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用于塔里木地壳构造成像的重力场谱矩方法研究

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地球物理学报 2017年第8期60卷 3140-3150页

作者：杨文采孙艳云侯遵泽于常青浙江大学地球科学学院杭州310027 中国国土资源航空物探遥感中心北京100083 中国地质科学院地质研究所北京100037

现代地壳探测取得的各种地球物理场中包含有大量地壳构造信息,如果提取这些信息,可以在数学物理普适规律指导下计算出关于地壳构造的图件.由于区域重力场的高阶谱矩包含了场轮廓面的几何信息,可用于地质构造要素的分析计算,为地质构造... 详细信息

现代地壳探测取得的各种地球物理场中包含有大量地壳构造信息,如果提取这些信息,可以在数学物理普适规律指导下计算出关于地壳构造的图件.由于区域重力场的高阶谱矩包含了场轮廓面的几何信息,可用于地质构造要素的分析计算,为地质构造要素选取和定位的计算机自动制图提供理论依据.由地面布格重力场的二阶谱矩的统计不变量计算,可导出表征地壳变形带的脊形化系数,用于计算机自动制作区域地壳变形带分布图.脊形化系数强弱区的边界代表了活动的和稳定的构造单元的边界.在计算脊形化系数的基础上,还可进一步计算其二阶谱矩的统计不变量并作进一步增强处理,计算构造单元的边界系数,对地壳构造单元边界作连续和精细的追踪.文中介绍了脊形化系数和边界系数的计算方法,以及用在塔里木盆地进行地壳构造分析的结果.圈定了塔里木盆地深层满中高密度扰动带和满南、满北低密度扰动带,为深层油气勘探提供重要基础资料.

关键词：区域重力场地壳构造构造要素分析高阶谱矩地壳变形带构造单元边界追踪塔里木盆地

A transferrin receptor targeting dual-modal MR/NIR fluorescent imaging probe for glioblastoma diagnosis

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Regenerative Biomaterials 2024年第3期3卷 122-133页

作者： Jiaqi Hao Huawei cai Lei Gu Yiqi Ma yan Li Beibei Liu Hongyan Zhu Fanxin Zeng Min Wu Department of Radiology and Huaxi MR Research Center(HMRRC) Functional and Molecular Imaging Key Laboratory of Sichuan ProvinceWest China HospitalSichuan UniversityChengduSichuan 610041China Research Unit of Psychoradiology Chinese Academy of Medical SciencesChengduSichuan 610041China Department of Nuclear Medicine&Laboratory of Clinical Nuclear Medicine West China HospitalSichuan UniversityChengduSichuan 610041China State Key Laboratory of Biotherapy West China HospitalSichuan UniversityChengduSichuan 610041China Department of Clinical Research Center Dazhou Central HospitalDazhouSichuan 635000China

The prognosis of glioblastoma(GBM)remains challenging,primarily due to the lack of a precise,effective imaging technique for comprehensively *** GBM diagnostic challenges,our study introduces an innovative dual-modal imaging that merges near-infrared(NIR)fluorescent imaging with magnetic resonance imaging(MR).This method employs superparamagnetic iron oxide nanoparticies coated with NIR fluorescent dyes,specifically Cyanine 7,and targeted *** synthetic probe facilitates MRI functionality through superparamagnetic iron oxide nanoparticles,provides NIR imaging capability via Cyanine 7 and enhances tumor targeting trough peptide interactions,offering a comprehensive diagnostic tool for ***,the probe traverses the blood-brain barrier,targeting GBM in vivo via peptides,producing clear and discermible images in both *** and histopathology assessments confirm the probe's favorable safet *** findings suggest that the dual-modal MRINIR fluorescent imaging probe could revolutionize GBM prognosis and survival rate which can also be extended to other tumors type.

关键词： glioblastoma magnetic resonance imaging dual-modal probes near-infrared fluorescent targeting peptides

Joint Design of ISAC Waveform Under PAPR Constraints

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China Communications 2024年第7期21卷 186-211页

作者： Chen Yating Wen cai Huang yan Liang Le Li Jie Zhang Hui Hong Wei State Key Lab of Millimeter Waves Southeast UniversityNanjing 211100China School of Information Science and Technology Northwest UniversityXi’an 710127China National Mobile Communications Research Laboratory Nanjing 211100China College of Electronic and Information Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211100China

In this paper,we formulate the precoding problem of integrated sensing and communication(ISAC)waveform as a non-convex quadratically constrained quadratic programming(QCQP),in which the weighted sum of communication multi-user interference(MUI)and the gap between dual-use waveform and ideal radar waveform is minimized with peak-toaverage power ratio(PAPR)*** propose an efficient algorithm based on alternating direction method of multipliers(ADMM),which is able to decouple multiple variables and provide a closed-form solution for each *** addition,to improve the sensing performance in both spatial and temporal domains,we propose a new criteria to design the ideal radar waveform,in which the beam pattern is made similar to the ideal one and the integrated sidelobe level of the ambiguity function in each target direction is minimized in the region of *** limited memory Broyden-Fletcher-Goldfarb-Shanno(LBFGS)algorithm is applied to the design of the ideal radar waveform which works as a reference in the design of the dual-function *** results indicate that the designed dual-function waveform is capable of offering good communication quality of service(QoS)and sensing performance.

关键词： ambiguity function integrated sensing and communication MIMO OFDM PAPR waveform design

Accurate expression of neck motion signal by piezoelectric sensor data analysis

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Chinese Chemical Letters 2024年第9期35卷 250-256页

作者： Neng Shi Haonan Jia Jixiang Zhang Pengyu Lu Chenglong cai Yixin Zhang Liqiang Zhang Nongyue He Weiran Zhu yan cai Zhangqi Feng Ting Wang State Key Laboratory of Digital Medical Engineering National Demonstration Center for Experimental Biomedical Engineering EducationSchool of Biological Science and Medical EngineeringSoutheast UniversityNanjing 210096China SceneRay Co. Ltd.Suzhou 215123China School of Chemistry and Chemical Engineering Nanjing University of Science and TechnologyNanjing 210094China

The development of high-precision sensors using flexible piezoelectric materials has the advantages of high sensitivity,high stability,good durability,and *** main problem with sensing equipment is low sensitivity,which is due to the mismatch between materials and analysis methods,resulting in the inability to effectively eliminate *** address this issue,we developed the denoising analysis method to motion signals captured by a flexible piezoelectric sensor fabricated from poly(l-lactic acid)(PLLA)and polydimethylsiloxane(PDMS)*** results demonstrate that this improved denoising method effectively removes noise components from neck muscle motion signals,thus obtaining high-quality,low-noise motion signal *** decomposition and reconstruction is a signal processing technique that involves decomposing a signal into different scales and frequency components using wavelets and then selectively reconstructing the signal to emphasize specific features or eliminate *** study employed the sym8 wavelet basis for wavelet decomposition and *** the denoised signals,a high degree of stability and periodic peaks are distinctly manifested,while amplitude and frequency differences among different types of movements also become noticeably *** a result of this study,we are enabled to accurately analyze subtle variations in neck muscle motion signals,such as nodding,shaking the head,neck lateral flexion,and neck *** temporal and frequency domain analysis of denoised motion signals,differentiation among various motion states can be ***,this improved analytical approach holds broad application prospects across various types of piezoelectric sensors,such as healthcare monitoring,sports biomechanics.

关键词： Piezoelectric transducer Wavelet decomposition Muscle motion signal Signal analysis Noise component Healthcare monitoring

Bilayer Compounded Polytetrafluoroethylene Membrane for Enhanced Oil-Water Emulsion Separation

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Chinese Journal of Polymer Science 2024年第6期42卷 838-850页

作者： Yu-Liang yang Tai-Ran Zhang yan-Ting Han Shao-yun Guo Qin-Gong Rong Jia-Bin Shen State Key Laboratory of Polymer Materials Engineering Polymer Research Institute of Sichuan UniversitySichuan Provincial Engineering Laboratory of Plastic/Rubber Complex Processing TechnologyChengdu610065China West China Hospital/West China School of Nursing Sichuan UniversityChengdu610041China Shandong Senrong New Materials Co. Ltd.Zibo256401China

In order to achieve efficient and durable oil-water emulsion separation,the membranes possessing high separation efficiency and mechanical strength attract extensive attention and are in great *** present study,a kind of polytetrafluoroethylene(PTFE)-based bilayer membrane was fabricated by electrospinning fibrous PTFE(fPTFE)on an expanded PTFE(ePTFE)*** morphological observation revealed that the fibrous structure of the fPTFE layer could be tailored by controlling the formulation of spinning *** addition of appropriate polyoxyethylene(PEO)would make the fibers in the fPTFE layer finer and more *** a result,the compounded membrane exhibited a small pore size of approximately 1.25µm and a substantial porosity nearing 80%.This led to super-hydrophobicity,characterized by a high water contact angle(WCA)of 149.8°,and facilitated rapid oil *** water-in-oil emulsion separation experiment further confirmed that the compounded membrane not only had a high separation efficiency closing 100%,but such an outstanding separation capacity could be largely retained,either through multiple cycles of use or through strong acid(pH=1),strong alkali(pH=12),or high-temperature(100°C)***,the mechanical behavior of the bilayer membrane was basically contributed by that of each layer in terms of their volume *** significantly,the poor creep resistance of fPTFE layer was suppressed by compounding with ePTFE ***,this study has laid the groundwork for a novel approach to create PTFE-based compounded membranes with exceptional overall characteristics,showing promise for applications in the realm of emulsion separation.

关键词： ePTFE Electrospinning membrane Bilayer compounding Emulsion separation

Distinguished biological adaptation architecture aggravated population differentiation of Tibeto-Burman-speaking people

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Journal of Genetics and Genomics 2024年第5期51卷 517-530页

作者： yuntao Sun Mengge Wang Qiuxia Sun yan Liu Shuhan Duan Zhiyong Wang yunyu Zhou Jun Zhong Yuguo Huang Xinyu Huang Qingxin yang Xiangping Li Haoran Su yan cai Xiucheng Jiang Jing Chen Jiangwei yan Shengjie Nie Liping Hu Junbao yang Renkuan Tang Chuan-Chao Wang Chao Liu Xiaohui Deng Libing yun Guanglin He West China School of Basic Science&Forensic Medicine Sichuan UniversityChengduSichuan 610041China Institute of Rare Diseases West China Hospital of Sichuan UniversitySichuan UniversityChengduSichuan 610000China Center for Archaeological Science Sichuan UniversityChengduSichuan 610000China Faculty of Forensic Medicine Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong 510275China Guangzhou Forensic Science Institute GuangzhouGuangdong 510055China Department of Forensic Medicine College of Basic MedicineChongqing Medical UniversityChongqing 400331China School of Clinical Medical Sciences North Sichuan Medical CollegeNanchongSichuan 637100China School of Basic Medical Sciences North Sichuan Medical CollegeNanchongSichuan 637100China School of Forensic Medicine Kunming Medical UniversityKunmingYunnan 650500China School of Stomatology North Sichuan Medical CollegeNanchongSichuan 637100China Department of Medical Laboratory North Sichuan Medical CollegeNanchongSichuan 637007China School of Life Sciences Xiamen UniversityXiamenFujian 361005China Anti-Drug Technology Center of Guangdong Province GuangzhouGuangdong 510230China School of Forensic Medicine Shanxi Medical UniversityJinzhongShanxi030600China

Tibeto-Burman(TB)people have endeavored to adapt to the hypoxic,cold,and high-UV high-altitude environments in the Tibetan Plateau and complex disease exposures in lowland rainforests since the late Paleolithic ***,the full landscape of genetic history and biological adaptation of geographically diverse TB-speaking people,as well as their interaction mechanism,remain ***,we generate a whole-genome meta-database of 500 individuals from 39 TB-speaking populations and present a comprehensive landscape of genetic diversity,admixture history,and differentiated adaptative features of geographically different TB-speaking *** identify genetic differentiation related to geography and language among TB-speaking people,consistent with their differentiated admixture process with incoming or indigenous ancestral source populations.A robust genetic connection between the Tibetan-Yi corridor and the ancient Yellow River people supports their Northern China origin *** finally report substructure-related differentiated biological adaptative signatures between highland Tibetans and Loloish *** signatures associated with the physical pigmentation(EDAR and SLC24A5)and metabolism(ALDH9A1)are identified in Loloish people,which differed from the high-altitude adaptative genetic architecture in ***-related genomic resources provide new insights into the genetic basis of biological adaptation and better reference for the anthropologically informed sampling design in biomedical and genomic cohort research.

关键词： Tibeto-Burman people Genetic profile Natural selection Genetic diversity Biological adaptation

Impacts of Integrated Multi-Trophic Aquaculture on Phytoplankton in Sanggou Bay

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Journal of Ocean University of China 2024年第3期23卷 835-843页

作者： HAN Jichang LIU Xing PAN Kehou LIU Jiaojiao SUN yan JIN Guiyong LI yun LI Yuhang College of Food Science and Engineering Ningbo UniversityNingbo 315832China Key Laboratory of Mariculture(Ocean University of China) Ministry of EducationQingdao 266003China Function Laboratory for Marine Fisheries Science and Food Production Processes Qingdao National Laboratory for Marine Science and TechnologyQingdao 266100China Laboratory of Marine Organism Taxonomy and Phylogeny Institute of OceanologyChinese Academy of SciencesQingdao 266071China

Integrated multi-trophic aquaculture(IMTA)has been considered as an ecofriendly culture system providing a potential solution to environmental risks caused by intensive monoculture ***,the impact of IMTA on phytoplankton remains *** this study,the spatial and temporal variations of phytoplankton in Sanggou Bay were investigated seasonally based on 21 sampling sites covering three cultivation zones(bivalve zone,IMTA zone,and kelp zone)and one control zone(without aquatic cultivation).In total,128 phytoplankton species,with diatoms and dinoflagellates as the dominant groups,were obtained across the whole year,and the mean Shannon diversity index(H')and species richness(SR)were determined as 1.39 and 9.39,*** maximum chlorophyll a(Chl-a)(6.32μg L^(-1))and plankton diversity(H'of 1.97)occurred in summer and autumn,*** to other zones,the bivalve zone displayed significantly higher Chl-a and lower H'in majority of *** PERMANOVA analysis indicated that the phytoplankton assemblage in the bivalve zone was significantly different with the control and kelp zones,while the IMTA zone maintained close to other three *** on generalized additive models,temperature,NO_(2)^(-)-N,N/P ratio,SiO_(3)^(2-)-Si,and salinity were determined as the key factors underlying Chl-a and phytoplankton ***-tionally,the results of redundancy analysis further indicated that the phytoplankton assemblage in the bivalve zone is positively re-lated with nutrients such as NO_(3)^(-)-N and NH_(4)^(+)-N as well as water depth,while the phytoplankton assemblages in the kelp,control,and IMTA zones are associated with NO_(2)^(-)-N,SiO_(3)^(2-)-Si,and *** all observations into consideration together,it can be inferred that IMTA can effectively reduce Chl-a level compared to bivalve monoculture by reducing the ***,the SR,H’,and species composition of phytoplankton are primarily determined by local environment fa

关键词： phytoplankton diversity Sanggou Bay integrated multi-trophic aquaculture

Normal sperm head morphometric reference values in fertile Asian males

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Asian Journal of Andrology 2024年第3期26卷 315-320页

作者： Ye-Lin Jia Ying-Bi Wu Lin Yu yan Zheng Ting-Ting yang yan-yun Wang Bin Zhou Lin Zhang Fu-Ping Li Laboratory of Andrology West China Second University Hospital Human Sperm BankChengdu 610000China Laboratory of Molecular Translational Medicine Center for Translational MedicineChengdu 610061China Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University) Ministry of EducationChengdu 610061China NHC Key Laboratory of Chronobiology West China Second University HospitalSichuan UniversityChengdu 610000China

Sperm head morphology is crucial for male factor infertility diagnosis and assessment of male reproductive *** are available to analyze sperm head morphology,but they are limited by poor methodology comparability and *** study aimed to explore comprehensive and new normal morphometric reference values for spermatozoa heads infertile Asian *** automated sperm morphology analysis system captured 23152 stained spermatozoa from confirmed *** these samples,1856 sperm head images were annotated by three experienced laboratory technicians as“normal”.Weemployed 14 novel morphometric features to describe sperm head size(head length,head width,length/width ratio,and girth),shape(ellipse intersection over union,girth intersection over union,short-axis symmetry,and long-axis symmetry),area(head,acrosome,postacrosomal areas,and acrosome area ratio),and degrees of acrosome and nuclear *** straight-forwardmethod for the morphometric analysis of sperm by accurate visual measurements is clinically *** measured parameterspresent valuable information to establish morphometric reference intervals for normal sperm heads in fertile Asian *** detailed measurement data will be valuable for interlaboratory comparisons and technician *** vitro fertilizationand andrology laboratory technicians can use these parameters to perform objective morphology evaluation when assessing malefertilization potential.

关键词： fertile Asian males head morphometric reference value normal spermatozoa

Nomogram based on liver stiffness and spleen area with ultrasound for posthepatectomy liver failure:A multicenter study

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World Journal of Gastroenterology 2024年第27期30卷 3314-3325页

作者： Guang-Wen Cheng yan Fang Li-yun Xue Xiao-Hui Qiao Xue-Qi Li yan Zhang Jia Guo Xiao-yan Xie Hong Ding Department of Ultrasound Huashan HospitalFudan UniversityShanghai 200040China Department of Ultrasound Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Medical Ultrasonics Institute of Diagnostic and Interventional UltrasoundSun Yat-sen University First Affiliated HospitalGuangzhou 510080Guangdong ProvinceChina Institute of Ultrasound in Medicine and Engineering Shanghai Cancer CenterShanghai 200040China Department of Ultrasound Eastern Hepatobiliary Surgical HospitalSecond Military Medical UniversityShanghai 200433China Department of Ultrasound National Clinical Research Center for Aging and MedicineHuashan HospitalFudan UniversityShanghai 200040China

BACKGROUND Liver stiffness(LS)measurement with two-dimensional shear wave elastography(2D-SWE)correlates with the degree of liver fibrosis and thus indirectly reflects liver function *** size of the spleen increases due to tissue proliferation,fibrosis,and portal vein congestion,which can indirectly reflect the situation of liver fibrosis/*** was reported that the size of the spleen was related to posthepatectomy liver failure(PHLF).So far,there has been no study combining 2D-SWE measurements of LS with spleen size to predict *** prospective study aimed to investigate the utility of 2D-SWE assessing LS and spleen area(SPA)for the prediction of PHLF in hepatocellular carcinoma(HCC)patients and to develop a risk prediction *** To investigate the utility of 2D-SWE assessing LS and SPA for the prediction of PHLF in HCC patients and to develop a risk prediction *** This was a multicenter observational study prospectively analyzing patients who underwent hepatectomy from October 2020 to March *** 1 wk before partial hepatectomy,ultrasound examination was performed to measure LS and SPA,and blood was drawn to evaluate the patient’s liver function and other *** absolute shrinkage and selection operator logistic regression and multivariate logistic regression analysis was applied to identify independent predictors of PHLF and develop a *** performance was validated *** diagnostic performance of the nomogram was evaluated with receiver operating charac-teristic curve compared with the conventional models,including the model for end-stage liver disease(MELD)score and the albumin-bilirubin(ALBI)*** A total of 562 HCC patients undergoing hepatectomy(500 in the training cohort and 62 in the validation cohort)were enrolled in this *** independent predictors of PHLF were LS,SPA,range of resection,blood loss,international normalized ratio,and total *** diagnostic performanc

关键词： Shear-wave elastography Spleen Hepatectomy Posthepatectomy liver failure Hepatocellular carcinoma