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Abstracts from the 15th International Myopia Conference

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Eye and Vision 2016年第1期3卷 211-221页

作者： Alexandra Benavente-Perez Ann Nour Tobin Ansel Kathleen Abarr luying Yan Keisha Roden David Troilo Chanyi lu Miaozhen Pan Min Zheng Jia Qu Xiangtian Zhou Christine F. Wildsoet Fan lu Jie Chen Jinhua Bao liang Hu Qinmei Wang Zibing Jin Frances Rucker Stephanie Britton Stephan Hanowsky Molly Spatcher Hui-Ying Kuo Ching-Hsiu Ke I-Hsin Kuo Chien-Chun Peng Han-Yin Sun Ian G. Morgan Jeremy A. Guggenheim Rupal l. Shah cathy Williams Jinglei Yang Peter S. Reinach Sen Zhang Wenfeng Sun Bo liu Fen li Xiaoqing li Aihua Zhao Tianlu Chen Wei Jia Jun Jiang Haoran Wu Kazuo Tsubota Hiroko Ozawa Hidemasa Torii Shigemasa Takamizawa Toshihide Kurihara Kazuno Negishi Klaus Graef Daniel Rathbun Frank Schaeffel ladan Ghodsi William K. Stell Machelle T. Pardue Ranjay Chakraborty Han na Park Curran S. Sidhu P. Michael Iuvone Michael J Collins Nethrajeith Srinvasalu Sally A. McFadden Paul N. Baird Pablo Artal Pauline Cho SW Cheung Pei-Chang Wu Quan V. Hoang Duk C. lee Erica G. landis Michael A. Bergen Curran Sidhu Samer Hattar Richard A. Stone Ravi Metlapally Ruiqin li Qinglin Xu Hong Zhong Chenglin Pan Weizhong lan Xiaoning li ling Chen Zhikuan Yang Scott A. Read Seang-Mei Saw Shi-Jun Weng Xiao-Hua Wu Kang-Wei Qian Yun-Yun li Guo-Zhong Xu Furong Huang Xiong-li Yang Yong-Mei Zhong Earl l Smith, III Baskar Arumugam li-Fang Hung lisa A. Ostrin Klaus Trier Monica Jong Brien A. Holden Thomas Chuen lam Samantha Shan Bing Zuo Dennis Yan-yin Tse Jingfang Bian King-Kit li Quan liu Chi-ho To Timothy J. Gawne John T. Siegwart, Jr. Alexander H. Ward Thomas T. Norton Yan Zhang Yue liu carol Ho Eileen Phan Abraham Hang Emily Eng Christine Wildsoet Department of Biological Sciences SUNY College of Optometry New York NY 10036 USA School of Optometry and Ophthalmology and Eye Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China Center for Eye Disease & Development School of Optometry & Vision Science Program University of California Berkeley Berkeley CA 94720-2020 USA Wenzhou Medical University Wenzhou Zhejiang 325027 China Biomedical Science and Disease New England College of Optom Boston MA USA School of Optometry Chung Shan Medical University Taichung City 402 Taiwan Institute of Medicine Chung Shan Medical University Taichung City 402 Taiwan Division of Biochemistry and Molecular Biology Research School of Biology Australian National University Canberra Australia State Key laboratory of Ophthalmology and Division of Preventive Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou China School of Optometry & Vision Sciences Cardiff University Cardiff UK School of Social and Community Medicine University of Bristol Bristol UK School of and Eye Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China State Key laboratory Cultivation Base and Key laboratory of Vision Science Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry Wenzhou Zhejiang 325027 People’s Republic of China Shanghai Key laboratory of Diabetes Mellitus and Center for Translational Medicine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai 200233 China Eye Hospital of Wenzhou Medical University Wenzhou Zhejiang 325027 China Department of Ophthalmology Keio University School of Medicine Shinjuku-ku Tokyo 160-8582 Japan General Medicine Ichikawa Medical Center Urayasu City Chiba 279-0001 Japan Ophthalmic Research Institute University of Tuebingen 72076 Tuebingen Germany Bernstein Center for Computational Neuroscience Tuebingen 72076 Tuebingen Germany Werner Reichardt Centre for Integrative Neuroscience Otfried-Mueller-Straße 25 Tueb

To assess the peripheral refractive changes that occur when eye growth decelerates in *** We measured peripheral refraction and on-axis vitreous chamber depth on a total of 53 marmosets;36 treated monocularly for 12 weeks 9 hrs/day(26 with-5 D contact lenses,10 with+5 D)and 17 untreated *** the 26 marmosets treated with-5 D,10 wore contact lenses 9 hrs/day without interruptions and were mea-sured at the end of 10 weeks of treatment(T10)and after 4 weeks of recovery(R14).Eight had both contact lenses removed for 30 mins twice/day(mid-morning and mid-afternoon)during the first four weeks of treatment(early interruption group)and eight had the lenses removed during the second four weeks of treatment(late interruption group).The two interruption groups were measured after 4,8 and 12 weeks of treatment only(T4,T8,T12).

关键词： removed treatment untreated

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血吸虫病中度流行区化疗对象筛查方案的研究

中国血吸虫病防治杂志 2002年第6期14卷 418-421页

作者：李军宏汪天平肖祥吴维铎吕大兵方国仁蔡伟郑江许静王蓉蓉中国预防疾病控制中心寄生虫病预防控制所上海200025 安徽省寄生虫病防治研究所安徽省当涂县血吸虫病防治站

目的　探讨血吸虫病中度流行区简便、有效、经济、适用的化疗对象筛查方案。方法　分别以粪检、询检、间接血凝法 (IHA)及胶体染料试纸条法 (CDSIA,目前改称 DDIA)对居民进行血吸虫病筛查 ,并对各方法进行分析和评价。结果　经比较分析 ... 详细信息

目的　探讨血吸虫病中度流行区简便、有效、经济、适用的化疗对象筛查方案。方法　分别以粪检、询检、间接血凝法 (IHA)及胶体染料试纸条法 (CDSIA,目前改称 DDIA)对居民进行血吸虫病筛查 ,并对各方法进行分析和评价。结果　经比较分析 ,IHA法在一些指标上优于其他方法 ,但每检出 1例病人的费用也高于其他方法。结合流行病学资料 ,本研究提出 3种 [A、B、C(包括 a,b两种情况 ) ]综合筛查方案 ,敏感性分别为 88.46%、80 .77%、82 .0 5 %和 92 .3 1% ;每检出 1例感染者所需费用分别为 8.5 3元、6.5 9元、8.78和 5 .97元。结论　 IHA经检验是一种简便、有效 ,在感染率为5 % -10 %的中度流行区较可取的筛查方法 ,但所需费用仍较高 ;DSIA较 IHA更为简便、快速、廉价 ,且敏感性高。各方法综合应用可提高检出率、降低成本。综合筛查方案 (Cb)具有减少工作量 ,降低漏检率 ,简便、经济。

关键词：血吸虫病询检法间接血凝法胶体染料试纸条法

Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma

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Frontiers of Medicine 2021年第2期15卷 275-291页

作者： Na Qin Yuancheng li Cheng Wang Meng Zhu Juncheng Dai Tongtong Hong Demetrius Albanes Stephen lam Adonina Tardon Chu Chen Gary Goodman Stig EBojesen Maria Teresa landi Mattias Johansson Angela Risch H-Erich Wichmann Heike Bickeboller Gadi Rennert Susanne Arnold Paul Brennan John KField Sanjay Shete loic le Marchand Olle Melander Hans Brunnstrom Geoffrey liu Rayjean JHung Angeline Andrew lambertus AKiemeney Shan Zienolddiny Kjell Grankvist Mikael Johansson Neil caporaso Penella Woll Philip lazarus Matthew BSchabath Melinda caldrich Victoria lStevens Guangfu Jin David CChristiani Zhibin Hu Christopher IAmos Hongxia Ma Hongbing Shen Department of Epidemiology Center for Global HealthSchool of Public HealthNanjing Medical UniversityNanjing 211166China State Key laboratory of Reproductive Medicine Center for Global HealthNanjing Medical UniversityNanjing 211166China Department of Bioinformatics School of Biomedical Engineering and InformaticsNanjing Medical UniversityNanjing 211166China Jiangsu Key lab of cancer Biomarkers Prevention and TreatmentCollaborative Innovation Center for Cancer MedicineNanjing Medical UniversityNanjing 211166China China International Cooperation Center for Environment and Human Health School of Public HealthNanjing Medical UniversityNanjing 211166China Division of cancer Epidemiology and Genetics National Cancer InstituteBethesdaMD 20892-9304USA Department of Integrative Oncology British Columbia Cancer AgencyVancouverBC V5Z 1L3Canada Faculty of Medicine University of Oviedo and CIBERESPOviedo 33006Spain Program in Epidemiology Public Health Sciences DivisionFred Hutchinson Cancer Research CenterSeattleWA 98109-1024USA Public Health Sciences Division Swedish Cancer InstituteSeattleWA 98026USA Department of Clinical Biochemistry Copenhagen University HospitalCopenhagen DK-1017Denmark National cancer Institute BethesdaMD 20892-9304USA Genetic Epidemiology Group International Agency for Research on CancerLyon 69372France cancer Center Cluster Salzburg at PlUS Department of Molecular BiologyUniversity of SalzburgHeidelberg 5020Austria Institute of Medical Informatics Biometry and EpidemiologyChair of EpidemiologyLudwig Maximilians UniversityMunichBavaria 80539Germany Department of Genetic Epidemiology University Medical Center GoettingenGoettingen 37075Germany Technion Faculty of Medicine Carmel Medical CenterHaifa 3448516Israel Markey cancer Center University of KentuckyLexingtonKY 40506-0054USA Department of Molecular and Clinical cancer Medicine Roy Castle Lung Cancer Research ProgrammeThe University of Liverpool Institute of Translational MedicineLiverpool L697Z

Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer(NSClC)risk,biological mechanisms of these variants remain largely *** integrating a large-scale genotype data of 15581 lung adenocarcinoma(AD)cases,8350 squamous cell carcinoma(SqCC)cases,and 27355 controls,as well as multiple transcriptome and epigenomic databases,we conducted histology-specific meta-analyses and functional annotations of both reported and novel susceptibility *** identified 3064 credible risk variants for NSClC,which were overrepresented in enhancer-like and promoter-like histone modification peaks as well as DNase I hypersensitive *** factor enrichment analysis revealed that USF1 was AD-specific while CREB1 was *** annotation and genebased analysis implicated 894 target genes,including 274 specifics for AD and 123 for SqCC,which were overrepresented in somatic driver genes(ER=1.95,P=0.005).Pathway enrichment analysis and Gene-Set Enrichment Analysis revealed that AD genes were primarily involved in immune-related pathways,while SqCC genes were homologous recombination deficiency *** results illustrate the molecular basis of both wellstudied and new susceptibility loci of NSClC,providing not only novel insights into the genetic heterogeneity between AD and SqCC but also a set of plausible gene targets for post-GWAS functional experiments.

关键词： lung cancer genome-wide association study function annotation immune homologous recombination repair deficiency genetic heterogeneity

ERCC1 and ERCC2 polymorphisms and risk of idiopathicazoospermia ina Chinese population

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南京医科大学学报(自然科学版) 2008年第10期 1244-1244页

作者： Ji, G. X. Gu, A. H. Xia, Y. K. lu, C. C. liang, J. Wang, S. l. Ma, J. Peng, Y. Z. Wang, X. R. Nanjing Med Univ, Key lab Reprod Med, Inst Toxicol, Nanjing 210029, Peoples R China. Nanjing Med Univ, Nanjing Matern & Child Hlth Hosp, Nanjing 210029, Peoples R China.

The ERCC1(excision repair cross complementation group 1) and ERCC2(excision repair cross complementation group 2) genes are important in repairing DNA damage and genomic instability in germ cells, and are essential for normal spermatogenesis. It has been verified that polymorphisms of these two genes could alter DNA repair capacity in some phenotypic studies. However, little information is available on these polymorphisms in male infertility. This study was designed to examine whether ERCC1 polymor- phisms 3 UTR(C8092A), Asn118Asn(G19007A) and ERCC2 polymorphisms Asp312Asn(G -> A), lys751Gln (A -> C), which have been reported to contribute to some cancers, are associated with idiopathic azoospermia in the Chinese population. The four polymorphisms were genotyped using polymerase chain reaction-restriction fragment length polymorphism assay in a hospital-based case-control study, comprising 202 infertile patients with idiopathic azoospermia and 187 fertile controls. It was found that the ER- CC1 8092 ca + AA genotypes were significantly associated with an increased risk of idiopathic azoospermia(OR = 1.750, 95% CI = 1.170-2.618), while other polymorphisms appeared to show no significant differences between cases and controls. Further studies are needed to confirm the roles of these polymorphisms in idiopathic azoospermia.

关键词： azoospermia DNA repair ERCC1 ERCC2 polymorphisms epair gene xpd male-infertility lung-cancer dnadamage etaanalysis association glioma cells assay men

Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage

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南京医科大学学报(自然科学版) 2008年第10期 1355-1355页

作者： cai, W. Y. Zhu, Y. Furuya, K. li, Z. Sokabe, M. Chen, l. Nanjing Med Univ, lab Reprod Med, Dept Physiol, Nanjing 210029, Jiangsu, Peoples R China. Nagoya Univ, Grad Sch Med, Dept Physiol, Nagoya, Aichi 4668550, Japan. JST, ICORP SORST Cell Mechanosensing, Nagoya, Aichi 4668550, Japan. Natl Inst Physiol Sci, Dept Mol Physiol, Okazaki, Aichi 4448585, Japan.

Herein, we show that a single injection of P4(4 mg/kg) at 1 h or 48 h, but not 96 h, before middle cerebral artery occlusion (McaO) produces significant protective effects against the ischemia-induced neuronal death and the deficits in spatial cognition and UP induction. The present study focused on the molecular mechanisms underlying the neuroprotection exerted by P4 administration at I h and 48 h pre-McaO, termed acute and delayed P4-neuroprotection, respectively. Pharmacology suggested that P4-receptor(P4R) cascading to a Src-ERK1/2 signaling mediated the delayed P4-neuroprotection. To support this, it was observed by anti-phosph-ERK1/2 immunoblots that a single injection of P4 triggered a P4R-mediated persistent increase in ERK1/2 phosphorylation and their nuclear translocation for 48 h. In contrast, the acute P4-neuroprotection did not depend on the P4R-mediated Src-ERK1/2 signaling. Instead, the acute P4-administration attenuated the NMDA-induced rise in the intracellular calcium concentration([ca2+] (i) ) that may be a primary cause for McaO-induced neuronal injury. This effect seemed to be exerted by an antagonism of sigma(1) receptor since the sigma(1) receptor antagonist NE100 perfectly mimicked the acute P4-neuroprotection and also attenuated the NM- DA-incluced [ca2+] (i), increase. These findings suggest that the P4 neuroprotection involves two independent processes depending on the timing of P4 administration before McaO: an acute protection by antagonizing sigma (1) receptor to inhibit NMDAr-ca2+ influx and a delayed one by an activation of P4R-mediated SrcERK signaling pathway. (C) 2008 Elsevier ltd. All rights reserved.

关键词： progesterone(P4) middle cerebral artery occlusion(McaO) extracellular receptor kinase(ERK) NMDA receptor (NMDAr) sigma1 (sigma (1) ) receptor cerebral-artery occlusion long-term potentiation methyl-d-aspartate preconditioning-induced activation cerebellar purkinje-cells hippocampal ca1 region rat hippocampus protein-kinase nmda receptor tyrosine phosphorylation

Immunity:研究开发出最优的HIV疫苗递送模式

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现代生物医学进展 2017年第27期17卷 I0003-I0003页

作者： Matthias Pauthner Colin Havenar-Daughton Devin Sok Joseph P. Nkolola Raiza Bastidas Archana V. Boopathy Diane G. carnathan Abishek Chandrashekar Kimberly M. Cirelli Christopher A. Cottrell Alexey M. Eroshkin Javier Guenaga Kirti Kaushik Daniel W. Kulp Jinyan liu laura E. McCoy Aaron l. Oom Gabriel Ozorowski Kai W. Post Shailendra K. Sharma Jon M. Steichen Steven W. de Taeye Talar Tokatlian Alba Torrents de la Peña Salvatore T. Butera Celia C. laBranche David C. Montefiori Guido Silvestri Ian A. Wilson Darrell J. Irvine Rogier W. Sanders William R. Schief Andrew B. Ward Richard T. Wyatt Dan H. Barouch Shane Crotty Dennis R. Burton University of california San Diego La Jolla CA 92093 USA

HIV已不再占据头条新闻。这主要是因为抗逆转录病毒药物的成功开发已将HIV病毒感染导致的艾滋病（AIDS）转化为一种慢性的可控制的疾病。然而。当前在全世界大约0．367亿名HIV感染者中，仅约一半的人能够获得控制这种病毒所需的药物。... 详细信息

HIV已不再占据头条新闻。这主要是因为抗逆转录病毒药物的成功开发已将HIV病毒感染导致的艾滋病（AIDS）转化为一种慢性的可控制的疾病。然而。当前在全世界大约0．367亿名HIV感染者中，仅约一半的人能够获得控制这种病毒所需的药物。与此同时。新的HIV感染率持续保持在非常高的水平，这突出强调了需要开发一种预防性疫苗。然而，几十年来。

关键词： HIV感染者研究开发疫苗递送病毒感染逆转录病毒艾滋病感染率

Observatory science with eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 97-138页

作者： Jean J.M.in 't Zand Enrico Bozzo Jinlu Qu Xiang-Dong li lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano Jean-luc Atteia Nils A.andersson M.Cristina Baglio David R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous Pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini luciano Burderi Edward M.cackett Riccardo campana Sergio campana Piergiorgio casella Yuri cavecchi Frank Chambers liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga Xilong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti Duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa luca Izzo long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai laurens Keek Stefanie Komossa Ingo Kreykenbohm lucien Kuiper Devaky Kunneriath Gang li En-Wei liang Manuel linares Francesco longo FangJun lu Alexander A.lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez Roberto P.Mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria Peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig SRON Netherlands Institute for Space Research Department of Astronomy University of Geneva Key laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences School of Astronomy and Space Science Nanjing University INAF-IASF Bologna ASI Via del Politecnico snc INAF-Istituto di Astrofisica e Planetologie Spaziali Institut für Astronomie und Astrophysik Tübingen Universit?t Tübingen NASA Goddard Space Flight Center ICREA&Institute of Space Sciences(IEEC-CSIC) Campus UABCarrer de Can Magrans CSPAR SPA University of Alabama in Huntsville Department of Physics Texas Tech University INAF Osservatorio Astronomico di capodimonte leiden Observatory Leiden University Anton Pannekoek Institute University of Amsterdam ASTRON Netherlands Institute for Radio Astronomy Universitat Politecnica de catalunya(UPC-IEEC) Universitádegli Studi di Urbino‘ca.lo Bo’ Max-Planck-Institut für Radioastronomie Dr.Karl-Remeis-Sternwarte and Erlangen Centre for Astroparticle Physics(EcaP) Friedrich Alexander Universit?t Erlangen-Nurnberg Purple Mountain Observatory Chinese Academy of Sciences Instituto de Astrofysíca de Andalucia-CSIC Department of Physics and Astronomy University of Southampton IRAP Universitéde ToulouseCNRSUPSCNES Mathematical Sciences and STAG Research Centre University of Southampton New York University Abu Dhabi Center for Relativistic Astrophysics School of PhysicsGeorgia Institute of Technology Physics Department Middle East Technical University Department of Physics Technion-Israel Institute of Technology INAF Osservatorio Astronomico di Brera Tata Institute of Fundamental Research Dipartimento di Matematica e Fisica Universitàdegli Studi Roma Tre Instituto de Astrofísica de canarias Instituto Nacional de Pesquisas Espaciais-INPE National Space Institute Technical University of Denmark(DTU Space) Department of Physics and Astronomy Michigan State University INAF Osservatorio Astrofisico di Arcetri Dipartimento di Fisica Universitádegli Studi di Cagliari Department of Physics and A

In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s.

关键词： space research in struments nuclear astrophysics flare stars accretion and accretion disks mass loss and stellar winds cataclysmic binaries X-ray binaries supernova remnants active galactic nuclei X-ray bursts gamma-ray bursts gravitational waves

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生态环境曲面建模基本定理及其应用

中国科学：地球科学 2020年第8期50卷 1083-1105页

作者：岳天祥赵娜刘羽王轶夫张斌杜正平范泽孟史文娇陈传法赵明伟宋敦江王世海宋印军闫长青李启权孙晓芳张丽丽田永中王薇王英安马胜男黄宏胜卢毅敏王情王晨亮王玉柱鹿明周伟刘熠尹笑哲王宗包正义赵苗苗赵亚鹏焦毅蒙 Ufra NASEER 范斌李赛博杨阳 John P.WIlSON 中国科学院地理科学与资源研究所资源与环境信息系统国家重点实验室北京100101 中国科学院大学资源与环境学院北京100149 江西农业大学国土资源与环境学院南昌330045 山东科技大学测绘科学与工程学院青岛266590 北京林业大学林学院北京100083 西华师范大学国土资源学院南充637002 滁州学院地理信息与旅游学院滁州239000 中国科学院科技战略咨询研究院北京100190 山东科技大学信息工程系青岛266590 四川农业大学资源学院成都611130 曲阜师范大学地理与旅游学院日照276828 中国科学院空天信息创新研究院北京100094 西南大学地理科学学院重庆400715 国家减灾中心卫星遥感部北京100721 中国人口与发展研究中心人口数据部北京100081 国家标准化管理委员会工业二部北京100088 福州大学数字中国研究院福州350002 中国疾病预防控制中心环境与健康相关产品安全所北京100021 中国地质大学(北京)信息工程学院北京100083 钱学森空间技术实验室北京100094 重庆交通大学建筑与城市规划学院重庆400074 江苏省地理信息资源开发与利用协同创新中心南京210023 Spatial Sciences Institute University of Southern CaliforniaLos AngelesCA 90089-0374USA

在高精度曲面建模方法和地球表层系统建模基本定理研究结果基础上,演绎提出了生态环境曲面建模基本定理.以京津冀地区为案例,对基于生态环境曲面建模基本定理的空间升尺度、空间降尺度、空间插值、数据融合和模型-数据同化等算法进行了... 详细信息

在高精度曲面建模方法和地球表层系统建模基本定理研究结果基础上,演绎提出了生态环境曲面建模基本定理.以京津冀地区为案例,对基于生态环境曲面建模基本定理的空间升尺度、空间降尺度、空间插值、数据融合和模型-数据同化等算法进行了实证研究,与传统算法精度进行了比较分析.结果表明,由于基于生态环境曲面建模基本定理的各种算法综合了外蕴量信息和内蕴量信息,同时运用了理论上完善的信息综合方法,使海拔高度曲面的升尺度均方根误差至少降低了9m,年平均气温未来情景的降尺度精度至少提高16%,年平均气温过去变化趋势的数据融合精度至少提高70%,年平均降雨量过去变化趋势的空间插值精度至少提高0.2%,碳储量的模型-数据同化精度提高了40%.文章最后讨论了生态曲面建模基本定理亟待解决的五大理论问题和四大应用基础问题.

关键词：高精度曲面建模生态环境曲面建模基本定理空间升尺度空间降尺度空间插值数据融合模型-数据同化模型耦合