangtze UniversityJingzhou434023HubeiP.R.China

To investigate fracture generation and strain variation during SC-CO_(2)(supercritical carbon dioxide)jet fracturing,the model of induced strain is established and the experiments are comprehensively *** influence factors are comprehensively explored,such as jet pressure,ambient pressure,*** the increasing jet pressure,the fracture morphology changes from parallel cracks to oblique *** the mass loss of specimen and CO_(2) absorption increase significantly,and the growth rate and minimum value of strain also rise *** a high ambient pressure of 8.0 MPa,the main fractures mostly propagated from the surface to the bottom surface of the *** maximum strain and the stable duration under higher ambient pressure are 1.5 times and 10 times,respectively,of the case under the ambient pressure of 5.0 *** comparison shows that the optimal jet distance is 5-7 times the nozzle diameter,resulting in massive mass loss,large CO_(2)absorption,and peak ***,the nonlinear variation of strain curve during jet pressurization is related to the type of rock and ambient *** studies clearly show the relationship between the fracture morphology and induced strain,which are crucial for SC-CO_(2)fracturing in shale gas reservoirs.

关键词： Supercritical carbon dioxide fracturing Jet fracturing Fracture morphology Strain variation

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基于CHPS评价儿科人群使用万古霉素的安全性及风险因素

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中国现代药物应用 2024年第4期18卷 147-153页

作者：施丹妮蔡璨陈蔚达万隽黄志杰潘秀铭厦门大学附属妇女儿童医院科研创新中心 361003 厦门大学附属妇女儿童医院药学部 361003

目的基于中国医院药物警戒系统(CHPS)回顾性分析儿科人群使用万古霉素的安全性情况,并进一步探索不良反应发生的潜在危险因素,为临床安全使用万古霉素提供参考。方法利用CHPS,选取2013年7月~2023年6月在本院住院且需使用万古霉素抗感染... 详细信息

目的基于中国医院药物警戒系统(CHPS)回顾性分析儿科人群使用万古霉素的安全性情况,并进一步探索不良反应发生的潜在危险因素,为临床安全使用万古霉素提供参考。方法利用CHPS,选取2013年7月~2023年6月在本院住院且需使用万古霉素抗感染治疗的患儿作为研究对象,分析儿科人群使用万古霉的不良反应数据并做安全性评价,利用Logistic等统计学方法分析不良反应发生的危险因素。结果本研究纳入使用万古霉素的儿科人群980例次,常见的不良反应依次排序为γ-谷氨酰转肽酶升高(7.96%)、血红蛋白减少(6.43%)、嗜酸性粒细胞升高(5.61%)等;发现新的不良反应有低钾血症(0.82%)、尿酸增加(0.10%)和腹胀(0.29%);多因素分析中发现新生儿发生嗜酸性粒细胞升高的风险大于婴幼儿;女孩发生低钾血症的风险高于男孩;随着体重的升高。发生低钾血症的风险升高;合并苯巴比妥是γ-谷氨酰转肽酶升高的独立高危因素;合并左卡尼汀是天冬氨酸氨基转移酶升高和丙氨酸氨基转移酶升高的独立高危因素。结论万古霉素不良反应在儿科人群中发生率均较高。对于各方面机能不太健全的儿童,尤其是新生儿,应定期监护。监护的指标应包括γ-谷氨酰转肽酶、嗜酸性粒细胞、天冬氨酸氨基转移酶、丙氨酸氨基转移酶、血钾等。而在此后增设研究结果的危险因素至CHPS规则中,将利用触发器的功能,给予临床医生预警信息,以期减少不良反应的发生,提高儿科人群使用万古霉素的安全性。

关键词：万古霉素儿科人群安全性中国医院药物警戒系统

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Synergic catalysis of W and Ni originating from substitution of trivacant phosphotungstate for the selective oxidation of aniline to azoxybenzene

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Chinese Chemical Letters 2024年第2期35卷 558-563页

作者： Sheng cai Xiao-Yuan Wu Weiming Wu Sa-Sa Wang can-Zhong Lu CAS Key Laboratory of Design and Assembly of Functional Nanostructures and Fujian Provincial Key Laboratory of NanomaterialsFujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350117China Xiamen Institute of Rare Earth Materials Chinese Academy of SciencesXiamen 361021China University of Chinese Academy of Sciences Beijing 100049China

Partial substitution of polyoxometalate(POM)is an efficient route to modulate the catalytic property of maternal *** this work,a new Keggin type POM involving{Ni 6}cluster,{[Ni(H_(2) O)_(2)(Dach)_(2)][Ni(Dach)_(2)]_(2)}{[Ni_(6)Cl(μ-OH)_(3)(H_(2) O)(Dach)_(3)(WO_(4))(PW9 O_(3)_(4))][Ni_(6)(μ-OH)_(3)(H_(2) O)_(2)(Dach)_(3)(WO_(4))(PW9 O_(3)_(4))]}Cl·27H_(2) O,(1,Dach=1,2-diaminocyclohexane)was *** 1 shows excellent catalytic performance in the selective oxidation of aniline to azoxybenzene(AOB)in *** apparently different results from that with the matrix{PW 9 O_(3)_(4)}({PW9})suggest the successful regulation of the catalytic property of{PW9}by the introduction of the{Ni6}cluster into the *** experimental results indicate that the highlighted performance of 1 is contributed by the synergy of W and Ni sites,which are respectively responsible for the oxidation and condensation steps in the production of *** good selectivity to AOB is essentially attributed to the effective modulation of the reaction rates of oxidation and condensation steps by W and Ni sites,respectively.

关键词： Polyoxometalate {Ni6}cluster Modulated catalytic property Aniline oxidation Azoxybenzene

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Single-cell sequencing technology in diabetic wound healing:New insights into the progenitors-based repair strategies

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World Journal of Stem Cells 2024年第5期16卷 462-466页

作者： Zhen Xiang Rui-Peng cai Yang Xiao Yong-can Huang Shenzhen Engineering Laboratory of Orthopaedic Regenerative Technologies Department of Spine SurgeryPeking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina Department of Breast and Thyroid Surgery Peking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina

Diabetes mellitus(DM),an increasingly prevalent chronic metabolic disease,is characterised by prolonged hyperglycaemia,which leads to long-term health *** much effort has been put into understanding the pathogenesis of diabetic wounds,the underlying mechanisms remain *** advent of single-cell RNA sequencing(scRNAseq)has revolutionised biological research by enabling the identification of novel cell types,the discovery of cellular markers,the analysis of gene expression patterns and the prediction of develop-mental *** powerful tool allows for an in-depth exploration of pathogenesis at the cellular and molecular *** this editorial,we focus on progenitor-based repair strategies for diabetic wound healing as revealed by scRNAseq and highlight the biological behaviour of various healing-related cells and the alteration of signalling pathways in the process of diabetic wound *** could not only deepen our understanding of the complex biology of diabetic wounds but also identify and validate new targets for inter-vention,offering hope for improved patient outcomes in the management of this challenging complication of DM.

关键词： Single-cell sequencing Diabetic wound healing Cell subpopulations Heterogeneity Pathogenesis Progenitor cells

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