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Serum proteins differentially expressed in gestational diabetes mellitus assessed using isobaric tag for relative and absolute quantitation proteomics

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World Journal of Clinical Cases 2024年第8期12卷 1395-1405页

作者： wei-Li Cao cui-Ping Yu Ling-Li Zhang Department of Women’s Health Care Maternal and Child Health Hospital of Hubei ProvinceWuhan 430070Hubei ProvinceChina Obstetrical Department The First People’s Hospital of Jiangxia District Wuhan City(Union Jiangnan Hospital Huazhong University of Science and Technology)Wuhan 430200Hubei ProvinceC Department of Gynecology Maternal and Child Health Hospital of Hubei ProvinceWuhan 430070Hubei ProvinceChina

BACKGROUND As a well-known fact to the public,gestational diabetes mellitus(GDM)could bring serious risks for both pregnant women and *** this important investigation into the linkage between GDM patients and their altered expression in the serum,proteomics techniques were deployed to detect the differentially expressed proteins(DEPs)of in the serum of GDM patients to further explore its pathogenesis,and find out possible biomarkers to forecast GDM *** Subjects were divided into GDM and normal control groups according to the IADPSG diagnostic *** samples were randomly selected from four cases in each group at 24-28 wk of gestation,and the blood samples were identified by applying iTRAQ technology combined with liquid chromatography-tandem mass *** proteins and signaling pathways associated with GDM were identified by bioinformatics analysis,and the expression of key proteins in serum from 12 wk to 16 wk of gestation was further verified using enzyme-linked immunosorbent assay (ELISA).RESULTS Forty-seven proteins were significantly differentially expressed by analyzing the serum samples between the GDMgravidas as well as the healthy ones. Among them, 31 proteins were found to be upregulated notably and the rest16 proteins were downregulated remarkably. Bioinformatic data report revealed abnormal expression of proteinsassociated with lipid metabolism, coagulation cascade activation, complement system and inflammatory responsein the GDM group. ELISA results showed that the contents of RBP4, as well as ANGPTL8, increased in the serumof GDM gravidas compared with the healthy ones, and this change was found to initiate from 12 wk to 16 wk *** GDM symptoms may involve abnormalities in lipid metabolism, coagulation cascade activation, complementsystem and inflammatory response. RBP4 and ANGPTL8 are expected to be early predictors of GDM.

关键词： Gestational diabetes mellitus Liquid chromatography-tandem mass spectrometry Isobaric tag for relative and absolute quantitation Proteomics Biomarker

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Sensing-Assisted Accurate and Fast Beam Management for Cellular-Connected mmWave UAV Network

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China Communications 2024年第6期21卷 271-289页

作者： cui Yanpeng Zhang Qixun Feng Zhiyong Qin Wen Zhou Ying wei Zhiqing Zhang Ping School of Information and Communication Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China School of Computer Science Northwestern Polytechnical UniversityXi’an 710072China

Beam management,including initial access(IA)and beam tracking,is essential to the millimeter-wave Unmanned Aerial Vehicle(UAV)***,the conventional communicationonly and feedback-based schemes suffer a high delay and low accuracy of beam alignment,since they only enable the receiver to passively“hear”the information of the transmitter from the radio *** paper presents a novel sensing-assisted beam management approach,the first solution that fully utilizes the information from the visual domain to improve communication *** employ both integrated sensing and communication and computer vision techniques and design an extended Kalman filtering method for beam tracking and ***,we also propose a novel dual identity association solution to distinguish multiple UAVs in dynamic ***-world experiments and numerical results show that the proposed solution outperforms the conventional methods in IA delay,association accuracy,tracking error,and communication performance.

关键词： beam management integrated sensing and communication UAV communication

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Research on Recommendation Algorithms Based on Cloud Models in Probabilistic Linguistic Environments

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Journal of Systems Science and Information 2024年第1期12卷 96-112页

作者： Peng YANG Xifeng MA Meng wei Chunsheng cui Libin CHE College of Computer and Information Engineering Henan University of Economics and LawZhengzhou 450046China

To solve the problem that the traditional cloud model can't directly process the textual review information in the recommendation algorithm,this paper combines the merits of the cloud model in transforming qualitative and quantitative knowledge with the multi-granularity advantages of probabilistic linguistic term sets in representing uncertain information,and proposes a recommendation algorithm based on cloud model in probabilistic language ***,this paper quantifies the attributes in the review text based on the probabilistic linguistic term ***,the maximum deviation method is used to determine the weight of each attribute in the evaluation information of the product to be recommended,and the comprehensive evaluation number and attribute weight are converted into the digital characteristic value of the cloud model by using the backward cloud ***,the products are recommended and sorted based on the digital characteristic value of the cloud *** algorithm is applied to the recommendation of 10 hotels,and the results show that the method is effective and practical,enriching the application of cloud models in the recommendation field.

关键词： recommendation algorithm cloud model probabilistic linguistic term set text reviews

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A review on electrocatalytic CO_(2) conversion via C-C and C-N coupling

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Carbon Energy 2024年第2期6卷 167-194页

作者： Zhuangzhi Zhang Sijun Li zheng Zhang Zhou Chen Hua Wang Xianguang Meng Wenquan cui Xiwei Qi Jiacheng Wang Hebei Provincial Laboratory of Inorganic Nonmetallic Materials College of Materials Science and EngineeringNorth China University of Science and TechnologyTangshanChina Key Laboratory of Luminescence Analysis and Molecular Sensing Ministry of EducationCollege of Chemistry and Chemical EngineeringSouthwest UniversityChongqingChina State Key Laboratory of New Textile Materials and Advanced Processing Technologies Hubei Key Laboratory of Biomass Fibers and Eco-Dyeing and FinishingCollege of Chemistry and Chemical EngineeringWuhan Textile UniversityWuhanChina College of Materials Xiamen UniversityXiamenChina Hebei Iron and Steel Laboratory TangshanChina Hebei Key Laboratory for Environment Photocatalytic and Electrocatalytic Materials College of Chemical EngineeringNorth China University of Science and TechnologyTangshanChina College of Metallurgy and Energy North China University of Science and TechnologyTangshanChina State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghaiChina Institute of Electrochemistry School of Materials Science and EngineeringTaizhou UniversityTaizhouChina

Electrochemical C-C and C-N coupling reactions with the conversion of abundant and inexpensive small molecules,such as CO_(2) and nitrogencontaining species,are considered a promising route for increasing the value of CO_(2) reduction *** development of high-performance catalysts is the key to the both electrocatalytic *** this review,we present a systematic summary of the reaction systems for electrocatalytic CO_(2) reduction,along with the coupling mechanisms of C-C and C-N bonds over outstanding electrocatalytic materials recently *** key intermediate species and reaction pathways related to the coupling as well as the catalyst-structure relationship will be also discussed,aiming to provide insights and guidance for designing efficient CO_(2) reduction systems.

关键词： C-C coupling C-N coupling CO_(2) conversion electrocatalysis urea synthesis

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Severe fever with thrombocytopenia syndrome virus infection attributed to cat contact:A case report in Beijing,China

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Virologica Sinica 2024年第3期39卷 513-515页

作者： Shuo Zhang Yu Leng Fa-Xue Zhang Bo-Kang Fu Bing-zheng Wu Jia-Hao Chen Ning cui Ning Zhao wei Liu Hao Li College of Life Sciences Southwest Forestry UniversityKunming650224China State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and EpidemiologyBeijing Key Laboratory of Vector Borne and Natural Focus Infectious DiseasesBeijing100071China School of Public Health Wuhan UniversityWuhan430071China The First Affiliated Hospital of Anhui Medical University Hefei230022China Xinyang 154 Hospital Xinyang464000China

Dear Editor,Severe fever with thrombocytopenia syndrome(SFTS)is an emerging tick-borne infectious disease caused by a novel bunyavirus called SFTS virus(SFTSV).It was initially identified in China in 2009(Yu et al.,2011).Since then,the number of reported SFTS cases has rapidly increased in China,South Korea,and Japan(Li,et al.,2018;Takahashi et al.,2014;Kim et al.,2018).Sporadic SFTS cases have also been identified in several other Asian countries,such as Vietnam,Pakistan,Myanmar,and Thailand(Takahashi et al.,2014;Tran et al.,2019;Li et al.,2021).This disease is recognized as a highly lethal viral hemorrhagic fever with a mortality rate ranging from 12%to 50%(Yu et al.,2011;Li et al.,2018;Takahashi et al.,2014;Kim et al.,2013).SFTS primarily spreads to humans through bites from ticks infected with SFTSV,with the Haemaphysalis longicornis tick acting as the predominant vector for SFTSV(Zhuang et al.,2018).

关键词： attributed initially predominant

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Atypical cervical spondylotic radiculopathy resulting in a hypertensive emergency during cervical extension: A case report and review of literature

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World Journal of Orthopedics 2024年第10期15卷 981-990页

作者： Hao-Cheng cui zheng-Qi Chang Shao-Ke Zhao Department of Orthopedic Surgery 960th Hospital of PLAJinan 250031Shandong ProvinceChina

BACKGROUND Extensive research revealed the absence of reports documenting hypertensive emergencies precipitated by changes in the cervical spine *** SUMMARY We here present a 57-year-old woman diagnosed as having cervical spondylotic radiculopathy(CSR)who was scheduled for anterior cervical decompression and *** post-anesthetic positioning,a sudden hypertensive surge was observed when the patient was in a supine position with the neck being slightly *** surge was promptly reversed through cervical flexion and head *** event however required an alternate surgical approach for recovery—posterior laminoplasty and endoscopy-assisted nucleus pulposus *** the 6-month outpatient follow-up period,cervical flexion and extension activities substantially improved in the patient without any episodes of increase in acute blood *** Maintaining a safe hypotensive posture and performing rapid,thorough deco-mpression surgery may serve as effective interventions for patients presenting symptoms similar to those of CSR accompanied by hypertensive emergencies(HE).This would mitigate the underlying causes of these HEs.

关键词： Atypical cervical spondylotic radiculopathy Hypertensive emergency Supine position Endoscopic-assisted Case report

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Tailored multifunctional hydrazine derivatives for efficient printable hole-conductive-free mesoscopic perovskite solar cells via enhancing defect passivation

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Journal of Energy Chemistry 2024年第8期95卷 357-363,I0008页

作者： Minghao Xia Ziwei zheng Yanjie Cheng Chaoyang Wang Zhaozhen cui Guodong Zhang Jinwei Gonga Anyi Mei Hongwei Han Michael Grätzel Center for Mesoscopic Solar Cells Wuhan National Laboratory for OptoelectronicsKey Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of EducationHuazhong University of Science and TechnologyWuhan 430074HubeiChina Key Laboratory of Flexible Electronics(KLoFE)&Institute of Advanced Materials(IAM) School of Flexible Electronics(Future Technologies)Nanjing Tech University(NanjingTech)Nanjing 211816JiangsuChina

The low-cost and easy large-scale fabrication advantages of printable mesoscopic perovskite solar cells(p-MPSCs)are overshadowed by their limited photovoltaic conversion efficiency(PCE).Here,we introduce the hydrazide derivative of 4-Hydroxybenzoylhydrazine(4-HBH)to improve the PCE of p-MPSCs by inducing enhanced defect *** carbonyl and hydrazine groups in hydrazide groups present strong interaction with *** hydroxyl group,as an electron donor group,increases the electron cloud density of the hydrazide group in 4-HBH under the conjugation of the benzene ring,and thus enhances its interaction with ***,the hydroxy group itself interacts with perovskite and passivates defects *** hydrazine agents can also reduce I2and suppress the loss of iodine in perovskite films,which inhibits the formation of iodine-related ***,p-MPSCs with 4-HBH achieve a high PCE of 19.21%,and present well improved stability.

关键词： Printable mesoscopic perovskite solar cells Multifunctional hydrazine derivatives Cooperative coordination Conjugation redox activity

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Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis

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Science China(Life Sciences) 2024年第5期67卷 865-878页

作者： wei Jia Yitao Li Kenneth C.P.Cheung Xiaojiao zheng School of Chinese Medicine Hong Kong Baptist UniversityHong KongChina Center for Translational Medicine and Shanghai Key Laboratory of Diabetes Mellitus Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University School of MedicineShanghai 200233China

Bile acids(BAs)play a crucial role in nutrient absorption and act as key regulators of lipid and glucose metabolism and immune *** the enterohepatic circulation,BAs are synthesized,metabolized,and reabsorbed,with a portion entering the vascular circulation and distributing *** allows BAs to interact with receptors in all major organs,leading to organ-organ interactions that regulate both local and global metabolic processes,as well as the immune *** review focuses on the whole-body effects of BA-mediated metabolic and immunological regulation,including in the brain,heart,liver,intestine,eyes,skin,adipose tissue,and *** BA synthesis and receptor signaling is a promising strategy for the development of novel therapies for various diseases throughout the body.

关键词： bile acid whole body metabolism immunity

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Optical Extinctions of Inter-Arm Molecular Clouds in M31:A Pilot Study for the Upcoming CSST Observations

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Research in Astronomy and Astrophysics 2024年第6期24卷 323-333页

作者： Cailing Chen zheng zheng Chao-wei Tsai Sihan Jiao Jing Tang Jingwen Wu Di Li Yun zheng Linjing Feng Yujiao Yang Yuan Liang National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Radio Astronomy and Technology Chinese Academy of SciencesBeijing 100101China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Zhejiang Lab Hangzhou 311121China

Recent submillimeter dust thermal emission observations have unveiled a significant number of inter-arm massive molecular clouds in ***,the effectiveness of this technique is limited to its sensitivity,making it challenging to study more distant *** study introduces an alternative approach,utilizing optical extinctions derived from space-based telescopes,with a focus on the forthcoming China Space Station Telescope(CSST).We first demonstrate the capability of this method by constructing dust extinction maps for 17 inter-arm massive molecular clouds in M31 using the Panchromatic Hubble Andromeda Treasury *** analysis reveals that inter-arm massive molecular clouds with an optical extinction(A_(V)) greater than 1.6 mag exhibit a notable A_(V) excess,facilitating their *** majority of these inter-arm massive molecular clouds show an A_(V) around 1 mag,aligning with measurements from our JCMT *** validation using a mock CSST RGB star catalog confirms the method's *** show that the derived A_(V)values using CSST z and y photometries align more closely with the input *** clouds with A_(V)> 1.6 mag can also be identified using the CSST mock *** thus claim that future CSST observation clouds provide an effective way for the detection of inter-arm massive molecular clouds with significant optical extinction in nearby galaxies.

关键词： infrared:stars ISM:clouds Galaxy:structure

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The influence of patterned microporous layer on the proton exchange membrane fuel cell performances

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Nano Research 2024年第7期17卷 6095-6101页

作者： Shunzhong Wang Kadi Hu wei Chen Yali Cao Linan Wang Zhichang Wang Lirui cui Mingzheng Zhou wei Zhu Hui Li Zhongbin Zhuang State Key Lab of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China State Power Investment Corporation Hydrogen Energy Company Ltd.Beijing 102600China Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical TechnologyBeijing 100029China Beijing Key Laboratory of Energy Environmental Catalysis Beijing University of Chemical TechnologyBeijing 100029China

The ordered membrane electrode assembly(MEA)has gained much attention because of its potential in improving mass ***,a comprehensive study was conducted on the influence of the patterned microporous layer(MPL)on the proton exchange membrane fuel cell *** patterned MPL is employed,grooves are generated between the catalyst layer and the gas diffusion *** is found that the grooves do not increase the contact resistance,and it is beneficial for water *** the MEA works under low humidity scenarios,the MEA with patterned MPL illustrated higher performance,due to the reduced inner resistance caused by improved water retention,leading to increased ionic ***,when the humidity is higher than 80%or working under high current density,the generated water accumulated in the grooves and hindered the oxygen mass transport,leading to a reduced MEA performance.

关键词： microporous layer patterned proton exchange membrane fuel cell mass transport humidity water reduction

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