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Predictive factors for lymph node metastasis in poorly differentiated early gastric cancer and their impact on the surgical strategy

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World Journal of Gastroenterology 2008年第26期14卷 4222-4226页

作者： Hua Li ping lu yang lu cai-gang liu hui-mian xu shu-bao wang jun-qing chen Department of Surgical Oncology First Affiliated Hospital of China Medial UniversityShenyang 110001 Liaoning Province China

AIM:To identify the predictive clinicopathological factors for lymph node metastasis (LNM) in poorly differentiated early gastric cancer (EGC) and to further expand the possibility of using endoscopic mucosal resection (EMR) for the treatment of poorly differentiated EGC. METHODS: Data were collected from 85 poorly- differentiated EGC patients who were surgically treated. Association between the clinicopathological factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. RESULTS: Univariate analysis showed that tumor size (OR = 5.814, 95% CI = 1.050 - 32.172, P = 0.044), depth of invasion (OR = 10.763, 95% CI = 1.259 - 92.026, P = 0.030) and lymphatic vessel involvement (OR = 61.697, 95% CI = 2.144 - 175.485, P = 0.007) were the significant and independent risk factors for LNM. The LNM rate was 5.4%, 42.9% and 50%, respectively, in poorly differentiated EGC patients with one, two and three of the risk factors, respectively. No LNM was found in 25 patients without the three risk factors. Forty-four lymph nodes were found tohave metastasis, 29 (65.9%) and 15 (34.1%) of the lymph nodes involved were within N1 and beyond N1, respectively, in 12 patients with LNM. CONCluSION: Endoscopic mucosal resection alone may be sufficient to treat poorly differentiated intramucosal EGC (≤ 2.0 cm in diameter) with no histologically-confirmed lymphatic vessel involvement. When lymphatic vessels are involved, lymph node dissection beyond limited (D1) dissection or D1+ lymph node dissection should be performed depending on the tumor location.

关键词： Poorly differentiated early gastriccancer Lymph node metastasis Clinicopathological characteristics Endoscopic mucosal resection

Electrochemical Lithium Storage Performance of Molten Salt Derived V_(2)SnC MAX Phase

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Nano-Micro Letters 2021年第10期13卷 266-275页

作者： Youbing Li Guoliang Ma hui Shao Peng Xiao jun lu jin xu jinrong Hou Ke chen Xiao Zhang mian Li Per OÅPersson Lars Hultman Per Eklund Shiyu Du Zhifang Chai Zhengren Huang Na jin Jiwei Ma Ying liu Zifeng Lin qing Huang Engineering Laboratory of Advanced Energy Materials Ningbo Institute of Industrial TechnologyChinese Academy of SciencesNingbo 315201ZhejiangPeople’s Republic of China Qianwan Institute of CNiTECH Ningbo 315336People’s Republic of China College of Materials Science and Engineering Sichuan UniversityChengdu 610065People’s Republic of China CIRIMAT UMR CNRS 5085 UniversitéToulouse III-Paul Sabatier118 route de Narbonne31062 Toulouse Cedex 9France Department of Physics Chemistry and Biology(IFM)Linköping University58183 LinköpingSweden School of Machine Engineering Dongguan University of TechnologyDongguan 523808People’s Republic of China Institute of New Energy for Vehicles School of Materials Science and EngineeringTongji UniversityShanghai 201804People’s Republic of China

MAX phases are gaining attention as precursors of two-dimensional MXenes that are intensively pursued in applications for electrochemical energy ***,we report the preparation of V_(2)SnC MAX phase by the molten salt method.V_(2)SnC is investigated as a lithium storage anode,showing a high gravimetric capacity of 490 mAh g−1 and volumetric capacity of 570 mAh cm^(−3) as well as superior rate performance of 95 mAh g^(−1)(110 mAh cm^(−3))at 50 C,surpassing the ever-reported performance of MAX phase ***-ported by operando X-ray diffraction and density functional theory,a charge storage mechanism with dual redox reaction is proposed with a Sn-Li(de)alloying reaction that occurs at the edge sites of V_(2)SnC particles where Sn atoms are exposed to the electrolyte followed by a redox reaction that occurs at V_(2)C layers with *** study offers promise of using MAX phases with M-site and A-site elements that are redox active as high-rate lithium storage materials.

关键词： MAX phase Molten salt Lithium storage High-rate Energy storage

Chinese guidelines for the diagnosis and treatment of hand, foot and mouth disease (2018 edition)

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World Journal of Pediatrics 2018年第5期14卷 437-447页

作者： Xing-wang Li Xin Ni Su-Yun Qian Quan wang Rong-Meng Jiang Wen-Bo xu Yu-cai Zhang Guang-jun Yu Qiang chen Yun-Xiao Shang cheng-Song Zhao hui Yu Ting Zhang gang liu hui-Ling Deng Jie Gao Xian-Gui Ran Qiao-Zhi yang Bian-Li xu xue-Yong Huang Xing-Dong Wu Yi-Xiao bao Yi-ping chen Zhi-Hai chen qing-Quan liu Guo-ping lu Chun-feng liu Rong-Bing wang Guo-Liang Zhang Fang Gu Hong-Mei xu Ying Li Tao yang Infectious Disease Diagnosis and Treatment Center Beijing Ditan Hospital Capital Medical UniversityBeijingChina Otorhinolaryngology Head andN eck Surgery Beijing Children’s HospitalCapital Medical UniversityBeijingChina Prediatric Intensive Care Unit Beijing Children’s Hospital of Capit al Medical UniversityBeijingChina National Institute For Viral Disease Control and Prevention Chinese Center for Disease Control and Pre ventionBeijingChina Children’s Hospital ofShanghai Jiaotong University ShanghaiChina Pneumology department Jiangxi Provincial Children’s HospitalNanchangChina Department of P ediatric Pneumology Shengjing Hospital of China Medical UniversityShenyangChina Department of Inf ectious Diseases Beijing Children’s HospitalCapital Medical UniversityBeijingChina Department of Inf ectious Diseases Children’s Hospital of Fudan UniversityShanghaiChina Digestive Department Children’s Hospital of Shanghai Jiaotong UniversityShanghaiChina Department of Inf ectious Diseases The Children’s Hospital of Xi'anXi’anChina Infection Control Offi ce Children’s Hospital ofShanghai Jiaotong UniversityShanghaiChina Department ofR espiratory Medicine People’s Hospital ofFuy ang CityFuyangChina Department of P ediatrics People’s Hospital of Liaoc heng CityLiaochengChina

Background Hand, foot, and mouth disease (HFMD) is a common infectious disease in childhood caused by an enterovirus (EV), and which is principally seen in children under 5 years of age. To promote diagnostic awareness and effective treat-ments, to further standardize and strengthen the clinical management and to reduce the mortality of HFMD, the guidelines for diagnosis and treatment have been developed. Methods National Health Commission of China assembled an expert committee for a revision of the guidelines. The com-mittee included 33 members who are specialized in diagnosis and treatment of HFMD. Results Early recognition of severe cases is utmost important in diagnosis and treatment of patients with HFMD. The key to diagnosis and treatment of severe cases lies in the timely and accurate recognition of stages 2 and 3 of HFMD, in order to stop progression to stage 4. Clinicians should particularly pay attention to those EV-A71 cases in children aged less than 3 years, and those with disease duration less than 3 days. The following indicators should alert the clinician of possible deterioration and impending critical disease: (1) persistent hyperthermia;(2) involvement of nervous system;(3) worsening respiratory rate and rhythm;(4) circulatory dysfunction;(5) elevated peripheral WBC count;(6) elevated blood glucose and (7) elevated blood lactic acid. For treatment, most mild cases can be treated as outpatients. Patients should be isolated to avoid cross-infection. Intense treatment modalities should be given for those severe cases. Conclusion The guidelines can provide systematic guidance on the diagnosis and management of HFMD.

关键词： Diagnosis Guidelines HFMD Treatment

Frontiers in high entropy alloys and high entropy functional materials

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Rare Metals 2024年第10期43卷 4639-4776页

作者： Wen-Tao Zhang xue-Qian wang feng-Qi Zhang Xiao-Ya Cui Bing-Bing Fan Jia-Ming Guo Zhi-Min Guo Rui Huang Wen Huang xu-Bo Li Meng-Ru Li Yan Ma Zhi-Hua Shen Yong-gang Sun De-Zhuang wang Fei-yang wang Li-Qiang wang Nan wang Tian-Li wang Wei wang Xiao-yang wang Yi-Han wang Fu-Jie Yu Yu-Zhen Yin Ling-Kun Zhang Yi Zhang Jian-yang Zhang Qi Zhao Yu-ping Zhao Xin-Dong Zhu Yasir Sohail Ya-Nan chen Tao feng Qi-Long Gao Hai-Yan He Yong-Jiang Huang Zeng-bao Jiao Hua Ji Yao Jiang Qiang Li Xiao-Ming Li Wei-Bing Liao Huai-jun Lin hui liu Qi liu qing-feng liu Wei-Di liu Xiong-jun liu yang lu Yi-ping lu Wen Ma xue-Fei Miao Jie Pan qing wang Hong-hui Wu Yuan Wu Tao yang Wei-Ming yang Qian Yu jin-Yu Zhang Zhi-gang chen Liang Mao yang Ren bao-Long Shen xun-Li wang Zhe Jia He Zhu Zhen-Duo Wu Si Lan School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China Jiangsu Key Laboratory for Advanced Metallic Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China Department of Physics City University of Hong KongHongKong 999077China School of Materials Science and Engineering Tianjin UniversityTianjin 300072China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China Department of Mechanical Engineering Research Institute for Advanced ManufacturingThe Hong Kong Polytechnic UniversityHong Kong 100872China Center of Electron Microscopy and State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Key Laboratory of Solidification Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China Institute of Advanced Wear&Corrosion Resistance and Functional Materials Jinan UniversityGuangzhou 510632China School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou 221116China School of Physical Sciences Great Bay UniversityDongguan 523000China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China Beijing Advanced Innovation Center for Materials Genome Engineering Research Institute for Carbon NeutralityUniversity of Science and Technology BeijingBeijing 100083China Department of Mechanical Engineering The University of Hong KongHong Kong 999077China School of Computing Macquarie UniversitySydney 2113Australia Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China State Key Laborato

Owing to their exceptional properties,high-entropy alloys(HEAs)and high-entropy materials have emerged as promising research areas and shown diverse ***,the recent advances in the field are comprehensively reviewed,organized into five *** first section introduces the background of HEAs,covering their definition,significance,application prospects,basic properties,design principles,and *** subsequent section focuses on cutting-edge high-entropy structural materials,highlighting developments such as nanostructured alloys,grain boundary engineering,eutectic systems,cryogenic alloys,thin films,micro-nano-lattice structures,additive manufacturing,high entropy metallic glasses,nano-precipitate strengthened alloys,composition modulation,alloy fibers,and refractory *** the following section,the emphasis shifts to functional materials,exploring HEAs as catalysts,magneto-caloric materials,corrosion-resistant alloys,radiation-resistant alloys,hydrogen storage systems,and materials for ***,the review encompasses functional high-entropy materials outside the realm of alloys,including thermoelectric,quantum dots,nanooxide catalysts,energy storage materials,negative thermal expansion ceramics,and high-entropy wave absorption *** paper concludes with an outlook,discussing future directions and potential growth areas in the *** this comprehensive review,researchers,engineers,and scientists may gain valuable insights into the recent progress and opportunities for further exploration in the exciting domains of high-entropy alloys and functional materials.

关键词： High entropy alloys Cutting-edge structural materials Cutting-edgefunctional materials

Transarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma(CHANCE001)

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1198-1207页

作者： Hai-Dong Zhu Hai-Liang Li Ming-Sheng Huang Wei-Zhu yang Guo-Wen Yin Bin-Yan Zhong jun-hui Sun Zhi-cheng jin Jian-Jian chen Nai-Jian Ge Wen-Bin Ding Wen-hui Li jin-Hua Huang Wei Mu Shan-Zhi Gu Jia-ping Li hui Zhao shu-Wei Wen Yan-Ming Lei Yu-Sheng Song Chun-wang Yuan Wei-Dong wang Ming Huang Wei Zhao Jian-Bing Wu Song wang xu Zhu Jian-jun Han Wei-Xin Ren Zai-Ming lu Wen-Ge Xing Yong Fan Hai-Lan Lin Zi-shu Zhang Guo-hui xu Wen-Hao Hu Qiang Tu Hong-Ying Su Chuan-Sheng Zheng Yong chen xu-Ya Zhao Zhu-Ting Fang Qi wang jin-Wei Zhao Ai-Bing xu Jian xu qing-Hua Wu Huan-Zhang Niu Jian wang feng Dai Dui-ping feng qing-Dong Li Rong-shu Shi Jia-Rui Li Guang yang Hai-Bin Shi Jian-Song Ji Yu-E liu Zheng cai Po yang yang Zhao Xiao-Li Zhu Li-Gong lu Gao-jun Teng Center of Interventional Radiology&Vascular Surgery Department of RadiologyZhongda HospitalMedical SchoolSoutheast UniversityNanjing 210009China Department of Minimally invasive Intervention The Affiliated Cancer Hospital of Zhengzhou UniversityZhengzhou 450008China Department of Interventional Radiology the Third Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510630China Department of Interventional Radiology Union Hospital of Fujian Medical UniversityFuzhou 350001China Department of Interventional Radiology Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical UniversityNanjing 210009China Department of Interventional Radiology The First Affiliated Hospital of Soochow UniversitySoochow UniversitySuzhou 215006China Hepatobiliary and Pancreatic Interventional Treatment Center Division of Hepatobiliary and Pancreatic SurgeryThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Interventional Radiology Eastern Hospital of Hepatobiliary SurgeryNavy Medical University(Second Military Medical University)Shanghai 200438China Department of Interventional Radiology Nantong First People’s HospitalNantong 226001China Department of Interventional Radiology Yancheng Third People’s HospitalYancheng 224008China Department of Minimally Invasive Interventional Therapy Sun YatSen University Cancer CenterGuangzhou 510060China Department of Vascular Surgery Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China. Department of Interventional Radiology Hunan Cancer HospitalChangsha 410031China Department of Interventional Oncology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080China Department of Interventional Radiology The Hospital of Nantong UniversityNantong 226001China Department of Interventional Therapy Shanxi Tumor HospitalTaiyuan 030001China Department of Interventional Radiology Tibet Autonomous Region People’s

There is considerable potential for integrating transarterial chemoembolization(TACE),programmed death-(ligand)1(PD-[L]1)inhibitors,and molecular targeted treatments(MTT)in hepatocellular carcinoma(HCC).It is necessary to investigate the therapeutic efficacy and safety of TACE combined with PD-(L)1 inhibitors and MTT in real-world *** this nationwide,retrospective,cohort study,826 HCC patients receiving either TACE plus PD-(L)1 blockades and MTT(combination group,n=376)or TACE monotherapy(monotherapy group,n=450)were included from January 2018 to May *** primary endpoint was progression-free survival(PFS)according to modified *** secondary outcomes included overall survival(OS),objective response rate(ORR),and *** performed propensity score matching approaches to reduce bias between two *** matching,228 pairs were included with a predominantly advanced disease *** PFS in combination group was 9.5 months(95%confidence interval[CI],8.4-11.0)versus 8.0 months(95%CI,6.6-9.5)(adjusted hazard ratio[HR],0.70,P=0.002).OS and ORR were also significantly higher in combination group(median OS,19.2[16.1-27.3]vs.15.7 months[13.0-20.2];adjusted HR,0.63,P=0.001;ORR,60.1%vs.32.0%;Plus PD-(L)1 blockades and MTT could significantly improve PFS,OS,and ORR versus TACE monotherapy for Chinese patients with predominantly advanced HCC in real-world practice,with an acceptable safety profile.

关键词： hepatocellular targeted matching

Plerixafor-based mobilization and mononuclear cell counts in graft increased the risk of engraftment syndrome after autologous hematopoietic stem cell transplantation

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Blood Science 2024年第3期6卷 48-54页

作者： Le-qing Cao Qi Wen Bo-Ning liu Zhen-Yu Zhao Xiao-hui Zhang Lan-ping xu Huan chen Yu wang lu Yu feng-Rong wang Xiao-jun Huang Xiao-Dong Mo Peking University People’s Hospital Peking University Institute of HematologyNational Clinical Research Center for Hematologic DiseaseBeijing Key Laboratory of Hematopoietic Stem Cell TransplantationBeijingChina Hainan General Hospital Hainan Affiliated Hospital of Hainan Medical UniversityHaikouChina Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijingChina Research Unit of Key Technique for Diagnosis and Treatments of Hematologic Malignancies Chinese Academy of Medical SciencesBeijing 2019RU029China

Engraftment syndrome(ES)is one of the most common complications in the early phase after autologous hematopoietic stem cell transplantation(ASCT),and we aimed to evaluate the incidence and risk factors for ES patients receiving ASCT in the era of plerixafor-based mobilization.A total of 294 were enrolled,and 16.0%(n=47)experienced ES after *** main clinical manifestations were fever(100%),diarrhea(78.7%),skin rash(23.4%),and hypoxemia/pulmonary edema(12.8%).Plerixafor-based mobilization was associated with higher counts of CD3^(+)cells,CD4^(+)cells,and CD8^(+)cells in *** univariate analysis of the total cohort,age≥60 years,receiving ASCT at complete remission(CR),higher number of mononuclear cell(MNC),CD3^(+)cell counts,CD4^(+)cells as well as CD8^(+)cells transfused and plerixafor-based mobilization were associated with ES after *** analysis showed that age≥60 years(P=0.0014),receiving ASCT at CR(P=0.002),and higher number of MNC transfused(P=0.026)were associated with ES in total *** plasma cell disease subgroup,age≥60 years(P=0.013),plerixafor-based mobilization(P=0.036),and receiving ASCT at CR(P=0.002)were associated with *** with more risk factors had a higher risk of *** 1-year probabilities of relapse,non-relapse mortality,and survival were comparable between patients with and without ***,plerixafor-based mobilization may influence the composition of T lymphocytes in grafts and increase the risk of ES,particularly in patients with plasma cell disease.

关键词： Autologous stem cell transplantation Engraftment syndrome Plerixafor Risk factors

Efficacy and safety of Shenyankangfu Tablet,a Chinese patent medicine,for primary glomerulonephritis:A multicenter randomized controlled trial

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Journal of Integrative Medicine 2021年第2期19卷 111-119页

作者： Jie Wu shu-wei Duan Hong-tao yang Yue-yi Deng Wei Li Ya-ni He Zhao-hui Ni Yong-li Zhan Shan Lin Zhi-yong Guo jun Zhu jing-ai Fang xu-sheng liu Li-hua wang Rong wang Nian-song wang Xiao-hong cheng Li-qun He ping luo Shi-ren Sun Ji-feng Sun Ai-ping Yin Geng-ru Jiang Hong-yu chen Wen-hu liu Hong-li Lin Meng Liang lu Ma Ming chen Li-qun Song Jian chen qing Zhu Chang-ying Xing Yun Li Ji-ning Gao Rong-shan Li Ying Li Hao Zhang Ying lu Qiao-ling Zhou jun-zhou Fu Qiang He Guang-yan cai Xiang-mei chen Department of Nephrology Chinese People’s Liberation Army General HospitalChinese People’s Liberation Army Institute of NephrologyState Key Laboratory of Kidney Diseases(2011DAV00088)National Clinical Research Center for Kidney DiseasesBeijing 100853China Department of Nephrology First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300192China Department of Nephrology Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China Department of Nephrology Shandong University of Traditional Chinese Medicine Affiliated HospitalJinan 250011.Shandong ProvinceChina Department of Nephrology Daping HospitalArmy Medical UniversityChongqing 400042China Department of Nephrology Renji HospitalShanghai Jiao Tong UniversityShanghai 200127China Department of Nephrology Guang’anmen HospitalChina Academy of Traditional Chinese Medical SciencesBeijing 100053China Department of Nephrology Tianjin Medical University General HospitalTianjin 300052China Department of Nephrology Changhai Hospital of ShanghaiNaval Medical UniversityShanghai 200433China Department of Nephrology West China HospitalChengdu 610083Sichuan ProvinceChina Department of Nephrology First Affiliated Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Nephrology Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of Nephrology Shanxi Medical University Second Affiliated HospitalTaiyuan 030001Shanxi ProvinceChina Department of Nephrology Shandong Provincial HospitalJinan 250021Shandong ProvinceChina Department of Nephrology and Rheumatology Affiliated Sixth People’s HospitalShanghai Jiao Tong UniversityShanghai 200233China Department of Nephrology Shaanxi Traditional Chinese Medicine HospitalXi'an 710003Shaanxi ProvinceChina Department of Nephrology Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 200021China Department of Nephrology Jilin University Se

Background:Shenyankangfu Tablet(SYKFT)is a Chinese patent medicine that has been used widely to decrease proteinuria and the progression of chronic kidney ***:This trial compared the efficacy and safety of SYKFT,for the control of proteinuria in primary glomerulonephritis patients,against the standard drug,losartan ***,setting,participants and intervention:This was a multicenter,double-blind,randomized,controlled clinical *** glomerulonephritis patients,aged 18-70 years,with blood pressure≤140/90 mmHg,estimated glomerular filtration rate(eGFR)>45 mL/min per 1.73 ㎡,and 24-hour proteinuria level of 0.5-3.0 g,were recruited in 41 hospitals across 19 provinces in China and were randomly divided into five groups:SYKFT,losartan potassium 50 mg or 100 mg,SYKFT plus losartan potassium 50 mg or 100 *** outcome measu res:The primary outcome was change in the 24-hour proteinuria level,after 48 weeks of ***:A total of 735 participants were *** percent decline of urine protein quantification in the SYKFT group after 48 weeks was 8.78%±2.56%(P=0.006)more than that in the losartan 50 mg group,which was 0.51%±2.54%(P=1.000)less than that in the losartan 100 mg *** with the losartan potassium 50 mg group,the SYKFT plus losartan potassium 50 mg group had a 13.39%±2.49%(Plus losartan potassium 100 mg group had a 9.77%±2.52%(P=0.001)greater reduction in urine *** a superiority threshold of 15%,neither was statistically ***,serum creatinine and serum albumin from the baseline did not change statistically *** average change in TCM syndrome score between the patients who took SYKFT(-3.00[-6.00,-2.00])and who did not take SYKFT(-2.00[-5.00,0])was statistically significant(P=0.003).No obvious adverse reactions were observed in any ***:SYKFT decreased the proteinur

关键词： Herbal medicine,Chinese Shenyankangfu Tablet Primary glomerulonephritis Randomized controlled trial Double blind Double dummy

The In-Flight Realtime Trigger and Localization Software of GECAM

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Research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： Xiao-Yun Zhao Shao-Lin Xiong Xiang-yang Wen Xin-Qiao Li Ce cai shuo Xiao Qi luo Wen-Xi Peng Dong-Ya Guo Zheng-Hua An Ke Gong jin-Yuan Liao Yan-Qiu Zhang Yue Huang lu Li Xing Wen Fei Zhang jing Duan chen-Wei wang Dong-Li Shi Peng Zhang Qi-Bin Yi Chao-yang Li Yan-Bing xu Xiao-Hua Liang Ya-qing liu Da-Li Zhang Xi-Lei Sun Fan Zhang gang chen Huan-Yu wang Sheng yang Xiao-jing liu Min Gao Mao-shun Li jin-Zhou wang Xing Zhou Yi Zhao wang-chen xue Chao Zheng Jia-Cong liu Xing-Bo Han jin-Ling Qi Jia Huang Ke-Ke Zhang Can chen Xiong-Tao yang Dong-Jie Hou Yu-Sa wang Rui Qiao Xiang Ma Xiao-Bo Li ping wang Xin-Ying Song Li-Ming Song Shi-Jie Zheng Bing Li Hong-Mei Zhang Yue Zhu Wei chen Jian-Jian He Zhen Zhang jin Hou Hong-jun wang Yan-Chao Hao Xiang-Yu wang Zong-Yuan yang Zhi-Long Wen Zhi Chang Yuan-Yuan Du Rui Gao Xiao-Fei Lan Yan-Guo Li gang Li xu-Fang Li Fang-jun lu Hong lu Bin Meng feng Shi hui wang hui-Zhen wang Yu-Peng xu Jia-Wei yang xue-Juan yang shuang-Nan Zhang Chao-Yue Zhang cheng-Mo Zhang Zhi-cheng Tang cheng cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Physics and Space Science College China West Normal UniversityNanchong 637002China Department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation Academy for Microsatellites of CAS Shanghai 201203China Changchun University of Science and Technology Changchun 130022China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2020 December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

10B-doped MCP detector developed for neutron resonance imaging at Back-n white neutron source

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Nuclear Science and Techniques 2024年第8期35卷 58-68页

作者： Qiang Li Li‑Jiao wang jing‑Yu Tang Xiang‑Biao Qiu Zhen chen Mao‑Yuan Zhao Chang‑jun Ning Kai Pan Wei xu Tao Li Su‑Peng lu Han Yi Rui‑Rui Fan Chang‑qing feng Rong Zhang Xiao‑yang Sun Qi An Hao‑Fan Bai Jiang‑Bo Bai Jie bao ping Cao Qi‑ping chen Yong‑Hao chen Zeng‑Qi Cui An‑Chuan Fan Fan‑Zhen feng Min‑Hao Gu Chang‑cai Han Zi‑Jie Han Guo‑Zhu He Yong‑cheng He yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei Jiang Zhi‑Jie Jiang Zheng‑Yao jin Ling Kang Bo Li Gong Li Xiao Li yang Li Jie liu Rong liu shu‑Bin liu Yi‑Na liu Guang‑Yuan luan Jie Ren Zhi‑Zhou Ren Xi‑Chao Ruan Zhao‑hui Song Kang Sun Zhi‑Xin Tan Sheng‑Da Tang jin‑cheng wang Peng‑cheng wang Zhao‑hui wang Zhong‑Wei Wen Xiao‑Guang Wu xuan Wu Cong Xia Yong‑Ji Yu Guo‑hui Zhang Hang‑Chang Zhang Lin‑Hao Zhang Qi‑Wei Zhang Xian‑Peng Zhang Yu‑Liang Zhang Yue Zhang Zhi‑Yong Zhang Zhi‑Hao Zhou Ke‑jun Zhu Chong Zou Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China North Night Vision Science and Technology(Nanjing)Research Institute Co.Ltd Nanjing 211106China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China China Academy of Engineering Physics Institute of Nuclear Physics and ChemistryMianyang 621900China USTC archaeometry lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China China Shipbuilding Trading Co. LtdBeijing 100044China

Neutron resonance imaging(NRI)has recently emerged as an appealing technique for neutron *** complexity surpasses that of conventional transmission imaging,as it requires a high demand for both a neutron source and ***,the progression of NRI technology has been sluggish since its inception in the 1980s,particularly considering the limited studies analyzing the neutron energy range above *** white neutron source(Back-n)at the China Spallation Neutron Source(CSNS)provides favorable beam conditions for the development of the NRI technique over a wide neutron energy range from eV to ***-sensitive microchannel plates(MCP)have emerged as a cutting-edge tool in the field of neutron detection owing to their high temporal and spatial resolutions,high detection efficiency,and low *** this study,we report the development of a 10B-doped MCP detector,along with its associated electronics,data processing system,and NRI experiments at the *** heavy elements such as gold,silver,tungsten,and indium can be easily identified in the transmission images by their characteristic resonance peaks in the 1–100 eV energy range;the more difficult medium-weight elements such as iron,copper,and aluminum with resonance peaks in the 1–100 keV energy range can also be *** particular,results in the neutron energy range of dozens of keV(Aluminum)are reported here for the first time.

关键词： Neutron resonance imaging 10B doped MCP detector White neutron source Sample nuclide identification