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Bullous pemphigoid associated with acquired hemophilia A: A case report

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World Journal of Clinical Cases 2025年第4期13卷 28-33页

作者： Su-Ye Hu Meng-Can Li Zi-jia Hao Xu-Ya Chai Pei-Sai Li Yang Liu Li-xia Liu Ying Xu Pan-Pan Yang Ling-E Li Department of Dermatology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina Graduate School Hebei University of Traditional Chinese MedicineShijiazhuang 050051Hebei ProvinceChina Department of Pathology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina

BACKGROUND Acquired hemophilia A (AHA) is a rare and potentially severe bleeding disordercaused by circulating autoantibodies against factor Ⅷ (FⅧ). In approximately50% of the patients, the condition is associated with autoimmune diseases,cancers, medication use, pregnancy, and the post-partum period. Bullous pemphigoid(BP) is a chronic autoimmune subepidermal blistering disease associatedwith tissue-bound and circulating autoantibodies against BP antigens 180 (BP180)and 230 (BP230). AHA-associated BP has a high mortality rate;hence, the understandingof this disease must *** SUMMARY A 69-year-old man presented with erythema, blisters, blood blisters, and crustsaccompanied by severe pruritus for more than 20 days, and ecchymosis andswelling on his left upper arm for 3 days. Pathological examination revealed asubepidermal blister that contained eosinophils. Laboratory tests showed that theBP180 autoantibody levels had increased, isolated activated partial thromboplastintime was notably prolonged (115.6 s), and coagulation FⅧ activity wasextremely low (< 1.0%). Furthermore, the FⅧ inhibitor titer had greatlyincreased (59.2 Bethesda units). Therefore, the patient was diagnosed as having BP associated with AHA, prescribed 0.05% topical halometasone cream, and transferred to a higher-level hospitalfor effective treatment;however, he died after 2 *** AHA associated BP is rare, dangerous, and has a high mortality rate. Therefore, its timely diagnosis and effectivetreatment are necessary.

关键词： Bullous pemphigoid Acquired hemophilia A Acquired hemophilia A FactorⅧ Case report

Carbon shell coated hollow NiCoSe_(x)composite as high-performance anode for lithium storage

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Rare Metals 2021年第11期40卷 3185-3194页

作者： Zi-Zhong Chen jia-Gang Hou Ji Zhou Peng Huang Hai-Qing Wang cai-xia Xu Institute for Advanced Interdisciplinary Research(iAIR) University of JinanJinan 250022China Shandong Collaborative Innovation Center of Technology and Equipements for Biological Diagnosis and Therapy Jinan 250022China Qilu University of Technology(Shandong Academy of Sciences) Jinan 250353China

Hollow NiCoSe_(x)(H-NiCoSe_(x)) nanospheres encapsulated with carbon shell were prepared via one-step easy solvothermal method followed by the carbon coating process.H-NiCoSe_(x)@C has large interior void with the uniform dimension around 350 nm and the thickness of carbon shell around 20-30 *** with the large interior void as well as robust protective carbon shell,H-NiCoSe_(x)@C can retain the reversible capacity of 805.6 mAh·g^(-1) after 100 cycles at 200 mA·g^(-1).In particular,H-NiCoSe_(x)@C delivers large reversible capacity of 1532.2 mAh·g^(-1) upon cycling for 1000 loops at 1000 mA·g^(-1)with the capacity retention as high as 128.2% upon long period of *** at the high rate of 3000 mA·g^(-1),its specific capacity still retains up to 659.3 mAh·g^(-1).The superior lithium storage performances for H-NiCoSe_(x)@C profit from its robust hollow core-shell structure as well as enhanced electrical conductivity and ion transport.

关键词： Selenide Hollow sphere Carbon shell Lithium-ion batteries Anode

Giant magnetoresistance in antiferromagnetic Mn2Au-based tunnel junction

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Science China(Physics,Mechanics & Astronomy) 2020年第9期63卷 111-117页

作者： Xing-Tao jia xiao-Lin cai Yu jia School of Physics and Electronic Information Engineering Henan Polytechnic UniversityJiaozuo 454000China International Laboratory for Quantum Functional Materials of Henan School of PhysicsZhengzhou UniversityZhengzhou 450001China Key Laboratory for Special Functional Materials of Ministry of Education School of Materials Science and EngineeringHenan UniversityKaifeng 475004China

Recent studies on the electrical switching of tetragonal antiferromagnet(AFM)via Neél spin-orbit torque have paved the way for the economic use of antiferromagnetic *** most difficult obstacle that presently limits the application of antiferromagnetic materials in spintronics,especially in memory storage applications,could be the small and fragile magnetoresistance(MR)in the AFM-based *** this study,we investigated the spin transports in Mn2Au-based tunnel junctions based on the first-principle scattering *** MRs more than 1000%are predicted in some Fe/MgO/Ag/Mn2Au/Ta junctions that are about the same order as that in an MgO-based ferromagnetic tunnel junction with same barrier *** interplay of the spin filtering effect,the quantum well resonant states,and the interfacial resonant states could be responsible for the unusual giant and robust MRs observed in these Mn2Au-based junctions.

关键词： Mn2Au giant magnetoresistance tunnel junction

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昆明市不同性角色MSM人群指长比特征分析

中国公共卫生 2017年第3期33卷 365-368页

作者：李彩霞贾曼红马艳玲罗红兵李琪王玉淼李真晖宋丽军章任重陆林昆明医科大学公共卫生学院云南昆明650500 云南省疾病预防控制中心昆明医科大学附属延安医院皮肤科

目的探讨云南省昆明市不同性角色男男性行为者(MSM)人群指长比(D)的特点。方法收集2014年12月—2015年4月到昆明彩云天空健康咨询服务中心进行咨询和检测的M SM人群,共115名,根据性角色不同,分为"1号","0号"和"0.5"号,采用人类体质测量... 详细信息

目的探讨云南省昆明市不同性角色男男性行为者(MSM)人群指长比(D)的特点。方法收集2014年12月—2015年4月到昆明彩云天空健康咨询服务中心进行咨询和检测的M SM人群,共115名,根据性角色不同,分为"1号","0号"和"0.5"号,采用人类体质测量法,分别检测47名"1号",37名"0号"、31名"0.5号"及115名对照组双手第2~5指的长度,分析其D(2D∶3D、2D∶4D、2D∶5D、3D∶4D、3D∶5D、4D∶5D)。结果昆明市M SM人群D的分布特点为:2D∶3D"1号">"0.5号">对照组。结论 D或许可作为昆明市MSM人群生物学标记。

关键词：男男性行为者性角色指长比(D)

On the sediment age estimated by ^(210)Pb dating: probably misleading “prolonging” and multiple-factor-caused “loss”

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Acta Oceanologica Sinica 2018年第6期37卷 30-39页

作者： jia jianjun YANG Yang cai Tinglu GAO jianhua xia xiaoming LI Yan GAO Shu State Key Laboratory of Estuarine and Coastal Research East China Normal University Key Laboratory of Coast and Island Development of MOE Nanjing University State Research Centre for Island Exploitation and Management Second Institute of Oceanography State Oceanic Administration College of the Environment and Ecology Xiamen University

The radionuclide ^（210） Pb is suitable for century-scale dating and has been used to calculate the sedimentation rate in a variety of environments. However, two common ways to apply 210 Pb dating techniques may give misleading results. One is ＂prolonging of age＂, i.e., using the calculated sedimentation rate to date back to 200 or 300 *** practice must be treated with caution because the 210 Pb dating techniques do not guarantee direct dating for ages much older than 100 years. Another is ＂loss of age＂, i.e., the calculated time span between the topmost layer and the 210 Pb background layer in cores is less than 100 years when an apparent sedimentation rate is used in the calculation. Here, we propose that based on the principle of 210 Pb dating, the upper limit of age suitable for direct210 Pb dating is between 110 and 155 years. The ＂prolonging＂ application is acceptable only if the sedimentary environment in the past several hundred years was stable and the sedimentation rate was generally constant, and verification with independent evidence（such as historical records or biomarker methodology） is ***, after analyzing many published and collected data, we found four possible reasons for the ＂loss of age＂. First, the compaction effect of sediment should be corrected in laboratory analysis or else the calculated age will be underestimated. Second, the accuracy and uncertainty of 210 Pb activity measurement affect the judgment of the background. To be cautious, researchers are apt to choose a background activity with a younger age. Third,use of a slightly smaller value of supported 210 Pb activity in a calculation will lead to considerable underestimation of the time span. Finally, later-stage erosion and migration are common for sedimentation, which lead to loss of sedimentary records and are often reflected as a ＂loss of age＂ in cores. We believe that proper use of 210 Pb dating data may provide helpful information on our understanding of sedi

关键词： ^210Pb dating sedimentation rate sediment flux

Spatiotemporal variation of soil organic carbon in the cultivated soil layer of dry land in the South-Western Yunnan Plateau, China

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Journal of Mountain Science 2017年第12期14卷 2484-2497页

作者： ZHAO Ji-xia DAI Fu-qiang HE Shou-jia ZHANG Qing LIU Gang-cai Key Laboratory of Mountain Surface Processes and Ecological Regulation Institute of Mountain Hazards and Environment Chinese Academy of Science University of Chinese Academy of Sciences College of Tourism and Land Resources Chongqing Technology and Business University Agricultural Environmental and Resources Research Institute Yunnan Academy of Agricultural Sciences

The dynamics of soil organic carbon(SOC)in cropland is one of the central issues related to both soil fertility and environmental safety. However, little information is available at county level regarding the spatiotemporal variability of SOC in the southwestern mountainous region of China. Thus, this study aimed to explore spatiotemporal changes of SOC in the cultivated soil layer of dry land in Mojiang County,Yunnan Province, China. Data were obtained from the second national soil survey(SNSS) of 1985 and soil tests for fertilizer application carried out by the Mojiang Agricultural Bureau in 2006. The ANOVA test was applied to determine any significant differences between the datasets, while semivariogram analysis was performed on geostatistics via an ordinary Kriging method in order to map spatial patterns of soil organic carbon density(SOCD). The results revealed that SOCD in the cultivated soil layer significantly decreased from 3.93 kg m^(-2) in 1985 to 2.89 kg m^(-2) in 2006, with a total soil organic carbon stock(SOCS) decrease of 41.54×10~4 t over the same period. SOCS levels fell most markedly in yellow-brown soil at a rate of51.52%, while an increase of 8.70% was found in the analysed latosol. Geostatistical analysis also showed that the recorded changes in SOCD between 1985 and2006 were spatially structured. The decreasing trend might be attributed to the combined action of intense cultivation, major crop residue removal without any protective tillage measures, unreasonable fertilization and natural climatic diversity inducing a large decrease in SOC in the studied cultivated dry land region of Mojiang County. Therefore, management measures such as protective tillage should be undertaken in order to enhance soil C sequestration.

关键词： Soil organic carbon Spatiotemporal changes Dry land Cultivated soil layer Yunnan Plateau

REFLECTION/TRANSMISSION CHARACTERISTICS OF A DISCONTINUOUS GALERKIN METHOD FOR MAXWELL'S EQUATIONS IN DISPERSIVE INHOMOGENEOUS MEDIA

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Journal of Computational Mathematics 2008年第3期26卷 347-364页

作者： xia Ji Wei cai Pingwen Zhang Department of Mathematics and Statistics University of North Carolina at Charlotte USA Department of Scientific and Engineering Computing Peking University Beijing China

In this paper, we analyze the transmission and reflection properties of a high order discontinuous Galerkin method for dispersive Maxwell＇s equations, originally proposed by Lu et al. [J. Comput. Phys. 200 （2004）, pp. 549-580]. We study the reflection and transmission properties of the numerical method for up to second-order polynomial elements for one- and two-dimensional Maxwell＇s equations with rectangular meshes. High order accuracy has been shown for reflection and transmission coefficients near material interfaces.

关键词： Discontinuous Galerkin Method Reflection Transmission

Retrospective analysis of influencing factors on the efficacy of mechanical ventilation in severe and critical COVID-19 patients

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World Journal of Clinical Cases 2021年第31期9卷 9481-9490页

作者： jia Zeng xiao-xia Qi Wan-Wan cai Ya-Ping Pan Yi Xie Department of Aviation Disease Naval Medical Center of PLAShanghai 200052China No.1 Department of Infection Optical Valley Campus of Hubei Maternal and Child Health Care HospitalWuhan 430073Hubei ProvinceChina Department of Traditional Chinese Medicine Naval Medical Center of PLAShanghai 200052China Department of Naval Diving Medicine Naval Medical Center of PLAShanghai 200052China Traditional Chinese Medicine Naval Medical Center of PLAShanghai 200052China Department of Hepatobiliary Surgery Naval Medical Center of PLAShanghai 200052China

BACKGROUND The novel coronavirus disease 2019(COVID-19)has spread widely around the world with strong infectivity,rapid mutation and a high mortality *** ventilation has been included in the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia(Trial Version 8)as an important treatment for severe and critical COVID-19 patients,but its clinical efficacy in COVID-19 patients is ***,it is necessary to study the influencing factors on the efficacy of mechanical ventilation in severe and critical COVID-19 *** The aim of this study was to determine the influencing factors on the efficacy of mechanical ventilation in severe and critical COVID-19 *** A total of 27 severe and critical COVID-19 patients were enrolled in this study and treated with mechanical ventilation at the Optical Valley Campus of Hubei Maternal and Child Health Care Hospital(Wuhan,Hubei Province)from February 20,2020 to April 5,*** to the final treatment outcomes,the patients were divided into the“effective group”and“death group.”The clinical data of the two groups,such as the treatment process and final outcome,were retrospectively analyzed in order to determine the specific curative effects on the two groups and the reasons for the differences in such curative effects,as well as to explore the factors related to *** This study enrolled 27 severe and critical COVID-19 patients,including 17 males(63.0%)and 10 females(37.0%).Their ages were 74.41±11.73-years-old,and 19 patients(70.4%)were over *** COVID-19 patients over 70-yearsold who were treated with mechanical ventilation died in 14 cases(82.4%);thus,this was the peak age.A total of 17 patients died of basic disease,16 of whom had more than two basic *** basic diseases were hypertension,diabetes,and cardiovascular and cerebrovascular *** the same time,13 patients(76.5%)died from an abnormal increase in blood *** them,eight had dia

关键词： COVID-19 Mechanical ventilation Efficacy Factors Prognosis

Behavior of NiCrAlY coating on the TC6 titanium alloy

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Journal of University of Science and Technology Beijing 2008年第2期15卷 167-172页

作者： Changqing xia xiaomin Peng jia Li School of Materials Science and Engineering Central South University Changsha 410083 China

A NiCrAlY coating was deposited on the TC6 titanium substrate by arc ion plating （ALP）. The structure and morphologies of the NiCrAlY coating were characterized by X-ray diffraction （XRD） and scanning electron microscopy （SEM）, and the influence of vacuum heat treatment on the element diffusion behavior was studied. The results showed that the y＇-Ni3Al phase was precipitated on the NiCrAlY coating after heat treatment. The Ni3（AI,Ti）, TiNi, and Ti2Ni intermetallic layers appeared at the interface from the outside to the inside at 700℃, and the thickness of the intermetallic layers increased with the increase in temperature. At 700℃ Ti and Ni were the major diffusion elements, and the diffusion of Cr was observed when the heat treatment temperature increased up to 870℃. The violent inward diffusion of Ni at 950℃ resulted in the degradation of the NiCrAlY coating.

关键词： NiCrAlY coating TC6 titanium alloy vacuum heat treatment microstructure interdiffusion