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Splitting Rolling Simulated by Reproducing Kernel Particle Method

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Journal of Iron and Steel Research International 2007年第3期14卷 42-46页

作者： cui qing-ling LIU Xiang-hua WANG Guo-dong State Key Laboratory of Rolling and Automation Northeastern University Shenyang 110004 Liaoning China

During splitting rolling simulation, re-meshing is necessary to prevent the effect of severe mesh distortion when the conventional finite element method is used. However, extreme deformation cannot be solved by the finite element method in splitting rolling. The reproducing kernel particle method can solve this problem because the continuum body is discretized by a set of nodes, and a finite element mesh is unnecessary, and there is no explicit limitation of mesh when the metal is split. To ensure stability in the large deformation elastoplastic analysis, the Lagrange material shape function was introduced. The transformation method was utilized to impose the essential boundary conditions. The splitting rolling method was simulated and the simulation results were in accordance with the experimental ones in the literature.

关键词： elasto-plasticity large deformation reproducing kernel particle method splitting rolling

HE4、CA125及CA153在卵巢良性肿瘤诊断中的临床应用价值分析

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中国实用医药 2024年第19期19卷 29-32页

作者：欧阳海红刘晔崔秀青上栗县人民医院检验科 337009

目的研究血清人附睾蛋白4(HE4)、糖类抗原125(CA125)及糖类抗原153(CA153)在卵巢良性肿瘤诊断中的临床应用价值。方法选取41例卵巢良性肿瘤患者作为研究对象,将其按照病理检查结果的差异分为子宫内膜异位症组(n=18)及其他卵巢良性肿瘤... 详细信息

目的研究血清人附睾蛋白4(HE4)、糖类抗原125(CA125)及糖类抗原153(CA153)在卵巢良性肿瘤诊断中的临床应用价值。方法选取41例卵巢良性肿瘤患者作为研究对象,将其按照病理检查结果的差异分为子宫内膜异位症组(n=18)及其他卵巢良性肿瘤组(n=23)。检测并对比两组血清HE4、CA125、CA153水平。以受试者工作特征曲线(ROC曲线)分析血清HE4、CA125、CA153水平诊断子宫内膜异位症的效能。对比两组患者手术前后血清HE4、CA125、CA153水平。以Pearson相关性分析明确子宫内膜异位症患者血清HE4、CA125、CA153三项指标间的相关性。结果子宫内膜异位症组血清HE4、CA125、CA153水平分别为(115.10±12.73)pmol/L、(46.71±6.29)U/ml、(28.58±4.60)U/ml,均高于其他卵巢良性肿瘤组的(86.97±10.30)pmol/L、(38.63±4.80)U/ml、(16.83±3.01)U/ml(P<0.05)。经ROC曲线分析证实,血清HE4、CA125、CA153联合诊断子宫内膜异位症的灵敏度、约登指数、曲线下面积均优于HE4、CA125、CA153单独诊断。子宫内膜异位症组及其他卵巢良性肿瘤组患者术后血清HE4、CA125、CA153水平均低于术前(P<0.05)。经Pearson相关性分析证实,子宫内膜异位症患者血清HE4与CA125、HE4与CA153、CA125与CA153均呈正相关(r=0.735、0.766、0.801, P<0.05)。结论血清HE4、CA125、CA153应用于卵巢良性肿瘤诊断中的价值较高,有利于子宫内膜异位症与其他卵巢良性肿瘤的鉴别诊断,且在评估疗效方面可能存在一定价值。

关键词：卵巢良性肿瘤子宫内膜异位症人附睾蛋白4 糖类抗原125 糖类抗原153

国潮文化视域下老字号服装品牌视觉设计研究——以天津老美华服装品牌为例

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西部皮革 2024年第16期46卷 137-139页

作者：荆瑞娟林永莲崔晴天津师范大学美术与设计学院

文章主要探讨了国潮文化发展背景下老美华品牌视觉形象的再设计。文章深入分析国潮文化发展现状及发展趋势，通过对国潮文化的内涵、风格特点、表现形式以及主要内容等方面的解析，总结提炼国潮文化元素在老美华服装品牌设计中的应用法... 详细信息

文章主要探讨了国潮文化发展背景下老美华品牌视觉形象的再设计。文章深入分析国潮文化发展现状及发展趋势，通过对国潮文化的内涵、风格特点、表现形式以及主要内容等方面的解析，总结提炼国潮文化元素在老美华服装品牌设计中的应用法则，挖掘“国潮”文化的精髓，将国潮元素与老美华老字号品牌的视觉设计相融合。通过对老美华品牌理念、品牌标识、产品包装、外观等的再设计，重新构思“老美华”品牌形象，赋予品牌更为丰富的文化内涵，以实现品牌的“年轻化”，推动国货品牌可持续发展，提高国人对中国传统文化的认知和文化自信。

关键词：国潮文化老字号品牌视觉设计老美华服装

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原发性胃上皮样横纹肌肉瘤1例

中国现代普通外科进展 2024年第2期27卷 164-165页

作者：于晋轩薛令凯崔庆滨州医学院第一临床医学院山东滨州256600 滨州医学院附属淄博市中心医院胃肠外科山东淄博255020

1病例资料患者男,66岁,因“上腹部隐痛伴有腹胀8 d”于2022年12月4日至淄博市中心医院就诊。既往高血压病史,血压控制可。入院后完善胃镜及腹部CT。胃镜显示:胃角巨大溃疡,累及胃体小弯侧及胃窦前壁,底覆污秽苔,质脆(图1A);胃窦黏膜充... 详细信息

1病例资料患者男,66岁,因“上腹部隐痛伴有腹胀8 d”于2022年12月4日至淄博市中心医院就诊。既往高血压病史,血压控制可。入院后完善胃镜及腹部CT。胃镜显示:胃角巨大溃疡,累及胃体小弯侧及胃窦前壁,底覆污秽苔,质脆(图1A);胃窦黏膜充血水肿,红白相间,以白为主。胃角取3块组织进行活检。2022年12月5日行腹部CT,显示:胃角小弯侧及胃窦壁明显增厚,以胃角小弯侧为著,最厚处约1.8 cm,累及长度范围约9.8 cm,相应胃腔狭窄,胃周可见小淋巴结(图1B);强化CT显示:增强扫描呈中度不均匀强化,浆膜层欠光整(图1C)。诊断为胃小弯侧及胃窦壁肿瘤,行手术治疗。

关键词：胃肿瘤横纹肌肉瘤

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入侵昆虫菊方翅网蝽卵到成虫期的超微结构

环境昆虫学报 2024年第2期46卷 540-550页

作者：朱玺张家璇李宁宁孟昶君高翠青南京林业大学南方现代林业协同创新中心南京林业大学林草学院南京210037

外来入侵害虫菊方翅网蝽Corythucha marmorata Uhler, 1878(半翅目:网蝽科)自传入我国后分布范围迅速扩张。本文利用扫描电子显微镜对菊方翅网蝽的外部形态进行了深入研究,重点关注了卵、若虫到成虫在个体发育过程中超微结构的变化。卵... 详细信息

外来入侵害虫菊方翅网蝽Corythucha marmorata Uhler, 1878(半翅目:网蝽科)自传入我国后分布范围迅速扩张。本文利用扫描电子显微镜对菊方翅网蝽的外部形态进行了深入研究,重点关注了卵、若虫到成虫在个体发育过程中超微结构的变化。卵表面光滑,卵盖具蜂窝状小室。1~3龄若虫触角3节,4龄若虫至成虫,鞭节分为2节;在触角上发现了5类感器:2类毛形感器(Sensilla Trichodea)和3类锥形感器(Sensilla Basiconica);在若虫阶段发现了4种类型的体表突起:鳞片状突起、三角形突起、棒状突起和短柄蘑菇状突起,在发育过程中数量增加;1龄若虫体表瘤突简单,与2~5龄不同,后者瘤突结构保持不变,但分枝变多、变长。研究结果有助于入侵害虫菊方翅网蝽的早期识别,并为相关类群的系统发育分析提供更多数据。

关键词：入侵昆虫形态个体发育胚后发育异翅亚目

CONTINUOUS IMPROVEMENT THROUGH INTEGRATION OF QUALITY TOOLS

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Chinese Journal of Mechanical Engineering 2006年第1期19卷 72-75页

作者： HE Zhen ZOU Feng cui qing＇an QI Ershi LlU Zixian School of Management Tianjin University Tianjin 300072 China

The relationship between major quality tools such as quality function development （QFD）, failure mode and effects analysis （FMEA）, design of experiments （DOE） and statistical process control （SPC） is analyzed through an extensive review of the literature and the concurrent quality engineering philosophy, and a basic structure for the integration of quality tools is presented. An integrated quality management system （IQMS） is developed using C＋＋ Builder, running in the Windows 2000 Server environment with the basic internet connections, and SQL Server 2000 as the platform for developing the database, An illustrative example applying IQMS to the continuous quality improvement for a crane equipment manufacturing is reported. The result shows that the application of IQMS can optimize the process of design and manufacturing, shorten the cycle time of product, reduce the cost, and realize quality improvement continuously, The proposed integrated framework with IOMS is believed to be applicable to continuous quality improvement in many manufacturing companies.

关键词： Concurrent quality engineering Integration of quality Continuous improvement Integrated quality management system (IQMS)

The new synthesis of sesquiterpenoids 10-bromo-α-chamigrene

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Chinese Chemical Letters 2009年第5期20卷 554-556页

作者： qing cui Lin Kang Hai Shen Yang Xiao Hua Xu State Key Laboratory of Elemento-Organic Chemistry Nankai University Tianjin 300071 China

The new synthesis of 10-bromo-α-chamigrene was achieved as follows; 6-methyl-5-heptene-2-one was transformed into corresponding thioacetals, and then successively treated with Cp2Ti（P（OEt）3）2. The intermediate reacted with mono-ketal of cyclohexane-1,4-dione, and gave the carbonyl coupling product. It was then transformed into the key intermediate γ-bisabolene via deketalization, Grignard reaction, dehydration and then furnished the target molecule by polyene cyclization, with total yield 2%. All structures were confirmed by ^1H NMR and ^13C NMR. The final compound was confirmed by ^1H NMR, ^13C NMR and MS.

关键词： 10-Bromo-α-chamigrene Halogenated sesquiterpenoids Carbonyl coupling Synthesis

First synthesis of (±)-cedarmycin B

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Chinese Chemical Letters 2009年第9期20卷 1023-1024页

作者： Hai Shen Yang Xiao Xiao Qiao qing cui Xiao Hua Xu State Key Laboratory of Elemento-Organic Chemistry Nankai University Tianjin 300071 China

The synthesis of racemic cedannycin B, an antibiotic from Streptomyces sp. TP-A0456 was achieved firstly from γ- butyrolactone. The key step was a Barbier-type addition of 3-bromomethyl-5H-furan-2-one to formaldehyde mediated by zinc, which afforded the sole γ-addition product 4-hydroxymethyl-3-methylene-dihydrofuran-2-one. The final compound was confirmed by 1H NMR, 13C NMR and HRMS. 2009 Xiao Hua Xu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Cedarrnycin B Antibiotic Streptomyces sp. Barbier reaction 3-Bromomethyl-5H-furan-2-one

Modulating Effects of Chlorogenic Acid on Lipids and Glucose Metabolism and Expression of Hepatic Peroxisome Proliferator-activated Receptor-α in Golden Hamsters Fed on High Fat Diet

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Biomedical and Environmental Sciences 2009年第2期22卷 122-129页

作者： SHU-YUAN LI cui-qing CHANG FU-YING MA AND CHANG-LONG YU Division of Nutrition and Biochemistry Institute of Sports Medicine Third Hospital Peking University Beijing 100191 China Department of Pediatrics General Hospital of Chinese People's Armed Police Forces Beijing 100039 China

Objective To examine the effects of chlorogenic acid （CGA） on lipid and glucose metabolism under a high dietary fat burden and to explore the possible role of peroxisome proliferator-activated receptor-α （PPAR-α） in these effects. Methods Twenty male golden hamsters were randomly divided into CGA treatment group （n=10, given peritoneal injection of CGA solution prepared with PBS, 80 mg CGA/kg body weight daily）, and control group （n=10, given PBS i.p. at the average volume of the treatment group）. Animals in both groups were given 15% high fat diet. Eight weeks after treatment with CGA, the level of biochemical parameters in fasting serum and tissues and the expression of hepatic mRNA and protein PPAR-α were determined. Results Eight weeks after treatment with CGA, the levels of fasting serum triglyceride （TG）, free fatty acid （FFA）, total cholesterol （TC）, low density lipoprotein cholesterol （LDL-C）, high density lipoprotein cholesterol （HDL-C）, glucose （FSG）, and insulin （FSI） were significantly lower in the GGA treatment group than in the control group. CGA also led to higher activity of hepatic lipase （HL） lower contents of TG and FFA in liver, and lower activity of lipoprotein lipase （LPL） in skeletal muscle. Furthermore, CGA significantly elevated significantly elevated the expression level of mRNA and protein expression in hepatic PPAR-α. Conclusion CGA can modify lipids and glucose metabolism, which may be attributed to PPAR-α facilitated lipid clearance in liver and improved insulin sensitivity.

关键词： Chlorogenic acid Golden hamster High fat diet Hypolipidemic effect Hypoglycemic effect Lipids clearance FFA drainage PPAR-α Insulin sensitivity