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Accurate diagnosis of severe coronary stenosis based on resting magnetocardiography: a prospective, single-center, cross-sectional analysis

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Journal of Geriatric Cardiology 2024年第4期21卷 407-420页

作者： Jian-Guo cui Feng TIAN Yu-Hao MIAO Qin-hua JIN Ya-Jun SHI Li LI Meng-Jun SHEN Xiao-Ming XIE Shu-Lin ZHANG Yun-Dai CHEN School of Medicine Nankai UniversityTianjinChina Senior Department of Cardiology the Sixth Medical CenterChinese PLA General HospitalBeijingChina Joint Laboratory of Bioimaging Technology and Applications SAS-SIM-IT&MEDIShanghaiChina Shanghai Institute of Microsystem and Information Technology Chinese Academy of SciencesShanghaiChina

OBJECTIVE To evalu ate the role of resting magnetocardiography in identifying seve re coronary artery stenosis in patients with suspected coronary artery *** A total of 513 patients with angina symptoms were included and divided into two groups based on the extent of coronary artery disease determined by angiography:the non-severe coronary stenusis group(<70% stenosis) and the severe coronary stenosis group(≥70% stenosis).The diagnostic model was constructed using magnetic field map(MFM) parameters,either individually or in combination with clinical *** performance of the models was evaluated using receiver operating characteristic curves,accuracy,sensitivity,specificity,positive predictive value(PPV) and ne gative predictive value(NPV).Calibration plots and decision curve analysis were performed to investigate the clinical utility and performance of the models,*** In the severe coronary stenosis group,QR_MCTDd,S_MDp,and TT_(MA)C_(50) were significantly higher than those in the non-severe coronary stenosis group(10,46±10.66 vs,5.11±6.07,P <0.001;7.2±8.64 vs.4.68±6.95,P=0.003;0.32±57.29 vs.0.26±57.29,P <0.001).While,QR_MV_(amp),R_(MA),and T_(MA) in the severe coronary stenosis group were lower(0.23±0.16 vs.0.28±0.16,P<0.001;55.06±48.68 vs.59.24±53.01,P<0.001;51.67±39.32 vs. 60.45±51.33,P <0.001).Seven MFM parameters were integrated into the model,resulting in an area under the curve of 0.810(95% CI:0.765-0.855).The sensitivity,specificity,PPV,NPV,and accurecy were 71.7%,80.4%,93.3%,42.8 %,and 73.5%;*** combined model exhibited an area under the curve of 0.845(95% CI:0.798-0.892).The sensitivity,specificity,PPV,NPV,and accuracy were 84.3%,73.8%,92.6%,54.6%,and 82.1%;*** curves demonstrate d excellent agreement between the nomogram prediction and actual *** decision curve analysis showed that the c ombine d model provided greater net benefit compared to the magnetocardingraphy model.C

关键词： coronary stenosis specificity

Laser-rewritable room temperature phosphorescence based on in-situ polymerized tartaric acid

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Science China Chemistry 2024年第9期67卷 3029-3038页

作者： Tuo-Yu Zhou Tai-Wen Li Hai-Fu Zhang Rui-Lin Chai Qian Zhao Penglin Zhang Guang-Yue Li Qian-Wen Wang Chang Li Yu Shu Zhi Fan sheng-hua Li College of Chemical Engineering and Materials Science College of SciencesTianjin University of Science&TechnologyTianjin 300457China College of Chemical Engineering North China University of Science and TechnologyTangshan 063210China Tianjin Key Laboratory of Multiplexed Identification for Port Hazardous Chemicals Tianjin University of Science&TechnologyTianjin 300457China

Organic room temperature phosphorescence(RTP)materials have potential applications in information technology and ***,the precise control of the afterglow in reversible manners remains challenging for organic ***,we report a kind of organic RTP material fabricated by simple heating mixtures of tartaric acid(TA)and aromatic acids,which can switch their phosphorescence by *** mixtures show tunable phosphorescence from indigo to orange with phosphorescence efficiency of up to 53.99% due to locking different organic luminogens by the TA-formed matrix through the noncovalent *** afterglow of those materials lasts a few seconds and disappears by water fumigation,which can be repeated in response to wet/heat *** drop-casting those materials on glass slides,a laser-repatternable phosphorescence is achieved by facile laser direct writing and quenched by water *** results open the opportunity for the design of smart stimuli-responsive phosphorescence materials from sustainable natural products.

关键词： room temperature phosphorescence tunable afterglows tartaric acid laser direct writing stimuli-response

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Rare earth element-modified MOF materials:synthesis and photocatalytic applications in environmental remediation

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Rare Metals 2024年第4期43卷 1390-1406页

作者： Shu-Kun Le Qi-Jie Jin Jia-Ao Han hua-Cong Zhou Quan-sheng Liu Fu Yang Jie Miao Pei-Pei Liu Cheng-Zhang Zhu Hai-Tao Xu Inner Mongolia Key Laboratory of High-Value Functional Utilization of Low Rank Carbon Resources Chemical Engineering CollegeInner Mongolia University of TechnologyHohhot010050China School of Environmental Science and Engineering Nanjing Tech UniversityNanjing210009China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang212100China Institut National de la Recherche Scientifique-Énergie Matériaux et Télécommunications MontrealQCJ3X 1P7Canada

Metal-organic framework-like materials(MOFs)have been developed in the fields of photocatalysis for their excellent optical properties and physicochemical properties,including environmental remediation,CO_(2)photoreduction,water splitting,and so *** their important roles in various fields,rare earth elements have received growing interests from *** MOFs with rare earth elements for modification allows broadening the absorption spectrum,while the active electrons on their empty 4f orbitals can act as traps to capture photoexcited carriers to inhibit the recombination of electron-hole pairs,thus promoting photocatalytic ***,rare earth elements modified MOFs provide an attractive way to achieve their high value *** this mini-review,the synthesis of rare earth element-modified MOFs photocatalysts and corresponding applications in the removal of antibiotics,CO_(2)reduction,and hydrogen production are constructively summarized and ***,the latest advancements and current difficulties of these materials as well as the application prospects are also provided.

关键词： Rare earth metals MOFs Photocatalytic CO_(2) reduction Environmental remediation Water splitting

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试验研究层间错动带动孔压增长的影响因素

科学技术与工程 2017年第22期17卷 177-181页

作者：朱凌裴向军崔圣华孟祥瑞地质灾害防治与地质环境保护国家重点实验室(成都理工大学) 成都610059

对大光包滑坡层间错动带材料进行动三轴试验,研究在不同条件下动孔压的增长特性,试验结果表明:(1)频率对动孔压的增长没有影响,不同频率下试样达到液化的时间基本相同;(2)动应力越大,孔压增长越快,达到液化需要的振次越少;(3)饱和度对... 详细信息

对大光包滑坡层间错动带材料进行动三轴试验,研究在不同条件下动孔压的增长特性,试验结果表明:(1)频率对动孔压的增长没有影响,不同频率下试样达到液化的时间基本相同;(2)动应力越大,孔压增长越快,达到液化需要的振次越少;(3)饱和度对动孔压的增长有较大影响,饱和度越高,样品动孔压增长越快,达到液化需要的振次越少;饱和度降低,动孔压的增速减缓,在应变达到5%时样品没有液化;(4)干密度越小,动孔压增长越快;干密度越大,颗粒之间的咬合力和摩阻力越大,孔压增长缓慢。

关键词：层间错动带动三轴试验动孔压

Comparative analysis of primate and pig cells reveals primate-specific PINK1 expression and phosphorylation

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Zoological Research 2024年第2期45卷 242-252页

作者： Xiu-sheng Chen Rui Han Yan-Ting Liu Wei huang Qi Wang Xin Xiong Ying Zhang Jian-Guo Zhao Shi-hua Li Xiao-Jiang Li Wei-Li Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)GHM Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong 510632China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Beijing Institute for Stem Cell and Regenerative Medicine Beijing 100101China University of Chinese Academy of Sciences Beijing 100049China

PTEN-induced putative kinase 1(PINK1),a mitochondrial kinase that phosphorylates Parkin and other proteins,plays a crucial role in mitophagy and protection against *** in PINK1 and Parkin can lead to loss of function and early onset Parkinson's ***,there is a lack of strong in vivo evidence in rodent models to support the theory that loss of PINK1 affects mitophagy and induces ***,PINK1 knockout pigs(Sus scrofa)do not appear to exhibit *** our recent work involving non-human primates,we found that PINK1 is selectively expressed in primate brains,while absent in rodent *** extend this to other species,we used multiple antibodies to examine the expression of PINK1 in pig *** contrast to tissues from cynomolgus monkeys(Macaca fascicularis),our data did not convincingly demonstrate detectable PINK1expression in pig *** of PINK1 in cultured pig cells did not result in altered Parkin and BAD phosphorylation,as observed in cultured monkey cells.A comparison of monkey and pig striatum revealed more PINK1-phosphorylated substrates in the monkey ***,PINK1 knockout in pigs did not lead to obvious changes in the phosphorylation of Parkin and *** findings provide new evidence that PINK1expression is specific to primates,underscoring the importance of non-human primates in investigating PINK1function and pathology related to PINK1 deficiency.

关键词： PINK1 Parkin Mitochondria Phosphorylation Non-human primates Pigs

Dynamic foraging strategy adaptation to heterogeneous environments contributes to social aggregation in snub-nosed monkeys

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Zoological Research 2024年第1期45卷 39-54页

作者： Lan Zhao sheng-Nan Ji Xiao-Bing Du Jia-Hui Liu Bo-Lun Zhang Pei-hua Li Yi-Jun Yang Bao-Guo Li Yan-Qing Guo Xiao-Guang Qi College of Life Sciences Northwest UniversityXi’anShaanxi 710069China Chengdu Institute of Biology Chinese Academy of SciencesChengduSichuan 610041China State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China

The dynamics of animal social structures are heavily influenced by environmental patterns of competition and *** folivorous colobine primates,prevailing theories suggest that larger group sizes should be favored in rainforests with a year-round abundance of food,thereby reducing feeding ***,paradoxically,larger groups are frequently found in high-altitude or high-latitude montane ecosystems characterized by a seasonal scarcity of *** contradiction is posited to arise from cooperative benefits in heterogeneous *** investigate this hypothesis,we carried out a six-year field study on two neighboring groups of golden snub-nosed monkey(Rhinopithecus roxellana),a species representing the northernmost distribution of colobine *** showed that the groups adjusted their movement and habitat selection in response to fluctuating climates and spatiotemporal variability of resources,indicative of a dynamic foraging ***,during the cold,resource-scarce conditions in winter,the large group occupied food-rich habitats but did not exhibit significantly longer daily travel distances than the smaller neighboring ***,we compiled an eco-behavioral dataset of 52 colobine species to explore their evolutionary *** of this dataset suggested that the increase in group size may have evolved via home range expansion in response to the cold and heterogeneous climates found at higher altitudes or ***,we developed a multi-benefits framework to interpret the formation of larger groups by integrating environmental *** cold and diverse environments,even smaller groups require larger home ranges to meet their dynamic survival *** spatiotemporal distribution of high-quality resources within these expanded home ranges facilitates more frequent interactions between groups,thereby encouraging social aggregation into larger *** process enhances the benefits of collabor

关键词： Social evolution Folivore paradox MLS Rhinopithecus roxellana Multi-benefits framework

对置活塞二冲程柴油机双喷油器碰撞喷雾试验研究

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兵工学报 2017年第10期38卷 1881-1890页

作者：刘宇航赵振峰张付军谢钊毅鲁怡崔华盛北京理工大学机械与车辆学院北京100081 广州汽车集团股份有限公司汽车工程研究院广东广州511434

为了获得良好的混合气,保证燃烧室形状、喷雾特性及缸内气体流动之间有良好的匹配,针对对置活塞二冲程柴油机燃烧室的喷雾特性,使用纹影法结合图像处理技术分析了喷油器布置方案、喷射压力、定容弹弹体压力和喷油持续期对油束贯穿距离... 详细信息

为了获得良好的混合气,保证燃烧室形状、喷雾特性及缸内气体流动之间有良好的匹配,针对对置活塞二冲程柴油机燃烧室的喷雾特性,使用纹影法结合图像处理技术分析了喷油器布置方案、喷射压力、定容弹弹体压力和喷油持续期对油束贯穿距离及喷雾空间扩散率的影响。研究结果表明:在喷射压力75 MPa、弹体压力2 MPa、喷油持续期1.5 ms的工况下,双喷油器布置方案与单喷油器布置方案相比,空间扩散率更高,更有利于燃油的雾化;喷射压力的提高有利于燃油在空间的扩散,但近壁区内分布的燃油会随着喷射压力的提高而增加,造成"湿壁"现象;弹体压力过小会使油雾在壁面附近形成浓混合气区域,过大的弹体压力又会使燃油更多集中在中心区域;随着喷油持续期的增加,油束贯穿距离和空间扩散率的增加越来越不明显。

关键词：动力机械工程碰撞喷雾纹影法双喷油器试验研究

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金属导热理论的研究进展与前沿问题

物理学报 2024年第3期73卷 31-42页

作者：王奥盛宇飞鲍华上海交通大学溥渊未来技术学院上海200240 上海交通大学密西根学院上海200240

金属是人类使用最广泛的材料之一.相对于对金属力学性能的研究,金属导热性能的相关研究较为匮乏.对金属导热机制的理解往往还依赖于一百多年前建立的威德曼-弗朗兹定律.金属导热和电子输运有密切联系,同时又与晶格振动有关.深入理解金... 详细信息

金属是人类使用最广泛的材料之一.相对于对金属力学性能的研究,金属导热性能的相关研究较为匮乏.对金属导热机制的理解往往还依赖于一百多年前建立的威德曼-弗朗兹定律.金属导热和电子输运有密切联系,同时又与晶格振动有关.深入理解金属导热机制,不但对材料应用意义重大,而且有利于提高对导热基本理论的认知.本文回顾了金属导热研究的历史,并对最近十几年来金属导热的研究进行了总结,特别是对基于第一原理电子-声子耦合模式分析的金属导热机理的研究进行了综述.此外,本文也对金属导热理论的未来发展方向进行了探讨.

关键词：热导率电子导热声子导热洛伦兹数

Study on the preservation effects of the amputated forelimb by machine perfusion at physiological temperature

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Chinese Journal of Traumatology 2024年第2期27卷 114-120页

作者： sheng-Feng Chen Bo-Yao Yang Tie-Yuan Zhang Xiang-Yu Song Zhi-Bo Jia Lei-Jia Chen Meng-Yi cui Wen-Jing Xu Jiang Peng Guizhou Medical University Guiyang550025China Medical School of PLA Beijing100048 China Beijing Key Lab of Regenerative Medicine in Orthopedics Key Laboratory of Musculoskeletal Trauma and War Injuries PLADepartment of OrthopedicsThe Fourth Medical CenterChinese PLA General HospitalBeijing100048China Hebei North Universiy Zhangjiakou075000Hebei ProvinceChina

Purpose:Ischemia and hypoxia are the main factors limiting limb replantation and *** cold storage(SCS),a common preservation method for tissues and organs,can only prolong limb ischemia time to 4-6 *** normothermic machine perfusion(NMP)is a promising method for the preservation of tissues and organs,which can extend the preservation time in vitro by providing continuous oxygen and *** study aimed to evaluate the difference in the efficacy of the 2 limb preservation ***:The 6 forelimbs from beagle dogs were divided into 2 *** the SCS group(n=3),the limbs were preserved in a sterile refrigerator at 4°C for 24 h,and in the NMP group(n=3),the perfusate prepared with autologous blood was used for the oxygenated machine perfusion at physiological temperature for 24 h,and the solution was changed every 6 *** effects of limb storage were evaluated by weight gain,perfusate biochemical analysis,enzyme-linked immunosorbent assay,and histological *** statistical analyses and graphs were performed using GraphPad Prism 9.0 one-way or two-way analysis of *** p value of less than 0.05 was considered to indicate statistical ***:In the NMP group,the weight gained percentage was 11.72%±4.06%;the hypoxia-inducible factor-1αcontents showed no significant changes;the shape of muscle fibers was normal;the gap between muscle fibers slightly increased,showing the intercellular distance of(30.19±2.83)μm;and the vascularα-smooth muscle actin(α-SMA)contents were lower than those in the normal blood *** creatine kinase level in the perfusate of the NMP group increased from the beginning of perfusion,decreased after each perfusate change,and remained stable at the end of perfusion showing a peak level of 4097.6 U/*** lactate dehydrogenase level of the NMP group increased near the end of perfusion and reached the peak level of 374.4 U/*** the SCS group,the percentage of weight gain was 0.18%±0.10%,a

关键词： Traumatic amputation Machine perfusion Static cold storage Limb replantation