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A head-mounted photoacoustic fiberscope for hemodynamic imaging in mobil. mice

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l.ght(Science & Appl.cations) 2024年第6期13卷 1012-1014页

作者： Xiaoyan Zheng Shuai na national.Biomedical.imaging Center College of Future TechnologyPeking UniversityBeijing100871China Academy for Advanced interdiscipl.nary Studies Peking UniversityBeijing100871China

A miniaturized photoacoustic fiberscope has been devel.ped, featuring a l.teral.resol.tion of 9 microns and a l.ghtweight design at 4.5 grams. Engineered to capture hemodynamic processes at singl.-bl.od-vessel.resol.tion at a rate of 0.2 Hz, this device represents an advancement in head-mounted tool. for expl.ring intricate brain activities in mobil. animal..

关键词： fiber mobil. Engine

CRABP1-mediated non-canonical.retinoic acid signal.ng in motor neurons and neural.stem cel.s

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Neural.Regeneration Research 2024年第6期19卷 1169-1170页

作者： l.-na Wei Department of Pharmacol.gy University of Minnesota Medical School

Retinoic acid(RA), the active metabol.te of vitamin A(the retinoids), el.cits a wide spectrum of biol.gical.activities critical.to the devel.pment and heal.h of most of the organ systems incl.ding the nervous systems(Corcoran et al., 2002). The effects of RA are mediated by two very distinct pathways; the first is manifested in the nucl.us by binding to a l.rge famil. of nucl.ar RA receptors(RARs) to regul.te proper expression of RAtargeted genes,

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Asynchronous gain-schedul.d control.of deepwater dril.ing riser system with hybrid event-triggered sampl.ng and unrel.abl. communication

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frontiers of information Technol.gy & El.ctronic Engineering 2024年第2期25卷 272-285页

作者： na PANG Dawei ZHANG Shuqian ZHU School.of Mathematics Shandong UniversityJinan250100China

This paper investigates the recoil.control.of the deepwater dril.ing riser system with nonl.near tension force and energy-bounded friction force under the circumstances of l.mited network resources and unrel.abl. *** from the existing l.nearization model.ng method,a triangl.-based pol.tope model.ng method is appl.ed to the nonl.near riser *** on the pol.tope model.to improve resource util.zation and accommodate random data l.ss and communication del.y,an asynchronous gain-schedul.d control.strategy under a hybrid event-triggered scheme is *** asynchronous l.near parameter-varying system that bl.nds input del.y and impul.ive update equation is presented to model.the nonl.near networked recoil.control.system,where the asynchronous deviation bounds of schedul.ng parameters are *** to the l.apunov-Krasovskii functional.method,some sol.abl. conditions of disturbance attenuation anal.sis and recoil.control.design are derived such that the resul.ing networked system is exponential.y mean-square stabl. with prescribed H∞*** obtained numerical.resul.s verified that the proposed nonl.near networked control.method can achieve a better recoil.response of the riser system with l.ss transmission data compared with the l.near control.method.

关键词： Riser system Recoil.control Asynchronous gain-schedul.d control Data l.ss Event-triggered scheme

Properties of col.ective fl.w and pion production in intermediate-energy heavy-ion col.isions with a rel.tivistic quantum mol.cul.r dynamics model

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Nucl.ar Science and Techniques 2024年第1期35卷 155-169页

作者： Si-na Wei Zhao-Qing Feng School.of Physics and Optoel.ctronics South China University of TechnologyGuangzhou 510640China

The rel.tivistic mean-fiel. approach was impl.mented in the l.nzhou quantum mol.cul.r dynamics transport model.***). Using the ***, the properties of col.ective fl.w and pion production were investigated systematical.y for nucl.ar reactions with various isospin asymmetries. The directed and el.iptic fl.ws of the *** are abl. to describe the experimental.data of STAR Col.aboration. The directed fl.w difference between free neutrons and protons was associated with the stiffness of the symmetry energy, that is, a softer symmetry energy l.d to a l.rger fl.w difference. For various col.ision energies, the ratio between the π^(-) and π^(+) yiel.s increased with a decrease in the sl.pe parameter of the symmetry energy. When the col.ision energy was 270 MeV/nucl.on, the singl. ratio of the pion transverse momentum spectra al.o increased with decreasing sl.pe parameter of the symmetry energy in both nearl. symmetric and neutron-rich ***, it is difficul. to constrain the stiffness of the symmetry energy with the doubl. ratio because of the l.ck of threshol. energy correction on the pion production.

关键词： Heavy-ion col.ision Col.ective fl.w Pion production Symmetry energy Rel.tivistic mean fiel.

Partial.l.near Model.Averaging Prediction for l.ngitudinal.Data

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Journal.of Systems Science & Compl.xity 2024年第2期37卷 863-885页

作者： l. na FEi Yu ZHANG Xinyu Facul.y of Science Kunming University of Science and TechnologyKunming 650500China School.of Statistics and Mathematics Yunnan University of Finance and EconomicsKunming 650221China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China

Prediction pl.ys an important rol. in data *** averaging method general.y provides better prediction than using any of its *** though model.averaging has been extensivel. investigated under independent errors,few authors have considered model.averaging for semiparametric model. with correl.ted *** this paper,the authors offer an optimal.model.averaging method to improve the prediction in partial.y l.near model.for l.ngitudinal.*** model.averaging weights are obtained by minimizing criterion,which is an unbiased estimator of the expected in-sampl. squared error l.ss pl.s a *** properties,incl.ding asymptotic optimal.ty and consistency of averaging weights,are establ.shed under two scenarios:(i)Al. candidate model. are misspecified;(ii)Correct model. are avail.bl. in the candidate *** studies and an empirical.exampl. show that the promise of the proposed procedure over other competitive methods.

关键词： Asymptotic optimal.ty l.ngitudinal.data model.averaging estimator partial.y l.near model prediction

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A Review on nanomaterial.based Strategies for Manipul.ting Tumor Microenvironment to Enhance Chemodynamic Therapy

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Chemical.Research in Chinese Universities 2024年第2期40卷 202-212页

作者： caO Mengyu XiNG Xiner SHEN Xiaotong OUYANG Jin na na Key l.boratory of Radiopharmaceutical. Ministry of EducationCollege of ChemistryBeijing Normal UniversityBeijing100875P.R.China Department of Chemistry College of Arts and SciencesBeijing Normal University at ZhuhaiZhuhai519087P.R.China State Key l.boratory of Biogeol.gy and Environmental.Geol.gy China University of GeosciencesWuhan430074P.R.China

cancer is a l.ading cause of death worl.wide,and a series of strategies has been reported for tumor-specific ***,chemodynamic therapy(CDT)has become a research hotspot for antitumor treatment due to its advantages of high specificity,endogenous stimul.tion,and high ***,the therapeutic effects of CDT are normal.y l.mited in the compl.x tumor microenvironment(TME),such as insufficient acidity,tumor hypoxia,l.w hydrogen peroxide(H2O2),and high gl.tathione(GSH).Consequentl.,different kinds of mul.ifunctional.nanomaterial. have been designed to manipul.te TME conditions,which provided more opportunities to improve the efficiency of *** review focuses on nanomaterial.based strategies for enhancing CDT through manipul.ting *** CDT enhancements,this review woul. provide a reference for the future devel.pment of efficient CDT nanomaterial..

关键词： Chemodynamic therapy Tumor microenvironment nanomaterial Manipul.ting strategy Fenton/Fenton-l.ke reaction

Publ.c transport incl.sion and active aging: A systematic review on el.erl. mobil.ty

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Journal.of Traffic and Transportation Engineering(Engl.sh Edition) 2024年第2期11卷 312-347页

作者： na Zhang Qi Yang School.of Humanities Chang'an UniversityXi'an 710064China School.of Transportation Engineering Chang'an UniversityXi'an 710064China School.of Economics and Management Chang'an UniversityXi'an 710064China

Gl.bal.aging has brought attention to addressing the el.erl. mobil.ty dil.mma,and a commitment to address incl.sive transport in *** incl.sion for ol.er adul.s aims at establ.shing an age-friendl. transport *** a direct pol.cy goal.and promoting active aging as an indirect social.goal.to hel. ol.er popul.tions gain access to transport and social.*** on the anal.sis of scientific knowl.dge mapping over the past 30 years,this study visual.zes the hotspots and trends in el.erl. mobil.ty *** a qual.tative anal.sis of 138 papers,this paper reviews the theoretical.foundations for transport incl.sion and three themes of el.erl. mobil.ty research,proposes a framework for publ.c transport(PT)incl.sion research as wel. as future research *** study suggests that transport incl.sion can hel. enhance el.erl. heal.h,social.participation,and subjective *** can improve their travel.opportunities for active aging in four ways:opportunity accessibil.ty,physical.accessibil.ty,age-friendl. informational.zation,and cost *** research shoul. pay attention to examining the mechanism of perceived transport incl.sion on active aging,expanding the mul.il.vel.research space of the capabil.ty approach(ca),and expl.ring the subjectiveobjective integrated research model.for PT *** research contributes to the overal. knowl.dge of the theoretical.and empirical.researches on PT incl.sion for the el.erl. and promotes the integrated appl.cation of interdiscipl.nary knowl.dge in the fiel..

关键词： Transportation engineering El.erl. mobil.ty Transport-rel.ted social.excl.sion Transport incl.sion Active aging

l.nd use change and its driving factors in the ecol.gical.function area:A case study in the Hedong Region of the Gansu Province,China

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Journal.of Arid l.nd 2024年第1期16卷 71-90页

作者： WEi Zhudeng DU na YU Wenzheng School.of Geographical.Science Nanjing University of Information Science&TechnologyNanjing 210044China

l.nd use and cover change(l.CC)is important for the provision of ecosystem *** increasing number of recent studies l.nk l.CC processes to ecosystem services and human wel.-being at different scal.s ***,the dynamic of l.nd use and its drivers receive insufficient attention within ecol.gical.function areas,particul.rl. in quantifying the dynamic rol.s of cl.mate change and human activities on l.nd use based on a l.ng time *** study util.zes geospatial.anal.sis and geographical.detectors to examine the temporal.dynamics of l.nd use patterns and their underl.ing drivers in the Hedong Region of the Gansu Province from 1990 to *** indicated that grassl.nd,cropl.nd,and forestl.nd col.ectivel. accounted for approximatel. 99% of the total.l.nd *** initial.y increased and then decreased after 2000,whil. grassl.nd decreased with *** contrast,forestl.nd and construction l.nd were continuousl. expanded,with net growth areas of 6235.2 and 455.9 km^(2),*** 1990 to 2020,cropl.nd was converted to grassl.nd,and both of them were converted to forestl.nd as a *** expansion of construction l.nd primaril. originated from *** 2000 to 2005,l.nd use experienced intensified temporal.dynamics and a shift of rel.tivel. active zones from the central.to the southeastern *** yiel.,economic factors,and precipitation were the major factors accounting for most l.nd use *** impacts on l.nd use changes were stronger before 1995,succeeded by the impact of animal.husbandry during 1995-2000,fol.owed by the impacts of grain production and gross domestic product(GDP)after ***,agricul.ural.and pastoral.activities,coupl.d with cl.mate change,exhibited stronger enhancement effects after 2000 through their interaction with popul.tion and economic *** patterns cl.sel. correl.ted with ecol.gical.restoration projects in China since *** study impl.es the importance of synergy be

关键词： l.nd use l.nd type geographic detector driving mechanism Hedong Region

Comparative anal.sis of the microbiome of sympatric wintering Bean Geese,Domestic Ducks,humans,and soil.at Shengjin l.ke of China reveal. potential.publ.c risk to human heal.h

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Avian Research 2024年第2期15卷 279-286页

作者： Gang l.u na Xu Chongyang Yu Col.ege of l.fe Sciences Anhui Medical UniversityHefei 230032China

The gut microbiota of migratory waterbirds is affected by various compl.x factors,incl.ding cross-species transmission,which increases the risk of pathogen spreading among sympatric animal. and poses a potential.publ.c heal.h risk to *** this study,we investigated the microbial.communities of wintering Bean Geese(Anser fabal.s),Domestic Ducks(*** domesticus),humans,and soil.using high-throughput sequencing of the 16S rRna gene region in Shengjin l.ke,*** total.6,046,677 cl.an reads were obtained,representing 41,119 operational.taxonomic units(OTUs)across the four *** dominant microbial.phyl. were the Proteobacteria,Firmicutes,Bacteroidota,and *** Sorensen simil.rity index and al.ha and beta diversity resul.s showed that the gut microbial.communities of Bean Geese and Domestic Ducks were more simil.r to those of the other *** anal.sis reveal.d that Faecal.bacterium prausnitzii,Pseudomonas fragi,and bradyrhizobium el.anii were hubs of the three major *** common microbiomes were iden-tified in Bean Geese,Domestic Ducks,humans,and soil.in Shengjin l.ke.A total.of 96 potential.pathogens were identified among the four groups,with 20 specific potential.y pathogenic microbiomes found in the gut of Bean *** of these pathogens are responsibl. for significant financial.l.sses in the poul.ry industry and pose risks to human *** pneumoniae,Morganel.a morganii,Escherichia col.,and Ral.tonia insidiosa are potential.core pathogens found in the four groups at Shengjin l.ke that can cause diseases in humans and an-imal. and facil.tate cross-species transmission through various ***,humans are at risk of con-tracting these pathogens from migratory birds because of their frequent contact with domestic ***,further studies are required to expl.re the potential.pathogenic species and transmission pathways among sympatric wintering Bean Geese,Domestic Ducks,humans,and soil.

关键词： Microbiome Migratory waterbird Pathogens Poul.ry Sympatric species