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Influence of polarization extinction ratio on distributed polarization coupling detection

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Optoelectronics Letters 2008年第4期4卷 292-294页

作者： XU Tlan-hua TANG Feng JING Wen-cai ZHANG Hong-xia jia Da-gong YU Chang-song ZHOU Ge ZHANG Yi-mo College of Precision Instrument ＆ Optoelectronics Engineering Key Laboratory for Optoelectronics Information and Technical Science of National Ministry of Education Tianjin University Tianjin 300072 China

Distributed polarization coupling in polarization-maintaining fibers can be detected by using a white light Michelson *** technique usually requires that only one polarization mode is ***,in practical measurement,the injection polarization direction could not be exactly aligned to one of the principal axes of the PMF,so the influence of the polarization extinction ratio should be *** on the polarization coupling theory,the influence of the incident polarization extinction on the measurement result is evaluated and analyzed,and a method for distributed polariza-tion coupling detection is developed when both two orthogonal eigenmodes are excited.

关键词：分布式偏振耦合检测极化衰落率白光迈克逊干涉计偏振模式

A Systematic Review and Meta-Analysis of Randomized Controlled Trials on Treating Ulcerative Colitis by the Integration Method of Heat-Clearing, Damp-Excreting, Spleen-Strengthening, and Stasis-Removing of Traditional Chinese Medicine with Western Medicine

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World Journal of Traditional Chinese Medicine 2020年第1期6卷 74-82页

作者： Zi-Jun jia Zhen-Huan Yang cai-xia jia Kun-Min xiao Yi-Qun Niu Jie Chen Shao-Jie Duan Shu-Kun Yao Yan Li Department of Gastroenterology Clinical Medical College of China-Japan Friendship HospitalBeijing University of Chinese Medicine Department of Gastroenterology China-Japan Friendship Hospital Department of Pharmacology of Integrated Chinese and Western Medicine School of Preclinical MedicineBeijing University of Chinese Medicine Department of Cardiovascular Medicine Dongfang HospitalThe Second Clinical Medical College of Beijing University of Chinese MedicineBeijingChina

Objective:The objective of this study was to systematically evaluate the clinical efficacy of the integration method of heat-clearing, dampness-excreting,spleen-strengthening, and stasis-removing from traditional Chinese medicine (TCM) combined with Western medicine for the treatment of ulcerative colitis(UC).Materials and Methods:The databases China National Knowledge Infrastructure,China Biology Medicinedisc(CBMdisc),WANFANG, VIP, and PubMed were searched for randomized controlled trials investigating the integration of the TCM methods of clearing heat,draining dampness, invigorating the spleen, and removing stasis, combined with Western medicine to treat UC from January 2009 to March 2019. Two reviewers independently conducted literature searches, screenings, data extractions, and literature bias evaluations. A meta-analysis was conducted using RevMan 5.3 and Stata 13.0 software. Results:In total, 15 studies involving 1289 patients were included. The results of the meta-analysis showed that the total effective rate of treatment in the experimental groups was higher than that of the control groups (relative risk [RR]=1.27, 95%confidence interval [CI]:1.21, 1.35, Z=8.74, P <0.00001). In the subgroup analysis, the total effective rate of oral TCM combined with Western medicine was higher than that of the control groups (RR=1.24, 95%CI:1.15, 1.33, Z=5.88, P <0.00001). The total effective rate of oral TCM with enemas combined with Western medicine was higher than that of the control group (RR=1.30, 95%CI:1.12, 1.50, Z=3.52, P=0.0004).The comparison between Western medicine alone and oral TCM combined with enteroscopy and Western medicine showed that the effective rate of enteroscopy (RR=1.18, 95%CI:1.05, 1.33, Z=2.86, P=0.004) and the symptom scores before and after treatment all improved more in the combined treatment groups than in those of the Western medicine group alone, with statistically significant differences (RR=-4.23, 95%CI:-4.93,-3.53, Z=11.84, P <0.00001)

关键词： Clearing heat draining dampness invigorating spleen meta-analysis removing stasis ulcerative colitis

Study on the Mechanism of Qingre Huoxue Prescription in the Intervention and Treatment of Acute Myocardial Infarction Based on Network Pharmacology

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World Journal of Traditional Chinese Medicine 2019年第4期5卷 220-227页

作者： cai-xia jia Jin-Ping Wang Fei-Long Zhang xiao-Han Pang Wei-Lu Wang Paulin-Xue Xu Kuo Gao jian-Xin Chen Pharmacology Major of Integrated Traditional Chinese and Western Medicine School of Preclinical MedicineBeijing University of Chinese Medicine Harvard Medical School 25 Shattuck Street BostonMA 02115USA Scientific Research and Experiment Center Dongfang HospitalBeijing University of Chinese MedicineBeijingChina

Objective:The objective is to study the mechanism of Qingre Huoxue prescription in the intervention and treatment of acute myocardial infarction(AMI)based on the method of network *** and Methods:Five databases were used to screen the chemical compounds and targets of Ligusticum wallichii(chuanxiong),Radix Paeoniae Rubra(chishao),Lignum acronychiae(jiangxiang),Safflower(honghua),Salvia miltiorrhiza(danshen),Scutellaria baicalensis(huangqin),and Ilex pubescens(mao dong qing)in Qingre Huoxue ***,Cytoscape-V3.2.1 software was used to construct the drug-component-target *** protein association networks'database and the Database for Annotation,Visualization,and Integrated Discovery(DAVID)were used to visualize the protein interaction,pathway enrichment,and ***:A total of 44 active ingredients were screened out in Qingre Huoxue *** them,178 targets and 41 compounds related to Qingre Huoxue prescription's function in treating AMI were *** the analysis of the drug-component-action target network on Qingre Huoxue prescription,14 key compounds and nine key targets with three scores above average were *** addition,pathway enrichment and biological processes were conducted with the aid of the DAVID;and 8 related pathways and 10 biological processes were associated with AMI and related diseases;the PI3 K-AKT signaling pathway,MAPK signaling pathway,and HIF-1 signaling pathway are the main pathways of Qingre Huoxue prescription for the treatment of AMI and related ***:Qingre Huoxue prescription could treat AMI by multiple components,targets,and *** study provides ideas and theoretical basis for further clinical studies on Qingre Huoxue prescription in treating AMI.

关键词： Acute myocardial infarction mechanism network pharmacology Qingre Huoxue prescription

Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li Wen‑xia Su jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

Design and experiment of electronic speckle shearing phase-shifting pattern interferometer

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Optoelectronics Letters 2008年第1期4卷 59-61页

作者： XU Tian-hua, JING Chao, JING Wen-cai, ZHANG Hong-xia, jia Da-gong, and ZHANG Yi-mo College of Precision Instrument & Optoelectronics Engineering, National Education ministry Key Laboratory of Opto- electronics Information and Technical Science, Tianjin University, Tianjin 300072, China College of Precision Instrument & Optoelectronics Engineering National Education ministry Key Laboratory of Optoelectronics Information and Technical Science Tianjin University Tianjin China

An electronic speckle shearing phase-shifting pattern interferometer (ESSPPI) based on Michelson interferometer was based in this paper. A rotatable mirror driven by a step motor in one of its reflective arm is used to generate an adjustable shearing and the mirror driven by piezoelectric transducer (PZT) in the other reflective arm was used to realize phase- shifting. In the experiments, the deformation of an aluminum plate with the same extern-force on different positions and different forces on the same position is measured. Meanwhile, the phase distribution and phase-unwrap image of the aluminum plate with the extern-force on its center position is obtained by the four-step phase-shifting method.

关键词：电子相移模式干涉仪设计实验研究迈克逊干涉计

高性能纤维表面改性及其双马树脂基复合材料界面

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高分子学报 2018年第3期28卷 323-335页

作者：陈平于祺熊需海刘东刘哲贾彩霞精细化工国家重点实验室大连理工大学化工学院大连116024 先进聚合物基复合材料辽宁省重点实验室沈阳航空航天大学沈阳110136

采用电感耦合射频等离子体(ICP)和介质阻挡放电(DBD)低温等离子体对高性能连续纤维表面进行改性,分别采用X光电子能谱(XPS)、原子力显微镜(AFM)和动态接触角测定仪(DCA)等分析测试手段系统地研究了等离子体处理时间、放电功率、放电气... 详细信息

采用电感耦合射频等离子体(ICP)和介质阻挡放电(DBD)低温等离子体对高性能连续纤维表面进行改性,分别采用X光电子能谱(XPS)、原子力显微镜(AFM)和动态接触角测定仪(DCA)等分析测试手段系统地研究了等离子体处理时间、放电功率、放电气压等对连续碳纤维、聚苯并二噁唑(PBO)纤维改性处理前后,纤维表面状态、表面组成、表面形貌、浸润性能的变化规律以及经等离子体处理前后纤维增强双马树脂基复合材料界面结构与性能的影响关系及变化规律、复合材料界面粘结和破坏机理.研究结果表明,经过等离子体处理后,纤维表面接枝上了大量的含羧基、羟基等极性官能团,表面粗糙度增加,表面自由能增加,纤维浸润性能得到明显改善,导致纤维与双马树脂基体界面层间剪切强度(ILSS)明显提高,复合材料的破坏模式由未处理的界面脱粘破坏转变为等离子体处理后的树脂基体破坏.最后,对纤维表面时效性及其对纤维增强双马树脂基复合材料界面性能的影响关系也进行了论述.

关键词：连续纤维等离子体处理技术复合材料界面纤维表面改性界面结构与性能

矩形截面螺旋通道内气液两相流局部含气率分布实验研究

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化工学报 2018年第6期69卷 2474-2480页

作者：蔡博夏国栋贾玉婷周燕昭宗露香北京工业大学传热强化与过程节能教育部重点实验室北京100124

应用电导探针测量技术,对矩形截面螺旋通道内气液两相流局部含气率进行实验研究。在不同的气相折算速度下,应用电导探针测量了弹状流弹单元的长度,并与可视化方法进行对比,验证了电导探针的可靠性,并为信号处理选择合适的阈值。分别在... 详细信息

应用电导探针测量技术,对矩形截面螺旋通道内气液两相流局部含气率进行实验研究。在不同的气相折算速度下,应用电导探针测量了弹状流弹单元的长度,并与可视化方法进行对比,验证了电导探针的可靠性,并为信号处理选择合适的阈值。分别在泡状流、弹状流及环状流三种流型的条件下,分析了气相与液相折算速度对局部含气率分布的影响。实验结果发现,螺旋通道气液两相局部含气率呈非对称的抛物线形分布,这种非对称性受流型和液相折算速度的影响。

关键词：矩形截面螺旋通道气液两相流电导探针局部含气率气泡

Visualization of the protective role of estrogen against female liver fibrosis via an ER viscosity NIR fluorescent probe

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Science China Chemistry 2025年第1期68卷 360-368页

作者： Zheng Liu Changyu Zhang Zipeng Li Wanying Ma jia Liu xiang xia Ning Xu Wen Sun jianjun Du jiangli Fan xiaojun Peng State Key Laboratory of Fine Chemicals Dalian University of Technology Ningbo Institute of Dalian University of Technology

Endoplasmic reticulum(ER) viscosity has emerged as a new potential biomarker for hepatic fibrosis(HF). Herein, we report the first ER-targeting viscosity-responsive near-infrared(NIR) fluorescent probe HBT-PP for investigations of HF *** twisted intramolecular charge transfer(TICT) and the excited state intramolecular proton transfer(ESIPT) are combined to endow HBT-PP with the selective response towards viscosity(～62-fold) and a super large stokes shift(～320 nm). HBT-PP mainly targets organelle ER and is able to image the drug-or alcohol-induced viscosity elevation in living cells. Significantly,HBT-PP was successfully applied to visualize the gender difference in HF and the protective role of estrogen in restraining HF progression. Of note, after 10 min of stain with HBT-PP, HF lesions showed a stage-based response, indicating the potential of this probe in fast and early diagnosis of HF. These results clearly demonstrated the promising application of HBT-PP as a new tool for exploring ER viscosity-involved physiological and pathological processes.

关键词： NIR fluorescent probe ER viscosity hepatic fibrosis gender difference estrogen

Dissecting the cell microenvironment of ovarian endometrioma through single-cell RNA sequencing

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Science China Life Sciences 2025年第1期68卷 116-129页

作者： jiangpeng Wu Siyu xia Wenting Ye Yan Sun Jing cai Fubing Yu Haiping Wen Xiuwei Yi Taikang Li Mingwei Chen jiayun Chen Ge Song Chuanbin Yang Yali Song Jigang Wang Department of Reproductive Medicine Dongguan Maternal and Child Health Care Hospital Department of Urology and Shenzhen Clinical Research Centre for GeriatricsShenzhen People's HospitalSouthern University of Science and Technology State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Artemisinin Research Centerand Institute of Chinese Materia MedicaChina Academy of Chinese Medical Sciences Reproductive Medicine Center Foshan Women and Children Hospital State Key Laboratory of Antiviral Drugs School of PharmacyHenan University

Ovarian endometrioma（OE）, also known as “chocolate cysts,” is a cystic mass that develops in the ovaries due to endometriosis and is a common gynecological condition characterized by the growth of endometrial tissue outside the uterus, leading to symptoms such as dysmenorrhea, pelvic pain, and infertility. However, the precise molecular and cellular mechanisms driving this pathophysiology remain largely unknown, posing challenges for diagnosis and treatment. Here, we employed integrated single-cell transcriptomic profiling of over 52,000 individual cells from endometrial tissues of OE patients and healthy donors and identified twelve major cell populations. We identified notable alterations in cell type-specific proportions and molecular signatures associated with OE. Notably, the activation of IGFBP5+macrophages with pro-inflammatory properties, NK cell exhaustion, and aberrant proliferation of IQCG+and KLF2+epithelium are key features and may be the potential mechanisms underlying the pathogenesis of OE. Collectively, our data contribute to a better understanding of OE at the single cell level and may pave the way for the development of novel therapeutic strategies.

关键词： ovary high-throughput sequencing transcriptomics gene expression analysis ligand-receptor analysis