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Wolfberry extracts inhibit Aβ1-42 aggregation and rescue memory loss of AD drosophila

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Food Science and Human Wellness 2020年第1期9卷 64-70页

作者： cai-hong li Jun-li Yang CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical Physics(LICP)Chinese Academy of Sciences(CAS)Lanzhou 730000PR China University of Chinese Academy of Sciences CASBeijing 100049PR China

This study is to investigate the potential of wolfberry water extracts for the treatment of Alzheimer’s disease(AD)and the relationship between their anti-AD property and the geographic locations in *** extracts of all wolfberry samples showed the potent to decrease self-induced Aβ1-42 aggregation and Cu2+-induced Aβ1-42 aggregation and the antioxidant capacity as well as the bioactivity for binding biometal.A transgenic drosophila model assay revealed that TE of S1 and S6(S1-TE and S6-TE)at 100μg/mL demonstrated the potent rescue effect on memory loss compared to the positive control memantine at 20μg/*** study also revealed the polysaccharide extracts could contribute to their anti-AD property,and the anti-AD activity conspicuously depends on growing *** samples S1 and S6 showed much more potent anti-AD *** this study demonstrated that the Chinese commonly consumed wolfberry in boiling water might have the beneficial function to prevent AD pathology.

关键词： Aβ1−42 Antioxidant bioactivity Anti-AD potential Bio-metal Drosophila Wolfberry

Self-Organized Public-Key Management for Mobile Ad Hoc Networks Based on a Bidirectional Trust Model

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Wuhan University Journal of Natural Sciences 2006年第1期11卷 188-192页

作者： FU cai hong Fan li Rui-xian hong liang CHEN Jing College of Computer Science and Technology Huazhong University of Science and Technology Wuhan 430074 Hubei China

In traditional networks , the authentication is performed by certificate authoritys（CA）,which can＇t be built in distributed mobile Ad Hoc Networks however. In this pa per, we propose a fully self-organized public key management based on bidirectional trust model without any centralized authority that allows users to generate their public-private key pairs, to issue certificates, and the trust relation spreads rationally according to the truly human relations. In contrast with the traditional self-organized public-key management, the average certificates paths get more short, the authentication passing rate gets more high and the most important is that the bidirectional trust based model satisfys the trust re quirement of hosts better.

关键词： Ad Hoc networks self-organize bidirectional trust public key management.

Influence of Backbone Structure on Properties of Directly Polymerized Phenoxy Resins from Epichlorohydrin and Various Aromatic Dihydric Phenols Monomers

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Chemical Research in Chinese Universities 2007年第5期23卷 607-612页

作者： cai hong-li BI Da-wu SHAO Ke Zhong Shuang-ling NA Hui Alan G. MacDiarmid Institute College of Chemistry Jilin University Changchun 130021 P. R. China

A series of phenoxy resins was directly prepared through the polymerization of each of the various aromatic dihydric phenols and *** and 1H NMR spectra were recorded to characterize the structures of the *** GPC curves were used to determine the molecular weight *** addition,the thermal properties of the resins were studied with differential scanning calorimetry（DSC）and thermal gravimetric analysis（TGA）.The thermal stabilities of the polymers increased with the content of the benzene ring,pendant group increasing or biphenyl groups *** adhesive properties of the polymers were evaluated in terms of the lap shear strength with Fe-Fe *** fracture mechanisms were determined by SEM observation and it was found that there was an important participation of cohesive fracture ***,it has been demonstrated that the extension of these micro-cohesive mechanisms is directly correlated with the adhesive *** to these results,the phenoxy resin containing biphenyl groups presented a higher adhesive strength and could improve the adhesive property of the epoxy/phenoxy system to a certain extent.

关键词： Phenoxy resin Thermal property Adhesive property

Ultrasonic interventional analgesia in pancreatic carcinoma with chemical destruction of celiac ganglion

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World Journal of Gastroenterology 2006年第20期12卷 3288-3291页

作者： Tao Wang Fu-Zhou Tian Zhong-hong cai Xu li Tao Cheng li Shi Qi Cheng Department of The General Hospital of Chengdu Military Command Area Chengdu 610085 Sichuan Province China

AIM： To detect the therapeutic effects of chemical destruction of celiac ganglion in patients with pancreatic carcinoma with intractable pain. METHODS： Ninety-seven cases with advanced pancreatic carcinoma received chemical destruction of celiac ganglion-5 mL pure alcohol injection around celiac artery under ultrasonic guidance. The changes of visual analogue scale （VAS）, serum substance P （Sub P）, β-endopeptide （β-EP） and T-lymphocyte subtypes level were compared between pre- and post-therapy. RESULTS： Successful rate of puncture was 98.7%, with one failure. No serious complications such as traumatic pancreatitis, pancreatic fistula, abdominal cavity hemorrhage or peritoneal infection occurred. VAS, serum Sub P and β-EP level significantly changed after treatment （8.0 ± 2.3 vs 4.6 ± 2.1, 254.1 ± 96.7 vs 182.4 ± 77.6, 3.2 ± 0.8 vs 8.8 ± 2.1, P 〈 0.01, P 〈 0.05, P 〈 0.01） with complete relief rate 54.2%, partial relief rate 21.9%, ineffective rate 12.5% and recurrent rate 10.7%. The T-lymphocyte subtypes level remarkably increased when compared with that of pre-therapy （46.7 ± 3.7 vs 62.5 ± 5.5, P 〈 0.01）. CONCLUSION： Our study suggests that chemical destruction of celiac ganglion under ultrasonic guidance is highly safe, and can evidently relieve cancer pain and improve the cellular immunity in patients with advanced pancreatic carcinoma.

关键词： Pancreatic carcinoma Analgesia Chemical destruction Ultrasonic intervention Celiac ganglion

Rational design of metal selenides nanomaterials for alkali metal ion(li^(+)/Na^(+)/K^(+))batteries:current status and perspectives

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Rare Metals 2024年第5期43卷 1906-1931页

作者： Rui Sun Feng Xu cai-hong Wang Sheng-Jun Lu Yu-Fei Zhang Hao-Sen Fan College of Materials Science and Metallurgy Engineering Guizhou UniversityGuiyang550025China School of Chemistry and Chemical Engineering Guangzhou UniversityGuangzhou510006China

Recently,metal selenides have obtained widespread attention as electrode materials for alkali(li^(+)/Na^(+)/K^(+))batteries due to their promising theoretical capacity and ***,metal selenides,similar to metal oxides and sulfides,also suffer from severe volume explosion during repeated charge/discharge processes,which results in the structure collapse and the following pulverization of electrode ***,it leads to poor cycle stability and influencing their further *** order to solve these issues,some special strategies,including elemental doping,coupling with carbon materials,synthesis of the bimetal selenides with heterostructure,etc.,have been gradually applied to design novel electrode materials with outstanding electrochemical ***,the recent research progress on metal selenides as anodes for alkali ion batteries is summarized,including the regulation of crystal structure,synthesis strategies,modification methods,and electrochemical mechanisms and ***,the challenges of metal selenides and the perspective for future electrode material design are *** is hoped to pave a way for the development of metal selenide electrode materials for the potential applications for alkali metal ion(li^(+)/Na^(+)/K^(+))batteries.

关键词： Rational design Metal selenides Nanostructure li^(+) batteries Na^(+) batteries K^(+) batteries

New insights into the pre-lithiation kinetics of single-crystalline Ni-rich cathodes for long-life li-ion batteries

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Green Energy & Environment 2024年第3期9卷 556-564页

作者： Qiang Han Lele cai Zhaofeng Yang Yanjie Hu Hao Jiang Chunzhong li Shanghai Engineering Research Center of Hierarchical Nanomaterials School of Chemical EngineeringEast China University of Science and TechnologyShanghai200237China Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and EngineeringEast China University of Science and TechnologyShanghai200237China

Developing single-crystalline Ni-rich cathodes is an effective strategy to improve the safety and cycle life of li-ion batteries(liBs).However,the easy-to-loss of li and O in high-temperature lithiation results in unsatisfactory ordered layered structure and ***,we demonstrate the synthesis of highly-ordered and fully-stoichiometric single-crystalline liNi_(0.83)Co_(0.12)Mn_(0.05)O_(2)(SC-NCM83)cathodes by the regulation of pre-lithiation *** well-balanced pre-lithiation kinetics have been proved to greatly improve the proportion of layered phase in the intermediate by inhibiting the formation of metastable spinel phase,which promoted the rapid transformation of the intermediate into highly-ordered layered SC-NCM83 in the subsequent lithiation *** coating a layer of li_(2)O–B_(2)O_(3),the resultant cathodes deliver superior cycling stability with 90.9%capacity retention at 1C after 300 cycles in pouch-type full *** enhancement mechanism has also been *** findings exhibit fundamental insights into the pre-lithiation kinetics process for guiding the synthesis of high-quality singlecrystalline Ni-rich cathodes.

关键词： Single-crystalline cathode Ni-rich oxides Pre-lithiation li-ion batteries Surface modification

Research on casing deformation prevention technology based on cementing slurry system optimization

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Petroleum Science 2024年第2期21卷 1231-1240页

作者： Yan Yan Meng cai Wen-Hai Ma Xiao-Chuan Zhang li-hong Han Yong-hong liu State Key Laboratory for Performance and Structure Safety of Petroleum Tubular Goods and Equipment Materials CNPC Tubular Goods Research InstituteXi©an710077ShaanxiChina College of Mechanical and Electrical Engineering China University of Petroleum(East China)Qingdao266580ShandongChina Shale Gas Evaluation and Exploitation Key Laboratory of Sichuan Province Chengdu610095SichuanChina CNPC Daqing Oilfield Company Daqing163453HeilongjiangChina

The casing deformation prevention technology based on the optimization of cement slurry is proposed to reduce the casing deformation of shale oil and gas wells during hydraulic fracturing. In this paper, the fracture mechanism of hollow particles in cement sheath was firstly analyzed by discrete element method, and the effect of hollow particles in cement on casing deformation was investigated by laboratory experiment method. Finally, field test was carried out to verify the improvement effect of the casing deformation based on cement slurry modification. The results show that the formation displacement can be absorbed effectively by hollow particles inside the cement transferring the excessive deformation away from casing. The particles in the uncemented state provide deformation space during formation slipping. The casing with diameter of 139.7 mm could be passed through by bridge plug with the diameter of 99 mm when the mass ratio of particle/cement reaches 1:4. According to the field test feedback, the method based on optimization of cement slurry can effectively reduce the risk of casing deformation, and the recommended range of hollow microbeads content in the cement slurry is between 15% and 25%.

关键词： Cement slurry Hollow ceramsite Casing deformation Formation slip Field test

Nitrogen addition increased resistance of resident plant community to Solidago canadensis invasion by altering allelopathic effect

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Journal of Plant Ecology 2024年第2期17卷 110-121页

作者： Jing-Fang cai Kai Sun lin li Si-Ha A Yi-Luan Shen hong-li li School of Ecology and Nature Conservation Beijing Forestry UniversityBeijing 100083China The Key Laboratory of EcologicalProtection in the Yellow River Basin of National Forestry and Grassland Administration Beijing Forestry UniversityBeijing 100083China

Allelopathy plays an important role in the interaction between invasive and resident *** nitrogen(N)deposition has become a global problem,but it is unclear whether N enrichment affects the interaction between invasive and resident plants by affecting their ***,we performed a greenhouse experiment in which the resident plant community was grown under two levels of invasion by ***(invasion *** invasion)and fully crossed with two levels of allelopathy(with or without adding activated carbon)and two levels of N addition(with or without).The resident plant communities were constructed with eight herbaceous species that often co-occur with *** results showed that both allelopathy of *** and the resident plants had obvious positive effects on their own *** addition had more obvious positive effects on the resident plants under invasion than those that were not ***,N addition also altered the allelopathy of resident ***,N addition improved the allelopathy of resident plants when they were invaded but decreased the allelopathy of resident plants when they grew *** nitrogen addition had no obvious effect on ***,it reduced the allelopathy of *** results suggest that N addition could improve the resistance of resident plants to invasion by improving the allelopathy of resident plants and reducing the allelopathy of *** fndings provide a scientifc basis to manage and control the *** invasion.

关键词： allelochemicals biological invasion nutrient input nitrogen addition resident plants Solidago canadensis

Microstructural Evolutions and Mechanical Properties of Energetic Al_(1) (TiZrNbTaMoCr)_(15) High-Entropy Alloys

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Acta Metallurgica Sinica(English Letters) 2024年第4期37卷 620-632页

作者： Xuan-hong cai Zhen-Hua Wang Ben Niu Jin-Feng li Qing Wang Show authors Key Laboratory of Materials Modification By Laser Ion and Electron Beams(Ministry of Education)Engineering Research Center of High Entropy Alloy Materials(Liaoning Province)School of Materials Science and EngineeringDalian University of TechnologyDalian116024China Institute of Materials China Academy of Engineering PhysicsMianyang621908China

The present study focuses on investigating the microstructural evolutions and mechanical properties of energetic Al_(1)(TiZrNbTaMoCr)_(15) refractory high-entropy alloys with the different heat treatments at low Al content state. It is found that even with a reduction in the Al content, the strength of these alloys remains unaffected at room temperature and high temperature, while the plasticity improves significantly. In particular, the coherent BCC/B_(2) microstructure with needle-like B_(2) nanoprecipitates dispersed into the BCC matrix is formed in 873 K-aged Al_(1)Ti_(6)Zr_(2)Nb_(3)Ta_(3)Mo_(0.5)Cr_(0.5) alloy. Therefore, this alloy exhibits the highest compression yield strength (σ_(YS) = 1333 and 717 MPa) at room temperature and 1073 K, respectively. After 973 K-aged, the coherent BCC/B_(2) microstructure underwent destabilization, and the B_(2) phase transforms into the brittle Zr5Al3 phase which then coarsens and dominates the microstructure of S3-AlTa_(3) alloy after 1073 K-aged. Moreover, these current alloys exhibit exceptionally high theoretical exothermic enthalpy (ΔH), surpassing 11606 J·g^(−1), which highlights their significant potential as innovative high-performance energetic structural materials.

关键词： Refractory high-entropy alloy Coherent microstructure Mechanical property Exothermic enthalpy