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从平民村到工人新村上海公营住宅延续的文明教化使命,1927——1951年

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时代建筑 2017年第2期60卷 30-35页

作者：梁智勇香港大学建筑学院园境建筑学部

文章旨在探讨1949年前后关于上海公营住宅的论述与实践的延续性,并考察了民国时期的"平民村"与社会主义时期的"工人新村"的三个重要方面。第一,"新村"自20世纪20年代开始被赋予不同的含义。许多城市改良方案均以新村之名,新村成为住宅... 详细信息

文章旨在探讨1949年前后关于上海公营住宅的论述与实践的延续性,并考察了民国时期的"平民村"与社会主义时期的"工人新村"的三个重要方面。第一,"新村"自20世纪20年代开始被赋予不同的含义。许多城市改良方案均以新村之名,新村成为住宅改良的重要场所。第二,文章阐释了民国时期对住宅改良与城市管理在建设新国家时的作用的不同思考。第三,文章分析了不同的参与者,例如政府和建筑规划专家,在关于公营住宅的实践与论述中所发挥的作用。通过对平民村和工人新村的比较,文章指出,尽管国民政府与社会主义政府在意识形态与城市政策上存在分歧,但是其公营住宅建设皆延续了始于20世纪初期的住宅改良的文明教化使命以及"科学化"的综合规划。

关键词：工人新村民国公营住宅文明教化综合规划上海

Cultivating stem cells for treating amyotrophic lateral sclerosis

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World Journal of stem Cells 2012年第12期4卷 117-119页

作者： shengwen calvin Li hong Zhen Yin William G Loudon John h Weiss ChOC Children's hospital University of California Irvine Department of Neurology University of California IrvineOrange Department of Neurology University of California Irvine Department of Neurological surgery University of California IrvineOrange

This editorial addresses the current challenges and future directions in the use of stem cells as an approach for treating amyotrophic lateral sclerosis.A wide variety of literature has been reviewed to enlighten the reader on the many facets of stem cell research that are important to consider before using them for a cell based therapy.

关键词： stem cell therapy Amyotrophic lateral sclerosis

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采用共晶方法提高白黎芦醇溶解度与可压性

采用共晶方法提高白黎芦醇溶解度与可压性

成为“完整的人”——20世纪初期上海基督教青年会的“模范村”探索

中国晶体学会第六届学术年会暨会员代表大会——第六届全国晶型药物研发技术学术研讨会

作者：周政政李婉莹 Wei-Jhe sun 鲁统部 henry h.Y.Tong Changquan calvin sun 郑颖南方医科大学公共卫生学院卫生检验检疫系广东省热带病研究重点实验室 state Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of Macau Department of Pharmaceutics University of Minnesota 中山大学化学化工学院中山大学药学院 school of health sciences Macao Polytechnic Institute

固体药物的理化性质特别是水溶性、机械性质等是影响成药性的关键因素,因此改善药物的理化性质对于进一步的新药开发具有十分重要的意义。药物共晶通过选择合适的共晶试剂与药物分子作用形成超分子体系可有效改善其理化性质。前期研究发... 详细信息

固体药物的理化性质特别是水溶性、机械性质等是影响成药性的关键因素,因此改善药物的理化性质对于进一步的新药开发具有十分重要的意义。药物共晶通过选择合适的共晶试剂与药物分子作用形成超分子体系可有效改善其理化性质。前期研究发现BCsⅡ类天然产物白黎芦醇水溶性低(0.03g.L)且可压性差,不易成型,因此采用共晶手段来改善其溶解度与机械性质等。通过综合PXRD、DsC、TG、ssNMR、FTIR等方法进行分析发现白黎芦醇可与4-aminobenzamide、isoniazid形成化学计量比例为1:1的新药物共晶体系,其中REs-IsN(1:1)共晶可形成稳定的基于热力学数据的二元相图。与白黎芦醇原料药相比,新形成的共晶体系在溶解度、可压性等理化性质方面具有显著提高,且溶解度具有ph依赖性,共晶在高湿环境中依然表现出良好的稳定性。研究结果可为白黎芦醇天然产物的进一步开发提供合适的候选固体形态,具有重要的科学意义与应用价值。

关键词：白黎芦醇共晶溶解度可压性机械性质

来源： cnki会议评论

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新建筑 2018年第5期 34-37页

作者：梁智勇香港大学香港999077

"模范村"是一种出现在20世纪初期的工人阶级集体居住模式。文章以上海基督教青年会(YMCA)浦东劳工模范村——上海20年代开拓性的劳工住房项目为例,探讨青年会对理想"劳工生活"的不同想象与如何塑造"模范村"的实践。"模范村"试图通过对... 详细信息

"模范村"是一种出现在20世纪初期的工人阶级集体居住模式。文章以上海基督教青年会(YMCA)浦东劳工模范村——上海20年代开拓性的劳工住房项目为例,探讨青年会对理想"劳工生活"的不同想象与如何塑造"模范村"的实践。"模范村"试图通过对工人阶级住宅与教育的改良,调整和稳固资本主义经济下的劳资关系。研究认为,浦东劳工模范村中健康居住环境与"完全的人格"教育的结合是年轻专才与慈善家对中国急速资本主义城市化下对理想劳工关系的共同探索成果。他们相信只有工人阶级拥有经济与精神上的独立自主,社会发展才能惠及大众,而提供设计完善的居所并结合完整的教育是达致这一目标最有效途径。

关键词：基督教青年会模范村劳资关系工人住宅集合居住上海民国时期

Laser wakefield accelerator modelling with variational neural networks

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high Power Laser science and Engineering 2023年第1期11卷 67-74页

作者： M.J.V.streeter C.Colgan C.C.Cobo C.Arran E.E.Los R.Watt N.Bourgeois L.calvin J.Carderelli N.Cavanagh s.J.D.Dann R.Fitzgarrald E.Gerstmayr A.s.Joglekar B.Kettle P.Mckenna C.D.Murphy Z.Najmudin P.Parsons Q.Qian P.P.Rajeev C.P.Ridgers D.R.symes A.G.R.Thomas G.sarri s.P.D.Mangles school of Mathematics and Physics Queen’s University BelfastBelfastUK The John Adams Institute for Accelerator science Imperial College LondonLondonUK York Plasma Institute School of PhysicsEngineering and TechnologyUniversity of YorkYorkUK Central Laser Facility STFC Rutherford Appleton LaboratoryDidcotUK Gérard Mourou Center for Ultrafast Optical science University of MichiganAnn ArborUSA Ergodic LLC San FranciscoUSA Department of Physics SUPAUniversity of StrathclydeGlasgowUK

A machine learning model was created to predict the electron spectrum generated by a GeV-class laser wakefield *** model was constructed from variational convolutional neural networks,which mapped the results of secondary laser and plasma diagnostics to the generated electron *** ensemble of trained networks was used to predict the electron spectrum and to provide an estimation of the uncertainty of that *** is anticipated that this approach will be useful for inferring the electron spectrum prior to undergoing any process that can alter or destroy the *** addition,the model provides insight into the scaling of electron beam properties due to stochastic fluctuations in the laser energy and plasma electron density.

关键词： laser plasma interactions particle acceleration neural networks machine learning

Dental trauma in endoscopy:A systematic review and experience of a tertiary endoscopy centre

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World Journal of Gastrointestinal Endoscopy 2023年第8期15卷 518-527页

作者： Chelsea Qiu Lin Tan Gabrielle Yi Wen Loh Tay Wei Rong Benjamin calvin Jianyi Koh John shao Rong Mok Juanda Leo hartono Kai Ting Cheryl Chua hee hon Tan Kewin Tien ho siah Yong Loo Lin school of Medicine National University of SingaporeSingapore 117594Singapore Division of Gastroenterology and hepatology National University Health SystemSingapore 119074Singapore Department of Medicine Ng Teng Fong General HospitalSingapore Division of Prosthodontics National University Centre for Oral HealthSingapore 119074Singapore

BACKGROUND Dental injury is the leading cause of litigation in anaesthesia but an underrecognized preventable complication of *** To determine frequency and effects of dental injury in endoscopy,we present findings from an audit of outpatient endoscopy procedures conducted at a tertiary university hospital and a systematic review of *** Retrospective review of 11265 outpatient upper endoscopy procedures over the period of 1 June 2019 to 31 May 2021 identified dental related complications in 0.284%of *** of literature identified a similar rate of 0.33%.REsULTs Pre-existing dental pathology or the presence of prostheses makes damage more likely but sound teeth may be ***-endoscopic history and tooth examination are key for risk stratification and may be conducted succinctly with limited time *** retrieval should be prioritized in the event of dental injury to minimize aspiration and be followed by prompt dental consultation for specific *** Dental complications occur in approximately 1 in 300 of upper endoscopy *** are easily preventable by pre-endoscopy *** to mitigate dental injury are also suggested.

关键词： Teeth Dental trauma Endoscopy Digestive system

Benefits of post-operative oral protein supplementation in gastrointestinal surgery patients: A systematic review of clinical trials

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World Journal of Gastrointestinal surgery 2016年第7期8卷 521-532页

作者： Mike Crickmer Colum P Dunne Andrew O'Regan J calvin Coffey suzanne s Dunne Graduate Entry Medical school University of Limerick Centre for Interventions in Infection Inflammation and Immunity (4i) University of Limerick Department of surgery University Hospital Limerick

AIM: To evaluate published trials examining oral postoperative protein supplementation in patients having undergone gastrointestinal surgery and assessment of reported ***: Database searches(MEDLINE, BIOsIs, EMBAsE, Cochrane Trials, Cinahl, and CAB), searches of reference lists of relevant papers, and expert referral were used to identify prospective randomized controlled clinical trials. The following terms were used to locate articles: "oral'' or "enteral'' and "postoperative care'' or "post-surgical'' and "proteins' ' or "milk proteins' ' or "dietary proteins' ' or "dietary supplements' ' or "nutritional supplements' '. In databases that allowed added limitations, results were limited to clinical trials that studied humans, and publications between 1990 and 2014. Quality of collated studies was evaluated using a qualitative assessment tool and the collective results ***: searches identified 629 papers of which, following review, 7 were deemed eligible for qualitative evaluation. Protein supplementation does not appear to affect mortality but does reduce weight loss, and improve nutritional status. Reduction in grip strength deterioration was observed in a majority of studies, and approximately half of the studies described reduced complication rates. No changes in duration of hospital stay or plasma protein levels were reported. There is evidence to suggest that protein supplementation should be routinely provided post-operatively to this population. however, despite comprehensive searches, clinical trials that varied only the amount of protein provided via oral nutritional supplements(discrete from other nutritionalcomponents) were not found. At present, there is some evidence to support routinely prescribed oral nutritional supplements that contain protein for gastrointestinal surgery patients in the immediate post-operative ***: The optimal level of protein supplementation required to maximise recovery in gastrointestin

关键词： Protein supplementation Gastrointestinal surgery Clinical trial Oral supplementation systematic review

Training stem cells for treatment of malignant brain tumors

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World Journal of stem Cells 2014年第4期6卷 432-440页

作者： shengwen calvin Li Mustafa h Kabeer Long T Vu Vic Keschrumrus.h.ng Zhen Yin Brent A Dethlefs Jiang F Zhong John h Weiss William G Loudon Neuro-On-cology and stem Cell Research Laboratory Center for Neurosci-ence ResearchChildren’s Hospital of Orange CountyUniversity of California-IrvineOrangeCA 92868United States Department of Neurology University of California IrvineOrangeCA 92862United States Department of Pathology University of Southern CaliforniaLos AngelesCA 90033United States

The treatment of malignant brain tumors remains a challenge. stem cell technology has been applied in the treatment of brain tumors largely because of the ability of some stem cells to infiltrate into regions within the brain where tumor cells migrate as shown in preclinical studies. however, not all of these efforts can translate in the effective treatment that improves the quality of life for pa-tients. here, we perform a literature review to identify the problems in the field. Given the lack of efficacy of most stem cell-based agents used in the treatment of malignant brain tumors, we found that stem cell distribution(i.e., only a fraction of stem cells applied capable of targeting tumors) are among the limiting factors. We provide guidelines for potential improvements in stem cell distribution. specifically, we use an engineered tissue graft platform that replicates the in vivo microenvironment, and provide our data to validate that this culture platform is viable for producing stem cells that have better stem cell distribution than with the Petri dish culture system.

关键词： stem cells Malignant brain tumors Engineered tissue graft Organotypic slice model

千年简牍揭密,秦始皇“求仙问药”寻长生不老

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疯狂英语（新读写） 2018年第3期 44-44页

作者： calvin harris

中国第一位皇帝秦始皇生前一直寻求长生不老的秘方。根据中国考古学家的最新发现,秦始皇执政时广为下达＂求仙问药＂的全国政令。一批近年出土的千年简牍证实了秦始皇当年如何急欲寻求不死秘方。

关键词：秦始皇简牍考古学秘方中国出土