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Inter- and intraobserver agreement in computed tomography enterography in inflammatory bowel disease

World Journal of Gastroenterology 2016年第45期22卷 10002-10008页

作者： Natally Horvat camila Carlos Tavares Adriana Ribas Andrade Julia Campos Sim?es Cabral Hilton Muniz Le?o Filho Angela Hissae Motoyama Caiado Serli Kiyomi Nakao Ueda André Zonetti de Arruda Leite Aytan Miranda Sipahi Manoel de Souza Rocha Radiology Department Hospital das Clínicas da Faculdade de Medicina da Universidade de S?o Paulo Gastroenterology Department Lim 07 Hospital da Clínicas da Faculdade de Medicina da Universidade de S?o Paulo

AIM To evaluate intra- and interobserver agreement in imaging features in inflammatory bowel disease and comparison with fecal calprotectin(FC) *** Our institutional computed tomography enterography(CTE) database was retrospectively queried to identify patients who underwent CTE from January 2014 to June 2015. Patient inclusion criteria were confirmed inflammatory bowel disease(IBD) and FC collected 1 pattern, or normal); and signs of active disease(present or absent). In 42 of 44 patients evaluated, routine CTE reports were made by one of the readers who reevaluated the CTEs ≥ 6 mo later, to determine the intraobserver agreement. FC was considered a sign of disease activity when it was higher than 250 μg/*** Forty-four patients with IBD(38 with Crohn's disease and 6 with ulcerative colitis) were included. There was a moderate interobserver agreement regarding localization of IBD(k = 0.540), type of disease(k = 0.410) and the presence of active signs in CTE(k = 0.419). There was almost perfect intraobserver agreement regarding localization, type and signs of active disease in IBD. The k values were 0.902, 0.937 and 0.830, respectively. After a consensus between both radiologists regarding inflammatory activity in CTE, we found that 24(85.7%) of 28 patients who were classified with active disease had elevated FC, and six(37.5%) of 16 patients without inflammatory activity in CTE had elevated FC(P = 0.003). The correlation between elevated FC and the presence of active disease in CTE was significant(k = 0.495, P = 0.001).CONCLUSION We found almost perfect intraobserver and moderate interobserve

关键词： Crohn’s disease Ulcerative colitis Computed tomography Fecal calprotectin Inflammatory bowel disease activity

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A simple and easy method to measure ammonia volatilization:Accuracy under field conditions

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Pedosphere 2021年第2期31卷 255-264页

作者： Márcio R.MARTINS Leonardo F.SARKIS Roni F.GUARESCHI camila A.SANTOS Selenobaldo A.C.SANT’ANNA Mohammad ZAMAN Claudia P.JANTALIA Bruno J.R.ALVES Robert M.BODDEY Ednaldo S.ARAÚJO Segundo URQUIAGA Embrapa Agrobiology Rod.BR 465km 7Seropédica RJ CEP 23891-000(Brazil) Agroscope Research Division Agroecology and EnvironmentClimate and Agriculture GroupReckenholzstrasse 191Zurich 8046(Switzerland) Federal Rural University of Rio de Janeiro(UFRRJ) Rod.BR 465km 7Seropédica RJ CEP 23891-000(Brazil) Soil and Water Management&Crop Nutrition Joint FAO/IAEA Division of Nuclear Techniques in Food&AgricultureP.O.Box 100Vienna A-1400(Austria)

Field studies on soil ammonia(NH_(3))volatilization are restricted in many countries owing to the high costs commonly demanded for accurate *** assessed the accuracy of a simple,open chamber design to capture NH_(3)under field conditions,as affected by different chamber placement ***-15 N was surface applied to lysimeters installed in the spaces between maize *** chambers made from plastic bottles were installed on each lysimeter with variations in i)N rates(3,8,13,and 18 g m^(-2)),ii)the height of the chamber above the soil surface(0,5,and 10 mm),and iii)chamber relocation(static ***).Reference lysimeters without chambers were used to measure NH_(3)losses by^(15)*** of NH_(3)-N accounted for more than 50%of the applied *** of the chambers had no impact on their NH_(3)-trapping efficiencies,proving to be an unnecessary *** in the height of the chambers above the soil surface affected the capture of NH_(3),but the results still maintained high linearity with the NH_(3)losses quantified by the reference method(R^(2)>0.98).When the same placement scheme used in the introductory study describing the chamber was utilized(static and touching the soil surface),we found a trapping efficiency of 60%,which was very similar to that(57%)obtained in the previous *** results show that this simple,open chamber design can be used with satisfactory accuracy under field conditions,provided that simple,standardized procedures are warranted.

关键词： ammonia collector chamber method field sampler gas emission low-cost chamber nitrogen cycling

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Polyphenols in Fruits and Vegetables and Its Effect on Human Health

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Food and Nutrition Sciences 2014年第11期5卷 1065-1082页

作者： Giuseppina Pace Pereira Lima Fabio Vianello camila Renata Corrêa Renê Arnoux da Silva Campos Milena Galhardo Borguini Department of Chemistry and Biochemistry Sao Paulo State UniversityUNESPBotucatuSao PauloBrazil Department of Comparative Biomedicine and Food Science University of PadovaPadovaItalia Department of Internal Medicine Botucatu Medical SchoolSao Paulo State UniversityUNESPBotucatuSao PauloBrazil

Polyphenols represent a group of chemical substances common in plants, structurally characterized by the presence of one or more phenol units. Polyphenols are the most abundant antioxidants in human diets and the largest and best studied class of polyphenols is flavonoids, which include several thousand compounds. Numerous studies confirm that they exert a protective action on human health and are key components of a healthy and balanced diet. Epidemiological studies correlate flavonoid intake with a reduced incidence of chronic diseases, such as cardiovascular disease, diabetes and cancer. The involvement of reactive oxygen species (ROS) in the etiology of these degenerative conditions has suggested that phytochemicals showing antioxidant activity may contribute to the prevention of these pathologies. The present review deals with phenolic compounds in plants and reports on recent studies. Moreover, the present work includes information on the relationships between the consumption of these compounds, via feeding, and risk of disease occurrence, i.e. the effect on human health. Results obtained on herbs, essential oils, from plants grown in tropical, subtropical and temperate regions, were also reported.

关键词： Fruits Vegetables Consume Effect on Human Phenolic Content Thermal Processing Absorption

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Supercritical extraction to obtain vetiver （Vetiveria zizanioides L. Nash） extracts from roots cultivated hydroponically

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Journal of Agricultural Science and Technology 2008年第10期2卷 44-50页

作者： camila G.Pereira Isabela P.Gualtieri Nilson B.Maia M.Angela A.Meireles Department of Chemical Engineering-UFRN Natal RN 59072-970 Brazil LASEFI/DEA/FEA（College of Food Eng）/UNICAMP（University of Campinas） CampinasSao PauloCx.P.612113083-970Brazil LAC（Agronomic Institute of Campinas） CampinasSao PauloCx.P.2813001-970Brazil

We determined the global yield and composition of extracts from vetiver roots cultivated hydroponically. We extracted roots of two varieties collected at different times after planting. The extracts were obtained by supercritical fluid extraction （SFE）; we also estimated manufacturing costs. Constituents were quantified by gas-chromatography/time ionization detection （GC-FID）. Results demonstrated the efficacy of a hydroponic system in producing vctiver with a high root extract content. The largest yield was obtained from roots collected on days 132 and 92 after planting from varieties National （1.41%） and Bourbon （1.28%）, respectively. The major compounds present in the extract were khusimoi, isovalencenol, alpha-vetivone and beta-vetivone. To determine the economic viability of producing these extracts, manufacturing costs were estimated using a simplified methodology. The manufacturing costs were US$ 22.26/kg and US$ 24.26/kg for varieties national and Bourbon, respectively.

关键词： manufacturing cost hydroponics supercriticalfluid extraction Vetiveria zizanioides

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Investigations on the Thermodynamic Stability and Availability of Nutrients for Plants by Humic Substances Extracted from Peat Samples

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Journal of Environmental Science and Engineering(A) 2015年第7期4卷 367-377页

作者： camila De Almeida Melo Lilian Karla De Oliveira Bruno Barboza Cunha Leonardo Femandes Fraceto Andre Henrique Rosa Department of Environmental Engineering Sao Paulo State University (UNESP) Sorocaba 18087-180 Sao Paulo State Brazil

This work evaluated the complexation capacity, exchange constants and availability of micronutrients for plants and humic substances extracted from peat samples. Samples of humic substances extracted from two tropical peats （HS-P1 and HS-P2） were enriched with the micronutrients Cu（II）, Co（II）, Fe（II）, Mn（II）, Ni（II） and Zn（II） and the parameters for formation of the complexes （HS-N） were evaluated at different pH. The Scatchard model was used to calculate the maximum complexation capacity and the nutrient availability was studied using exchange capacity experiments based on ultrafiltration procedure. The optimum pH for complexation was 4.5 and the order of affinity was： Fe（II）〉 Cu（II）〉 Co（II）〉 Mn（II） = Ni（II）〉 Zn（II）. The maximum complexation capacity reached 56.8 mg·g-1 Fe of HS-P1 （the highest） and 1.7 mg.g1 Zn of HS-P2 （the slightest）. The exchange experiments showed that HS-P-Fe complexes were formed preferentially. The least stable complex was formed with Zn, which was therefore, more easily available. The results contribute to understand the behavior and availability of some nutrients in soils.

关键词： Peat humic substances complexation nutrient availability exchange capacity soil

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墨西哥卡洛塔酒店

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设计 2017年第10期30卷 30-31页

作者： jacob camila cossío(图)

这个建筑设计项目是城市考古项目的起点。建筑来自一处逐渐荒废的场地，原来是亚马逊花园酒店。设计师了解到当时这个院子作为城市绿洲，景象十分奢华。院中看得到多达17种装饰物、人工草坪和那些在泳池中享受日光浴的男女。然而随着时... 详细信息

这个建筑设计项目是城市考古项目的起点。建筑来自一处逐渐荒废的场地，原来是亚马逊花园酒店。设计师了解到当时这个院子作为城市绿洲，景象十分奢华。院中看得到多达17种装饰物、人工草坪和那些在泳池中享受日光浴的男女。然而随着时间流逝，酒店只剩下原有的带连廊的结构，和数不清的表皮、聚合物、台阶和天花板。

关键词：花园酒店墨西哥城市绿洲设计项目人工草坪塔亚马逊设计师

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Comparison of morphological and functional outcomes of mouse sciatic nerve repair with three biodegradable polymer conduits containing poly (lactic acid)

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Neural Regeneration Research 2018年第10期13卷 1811-1819页

作者： Fernanda Marques Pestana Rui C.C.Domingues Júlia Teixeira Oliveira Daniela F.P.A.Durco camila Oliveira Goulart Henrique Rocha Mendonca Anne Caroline Rodrigues dos Santos Natália Tavares de Campos Beatriz Theodoro da Silva Cristina Cardoso Pereira Cristiano Piacsek Borges Ana Maria Blanco Martinez Pós Graduacao em Ciências Morfológicas Instituto de Ciências Biomédicas-UFRJRio de Janeiro RJ Brazil Anatomia Patológica-Faculdade de Medicina-HUCFF-UFRJ Rio de Janeiro RJ Brazil Laboratório de Neurodegeneracao e Reparo-Faculdade de Medicina-HUCFF-UFRJ Rio de Janeiro RJ Brazil Programa de Eng. Química COPPE-UFRJRio de Janeiro Brazil Polo Universitário de Macaé Laboratório Integrado de Produtos Bioativos e BiociênciasMacaê UFRJ Brazil

Poly（lactic acid）（PLA）-containing nerve guidance conduits（NGCs） are currently being investigated for nerve repair as an alternative to autograft, which leads to permanent functional impairment in the territory innervated by the removed nerve. Combination of polymers modifies the physical properties of the conduits, altering their nerve-guidance properties. Conduits made from PLA-only or combined with other polymers have been used successfully for nerve repair, but their efficiency has not been compared. We compared the morphological and functional outcomes of peripheral nerve repair by using NGCs made of poly（lactic acid） and combined or not with polycaprolactone（PLA/PCL） or polyvinylpyrrolidone（PLA/PVP）. To assess the functional recovery, we employed a mechanical hyperalgesia analysis, sciatic functional index（SFI）, and electroneuromyography. The mechanical hyperalgesia analysis showed that the PLA group improved more rapidly than the PLA/PVP and PLA/PCL groups; similarly, in the electroneuromyography assay, the PLA group exhibited higher amplitude than the PLA/PCL and PLA/PVP groups. However, the SFI improvement rates did not differ among the groups. Morphologically, the PLA group showed more vascularization, while the nerve fiber regeneration did not differ among the groups. In conclusion, the PLA-only conduits were superior to the other NGCs tested for nerve repair.

关键词： sciatic nerve tubulization biodegradable conduit poly(lactic acid) regeneration

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Musculoskeletal Pain in Medical Students Subject to Remote Teaching during the COVID-19 Pandemic

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Journal of Biosciences and Medicines 2021年第8期9卷 92-19页

作者： Isabela de Paiva Gomes Vivian Mitleton Luiz Gustavo Benedetti Fiorin camila dos Santos Leite Oscar César Pires Medicine Department Taubaté University Taubaté Brazil

Musculoskeletal pain is a consequence of repetitive strain, overuse, and work-related musculoskeletal disorders. In 2020, due to the new coronavirus pandemic, social isolation started, and so did online classes in a remote study strategy to replace classroom-based study routines. Thus, students adopted a different physical posture from the usual one for a longer time than usual, representing a possible risk factor for musculoskeletal pain. In this sense, this research aimed to identify the occurrence of musculoskeletal pain in medical students subject to distance learning during the COVID-19 pandemic. A cross-sectional, descriptive and exploratory study was applied through an online questionnaire, using the Google Forms application, to 154 students from the first to the fourth year of the medical course at a university in the countryside of the state of S?o Paulo. Among the participants, 99 (64.3%) were female, and 54 (35.7%) were male individuals with ages ranging from 18 and 34. In regards to the daily study time in sitting position, 83 (55.0%) reported staying more than 4 hours, 39 (25.8%) between 2 and 4 hours, and 29 (19.2%) less than 2 hours still. As for musculoskeletal pain before the pandemic;98 (63.6%) reported not feeling it, while 56 (36.4%) reported being affected by this type of pain. However, after the pandemic, 51 respondents (33.1%) continued not to feel anything, whereas 103 (66.9%) kept on having some type of musculoskeletal pain. The results obtained suggest an increase in musculoskeletal pain during the pandemic however other studies may confirm these findings.

关键词： Musculoskeletal Pain Medical Students Remote Teaching COVID-19 Pandemic

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Optimizing the use of open chambers to measure ammonia volatilization in field plots amended with urea

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Pedosphere 2021年第2期31卷 243-254页

作者： Márcio R.MARTINS Leonardo F.SARKIS Selenobaldo A.C.SANT’ANNA camila A.SANTOS Karla E.ARAUJO Ricardo C.SANTOS Ednaldo S.ARAÚJO Bruno J.R.ALVES Claudia P.JANTALIA Robert M.BODDEY Mohammad ZAMAN Segundo URQUIAGA Embrapa Agrobiology Rod.BR 465km 7Seropédica RJ CEP 23891-000(Brazil) Federal Rural University of Rio de Janeiro(UFRRJ) Rod.BR 465km 7Seropédica RJ CEP 23891-000(Brazil) Agroscope Research Division Agroecology and EnvironmentClimate and Agriculture GroupReckenholzstrasse 191Zurich 8046(Switzerland) Soil and Water Management&Crop Nutrition Joint FAO/IAEA Division of Nuclear Techniques in Food&AgricultureP.O.Box 100Vienna A-1400(Austria)

Measuring ammonia(NH_(3))volatilization from urea-fertilized soils is crucial for evaluation of practices that reduce gaseous nitrogen(N)losses in *** small area of chambers used for NH_(3)volatilization measurements compared with the size of field plots may cause significant errors if inadequate sampling strategies are *** aims were:i)to investigate the effect of using multiple open chambers on the variability in the measurement of NH_(3)volatilization in urea-amended field plots and ii)to define the critical period of NH_(3)-N losses during which the concentration of sampling effort is capable of reducing *** use of only one chamber covering 0.015%of the plot(51.84 m^(2))generates a value of NH_(3)-N loss within an expected margin of error of 30%around the true *** reduce the error margin by half(15%),3–7 chambers were required with a mean of 5 chambers per *** the sampling efforts in the first two weeks after urea application,which is usually the most critical period of N losses and associated errors,represents an efficient strategy to lessen uncertainty in the measurements of NH_(3)*** strategy enhances the power of detection of NH_(3)-N loss abatement in field experiments using chambers.

关键词： chamber method experimental error gas emission low-cost chamber nitrogen cycling nitrogen loss soil variability

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Avocado and Cardiovascular Health

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Open Journal of Endocrine and Metabolic Diseases 2015年第7期5卷 77-83页

作者： camila Weschenfelder Júlia Lorenzon dos Santos Priscilla Azambuja Lopes de Souza Viviane Paiva de Campos Aline Marcadenti Postgraduate Studies Program in Cardiology Instituto de Cardiologia/Fundacao Universitária de Cardiologia do Rio Grande do Sul (IC/FUC) Porto Alegre Brazil Department of Nutrition Federal University of Health Sciences of Porto Alegre (UFCSPA) Porto Alegre Brazil

Avocado is a fruit which had a caloric density of 1.7 kcal per gram and a half unit (~70 g) is composed by 114 kcal, 4.6 g of fibers, 345 mg of potassium, 19.5 mg of magnesium, 1.3 mg of vitamin E and 57 mg of phytosterols. Approximately 75% of fiber’s avocado contents are considered insoluble and 25% are soluble. The avocado contains lipids that consist of 71% from monounsaturated fatty acids (MUFA), 13% from polyunsaturated (PUFA) and 16% from saturated fatty acids (SFA). Recent researches have shown that avocado may improve hypercholesterolemia and may be useful in the treatment of hypertension and type 2 diabetes mellitus (T2DM). This way, avocado plays an important role in the cardiovascular health. This review summarizes the potential benefits of avocado consumption in the prevention of cardiovascular risk factors and metabolic diseases.

关键词： Persea Diabetes Mellitus Type 2 Dyslipidemias Nutritional Status Blood Pressure

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