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Worldwide trends in esophageal cancer survival,by sub-site,morphology,and sex:an analysis of 696,974 adults diagnosed in 60 countries during 2000-2014(CONCORD-3)

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Cancer Communications 2023年第9期43卷 963-980页

作者： Melissa Matz Mikhail Valkov Mario Šekerija Sabine Luttman Adele caldarella Michel P Coleman Claudia Allemani the CONCORD Working Group Cancer Survival Group Department of Non-Communicable Disease EpidemiologyLondon School of Hygiene and Tropical MedicineLondon WC1E 7HTGreater LondonUnited Kingdom Department of Radiology Radiotherapy and OncologyNorthern State Medical UniversityArkhangelskArkhangelsk OblastRussia Croatian National Cancer Registry Croatian Institute of Public HealthZagrebZagreb CountyCroatia Bremen Cancer Registry BremenBremenGermany Tuscany Cancer Registry Istituto per lo studio e la prevenzione oncologicaFlorenceTuscanyItaly Cancer Division University College London Hospitals NHS Foundation TrustLondon NW1 2BUGreater LondonUnited Kingdom Members listed at the end of the article

Background Esophageal cancer survival is poor worldwide,though there is some *** in the distribution of anatomical sub-site and morphological sub-type may help explain international differences in survival for all esophageal cancers *** estimated survival by anatomic sub-site and morphological sub-type to understand further the impact of topography and morphology on international comparisons of esophageal cancer *** We estimated age-standardized one-year and five-year net survival among adults(15-99 years)diagnosed with esophageal cancer in each of 60 participating countries to monitor survival trends by calendar period of diagnosis(2000-2004,2005-2009,2010-2014),sub-site,morphology,and *** For adults diagnosed during 2010-2014,tumors in the lower third of the esophagus were the most common,followed by tumors of overlapping sub-site and sub-site not otherwise *** proportion of squamous cell carcinomas diagnosed during 2010-2014 was generally higher in Asian countries(50%-90%),while adenocarcinomas were more common in Europe,North America and Oceania(50%-60%).From 2000-2004 to 2010-2014,the proportion of squamous cell carcinoma generally decreased,and the proportion of adenocarcinoma *** time,there were few improvements in age-standardized five-year survival for each ***-standardized one-year survival was highest in Japan for both squamous cell carcinoma(67.7%)and adenocarcinoma(69.0%),ranging between 20%-60%in most other ***-standardized five-year survival from squamous cell carcinoma and adenocarcinoma was similar for most countries included,around 15%-20%for adults diagnosed during 2010-2014,though international variation was wider for squamous cell *** most countries,survival for both squamous cell carcinoma and adenocarcinoma increased by less than 5%between 2000-2004 and *** Esophageal cancer survival remains poor in many *** distributions

关键词： Cancer esophagus morphology survival topography trends

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Cost-effectiveness of Fluorine-18-Fluorodeoxyglucose positron emission tomography in tumours other than lung cancer: A systematic review

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World Journal of Radiology 2014年第3期6卷 48-55页

作者： Salvatore Annunziata Carmelo caldarella Giorgio Treglia Institute of Nuclear Medicine Catholic University of the Sacred Heart Department of Nuclear Medicine and PET/CT Center Oncology Institute of Southern Switzerland

AIM: To systematically review published data on the cost-effectiveness of Fluorine-18-Fluorodeoxyglucose positron emission tomography(FDG-PET) or PET/computed tomography(PET/CT) in tumours other than lung cancer. METHODS: A comprehensive literature search of studies published in PubMed/MEDLINE, Scopus and Embase databases through the 10th of October in 2013 was carried out. A search algorithm based on a combination of the terms:(1) "PET" or " PET/computed tomography(PET/CT)" or "positron emission tomography"; and(2) "cost-effectiveness" or "cost-utility" or "cost-efficacy" or "technology assessment" or "health technology assessment" was used. Only cost-effectiveness or cost-utility analyses in English language were included. Exclusion criteria were:(1) articles not within the field of interest of this review;(2) review articles, editorials or letters, conference proceedings; and(3) outcome evaluation studies, cost studies or health technology assessment reports. For each included study, information was col-lected concerning basic study, type of tumours evaluated, perspective/type of study, results, unit and comparison alternatives. RESULTS: Sixteen studies were included. Head and neck tumours were evaluated in 4 articles, lymphoma in 4, colon-rectum tumours in 3 and breast tumours in 2. Only one article was retrieved for melanoma, oesophagus and ovary tumours. Cost-effectiveness results of FDG-PET or PET/CT ranged from dominated to dominant. CONCLUSION: Literature evidence about the costeffectiveness of FDG-PET or PET/CT in tumours other than lung cancer is still limited. Nevertheless, FDGPET or PET/CT seems to be cost-effective in selective indications in oncology(staging and restaging of head and neck tumours, staging and treatment evaluation in lymphoma).

关键词： Positron emission tomography Positron emission tomography /computed tomography Fluorine-18-Fluorodeoxyglucose Cost-effectiveness Oncology

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Diagnostic accuracy of fluorine-18-fluorodeoxyglucose positron emission tomography in gallbladder cancer: A meta-analysis

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World Journal of Gastroenterology 2015年第40期21卷 11481-11488页

作者： Salvatore Annunziata Daniele Antonio Pizzuto Carmelo caldarella Federica Galiandro Ramin Sadeghi Giorgio Treglia Institute of Nuclear Medicine Department of Bioimaging and Radiological SciencesCatholic University of the Sacred Heart Postgraduate School of General Surgery Catholic University of the Sacred Heart Nuclear Medicine Research Center Mashhad University of Medical Sciences Department of Nuclear Medicine and PET Center Oncology Institute of Southern Switzerland

AIM: To meta-analyze published data about the diagnostic accuracy of fluorine-18-fluorodeoxyglucose(18F-FDG) positron emission tomography(PET) and PET/computed tomography(PET/CT) in the evaluation of primary tumor in patients with gallbladder cancer(GBCa).METHODS: A comprehensive literature search of studies published through 30 th June 2014 regarding the role of 18F-FDG PET and PET/CT in the evaluation of primary gallbladder cancer(GBCa) was performed. All retrieved studies were reviewed. Pooled sensitivity and specificity of 18F-FDG PET or PET/CT in the evaluation of primary GBCa were calculated. The area under the summary receiving operator characteristics curve(AUC) was calculated to measure the accuracy of these methods. Sub-analyses considering the device used(PET vs PET/CT) were carried ***: Twenty-one studies comprising 495 patients who underwent 18F-FDG PET or PET/CT for suspicious GBCa were selected for the systematic review. The meta-analysis of 13 selected studies provided the following results: sensitivity 87%(95%CI: 82%-92%),specificity 78%(95%CI: 68%-86%). The AUC was 0.88. Improvement of sensitivity and specificity was observed when PET/CT was ***: 18F-FDG-PET and PET/CT demonstrated to be useful diagnostic imaging methods in the assessment of primary tumor in GBCa patients,nevertheless possible sources of false-negative and false-positive results should be kept in mind. PET/CT seems to have a better diagnostic accuracy than PET alone in this setting.

关键词： Positron emission tomography Positron emission tom

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Oligodendroglioma: CD44 as a possible prognostic opportunity

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中国神经肿瘤杂志 2003年第3期1卷 143-143页

作者： Buccoliero AM caldarella a Arganini L Mennonna P Ammanati F Taddei A Taddei GL Dipartimento di Patologia Umana e Oncologia Universita degli Studi di FirenzeItaly

CD44, in its standard form as well in its isoforms, is a cell surface adhesion glycoprotein which occurs in a widevariety of non-neoplastic and neoplastic ceils. CD44 has been considered to be implicated in tumoral growth andin metastatic potential. We studied the immunohistochemical expression of CD44 standard in 30 oligodendrogliomas(19 primary lesions and 11 recurrences) in order to verify its possible prognostic role. Twelve primary oligoden-

关键词： CD44 as a possible prognostic opportunity Oligodendroglioma were

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