检索结果-南通市图书馆

Impact of sleep on gastrointestinal cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical oncology 2024年第6期15卷 677-683页

作者： Joshua lo Pahnwat T Taweesedt Makoto Kawai department of Internal Medicine Santa Clara Valley Medical CenterSan JoseCA 95128United States department of Psychiatry and Behavioral Sciences Stanford UniversityStanfordCA 94305United States Sierra Pacific Mental Illness Research Educationand Clinical Center(MIRECC)VA Palo Alto Health Care SystemPalo AltoCA 94304United States department of Psychiatry and Behavioral Sciences School of MedicineStanford UniversityRedwood CityCA 94063United States

Sleep problems have become a significant public health concern,affecting a large portion of the global population and have been linked to increased morbidity and *** incidence of gastrointestinal(GI)cancers continues to rise,posing a substantial burden on healthcare systems *** editorial aims to delve into the impact of sleep on GI cancers,including esophageal,gastric,colorectal,hepatobiliary,and pancreatic *** literature investigating the potential connections between GI cancers and sleep was *** considered aspects such as sleep duration,sleep disorders,and circadian rhythmicity,in order to explore the underlying mechanisms that can contribute to the development of GI cancers and propose avenues for future research.

关键词： Sleep cancer Gastrointestinal cancer Esophagus Stomach Colon Liver

Silicon-based optical phased a.ra. with a reconfigurable aperture for“gaze”scanning of LidAR

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2024年第5期12卷 932-940页

作者： HEMING HU YAFANG HE BAISoNG CHEN ZIMING WANG YINGZHI LI QIJIE XIE QUANXIN NA ZIHAo ZHI XUEToNG LI HUAN QU PATRICK lo JUNFENG SoNG State Key Laboratory of Integrated optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China Peng Cheng Laboratory Shenzhen 518000China Advance Micro Foundry Pte.Ltd. Singapore 117685Singapore

Light detection and ranging(LidAR)serves as one of the key components in the fields of autonomous driving,surveying mapping,and environment ***,dense points clouds are pursued by LidAR systems to provide high-definition 3d ***,the LidAR is typically used to produce abundant yet redundant data for scanning the homogeneous background of scenes,resulting in power waste and excessive processing ***,it is highly desirable for a LidAR system to“gaze”at the target of interest by dense scanning and rough sparse scans on the uninteresting ***,we propose a LidAR structure based on an optical phased a.ra.(oPA)with reconfigurable apertures to achieve such a gaze scanning *** virtue of the cascaded optical switch integrated on the oPA chip,a 64-,128-,192-,or 256-channel antenna can be selected discretionarily to construct an aperture with variable *** corresponding divergence angles for the far-field beam are 0.32°,0.15°,0.10°,and 0.08°,*** reconfigurable-aperture oPA enables the LidAR system to perform rough scans via the large beam spots prior to fine scans of the target by using the tiny beam *** this way,the oPA-based LidAR can perform the“gaze”function and achieve full-range scanning *** scanning time and power consumption can be reduced by 1/4 while precise details of the target are ***,we embed the oPA into a frequency-modulated continuous-wave(FMCW)system to demonstrate the“gaze”function in beam *** results show that the number of precise scanning points can be reduced by 2/3 yet can obtain the reasonable outline of the *** reconfigurable-aperture oPa.ra.oPA)can be a promising candidate for the applications of rapid recognition,like car navigation and robot vision.

关键词： reconfigurable optical antenna

Pisco grape pomace:Iron/copper speciation and antioxidant properties,towards their comprehensive utilization

在线全文

学校读者我要写书评

暂无评论

Food Bioscience 2022年第3期47卷 1213-1221页

作者： Fátima Rodríguez-ramos raúl cañas-sarazúa Vilbett Briones-Labarca departamento de Ingeniería en Alimentos Universidad de La SerenaAv.Raúl Bitrán Nachary 1305Box 5991720010La SerenaChile

The pisco and wine industry produces hundreds of tons of grape pomace each year in Chile,generating environmental problems,and demanding urgent strategies for its *** aim of this work was to study the pisco grape pomace based on a physicochemical characterization,an iron/copper speciation analysis,and the optimization for polyphenols recovery,establishing the polyphenolic profile,antioxidant properties,and the Fe^(2+)/Cu^(2+) chelating activity,to promote their revalorization as an ingredient with potential application in the food *** chemical characterization showed mainly high values for crude protein(15.36%dw)and potassium(9240.66 mg/kg).The Fe/Cu speciation depicted that iron and copper soluble forms in pisco pomace flour represented 70.57%and 52.18%,respectively,regarding total *** optimized extract showed mainly pyrogallol,catechin and epicatechin,with concentrations of 1078.43±60.14μg/g,883.20±7.57μg/g and,751.76±23.04μg/g,respectively,with a relevant antioxidant capacity by oxygen radical Absorbance capacity(oraC)of 1402.15μmol TE/g dw GPE and,a better chelating ability to complex Fe^(2+) than Cu^(2+).The pisco pomace was for the first time chemically characterize,showing it as a potential source of minerals and antioxidant biocompounds,making it a good candidate for nutritional applications,as a rich source of organic matter or even could be potentially utilized to produce value-added commodities,toward a circular economy.

关键词： Pisco grape pomace Polyphenols Chemical speciation analysis Antioxidant capacity Metal chelating ability

基于深度卷积神经网络的人员疏散时间快速预测方法

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

系统工程理论与实践 2024年第4期44卷 1376-1388页

作者：赵思琪陈娟王巧夏钤强卢紫嫣马剑西南交通大学交通运输与物流学院成都610031 西南交通大学地球科学与环境工程学院成都610031 香港理工大学土木与环境工程系中国香港999077

预测人员疏散时间是大规模人群管控、建筑平面布局优化的关键.现有研究关注人员疏散理论模型的建立,忽视了疏散模型的时间和空间复杂度高难以实现快速预测的这一问题.复杂建筑空间环境以及人员的空间分布是决定疏散时间长短的决定性因素... 详细信息

预测人员疏散时间是大规模人群管控、建筑平面布局优化的关键.现有研究关注人员疏散理论模型的建立,忽视了疏散模型的时间和空间复杂度高难以实现快速预测的这一问题.复杂建筑空间环境以及人员的空间分布是决定疏散时间长短的决定性因素,本文提出以建筑空间环境和人位置分布图像为输入的疏散时间快速计算方法.设计不同空间布局、不同疏散人数、不同出口个数及宽度的疏散场景,使用人员疏散元胞自动机模型(ca)开展模拟计算构建样本数据库.构建疏散时间快速预测模型FastEvacNet,训练标定该深度卷积神经网络模型,测试模型预测疏散时间的可靠度与效率.结果表明,在整个测试集上的MAPE值为8.21%,模型整体预测精度良好,泛化能力强.模型对疏散时间的预测用时几乎不依赖于疏散场景的复杂度,计算效率相较于ca模型提升三个数量级;当以数据流的形式传入网络进行批量预测时,可提升四个数量级.

关键词：疏散时间卷积神经网络元胞自动机计算效率

Foaming supramolecular surfactants for gas mobility control in naturally fractured carbonate reservoirs at high temperature,salinity,and hardness

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2022年第6期19卷 3134-3148页

作者： Enrique Soto-castruita.ra.l Hern andez-Altamirano Eduardo Buenrostro-González Erick-Emanuel Luna-Rojero Sung Jae Ko-Kim Violeta-Yasmín Mena-Cervantes Mirna Pons-Jiménez Jorge-Francisco ramírez-Pérez david-Aaσn Nieto-Alvarez Ricardo Cerón-camacho Jos e-Ernesto Pa.ra.raúl oviedo-Roa Jos e-Manuel Martínez-Magadán Rodolfo Cisneros-dévora Luis-S.Zamudio-Rivera Instituto Mexicano del Petr oleo Eje Central Lazaro Cardenas Norte 152Col.San Bartolo AtepehuacanCiudad de Mexico07730Mexico CoNACy T-Instituto Mexicano del Petroleo Eje Central Lazaro Cardenas Norte 152Col.San Bartolo AtepehuacanCiudad de Mexico07730Mexico Centro Mexicano para la Produccion mas Limpia Instituto Politecnico NacionalAvenida Acueducto s/nCol.La Laguna TicomanCiudad de Mexico07340Mexico Centro de Tecnologías para Exploracion y Produccion Camino de Terracería 800Col.San Jose NovilleroBoca delRíoVeracruz94286Mexico

oil production and mainte nance are essential issues in naturally fractured reservoirs because they are the largest and most productive on ***,they present early water and gas channeling but could be remediated by using foaming agents to control these phenomena through blocking channeling *** Mexico these reservoirs have pressure up to 5,500 psi,high temperature up to 200℃,salinity up to400,000 ppm,and hardness up to 250,000 ppm;due to these thermodynamic conditions,there has been no available technology to form stable enough *** this work,a foaming supramolecular surfactant with the capability to chelate ca^(2+)ions is *** a result,surfactant monomers are bridged by captured ca^(2+)cations leading to the formation of high-molecular-weight oligomers,which significantly increment the viscosity of the solution improving the foam stability,and since at this manner the ca2+cations are no longer available to precipitate as components of solid salts,the foaming supramolecular surfactant also performs as *** observations are explained through quantum theoretical *** foam is stable,effectively blocking the gas channels,whereas in presence of oil the foam is broken leading the oil to pass into the *** characteristic rheological properties of the foam allow its injection into the formation at a.ra.ge of flow rates,foam qualities,and shear stress to achieve the flooding and the blocking of a variety of fractured carbonate formations,and the change of the wettability of the matrix,which is a desirable behavior in a huff and puff process,as reported in a previous publication about a successful pilot test of this foam.

关键词： calcium chelation Foaming composition Supramolecular surfactant Molecular design Gas mobility control Flow assurance Improved oil recovery Conformance control

Endothelial dLC1 is dispensable for liver and kidney function in mice

在线全文

学校读者我要写书评

暂无评论

Genes & diseases 2022年第3期9卷 814-819页

作者： Ying Tan Su Hao lo department of Biochemistry and Molecular Medicine University of California-DavisSacramentoCA 95817USA

dLC1 is a focal adhesion molecule that regulates cell polarity,proliferation,migration,and ***1 functions as a tumor suppressor and its expression is often down-regulated *** malignant neoplasms of epithelial *** studies have suggested that lack of dLC1 in endothelial cells may contribute to the development of angiosarcoma,and that dLC1 mutations have been identified in patients with nephrotic syndrome,a disease mainly due to leaky glomerular filtration *** demonstrate whether lack of endothelial dLC1 induces angiosarcoma and/or damages glomerular capillaries leading to nephrotic syndrome,we have extended our analyses on endothelial cell-specific dLC1 knockout mice with focuses on their liver and kidney *** were monitored up to 24 months of ***,no histological or clinical difference was found between dLC1 knockout and wild type mice,indicating that lack of endothelial dLC1 alone does not compromise kidney and liver function in mice.

关键词： Angiosarcoma dLC1 Focal adhesion Nephrotic syndrome Tumor suppressor

Luminescent cyclometalated iridium(Ⅲ) dipyridoquinoxaline indole complexes as biological probes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2010年第10期53卷 2091-2098页

作者： lo Kenneth Kam-Wing LEUNG Arthur Ho-Hon department of Biology and Chemistry City University of Hong Kong

Four luminescent cyclometalated iridium(Ⅲ) dipyridoquinoxaline complexes appended with an indole moiety [Ir(N^C)2(N^N)] (PF6) (HN^C = 2-phenylpyridine, Hppy; N^N = 2-(N-(2-(indole-3-acetamido)ethyl)aminocarbonyl)dipyrido[3,2-f:2′,3′-h]quinox- aline, dpqC2indole (1a), N^N = 2-(N-(6-(indole-3-acetamido)hexyl)aminocarbonyl)dipyrido[3,2-f:2′,3′-h]quinoxaline, dpqC6indole (1b); HN^C = 7,8-benzoquinoline, Hbzq, N^N = dpqC2indole (2a), N^N = dpqC6indole (2b)) have been synthesized and characterized. Upon irradiation, all the complexes displayed moderately intense and long-lived luminescence under ambient condi-tions and in 77 K glass. on the basis of the photophysical data, the emission of the complexes has been assigned to an excited state of triplet metal-to-ligand charge-transfer (3MLCT) ((dπ(Ir)→π*(N^N)) character. Cyclic voltammetric studies revealed indole-based and iridium-based oxidations at ca. +1.10 V and +1.24 V vs. SCE, respectively, and ligand-based reductions at ca. -1.07 to-2.29 V vs. SCE. The interactions of the complexes with an indole-binding protein, bovine serum albumin (Bsa), have been examined by emission titrations.

关键词： binding indole iridium luminescence probes

HCV-specific immune responses induced by CIGB-230 in combination with IFN-α plus ribavirin

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第1期20卷 148-162页

作者： Yalena Amador-caizares Gillian Martínez-donato Liz lvarez-Lajonchere Claudia Vasallo Mariacarla dausá daylen Aguilar-Noriega carmen Valenzuela Ivette raíces Jean dubuisson Czeslaw Wychowski Zurina Cinza-Estévez Marlén castellanos Magdalys Núez Anny Armas Yaimé González Ismariley Revé Ivis Guerra ngel Pérez Aguiar santiago dueas-carrera Centro de Ingeniería Genética y Biotecnología Playa 10600HavanaCuba Center for Infection and Immunity of Lille (CIIL) Inserm U1019CNRS UMR8204Institut Pasteur de LilleUniv Lille Nord de FranceF-59000 LilleFrance Instituto de Gastroenterología Vedado 10400HavanaCuba Hospital Clínico Quirúrgico "Hermanos Amejeiras" Havana 10200Cuba Centro de Inmunoensayos Havana 11300Cuba

AIM: To analyze hepatitis C virus (HCV)-specific immune responses in chronically infected patients under triple therapy with interferon-α (IFN-α) plus ribavirin and CIGB-230.

关键词： Clinical trial dNA vaccine Enzyme-linked immunospot Hepatitis C virus Leukopenia

decomposition of perfluorooctanoic acid by microwaveactivated persulfate： Effects of temperature, pH, and chloride ions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2012年第1期6卷 17-25页

作者： Yuchi LEE Shanglien lo Jeff KUo Chinghong HSIEH1 Research Center for Environmental Pollution Prevention and Control Technology Graduate Institute of Environmental Engineering Taiwan University Taipei 10672 China department of Civil and Environmental Engineering California State University Fullerton CA 92834-6870 USA

Microwave-hydrothermal treatment of persis- tent and bioaccumulative perfluorooctanoic acid （PFoA） in water with persulfate （S2o2-） has been found effective. However, applications of this process to effectively remediate PFoA pollution require a better understanding on free-radical scavenging reactions that also take place. The objectives of this study were to investigate the effects ofpH （pH= 2.5, 6.6, 8.8, and 10.5）, chloride concentra- tions （0.01-0.15 mol.L-1）, and temperature （60℃, 90℃, and 130℃） on persulfate oxidation of PFoA under microwave irradiation. Maximum PFoA degradation occurred at pH 2.5, while little or no degradation at pH 10.5. lowering system pH resulted in an increase in PFoA degradation rate. Both high pH and chloride concentrations would result in more scavenging of sulfate free radicals and slow down PFoA degradation. When chloride concentrations were less than 0.04 mol.L^-1 at 90℃ and 0.06mol.L^-1 at 60℃, presence of chloride ions had insignificant impacts on PFoA degradation. However, beyond these concentration levels, PFoA degradation rates reduced significantly with an increase in chloride concentrations, especially under the higher temperature.

关键词： microwave perfluorooctanoic acid pH persulfate chloride ions perfluorocarboxylic acids