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Hydrogeological hazards and weather events:Triggering and evolution of shallow landslides

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International Soil and Water Conservation Research 2014年第2期2卷 23-29页

作者： salvatore Monteleone Maria Sabatino Dipartimento di Scienze della Terra e del Mare University of PalermoItaly

Landslides are the most intense and serious manifestations of the degradation of slopes and they are the main causes of geological hazard when they,directly or indirectly,involving towns and *** are a global environment problem;there are several examples that have produced untold damages and loss of human lives in many parts of the *** 1920 the landslides mobilization,as a result of a strong earthquake in China,in the province of Kansu,killed 200,000 people;in 1938 fast debris flow,triggered by heavy rainfalls in Japan,caused the death of 600 people;in 1963 in Italy the Vajont disaster caused the death of 1,899 people,as a result of a landslide localized in the underlying artificial *** the last years there have been many tragedies linked to intense rainfall events which have sparked many shallow landslides:1996 in Garfagnana,1998 in Sarno,2009 in the Ionic side of Messina,2011 in *** throw light on this problem,over the past decades,the assessment and mitigation of landslides hazard and the danger related to it,have become goals of paramount importance in territorial planning and,more generally,in its management and with it the safeguard of the historical and cultural heritage within *** occurrence of events which are considered exceptional thus implies a re-reading in terms of spatial planning to renovate the slopes and river-beds,as well as urban planning,infrastructural and socio-economic *** complex nature of these instability events that affect anthropized areas does not allow specific approaches for the defence of single good,but it finds a more effective solution based on the extensive knowledge of territory,perhaps at the scale of individual or several watersheds.

关键词： Geo-environmental hazard Hydrogeological instability Urban planning

A maintenance driven scheduling cockpit for integrated production and maintenance operation schedule

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Advances in Manufacturing 2022年第2期10卷 205-219页

作者： Mario Arena Valentina Di Pasquale Raffaele lannone salvatore Miranda Stefano Riemma Department of Industrial Engineering University of SalernoFiscianoSAItaly

The production and maintenance functions have objectives that are often in contrast and it is essential for management to ensure that their activities are carried out synergistically,to ensure the maximum efficiency of the production plant as well as the minimization of management *** current evolution of ICT technologies and maintenance strategies in the industrial field is making possible a greater integration between production and *** work addresses this challenge by combining theknowledge of the data collected from physical assets for predictive maintenance management with the possibility of dynamic simulate the future behaviour of the manufacturing system through a digital twin for optimal management of maintenance *** paper,indeed,presents a supporting digital cockpit for production and maintenance integrated *** proposes an innovative approach to manage health data from machines being in any production system and provides support to compare the information about their remaining useful life(RUL)with the respective production *** maintenancedriven schedulingcockpit(MDSC)offers,indeed,a supporting decision tool for the maintenance strategy to be implemented that can help production and maintenance managers in the optimal scheduling of preventive maintenance interventions based on RUL *** simulation is performed by varying the production schedule with the maintenance tasks involvement;opportune decisions are taken evaluating the total costs related to the simulated strategy and the impact on the production schedule.

关键词： Industry 4.0-Maintenance task Production schedule Predictive maintenance Integrated plan

A rare case of acute compartment syndrome after saphenectomy

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World Journal of Clinical Cases 2013年第2期1卷 84-86页

作者： Marco Milone Piero Venetucci salvatore Iervolino Caterina Taffuri Giuseppe salvatore Francesco Milone Department of Advanced Biomedical Science University "Federico Ⅱ" of Naples

Saphenectomy is one of the most validated criteria to treat varicose veins of the lower legs. Although many complications were well described, little is known about compartment syndrome due to muscle ischemia caused by constrictive bandages applied after stripping of varicose veins. We presented a case of successful conservative treatment of compartment syndrome after saphenectomy. Rehabilitation was found effective in improving fatigue, stiffness and tenderness showing the effectiveness of the combined conservative-rehabilitative treatment. However conservative treatment could not be considered the treatment of choice in daily practice. A severity score assessment of compartment syndrome should be useful to assess to which patients is allowed to not perform fasciotomy.

关键词： Compartment Saphenectomy Varicose veins Muscle ischemia Rehabilitation

Sediment provenance of a carbonate bioclastic pocket beach—Le Dune(Ionian Sea,South Italy)

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Journal of Palaeogeography 2022年第2期11卷 238-255页

作者： Isabella Lapietra Stefania Nunzia Lisco salvatore Milli Beatrice Rossini Massimo Moretti Dipartimento di Scienze Della Terra e Geoambientali Universit a Degli Studi di BariVia Orabona 470124 BariItaly Dipartimento di Scienze Della Terra SapienzaUniversit a di RomaPiazzale Aldo Moro 500185 RomaItaly

This study focuses on the analysis of a carbonate bioclastic pocket beach located along a coastal sector of the Apulia Ionian Sea,Le Dune beach,South *** beach develops for about 800 m and it is exposed to the south-westerly and southerly *** sediments range from very coarse to medium-fine sands and they are mainly composed of bioclasts(more than 90%)which include molluscs,foraminifers,echinoderms,algae branched,bryozoans,spicules of sponges and *** study area is one part of a marine protected reserve characterised by 15 different habitats of the typical Mediterranean submerged populations and the presence of Posidonia oceanica *** aim of our research is to highlight the correlation between physical and biological processes influencing Le Dune beach dynamics and its sediment provenance by analysing the textural and compositional characteristics of beach sands,which is fundamental for pocket beach *** beach sand analysis,deriving from textural,compositional and bioclast investigations,underlines that one of the main indicators of the beach dynamics is the bioclast component,which provides relevant information about sand provenance and sediment *** beach constitutes a semi-close system only nourished by the shells of organisms and by the erosion of headlands and dunes without important sediment interchange with adjacent littoral sectors.

关键词： Pocket beach Carbonate sediment supply Bioclast distribution Coastal dynamics

Hollow micro- and nano-particles by gas foaming

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Nano Research 2014年第7期7卷 1018-1026页

作者： Silvia Orsi Ernesto Di Maio salvatore lannace Paolo A. Netti Center for Advanced Biomaterials for Health Care Istituto Italiano di Tecnologia (IIT@CRIB) Largo Barsanti e Matteucci 50 Napoli 80125 Italy Dipartimento di Ingegneria Chimica dei Materiali e della Produzione Industfiale and Interdisciplinary Research Centre on Biomaterials (CRIB) Universita degli Studi di Napoli Federico II P.le Tecchio 80 Napoli 80125 Italy Institute for Polymers Composites and Biomaterials Consiglio Nazionale delle Ricerche P.le E. Fermi 1 Portici (Na) 80055 Italy

This paper presents the results of a first successful attempt to produce hollow micro- and nano-particles of a large variety of materials, dimensions, shapes and hollow attributes by using an environmentally friendly and cheap technology, common in polymer processing and known as gas foaming. The central role played by ad hoc polymeric hollow micro- and nano-particles in a variety of emerging applications such as drug delivery, medical imaging, advanced materials, as well as in fundamental studies in nanotechnology highlights the wide relevance of the proposed method. Our key contribution to overcome the physical lower bound in the micro- and nano-scale gas foaming was to embed, prior to foaming, bulk micro- and nano-particles in a removable and deformable barrier film, whose role is to prevent the loss of the blowing agent, which is otherwise too fast to allow bubble formation. Furthermore, the barrier film allows for non-isotropic deformation of the particle and/or of the hollow, affording non-spherical hollow particles. In comparison with available methods to produce hollow micro- and nano-particles, our method is versatile since it offers independent control over the dimensions, material and shape of the particles, and the number, shape and open/closed features of the hollows. We have gas- foamed polystyrene and poly-（lactic-co-glycolic） acid particles 200 ~m to 200 nm in size, spherical, ellipsoidal and discoidal in shape, obtaining open or closed, single or multiple, variable in size hollows.

关键词： hollow nanoparticles microparticles gas foaming

Deep Learning and Time Series-to-Image Encoding for Financial Forecasting

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IEEE/CAA Journal of Automatica Sinica 2020年第3期7卷 683-692页

作者： Silvio Barra salvatore Mario Carta Andrea Corriga Alessandro Sebastian Podda Diego Reforgiato Recupero Department of Mathematics and Computer Science University of CagliariCagliari 09121Italy

In the last decade,market financial forecasting has attracted high interests amongst the researchers in pattern ***,the data used for analysing the market,and then gamble on its future trend,are provided as time series;this aspect,along with the high fluctuation of this kind of data,cuts out the use of very efficient classification tools,very popular in the state of the art,like the well known convolutional neural networks(CNNs)models such as Inception,Res Net,Alex Net,and so *** forces the researchers to train new tools from *** operations could be very time *** paper exploits an ensemble of CNNs,trained over Gramian angular fields(GAF)images,generated from time series related to the Standard&Poor's 500 index future;the aim is the prediction of the future trend of the ***.A multi-resolution imaging approach is used to feed each CNN,enabling the analysis of different time intervals for a single observation.A simple trading system based on the ensemble forecaster is used to evaluate the quality of the proposed *** method outperforms the buyand-hold(B&H)strategy in a time frame where the latter provides excellent *** quantitative and qualitative results are provided.

关键词： Convolutional neural networks(CNNs) ensemble of CNNs financial forecasting Gramian angular fields(GAF)imaging

Screening for pancreatic cancer-a compelling challenge

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Hepatobiliary Surgery and Nutrition 2021年第2期10卷 264-266页

作者： Gabriele Capurso salvatore Paiella Massimo Falconi Pancreato-Biliary Endoscopy and Endosonography Division Pancreas Translational&Clinical Research CenterSan Raffaele Scientific Institute IRCCSMilanItaly General and Pancreatic Surgery Unit Pancreas InstituteUniversity of VeronaVeronaItaly Pancreatic Surgery Unit Pancreas Translational&Clinical Research CenterSan Raffaele Scientific Institute IRCCSUniversitàVita-SaluteMilanItaly

Efficacy of pancreatic cancer surveillance programs The publication of the American Gastroenterology Association(AGA)Clinical Practice Update on Pancreas Cancer Screening in High-Risk Individuals(HRIs)underlines the increasing attention for this topic(1).Secondary prevention(surveillance)for pancreatic ductal adenocarcinoma(PDAC),however,remains a challenge with many unsolved questions(Table 1).

关键词： prevention cancer Cancer

Hepatocellular carcinoma: Will novel targeted drugs really impact the next future?

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World Journal of Gastroenterology 2016年第27期22卷 6114-6126页

作者： Liliana Montella Giovannella Palmieri Raffaele Addeo salvatore Del Prete Medical Oncology Unit "San Giovanni di Dio" Hospital Oncology Unit Department of Clinical Medicine and Surgery "Federico II" University of Naples

Cancer treatment has been revolutionized by the advent of new molecular targeted and immunotherapeutic agents. Identification of the role of tumor angiogenesis changed the understanding of many tumors. After the unsuccessful results with chemotherapy, sorafenib, by interfering with angiogenic pathways, has become pivotal in the treatment of hepatocellular carcinoma. Sorafenib is the only systemic treatment to show a modest but statistically significant survival benefit. All novel drugs and strategies for treatment of advanced hepatocellular carcinoma must be compared with the results obtained with sorafenib, but no new drug or drug combination has yet achieved better results. In our opinion, the efforts to impact the natural history of the disease will be directed not only to drug development but also to understanding the underlying liver disease(usually hepatitis B virus- or hepatitis C virus-related) and to interrupting the progression of cirrhosis. It will be important to define the role and amount of mutations in the complex pathogenesis of hepatocellular carcinoma and to better integrate locoregional and systemic therapies. It will be important also to optimize the therapeutic strategies with existing chemotherapeutic drugs and new targeted agents.

关键词： Hepatocellular carcinoma Targeted therapy Pathway Angiogenesis Sorafenib

Bacterial Infections in Cirrhosis

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Infectious Microbes & Diseases 2021年第3期3卷 117-124页

作者： Marta Tonon Paolo Angeli salvatore Piano State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseaseThe First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiangChina

Bacterial infections are the most common trigger of acute decompensation of *** occurrence of infections in cirrhosis is associated with the development of organ dysfunctions,failures,and acute on chronic liver *** combination of infections and organ dysfunction/acute on chronic liver failure dramatically increases the mortality risk in these *** in cirrhosis are a big challenge for clinicians,since the mortality from sepsis is increasing in these patients *** rapid and progressive spread of multiresistant bacteria has been blamed for the increased mortality *** studies have shown that early diagnosis and appropriate administration of antibiotic treatment are crucial for improving prognosis in these ***,the prevention and treatment of acute kidney injury and organ failures are fundamental parts of management of infections in *** we provided a concise and updated review of the literature on bacterial infections in patients with cirrhosis.

关键词： liver cirrhosis liver transplantation multidrug resistant sepsis septic shock