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Ultrasensitive and accurate diagnosis of urothelial cancer by plasmonic AuNRs-enhanced fluorescence of near-infrared Ag_(2)S quantum dots

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Rare Metals 2022年第11期41卷 3828-3838页

作者： Dong Zhang cai-ping ding Xiao-Yue Zheng Jia-Zhou Ye Zi-Hai Chen Jian-Hua Li Ze-Jun Yan Jun-Hui Jiang You-Ju Huang Department of Urology&Nephrology Ningbo First HospitalThe Affiliated Hospital of Zhejiang UniversityNingbo315000China College of Material Chemistry and Chemical EngineeringKey Laboratory of Organosilicon Chemistry and Material TechnologyMinistry of EducationHangzhou Normal UniversityHangzhou311121China Anhui Shenghaitang Traditional Chinese Medicine Decoction Pieces Co. LtdBozhou236800China Anhui Topway Testing Services Co. Ltd.Xuancheng Economic and Technological Development ZoneXuancheng242000China

Urothelial carcinoma(UC)is a common malignant tumor in the urinary system with high recurrence rate and low survival rate 5 years after *** present,imaging examination and other diagnostic methods have some shortcomings such as invasiveness and ***,it is urgent to develop a simple,rapid,noninvasive,highly sensitive and highly specific strategy to diagnose ***,a high-performance fluorescence sensor was constructed by the plasmonic gold nanorods(AuNRs)-enhanced near-infrared(NIR)fluorescence of silver sulfide quantum dots(Ag_(2)S QDs).The designed sensor can be used for the fast and accurate detection of small molecule single-transmembrane protein(FXYD3),which is overexpressed in 90%of ureteral cancers and 84%of high-grade bladder *** to its high specificity,the NIR fluorescence sensor achieves the detection of FXYD3 in the range of 0.25-150 ng·ml^(-1)with a detection limit of 0.2 ng·ml^(-1).Importantly,it also can be used for accurate diagnosis of FXYD3 in the urine of patients with relevant cancers,and the results are consistent with clinical cystoscopy and pathological *** proposed fluorescence sensor provides a simple,ultrasensitive,reliable method for UC screening,tumor-grade classification and postoperative monitoring and will have great potential for clinical applications.

关键词： Urothelial carcinoma FXYD3 Plasmonic enhanced fluorescence Ultrasensitive Accurate diagnosis

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企业物流系统综合评价指标体系设计

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物流技术 2006年第3期25卷 186-187页

作者：蔡定萍江西财经大学物流管理系江西南昌330013

根据全面性、特殊性、可比性、可操作性原则,构建了企业物流系统综合评价指标体系,并建议采用主成分分析法对企业物流系统进行综合评价。

关键词：企业物流系统指标体系主成分分析法

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Investigation of the interaction between the Berberine Hydrochloride and Bovine Hemoglobin

Investigation of the interaction between the Berberine Hydro...

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第十六届全国化学热力学和热分析学术会议

作者： cai-ping ding,Xiao-Ling Li,Yan-Jun Hu~* Hubei Key Laboratory of Pollutant Analysis & Reuse Technology,Department of Chemistry,Hubei Normal University,Huangshi 435002

＜正＞The interaction between the small biomolecules of berberine hydrochloride（BH） and bovine hemoglobin（BHb） were studied by fluorescence spectrum and UV-Vis absorbance spectroscopy under the human physiological *** was observed from Figure 1 that a progressive decrease in the fluorescence intensity was caused by quenching with the addition of *** insert in Figure 1 shows that within the investigated concentrations range,the results agree with the Stern-Volmer equation,which indicated that the fluorescence quenching of BHb by BH is a result of the formation of BH-BHb complex. The thermodynamic parameters△H,△G,△S at different temperatures were calculated（Table 1）,and van der Waals and hydrogen bonds play an important role to stabilize the complex.

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Perovskite LiBaH3 for photo-assisted dinitrogen fixation

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Science China Chemistry 2025年

作者： Kaixun Cui Yeqin Guan Yongli cai Runze Wang Qianru Wang Wenbo Gao Jianping Guo ping Chen Department of Chemical Physics University of Science and Technology of China Dalian Institute of Chemical Physics Chinese Academy of Sciences Center of Materials and Optoelectronics Engineering University of Chinese Academy of Sciences

Establishing supply chains for future ammonia energy systems requires the development of efficient materials and processes for ammonia production under mild conditions. Recent researches disclose unique functionalities of binary alkali and alkaline earth metal hydrides in mediating ammonia synthesis. Thanks to the rich compositional and structural properties of the metalhydrogen system, we herein report that LiBaH3, as a narrow band gap perovskite hydride, exhibits a strong response to visible light illumination. Specifically, hydridic hydrogen undergoes reductive elimination of producing H2and creates an electron-rich surface. Such an environment favors dinitrogen fixation to form N–H bonds. Based on this chemical property, a chemical looping ammonia synthesis process mediated by LiBaH3and driven by both photo and thermal energies was proposed and *** work demonstrates that hydride perovskites are promising candidates for mediating photo-assisted nitrogen fixation reactions.

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Achieving ultralow leakage current in Schottky-MIS cascode anode lateral field-effect diode based on AlGaN/GaN HEMT

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Science China(Information Sciences) 2025年第1期68卷 379-385页

作者： Fangzhou WANG Changhong GAO Guojian ding Cheng YU Zhuocheng WANG Xiaohui WANG Qi FENG ping YU Peng ZUO Wanjun CHEN Yang WANG Haiqiang JIA Hong CHEN Bo ZHANG Zeheng WANG Songshan Lake Materials Laboratory School of Microelectronics Southern University of Science and Technology State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of China Manufacturing Commonwealth Scientific and Industrial Research Organisation

In this paper,we design and fabricate a Schottky-metal-insulator-semiconductor（MIS） cascode anode GaN lateral field-effect diode（CA-LFED） to achieve ultralow reverse leakage current(ILEAK).The device based on AlGaN/GaN highelectron-mobility-transistor（HEMT） includes a normally-off MIS-controlled channel that is cascoded with a high barrier height Schottky *** reverse bias,the high electric-field is effectively prevented by the normally-off MIS-controlled channel *** with the high barrier height Schottky contact,this feature significantly suppresses the *** by the device fabrication,the CA-LFED with high breakdown voltage（BV）>600 V shows an ultralow ILEAKof 3.6×10-9A/mm as well as a low forward voltage drop（VF） of 2.2 *** performance suggests that the CA-LFED can be a promising candidate for ultralow ILEAKand better VF-ILEAKtrade-off GaN power diode applications.

关键词： Schottky-MIS cascode anode lateral field-effect diode (LFED) ultralow reverse leakage current ($I_{\rm{LEAK}}$) forward drop and reverse leakage trade-off AlGaN/GaN HEMTs

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1.5TMRI扫描PWI成像评估脑星形细胞瘤WHO分级诊断的效果

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海南医学 2022年第24期33卷 3225-3228页

作者：李辉蔡定萍姚俊安康市中心医院影像中心陕西安康725000

目的分析1.5T核磁共振成像(MRI)扫描灌注加权(PWI)成像评估脑星形细胞瘤WHO分级诊断的效果。方法选取2019年3月至2022年1月安康市中心医院收治且经手术病理确诊的125例脑星形细胞瘤为研究对象,根据组织病理分级,其中低级别组(WHOⅠ~Ⅱ... 详细信息

目的分析1.5T核磁共振成像(MRI)扫描灌注加权(PWI)成像评估脑星形细胞瘤WHO分级诊断的效果。方法选取2019年3月至2022年1月安康市中心医院收治且经手术病理确诊的125例脑星形细胞瘤为研究对象,根据组织病理分级,其中低级别组(WHOⅠ~Ⅱ级) 61例,高级别组(WHOⅢ~Ⅳ级) 64例。比较不同级别星形细胞瘤的血流灌注参数变化;采用Pearson相关评估相对脑血容量(rCBV)值、相对脑血流量(rCBF)值、相对平均通过时间(rMTT)与病理分级相关性;以手术病理结果为金标准,应用准确度、灵敏度、特异度、阳性预测值及阴性预测值分析灌注参数的诊断价值。结果高级别组患者的rCBV、rCBF分别为4.26±2.17、2.34±1.34,明显高于低级别组的1.42±0.38、1.23±0.26,差异均有统计学意义(P0.05);经Pearson相关分析结果显示,rCBV、rCBF与病理分级呈正相关(r=0.426、0.563,P0.05);以手术病理结果为金标准,MRI平扫+增强对高、低级别星形细胞瘤分级诊断准确度为65.23%、灵敏性为68.33%、特异性为63.27%,PWI成像中rCBV准确度为83.96%,阳性预测值为91.56%;rCBF准确度为81.73%,阳性预测值为90.43%;rMTT准确度为77.53%,阳性预测值为88.26%。结论 MRI扫描PWI成像对脑星形细胞瘤WHO分级诊断效果良好,对于后续治疗和预后指导具有重要价值。

关键词： 1.5T核磁共振成像灌注加权成像脑星形细胞瘤 WHO分级诊断价值

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Modular assembly of complex C-alkyl glycoside enabled via cooperative NHC and photoredox catalysis

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Science China Chemistry 2025年

作者： Rui-Qiang Jiao Ming Li Xi Chen Mei-Ze Xu Tian ding Xiao-ping Gong Zhuo-Mei Li Xue-Yuan Liu Yong-Min Liang State Key Laboratory of Applied Organic Chemistry Lanzhou University College of Chemistry and Chemical Engineering Northwest Normal University

C-Alkyl glycosides are found in natural products and are indispensable in drug development programs,owing to their diverse range of medicinal ***-component reactions involving glycosyl radical addition are well documented and proved efficient for the C-alkyl glycosides ***,multicomponent reactions for the rapid and controllable construction of structurally diversified C-alkyl glycosides in a single step remains a significant challenge due to the issues associated with balancing reactivity,compatibility,and ***,we report an NHC and photoredox co-catalyzed three-component method to access complex and valuable C-alkyl *** protocol exhibits broad substrate scope and excellent chemoand ***,nine types of sugars are compatible with this *** addition,the generality of this catalytic strategy was further highlighted by the potential for scalable production,the feasibility of further modifications of the products and its successful application in the late-stage functionalization of pharmaceutical skeletons.

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Improvement of Mechanical Properties of Wood-Plastic Composite Floors Based on the Optimum Structural Design

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Acta Mechanica Solida Sinica 2016年第4期29卷 444-454页

作者： Yang Zhang ping Xue Yun ding Mingyin Jia Jianchen cai Xiaoming Jin College of Mechanical and Electrical Engineering Beijing University of Chemical Technology College of Mechanical Engineering Quzhou University

A study is carried out on the structural design of wood-plastic composite floors. The geometric parameters of the cavities, the structure, and the means to optimize the performance of these light boards are investigated. Various structural parameters of the boards, such as size, shape, and the pattern of cavities are also studied. The optimal structure can be determined by calculation and analysis of the strength, stiffness, weight and cost of the material. A finite element model for the mechanical analysis of wood-plastic composite floors is established; and the results are used to verify the strength criteria under bending deformation, which is the most common loading condition of flooring board.

关键词： wood plastic composite cavities flooring board optimal structure the finite element model

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Whittle’s Index Based Sensor Scheduling for Multiprocess Systems Under DoS Attacks

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Journal of Systems Science & Complexity 2024年第1期37卷 329-350页

作者： cai Zai ding Kemi Shenzhen Key Laboratory of Control Theory and Intelligent Systems Southern University of Science and TechnologyShenzhen 518055China.

In this paper,the authors consider how to design defensive countermeasures against DoS attacks for remote state estimation of multiprocess *** each system,a sensor will measure its state and transmits the data packets through an unreliable channel which is vulnerable to be jammed by an *** limited communication bandwidth,only a subset of sensors are allowed for data transmission,and how to select the optimal one to maximize the accuracy of remote state estimation is the focus of the proposed *** authors first formulate this problem as a Markov decision process and investigate the existence of optimal ***,the authors demonstrate the piecewise monotonicity structure of optimal *** the difficulty of obtaining an optimal policy of large-scale problems,the authors develop a suboptimal heuristic policy based on the aforementioned policy structure and Whittle’s ***,a closed form of the indices is derived in order to reduce implementation complexity of proposed scheduling policy and numerical examples are provided to illustrate the proposed developed results.

关键词： DoS attacks Kalman filter remote state estimation Whittle’s index.

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Recent progress in the interaction between energetic particles and tearing modes

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National Science Review 2022年第11期9卷 240-261页

作者： Huishan cai ding Li Chinese Academy of Sciences Key Laboratory of Geospace Environment School of Nuclear Sciences and TechnologyUniversity of Science and Technology of China Institute of Physics Chinese Academy of Sciences Songshan Lake Materials Laboratory

The dynamics of energetic particles and tearing modes and the interactions between them are of great significance for magnetically confined fusion plasmas. In this review, we focus on these issues in the context of tokamak plasmas. The interaction between energetic particles and tearing modes is considered from two perspectives:(i) the influence of energetic particles on tearing modes and(ii) the transport of energetic particles by tearing modes. The influence of energetic particles on tearing modes is described on the basis of a general dispersion relation for tearing modes. The effects of energetic particles are considered separately in the outer region and the island region of a tearing mode. The physics mainly results from the modification of the perturbed parallel current by energetic particles without wave–particle resonance. In addition, the resonance between energetic particles and tearing modes is also reviewed. For the transport of energetic particles, transport of both circulating and trapped energetic particles by tearing mode is reviewed. Our descriptions of physical phenomena here are based on an analytical approach, while the experiments and simulations are used to illustrate and confirm our results. Finally, a number of open issues are discussed.

关键词： magnetically confined plasma energetic particle tearing mode transport confinement tokamak

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